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Development and Prospect of Emulsion Technology in Cosmetics (화장품에서 유화기술의 발전 및 전망)

  • Kyong, Kee-Yeol;Lee, Cheon-Koo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.4 s.59
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    • pp.209-217
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    • 2006
  • Emulsion is a dispersion system among liquids which are not miscible together. There are numerous cosmetic raw materials which have different physicochemical properties. Therefore, emulsion technology is very useful in cosmetics. With the development of emulsifier, several emulsification technologies have been developed. Since HLB method by Griffin in 1950's, PIT method, gel method, and D-phase methods, etc, have been developed. Recently, the application of natural emulsifier and polymeric emulsifier increases in cosmetics in order to achieve enhanced safety and biocompatibility. Besides nano-emulsion, multiple-emulsion, liquid crystal emulsion, and Pickering emulsion have been developed and applied as means of differentiating appearance and texture of products and achieving enhanced delivery of active ingredients. Meanwhile, the application studies of nano-dispersed structural system such as liposome or cubosome are on progress. Liposome is a bi- or multi-lamella layer dispersion system composed of amhiphilic molecules - phospholipids which are main components of plasma membrane. Cubosome also is a nano-sized dispersion system composed of a specific molecule like glyceryl monoloeate derived from natural products. And it has a cubic bicontinuous structure in water due to its unique molecular structure. Incorporating compounds (active materials) into such nano-particles can increase biocompatibility and delivery efficiency of target compounds. Manufacturing process and application of cosmetic emulsions and nano-particles are briefly introduced in this paper.

Performance Analysis of Optimal Neural Network structural BPN based on character value of Hidden node (은닉노드의 특징 값을 기반으로 한 최적신경망 구조의 BPN성능분석)

  • 강경아;이기준;정채영
    • Journal of the Korea Society of Computer and Information
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    • v.5 no.2
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    • pp.30-36
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    • 2000
  • The hidden node plays a role of the functional units that classifies the features of input pattern in the given question. Therefore, a neural network that consists of the number of a suitable optimum hidden node has be on the rise as a factor that has an important effect upon a result. However there is a problem that decides the number of hidden nodes based on back-propagation learning algorithm. If the number of hidden nodes is designated very small perfect learning is not done because the input pattern given cannot be classified enough. On the other hand, if designated a lot, overfitting occurs due to the unnecessary execution of operation and extravagance of memory point. So, the recognition rate is been law and the generality is fallen. Therefore, this paper suggests a method that decides the number of neural network node with feature information consisted of the parameter of learning algorithm. It excludes a node in the Pruning target, that has a maximum value among the feature value obtained and compares the average of the rest of hidden node feature value with the feature value of each hidden node, and then would like to improve the learning speed of neural network deciding the optimum structure of the multi-layer neural network as pruning the hidden node that has the feature value smaller than the average.

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A Political-Economic Study on Cooperative Squid Fishing East to the $E128^{\circ}$ (동경 128도 이동 오징어 공조조업에 관한 정치경제학적 연구)

  • Park Seong-Kwae
    • The Journal of Fisheries Business Administration
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    • v.35 no.2
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    • pp.91-115
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    • 2004
  • The main purpose of this study is to analyze the cooperative squid fisheries problems surrounding the $E128^{\circ}$, established by the 1965 Korea - Japan Fisheries Agreement which banned Korean large trawlers' fishing east to the $E128^{\circ}$ In fact, the moratorium was put on by Japans request. However, such issue did not occur until the filefish stock in the southern Korean sea, which was a major target fish species of the large trawl fisheries, The filefish stock collapsed completely around 1991 and at the same time most of bottom fish stocks in the East China Sea began to show a symptom of over - exploitation. Thus, the off - shore large trawlers learned to have a little opportunity of finding out alternative fish stocks as well as fishing grounds. Fortunately, at that time squid resource stock and consumption were on the increasing trend. The large trawl fisheries were able to economically exploit squid stock east to the $E128^{\circ}$ through cooperative fishing with squid angling light boats in the East and East - South Sea, even though such cooperative fishing activities violate the existing fishery laws apparently. Some important reasons that the large trawlers have continued the cooperative fishing seem to be because (ⅰ) squid resource stock has been on the increasing state over time, (ⅱ) the trawl fisheries have made a significant contribution to meeting domestic and export demands and stabilizing squid prices, and (ⅲ) they have kept domestic squid market from foreign competition. However, the new Korea - Japan fisheries agreement in 1998 provided a momentum of questioning the effectiveness of the $E128^{\circ}$ by the squid - related fisheries other than the squid angling. Serious conflicts between squid - related fisheries began to emerge and to be much intensified. Squid angling industries in the East opposed to large trawlers's efforts to formalize such illegal cooperative squid fishing activities. Their main argument was that such formalizing would definitely make the East coast squid prices lower and in turn their business performance would be worse off. The results of quantitative analysis suggest that the trawlers' massive landing may have a significant influence on lowering the east coast squid prices. Now, an important issue that the squid - related fisheries and the government are facing is to solve such complex squid fishing problems through a multi - participatory negotiation process, including price stabilization, total allowable catch level and its operation schemes, $E128^{\circ}$ rearrangement, and so on.

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Development of real-time PCR for rapid detection of Mycobacterium bovis DNA in cattle lymph nodes and differentiation of M. bovis and M. tuberculosis (소 림프절에서 Mycobacterium bovis DNA의 신속 검출과 M. bovis와 M. tuberculosis 감별을 위한 real-time PCR 개발)

  • Koh, Ba-Ra-Da;Jang, Young-Boo;Ku, Bok-Kyung;Cho, Ho-Seong;Bae, Seong-Yeol;Na, Ho-Myung;Park, Seong-Do;Kim, Yong-Hwan;Mun, Yong-Un
    • Korean Journal of Veterinary Service
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    • v.34 no.4
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    • pp.321-331
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    • 2011
  • Mycobacterium bovis, a member of the M. tuberculosis complex (MTC), is the causative agent of bovine tuberculosis. Detection of M. bovis and M. tuberculosis using conventional culture- and biochemical-based assays is time-consuming. Therefore, a simple and sensitive molecular assay for rapid detection would be of great help in specific situations such as faster diagnosis of bovine tuberculosis (bTB) infection in the abattoirs. We developed a novel multiplex real-time PCR assay which was applied directly to biological samples with evidence of bTB and it was allowed to differentiate between M. bovis and M. tuberculosis. The primers and TaqMan probes were designed to target the IS1081 gene, the multi-copy insertion element in the MTC and the 12.7-kb fragment which presents in M. tuberculosis, not in the M. bovis genome. The assay was optimized and validated by testing 10 species of mycobacteria including M. bovis and M. tuberculosis, and 10 other bacterial species such as Escherichia coli, and cattle lymph nodes (n=113). The tests identified 96.4% (27/28) as M. bovis from the MTC-positive bTB samples using conventional PCR for specific insertion elements IS1081. And MTC-negative bTB samples (n=85) were tested using conventional PCR and the real-time PCR. When comparative analyses were conducted on all bovine samples, using conventional PCR as the gold standard, the relative accuracy of real-time PCR was 99.1%, the relative specificity was 100%, and the agreement quotient (kappa) was 0.976. The detection limits of the real-time PCR assays for M. bovis and M. tuberculosis genomic DNA were 10 fg and 0.1 pg per PCR reaction, respectively. Consequently, this multiplex real-time PCR assay is a useful diagnotic tool for the identification of MTC and differentiation of M. bovis and M. tuberculosis, as well as the epidemiologic surveillance of animals slaughtered in abattoir.

Directions and Assignments of Educational Welfare in Korea (우리나라 교육복지의 방향과 과제)

  • Hong, Bong-Sun
    • Korean Journal of Social Welfare
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    • v.56 no.1
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    • pp.253-282
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    • 2004
  • The study is to examine the actual conditions and problems of educational welfare which is a part of social welfare and to offer its future directions and things to do. First of all, education has been considered to be part of social welfare in developed countries for a long time and it has been used the same as school educational welfare. These days Korea is confronted with increasing needs of educational welfare caused by emphasis of manpower, appearance of new poor class after IMF, handing down poverty to their children, absence of public education and educational fever, stress of life long learning and extending needs of students' social welfare service. In advanced countries compared to Korea, people perceive education as an equal opportunity. To reach this thesis, various efforts have been making in terms of manpower development such as reform of related laws, financial and official support, offering of parental skills and protecting children for the disadvantaged, dispatching school social workers and overall life improvement. The subjects and age of educational welfare are also diverse ranging from poor families and pre school children to general public and adults. On the other hand, Korea lacks related laws and financial support that are supposed to enforce educational welfare systematically. Also integrated and professional services are not often available due to the lack of cooperation between related agencies. Therefore, government's role and responsibility should be defined clearly in the future directions of educational welfare in Korea. For this, it is needed to establish related laws and build a concrete financial and executive interrelationship. Also every person should be a target of educational welfare putting priorities on the disadvantaged. A lot of efforts should be made to achieve things mentioned above. Multi-dimensional approach intertwined with education, welfare and labour, establishment of cooperation system between related agencies, reinforcement of life long learning, extension of free education including infants and toddlers, and offering financial support to the poor are a few among these efforts. Finally, institutionalization of school social welfare and improvement school facilities are strongly recommended to get to the right track of educational welfare.

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A Preliminary Study of Virtual-micro Intensity Modulated Radiation Therapy (가상 미세 세기조절방사선치료(Virtual micro-IMRT;VMIMRT) 기법의 임상 적용을 위한 예비적 연구)

  • 김상노;조병철;서택석;배훈식;최보영;이형구
    • Progress in Medical Physics
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    • v.13 no.1
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    • pp.32-36
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    • 2002
  • For Intensity Modulated Radiation Therapy(IMRT), the spatial resolution of intensity map(IM) is limited by the width of multi-leaf collimator, which would make an effect on the conformity of the target, as well as organs at risk. Several Methods are suggested to increase the spatial resolution, which can be categorized by the hardware-dependent technique and the software-based technique. However the best solution might be to make the width of MLC finer. it has several obstacles in the respects of technical difficulty and cost. This preliminary study is designed to investigate the clinical effectiveness of the virtual-micro IMRT(VMIMRT) technique, one of the software-based technique. A particular intensity map was created, which has 42$\times$54 pixel dimension ,0.5cm pixel size and 15 intensity levels. Using this intensity map, segment fields of IMRT were generated with 1$\times$lcm, 0.5$\times$1cm, 0.5$\times$0.5cm(VMIM) beamlet size, respectively As results, we found that there was no evidence of improvement for VMIMRT, compared with the 0.5$\times$lcm beamlet size which can be delivered by 1cm width MLC. The reason seems to be due to the constraint of VMIMRT. Further study is required to prove the benefit of the VIMRT in clinical case like head and neck cancer, where is expected that higher resolution than 1cm is necessary.

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A study of quantitative correlation between step animation and emotional expressions (스텝 애니메이션과 감성 표현 사이의 정량적 상호관계에 관한 연구)

  • Lee, Ji-Sung;Jeong, Jae-Wook
    • Archives of design research
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    • v.17 no.4
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    • pp.141-148
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    • 2004
  • The purpose of this study is to define the emotion that expressed in step animation and to quantify the intuitional expression of emotion that related step for using extract, measure, analysis the stimulate element about step. The survey of relation with 27 word of emotional expressions and 36 moving pictures of step sample is used for method of this test. The emotional mental structure is transferred to 2 dimensional planes as applying the results of analysis of integrated data using Quantification Method 3, which the integrated data is composed two axial - confidential axial and stabling axial. Analysis of distribution of 2 dimensional diagram shows that the second of the plane and the third of the plane have much data. However, the first of the plane and the forth of the plane have a little data. Through this kind of analysis of graph, it is difficult to express a different emotion between unstable the timidity mind and stable feel the timidity mind using only step analysis. Six difference types about physical elements affecting to emotion are selected and analyzed such as the paces of step, the rate of step, the movement angle of pelvis, the swing range of arm, angle of backbone and the lean angle of body. The result is that the rate of stop and the lean angle of body are the major element that effects to emotional stimulate of stop. This thesis argues about methods transforming subjective expression to objective and quantitative expression with the state of delicate emotion of character apply to step animation naturally. Those data to apply to multi-contents in future are the main target in this study.

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A TransGate System for Convenient Wireless Internet Contents Generation (편리한 무선인터넷 컨텐츠 생성을 위한 TransGate 시스템)

  • Ryu Dong-Yeop;Han Seung-Hyun;Lim Young-Whan
    • Journal of Internet Computing and Services
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    • v.7 no.2
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    • pp.37-52
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    • 2006
  • A mobile device like ceil phone is the necessity of modern people, of ich con be easily connected to a wireless internet through such a mobile device. The demand for a wireless data communication is growing rapidly. However, agencies have not yet completed standardization of a markup language. Due to the development of the Mobile Device, agencies in this field have provided different data formats with each Mobile Device Platform. Traditionally, contents is hand-tailored to suit the target device. A key problem is that the characteristics and capabilities of the mobile device are too diverse to service the most suitable mobile contents. Because of these problems, the need for a re-usable document description language increases. In this paper, we defined Template file that is common data to service mobile devices. We proposed a method that could be an effective wireless web service though design and the implementation of the Call manager & the XSL Generator. In the methodology, when requesting a wireless internet service, a mobile device finds out markup language and a hardware specification of the mobile device through the Call Manager component supports. The XSL Generator component creates the XSL file dynamically that is the most suitable to a device. Finally, contents is serviced to each device by XSLT. It can generate a wireless page more easily by reusing the existing web contents through such course. Therefore, it can save the time and expense for generating a wireless page.

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Effect of Area deprivation and Social capital on Self rated health among Koreans (한국사회의 지역박탈과 사회적 자본이 주관적 건강수준에 미치는 영향)

  • Park, Eun-Joo;Yeon, Mi-Yeon;Kim, Chul-Woung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.10
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    • pp.382-395
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    • 2016
  • The purpose of this study is to examine how area characteristics influence the health of a population in a particular area by investigating how area deprivation and social capital influence self-rated health. For this study, a multi-level logistic regression was employed to analyze the data collected by Community Health Survey conducted on a target population of 229,186 living at 253 administrative areas of Korea in 2011. First, an analysis was conducted for subjects who have rated their self-health assessment as 'fair', 'poor', and 'very poor' in a 5 -item response survey. Then, a second analysis was conducted for the same subjects by excluding those with a rating of 'fair'. As a result, we found that area deprivation significantly influenced the population's health, according to our second analysis, while it was not significant according to our first analysis. Moreover, social capital was not significant in both analyses. Area deprivation-although the value of it was not so high-seems to explain the differences of individual self-rated health assessment as a contextual effect. In addition, influence of area characteristics is not limited to certain local areas, but to all local areas of Korea. Therefore, it is suggested that efforts to improve area characteristics are necessary to upgrade the individual's health level. A standardized classification system-distinguishing between good and poor self-rated health-is necessary through further comparative studies on self-rated health assessment.

Design and Implementation of an Efficient Buffer Replacement Method for Real-time Multimedia Databases Environments (실시간 멀티미디어 데이터베이스 환경을 위한 효율적인 버퍼교체 기법 설계 및 구현)

  • 신재룡;피준일;유재수;조기형
    • Journal of Korea Multimedia Society
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    • v.5 no.4
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    • pp.372-385
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    • 2002
  • In this paper, we propose an efficient buffer replacement method for the real-time multimedia data. The proposed method has multi level priority to consider the real-time characteristics. Each priority level is divided into a cold data set that is likely to be referenced for the first time and a hot data set that is likely to be re-referenced. An operation to select the victim data is sequentially executed from the cold set with the minimum priority level to the hot set with the maximum Priority level. It is chosen only at the lower level than or equal to the priority of the transaction that requests a buffer allocation. In the cold set, our method selects a media that has the maximum size in the level for a target of victim first of all. And in the hot set, our method selects a medium that has the maximum interval of the reference first of all. Since it maintains many popular media in the limited buffer space, the buffer hit ratio is increased. It also manages many service requests. As a result, our method improves the overall performance of the system. We compare the proposed method with the Priority-Hints method in terms of the buffer hit ratio and the deadline missing ratio of transactions. It is shown through the performance evaluation that our method outperforms the existing methods.

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