• Title/Summary/Keyword: Multi-Stage process

Search Result 527, Processing Time 0.021 seconds

Effects of three-area laser-assisted zona thinning in 8-cell human embryos on pregnancy outcomes in vitro fertilization

  • Jeong, Ju-Eun;Joo, Bo-Sun;Kim, Chang-Woon;Kim, Hwi-Gon;Joo, Jong-Kil;Lee, Kyu-Sup
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.45 no.1
    • /
    • pp.25-30
    • /
    • 2018
  • Objective: This study conducted a preliminary examination of the effects of three-area laser-assisted zona thinning (LAZT) during the cleavage stage of embryo development on the hatching process in human in vitro fertilization-embryo transfer (IVF-ET) with subjects of advanced female age or frozen-thawed (FT) embryos. Methods: Eight-cell stage embryos were treated with LAZT in three areas of the zona pellucida at $120^{\circ}$ intervals. The control group was embryos without LAZT. Of the 72 consecutive fresh cycles and the 28 FT embryo transfer cycles, the patients in 55 fresh cycles and 17 FT cycles declined LAZT, and those cycles were defined as the control group. Results: In the fresh cycles, the pregnancy rates were similar in the LAZT and control groups. However, in the FT cycles, the pregnancy rate was significantly higher in the LAZT group than in the control group (45.5% in the LAZT group vs. 23.5% in the control group, p< 0.05). Conclusion: These results show that multi-area LAZT resulted in significantly improved pregnancy outcomes in human 8-cell embryos compared to controls.

Structural Changes in Isothermal Crystallization Processes of Synthetic Polymers Studied by Time-Resolved Measurements of Synchrotron-Sourced X-Ray Scatterings and Vibrational Spectra

  • Tashiro, Kohji;Hama, Hisakatsu
    • Macromolecular Research
    • /
    • v.12 no.1
    • /
    • pp.1-10
    • /
    • 2004
  • The structural changes occurring in the isothermal crystallization processes of polyethylene (PE), poly-oxymethylene (POM), and vinylidene fluoridetrifluoroethylene (VDFTrFE) copolymer have been reviewed on the basis of our recent experimental data collected by the time-resolved measurements of synchrotron-sourced wide-angle (WAXS) and small-angle X-ray scatterings (SAXS) and infrared spectra. The temperature jump from the melt to a crystallization temperature could be measured at a cooling rate of 600-1,000 $^{\circ}C$/min, during which we collected the WAXS, SAXS, and infrared spectral data successfully at time intervals of ca. 10 sec. In the case of PE, the infrared spectral data clarified the generation of chain segments of partially disordered trans conformations immediately after the jump. These segments then became transformed into more-regular all-trans-zigzag forms, followed by the formation of an orthorhombic crystal lattice. At this stage, the generation of a stacked lamella structure having an 800-${\AA}$-long period was detected in the SAXS data. This structure was found to transfer successively to a more densely packed lamella structure having a 400-${\AA}$-long period as a result of the secondary crystallization of the amorphous region in-between the original lamellae. As for POM, the formation process of a stacked lamella structure was essentially the same as that mentioned above for PE, as evidenced from the analysis of SAXS and WAXS data. The observation of morphology-sensitive infrared bands revealed the evolution of fully extended helical chains after the generation of lamella having folded chain structures. We speculate that these extended chains exist as taut tie chains passing continuously through the neighboring lamellae. In the isothermal crystallization of VDFTrFE copolymer from the melt, a paraelectric high-temperature phase was detected at first and then it transferred into the ferroelectric low-temperature phase at a later stage. By analyzing the reflection profile of the WAXS data, the structural ordering in the high-temperature phase and the ferroelectric phase transition to the low-temperature phase of the multi-domain structure were traced successfully.

A Study on the Development of DevSecOps through the Combination of Open Source Vulnerability Scanning Tools and the Design of Security Metrics (오픈소스 취약점 점검 도구 및 종합 보안 메트릭 설계를 통한 DevSecOps 구축방안 연구)

  • Yeonghae Choi;Hyeongjun Noh;Seongyun Cho;Hanseong Kang;Dongwan Kim;Suhyun Park;Minjae Cho;Juhyung Lee
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.33 no.4
    • /
    • pp.699-707
    • /
    • 2023
  • DevSecOps is a concept that adds security procedures to the operational procedures of DevOps to respond to the short development and operation cycle. Multi-step vulnerability scanning process should be considered to provide reliable security while supporting rapid development and deployment cycle in DevSecOps. Many open-source vulnerability scanning tools available can be used for each stage of scanning, but there are difficulties in evaluating the security level and identifying the importance of information in integrated operation due to the various functions supported by the tools and different security results. This paper proposes an integrated security metric design plan for scurity results and the combination of open-source scanning tools that can be used in security stage when building the open-source based DevSecOps system.

Derivation of Profit Curve by Cubic Cost Function and Mathematical Verification of Industry Life Cycle: Focused on All Industries in Korea (3차 비용함수에 의한 이익곡선 도출과 산업 라이프사이클의 수리적 검증: 우리나라 전 산업을 중심으로)

  • Hoo Seok Pai;Chae Kwan Lim
    • Journal of Korean Society for Quality Management
    • /
    • v.51 no.4
    • /
    • pp.481-496
    • /
    • 2023
  • Purpose: The main theme of this study is to derive a profit curve by a cubic cost function for nonlinear CVP analysis. According to the analytical approach to derive a nonlinear profit function in this study, it is possible with only the existing cost structure to calculate the profit maximization and downtime point sales unlike the classical CVP analysis. Furthermore, the profit curve by the mathematical model of this study could serve as a tool to quantify the qualitative evaluation of each stage of the industry life cycle. Methods: This study followed the mathematical approach from the cubic cost function model of microeconomics, and using real data of the Bank of Korea Results: The nonlinear profit function suggested by this study is as follows; ${\pi}(x)=-a\left(x-\frac{f}{1-v}\right)^3+(1-v)x-k$ where $a=\frac{1}{3}v\left(\frac{(1-v)}{f}\right)^2,k=f-a\left(1-\frac{f}{1-v \right)^3$ Conclusion: The process and results of this study would be able to contribute not only in practice of nonlinear CVP analysis required in the management accounting or financial management, but also in cost theory of microeconomics. Also, since the life cycle of all industries in Korea was verified to the growth or mature stage, decision makers should pay careful attention to determining life cycle stages and consider the profit curve by the average variable cost ratio over multi periods.

A Function-characteristic Aware Thread-mapping Strategy for an SEDA-based Message Processor in Multi-core Environments (멀티코어 환경에서 SEDA 기반 메시지 처리기의 수행함수 특성을 고려한 쓰레드 매핑 기법)

  • Kang, Heeeun;Park, Sungyong;Lee, Younjeong;Jee, Seungbae
    • Journal of KIISE
    • /
    • v.44 no.1
    • /
    • pp.13-20
    • /
    • 2017
  • A message processor is server software that receives various message formats from clients, creates the corresponding threads to process them, and lastly delivers the results to the destination. Considering that each function of an SEDA-based message processor has its own characteristics such as CPU-bound or IO-bound, this paper proposes a thread-mapping strategy called "FC-TM" (function-characteristic aware thread mapping) that schedules the threads to the cores based on the function characteristics in multi-core environments. This paper assumes that message-processor functions are static in the sense that they are pre-defined when the message processor is built; therefore, we profile each function in advance and map each thread to a core using the information in order to maximize the throughput. The benchmarking results show that the throughput increased by up to a maximum of 72 % compared with the previous studies when the ratio of the IO-bound functions to the CPU-bound functions exceeds a certain percentage.

The Case Study on the Niche Experimentation in Offshore Wind Renewable Energy Transition (해상풍력 기술의 사회-기술시스템 전환과정에 관한 탐색적 사례연구)

  • Kim, Bonggyun;Kim, Dukyoung;Kim, Kyungnam;Kim, Donghwan
    • Journal of Korea Technology Innovation Society
    • /
    • v.17 no.2
    • /
    • pp.355-379
    • /
    • 2014
  • For the transition to the low carbon society, it is inevitable but difficult journey that the new energy technology spread co-exists with formal social system. The objective of offshore wind power plant that has been implemented by the government is to connect large capacity new renewable energy to the central electric power system. Therefore, for the successful introduction of offshore wind power system, the transition of the formal social technology system should be companied. This study analysis the energy system transition about niche strategy adjustment using Multiple Level Perspectives & Strategic Niche Management. It also multi level analyzes and structuralizes the process that new technology, as a research result, evolves through connecting and communicating with formal regime and landscape. Also, adjusting Strategic Niche Management, it diagnoses the obstructive factors in the initial stage of niche experiment and found the major reasons why offshore wind power test plant had been delayed. Through this study, it reaches to the practical implication that offshore niche technology could grow stably in the energy system and various policies.

Premixture Composition Optimization for the Ram Accelerator Performance Enhancement (램 가속기 성능 향상을 위한 예 혼합기 조성비 최적화에 관한 연구)

  • 전용희;이재우;변영환
    • Journal of the Korean Society of Propulsion Engineers
    • /
    • v.4 no.2
    • /
    • pp.21-30
    • /
    • 2000
  • Numerical design optimization techniques are implemented for the improvement of the ram accelerator performance. The design object is to find the minimum ram tube length required to accelerate projectile from initial velocity $V_o$ to target velocity $V_e$. The premixture is composed of $H_2$, $O_2$, $N_2$ and the mole numbers of these species are selected as design variables. The objective function and the constraints are linearized during the optimization process and gradient-based Simplex method and SLP(Sequential Linear Programming) have been employed. With the assumption of two dimensional inviscid flow for internal flow field, the analyses of the nonequilibrium chemical reactions for 8 steps 7 species have been performed. To determined the tube length, ram tube internal flow field is assumed to be in a quasi-steady state and the flow velocity is divided into several subregions with equal interval. Hence the thrust coefficients and accelerations for corresponding subregions are obtained and integrated for the whole velocity region. With the proposed design optimization techniques, the total ram tube length had been reduced 19% within 7 design iterations. This optimization procedure can be directly applied to the multi-stage, multi-premixture ram accelerator design optimization problems.

  • PDF

A STUDY ON A MULTI-LEVEL SUBSTRUCTURING METHOD FOR COMPUTATIONS OF FLUID FLOW (유동계산을 위한 다단계 부분 구조법에 대한 연구)

  • Kim J.W.
    • Journal of computational fluids engineering
    • /
    • v.10 no.2
    • /
    • pp.38-47
    • /
    • 2005
  • Substructuring methods are often used in finite element structural analyses. In this study a multi-level substructuring(MLSS) algorithm is developed and proposed as a possible candidate for finite element fluid solvers. The present algorithm consists of four stages such as a gathering, a condensing, a solving and a scattering stage. At each level, a predetermined number of elements are gathered and condensed to form an element of higher level. At the highest level, each sub-domain consists of only one super-element. Thus, the inversion process of a stiffness matrix associated with internal degrees of freedom of each sub-domain has been replaced by a sequential static condensation of gathered element matrices. The global algebraic system arising from the assembly of each sub-domain matrices is solved using a well-known iterative solver such as the conjugare gradient(CG) or the conjugate gradient squared(CGS) method. A time comparison with CG has been performed on a 2-D Poisson problem. With one domain the computing time by MLSS is comparable with that by CG up to about 260,000 d.o.f. For 263,169 d.o.f using 8 x 8 sub-domains, the time by MLSS is reduced to a value less than $30\%$ of that by CG. The lid-driven cavity problem has been solved for Re = 3200 using the element interpolation degree(Deg.) up to cubic. in this case, preconditioning techniques usually accompanied by iterative solvers are not needed. Finite element formulation for the incompressible flow has been stabilized by a modified residual procedure proposed by Ilinca et al.[9].

Soft-Switched PWM DC-DC High-Power Converter with Quasi Resonant-Poles and Parasitic Reactive Resonant Components of High-Voltage Transformer (부분 공진형 소프트 스위칭 PWM DC-DC 고전압 컨버터)

  • 김용주;신대철
    • The Transactions of the Korean Institute of Power Electronics
    • /
    • v.4 no.4
    • /
    • pp.384-394
    • /
    • 1999
  • This paper deals with a fixed frequency full-bridge inverter type DC-DC high-power converter with high frequency high voltage(HFHV) transformer-coupled stage, which operates under quasi-resonant ZVS transition priciple in spite of a wide PWM-based voltage regulation processing and largely-changed load conditions. This multi-resonant(MR) converter topology is composed of a series capacitor-connected parallel resonant tank which makes the most of parasitic circuit reactive components of HFHV transformer and two additional quasi-resonant pole circuits incorporated into the bridge legs. The soft-switching operation and practical efficacy of this new converter circuit using the latest IGBTs are actually ascertained through 50kV trially-produced converter system operating using 20kHz/30kHz high voltage(HV) transformers which is applied for driving the diagnostic HV X-ray tube load in medical equipments. It is proved from a practical point of view that the switching losses of IGBTs and their electrical dynamic stresses relating to EMI noise can be considerably reduced under a high frequency(HF) switching-based phase-shift PWM control process for a load setting requirements.

  • PDF

A FPGA-based Development of Ultrasonic Level Meter for Measuring Oil Levels of Vehicle Transmissions (차량의 변속기 오일레벨 측정을 위한 FPGA 기반 초음파 레벨 측정기 개발)

  • Kang, Moon-Ho;Park, Yoon-Chang
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.13 no.11
    • /
    • pp.5427-5433
    • /
    • 2012
  • In this paper a ultrasonic level meter for accurately and simply measuring oil levels of vehicle transmission is developed and its effectiveness is shown by experiments. By using a FPGA, all digital signal processes for the oil level calculation is fulfilled, and the programming on a FPGA project IDE enables very short developing time. And besides, analog circuits including a transmit/receive switch, multi-stage active filters and an envelope detect circuit are designed to process low-level ultrasonic echo signal. Under experiments, the designed level meter has proven to have the accuracy of about within 1[mm] scale.