• 제목/요약/키워드: Multi Effect

검색결과 4,500건 처리시간 0.032초

3.0T MRI에서 온도변화가 T1 및 T2 이완시간에 미치는 영향 (Effect of Temperature on T1 and T2 Relaxation Time in 3.0T MRI)

  • 김호현;권순용;임우택;강충환;김경수;김순배;백문영
    • 대한디지털의료영상학회논문지
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    • 제15권2호
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    • pp.63-68
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    • 2013
  • Purpose : The relaxation times of tissue in MRI depend on strength of magnetic field, morphology of nuclear, viscosity, size of molecules and temperature. This study intended to analyze quantitatively that materials' temperatures have effects on T1 and T2 relaxation times without changing of other conditions. Materials and Methods : The equipment was used MAGNETOM SKYRA of 3.0T(SIEMENS, Erlagen, Germany), 32 channel spine coil and Gd-DTPA water concentration phantom. To find out T1 relaxation time, Inversion Recovery Spin Echo sequences were used at 50, 400, 1100, 2500 ms of TI. To find out T2 relaxation time, Multi Echo Spin Echo sequences were used at 30, 60, 90, 120, 150, 180, 210, 240, 270 ms of TE. This experiment was scanned with 5 steps from 25 to $45^{\circ}C$. next, using MRmap(Messroghli, BMC Medical Imaging, 2012) T1 and T2 relaxation times were mapped. on the Piview STAR v5.0(Infinitt, Seoul, Korea) 5 steps were measured as the same ROI, and then mean values were calculated. Correlation between the temperatures and relaxation times were analyzed by SPSS(version 17.0, Chicago, IL, USA). Results : According to increase of temperatures, T1 relaxation times were $214.39{\pm}0.25$, $236.02{\pm}0.87$, $267.47{\pm}0.48$, $299.44{\pm}0.64$, $330.19{\pm}1.72$ ms. T2 relaxation times were $180.17{\pm}0.27$, $197.17{\pm}0.44$, $217.92{\pm}0.39$, $239.89{\pm}0.53$, $257.40{\pm}1.77$ ms. With the correlation analysis, the correlation coefficients of T1 and T2 relaxation times were statistically significant at 0.998 and 0.999 (p< 0.05). Conclusion : T1 and T2 relaxation times are increased as temperature of tissue goes up. In conclusion, we suggest to recognize errors of relaxation time caused local temperature's differences, and consider external factors as well in the quantitative analysis of relaxation time or clinical tests.

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소방공무원의 직무스트레스와 사회심리적 스트레스와의 연관성에 관한 연구 (A Study on the Relationship between Job Stress and Socio-Psychological stress of firefighter)

  • 강병우
    • 한국응급구조학회지
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    • 제13권1호
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    • pp.35-48
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    • 2009
  • Purpose: Firefighters were subjected to be exposed to 24-hour shiftwork and high level of job stress, but there is little study of fire fighters about between Job Stress and Psychological stress in Korea. This study was performed to evaluate job stress of fire fighters grouped by different job types and analyze the health effect of job stress by using a PWI-SF(Psycho-social Well-being Index, Short Form). Methods : This study was to measure the degree of job stress and socio-psychological stress of firefighters working at 119 safety center and analyze the relationship between job stress and mental health, through self-administered questionnaire survey on 918 fire fighters working at fire department located in Korea, during October in 2008. Question items of the questionnaire consist of general characteristics, job stress, and socio-psychological stress. Job Stress Measurement Scale for Koreans was used to measure job stress, while PWI-SF used for socio-psychological stress. Collected data was analyzed through frequency analysis, ${\chi}^2$ test, one-way ANOVA, correlation analysis, multi-regression analysis using a statistic program, SPSS/10.0 Ver for Windows, and statistical significance level was 0.05. Result : Accordingly, this paper is written for the purpose of scrutinizing the reason of 119 rescuers' job stress and Socio-Psychological stress. This thesis tries to analyze a problem and provide contents through many variables concerned and theoretical investigation with the actual research of questionnaire. The results of the study are summarized as follows : Fire fighters feel relatively high stressful in their performance. Job stress, organizational commitment and burnout did not have been influence upon by individual cases such as economic condition, regular exercise etc. Finally, as a result of step by step regression analysis, the variable that can explain Socio-Psychological stress the best was negative emotion scale(NE). Conclusions : It is necessary to conduct repeated studies in the future, since the study implied that there was a contrary relationship between job stress and socio-psychological stress. In order to reduce job stress and maintain better mental health, it is more important than anything else to help firefighters have willingness and efforts to sustain a healthy life, so the development of various programs and education to raise their awareness should be implemented.

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산업보안관리사 자격제도 발전 방안에 대한 고찰 (The Study of a Development Plan of the Industrial Security Expert System)

  • 조용순
    • 시큐리티연구
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    • 제40호
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    • pp.175-207
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    • 2014
  • 산업보안관리사는 현재 민간자격이지만 향후 국가자격화 되어 현장에서 적절하게 활용 가능한 인력인지 여부에 대하여 국가적으로 공신력이 부여될 필요가 있다. 공신력 확보를 위한 운용방안 중 고려할 수 있는 것이 등급제이다. 현재와 같이 단일등급제로 운용할 경우 양적 확산에 초점을 두게 될 가능성이 있다. 따라서 질적 혁신 차원에서 산업보안관리사의 등급제도 활용도를 장기적인 관점에서 검토하여 등급을 구분할 필요가 있다. 한편, 산업보안 현장 실무자의 산업보안관리사 자격시험에 응시할 수 있는 요건, 산업보안 실무연수 과정 이수, 민간자격을 이미 취득한 인력의 경우 국가자격 승계문제도 중요한 고려 사항중 하나이다. 산업보안관리사제도가 활성화 되기 위해서는 국가자격화를 통한 공신력 확보뿐만 아니라 산업보안관리사의 인력의 수요창출이 필요하다. 현재 증가하는 산업기술유출에 대한 우려에도 불구하고 우리기업 등의 보안관리체계의 미비 등 산업보안대응 역량이 상당히 취약한 실정임을 고려할 때, 산업기술 보호에 특화된 산업보안관리체계에 대한 인증을 기존의 정보보호관리체계인증과 별개로 도입할 필요성이 있다. 산업보안 관리체제 인증제도와 산업보안관리사 자격제도가 연동될 때 국가핵심기술 등을 다루는 기업체, 연구기관 등의 산업보안이 실질적으로 이루어져 시너지 효과가 발생할 것이다.

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다제내성 Acinetobacter baumannii의 생장을 억제하는 항생물질을 생산하는 방선균의 분리.동정 및 항균효과 (Isolation and Identification of a Streptomyces sp. that Produces Antibiotics Against Multidrug - Resistant Acinetobacter baumannii)

  • 이기형
    • 한국미생물·생명공학회지
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    • 제39권1호
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    • pp.37-42
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    • 2011
  • 계룡산 지역에서 토양시료를 채취하여 항생제 다제내성균을 효과적으로 제어할 수 있는 항생물질 생산균주를 분리, 탐색하는 과정에서 Streptomyces sp. KH223균주를 선별하였다. 분리균주의 생화학적 특징과 16S ribosomal DNA 유전자 염기서열 분석 결과, 분리균주가 Streptomyces galbus에 속함이 확인되었다. 분리균주의 배양 상등액은 49종의 Acinetobacter baumannii 외 다양한 세균과 진균 등에 항균 활성을 가지고 있었으며 특히 분리균주의 부탄올, 에틸아세테이트 분획물은 10여종의 A. baumannii에 최소생육저해농도 범위 0.8 ${\mu}g$/mL에서 5.0 ${\mu}g$/mL 으로 강한 항균력을 보였으며 기 분리된 cyclo(trp-trp)의 최소생육저해농도 범위 12.5 ${\mu}g$/mL 보다도 강한 항균활성을 나타내었다. 또한 각각의 유기용매 분획물과 cyclo(trp-trp)은 Candida albicans IFO 6258, Bacillus subtilis IAM 1069, Micrococcus luteus JCM 1464, Aspergillus niger ATCC 9642, Streptomyces murinus JCM 4333 등 5종의 세균과 진균에 대해 2.5 ${\mu}g$/mL에서 50 ${\mu}g$/mL 범위의 비교적 강한 항균력을 나타내었다. 본 실험을 통하여 얻은 결과는 분리균주의 유용성과 앞으로 추가적인 정제, 물질동정 실험을 통하여 새로운 항생물질을 탐색하는 기초를 제공할 수 있을 것으로 판단된다.

동아시아지역의 CMAQ 대류권 오존 모의에 화학적 측면 경계조건이 미치는 효과 (The Effect of the Chemical Lateral Boundary Conditions on CMAQ Simulations of Tropospheric Ozone for East Asia)

  • 홍성철;이재범;최진영;문경정;이현주;홍유덕;이석조;송창근
    • 한국대기환경학회지
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    • 제28권5호
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    • pp.581-594
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    • 2012
  • The goal of this study is to investigate the effects of the chemical lateral boundary conditions (CLBCs) on Community Multi-scale Air Quality (CMAQ) simulations of tropospheric ozone for East Asia. We developed linking tool to produce CLBCs of CMAQ from Goddard Earth Observing System-Chemistry (GEOS-Chem) as a global chemistry model. We examined two CLBCs: the fixed CLBC in CMAQ (CLBC-CMAQ) and the CLBC from GEOS-Chem (CLBC-GEOS). The ozone fields by CMAQ simulation with these two CLBCs were compared to Tropospheric Emission Spectrometer (TES) satellite data, ozonesonde and surface measurements for May and August in 2008. The results with CLBC-GOES showed a better tropospheric ozone prediction than that with CLBC-CMAQ. The CLBC-GEOS simulation led to the increase in tropospheric ozone concentrations throughout the model domain, due to be influenced high ozone concentrations of upper troposphere and near inflow western and northern boundaries. Statistical evaluations also showed that the CLBC-GEOS case had better results of both the index of Agreement (IOA) and mean normalized bias. In the case of IOA, the CLBC-GEOS simulation was improved about 0.3 compared to CLBC-CMAQ due to the better predictions for high ozone concentrations in upper troposphere.

Association of SNP Haplotypes at the Myostatin Gene with Muscular Hypertrophy in Sheep

  • Gan, S.Q.;Du, Z.;Liu, S.R.;Yang, Y.L.;Shen, M.;Wang, X.H.;Yin, J.L.;Hu, X.X.;Fei, J.;Fan, J.J.;Wang, J.H.;He, Q.H.;Zhang, Y.S.;Li, N.
    • Asian-Australasian Journal of Animal Sciences
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    • 제21권7호
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    • pp.928-935
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    • 2008
  • The myostatin gene of seven important meat (Beltex (Australia), Beltex$\times$Huyang (F1), Meat and Multi-Prolific Chinese Merino Fine Wool, Meat Chinese Merino Fine Wool and Dorper (South Africa)) and non-meat (Huyang and Kazak) sheep breeds was analyzed to study the genetic basis of muscular hypertrophy (double muscling) phenotype in sheep. SNPs, four in regulatory regions and several in the introns in the myostatin gene, were identified, and the former four SNPs were used for further studies. Twelve haplotypes were predicted by PHASE program, of which four main haplotypes (1, 3, 7, 9) were present in 90% of the 364 sheep in the study. Haplotypes 1-4 were mainly present in meat breeds while haplotypes 7 and 9 dominated the non-meat breeds. The association between haplotypes and average daily gain (ADG) was analyzed among 116 sheep with production data, Haplo2 (CGAA) and Haplo8 (TGAA) were identified to have significant (p<0.05) effect on ADG by the model (JMP5.1 software) taking into account the effects of breed, family background, haplotype, birth weight and sex. ADG of these haplotype groups also correlated well (r = 0.82) with hypertrophic phenotype scores. In conclusion, the mutations -956 (T$\rightarrow$C), -41 (C$\rightarrow$A) and 6223 (G$\rightarrow$A) involved in Haplo2 and 8 may be associated with the double-muscling trait by influencing myostatin function and be suitable markers in selecting meat sheep.

Genetic and Economic Analysis for the Relationship between Udder Health and Milk Production Traits in Friesian Cows

  • El-Awady, H.G.;Oudah, E.Z.M.
    • Asian-Australasian Journal of Animal Sciences
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    • 제24권11호
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    • pp.1514-1524
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    • 2011
  • A total of 4,752 monthly lactation records of Friesian cows during the period from 2000 to 2005 were used to estimate genetic parameters and to determine the effect of udder health on milk production traits. Three milk production traits were studied: 305-day milk yield (305-dMY), 305-day fat yield (305-dFY) and 305-day protein yield (305-dPY). Four udder health traits were studied: somatic cell count (SCC), mastitis (MAST), udder health status (UDHS) with 10 categories and udder quarter infection (UDQI) with 7 categories. Mixed model least square analysis was used to estimate the fixed effects of month and year of calving and parity (P) on different studied traits. Sire and dam within sire were included in the model as random effects. Data were analyzed using Multi-trait Derivative Free Restricted Maximum Likelihood methodology (MTDFREML) to estimate genetic parameters. Unadjusted means of 305-dMY, 305-dFY, 305-dPY and SCC were 3,936, 121, 90 kg and 453,000 cells/ml, respectively. Increasing SCC from 300,000 to 2,000,000 cells/ml increased UDQI from 5.51 to 23.2%. Losses in monthly and lactationally milk yields per cow ranged from 17 to 93 and from 135 to 991 kg, respectively. The corresponding losses in monthly and lactationally milk yields return per cow at the same level of SCC ranged from 29.8 to 163 and from 236 to 1,734 Egyptian pounds, respectively. Heritability estimates of 305-dMY, 305-dFY, 305-dPY, SCC, MAST, UDHS, UDQI were 0.31${\pm}$0.4, 0.33${\pm}$0.03, 0.35${\pm}$0.05, 0.23${\pm}$0.02, 0.14${\pm}$0.02, 0.13${\pm}$0.03, and 0.09${\pm}$0.01, respectively. All milk production traits showed slightly unfavorable negative phenotypic and genetic correlations with SCC, MAST, UDHS and UDQI. There were positive and high genetic correlations between SCC and each of MAST (0.85${\pm}$0.7), UDHS (0.87${\pm}$0.10) and UDQI (0.77${\pm}$0.06) and between MAST and each of UDHS (0.91${\pm}$0.11) and UDQI (0.83${\pm}$0.07). It could be concluded that the economic losses from mastitis and high SCC are considerable. The high genetic correlation between SCC and clinical mastitis (CM) suggest that the selection for lower SCC would help to reduce or eliminate the undesirable correlated responses of clinical mastitis associated with selection for increasing milk yield. Additionally, it is recommended also that if direct information on under health traits is not available, measures of SCC can be inclusion in a selection criteria to improve the income from dairy cows.

가계 재무건전성이 주택투자수요에 미치는 영향에 관한 연구 (A Study on the Financial Strength of Households on House Investment Demand)

  • 노상윤;윤보현;최영민
    • 유통과학연구
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    • 제12권4호
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    • pp.31-39
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    • 2014
  • Purpose - This study investigates the following two issues. First, we attempt to find the important determinants of housing investment and to identify their significance rank using survey panel data. Recently, the expansion of global uncertainty in the real estate market has directly and indirectly influenced the Korean housing market; households demonstrate a sensitive reaction to changes in that market. Therefore, this study aims to draw conclusions from understanding how the impact of financial strength of the household is related to house investment. Second, we attempt to verify the effectiveness of diverse indices of financial strength such as DTI, LTV, and PIR as measures to monitor the housing market. In the continuous housing market recession after the global crisis, the government places top priority on residence stability. However, the government still imposes forceful restraints on indices of financial strength. We believe this study verifies the utility of these regulations when used in the housing market. Research design, data, and methodology - The data source for this study is the "National Survey of Tax and Benefit" from 2007 (1st) to 2011 (5th) by the Korea Institute of Public Finance. Based on this survey data, we use panel data of 3,838 households that have been surveyed continuously for 5 years. We sort the base variables according to relevance of house investment criteria using the decision tree model (DTM), which is the standard decision-making model for data-mining techniques. The DTM method is known as a powerful methodology to identify contributory variables for predictive power. In addition, we analyze how important explanatory variables and the financial strength index of households affect housing investment with the binary logistic multi-regressive model. Based on the analyses, we conclude that the financial strength index has a significant role in house investment demand. Results - The results of this research are as follows: 1) The determinants of housing investment are age, consumption expenditures, income, total assets, rent deposit, housing price, habits satisfaction, housing scale, number of household members, and debt related to housing. 2) The impact power of these determinants has changed more or less annually due to economic situations and housing market conditions. The level of consumption expenditure and income are the main determinants before 2009; however, the determinants of housing investment changed to indices of the financial strength of households, i.e., DTI, LTV, and PIR, after 2009. 3) Most of all, since 2009, housing loans has been a more important variable than the level of consumption in making housing market decisions. Conclusions - The results of this research show that sound financing of households has a stronger effect on housing investment than reduced consumption expenditures. At the same time, the key indices that must be monitored by the government under economic emergency conditions differ from those requiring monitoring under normal market conditions; therefore, political indices to encourage and promote the housing market must be divided based on market conditions.

MJF 3D 프린팅 기반 폴리아미드-12 소재의 건축적 활용을 위한 기계적 특성 실험에 관한 연구 - 출력 방향에 따른 인장 특성 변화를 중심으로 - (A Study on the Mechanical Properties Experiment for Architectural Application of Polyamide-12 MJF 3D Printing Material - Focusing on the Change in Tensile Properties According to the 3D Printing Orientation -)

  • 박상재;유승규;김문환;김재준
    • 한국건설관리학회논문집
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    • 제21권6호
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    • pp.95-102
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    • 2020
  • 3D 프린팅 기술은 4차 산업 혁명의 도래와 함께 다양한 산업 분야에서 주목받고 있다. 특히 정밀한 부품을 제작하는 기계, 항공 등의 산업에서 그 활용 사례가 증가하고 있으며 건축 산업 역시 3D 프린팅 기술을 활용한 사례가 늘어나고 있는 추세이다. 현재 다양한 3D 프린팅용 소재가 개발 및 활용되고 잇지만, 3D 프린팅 제조는 사출 및 성형과 같은 기존 제조 방법과 비교하였을 때 제품의 기계적 특성이 달라질 가능성이 있다는 문제점이 있다. 본 논문은 3D 프린팅용 플라스틱 소재 중 널리 활용되고 있는 PA12 소재의 제품 제작 시 출력 방향이 제품의 기계적 특성에 미치는 영향을 검증하고 소재에 대한 이해를 확장시켜 건축 부자재 및 구조재로서의 활용 등의 실무적인 활용에 대한 기초 자료를 제공한다. 실험은 출력 방향의 영향을 확인하기 위해 0°, 30°, 45°, 60°, 90° 방향의 제품을 출력하였으며 인장 강도 실험을 통하여 인장 강도, 항복 강도, 연신율을 비교하였다. 실험 결과, 0° 방향으로 출력한 제품이 전반적으로 가장 낮은 강도와 연신율을 보였으며 45° 방향으로 출력한 제품이 가장 높은 수치를 보였다. 또한 전반적으로 0°부터 45° 사이에서는 인장강도와 항복 강도가 상승하였으며, 45°부터 90° 에서는 다소 감소하는 경향을 보였다.

결혼이주여성의 가족 회복력 모형검증 (Verification Effect of Family Resilience Model of married immigrant women)

  • 오재우;박인숙
    • 디지털융복합연구
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    • 제11권5호
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    • pp.355-370
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    • 2013
  • 본 연구는 결혼이주여성을 대상으로 회복력 요인의 관계양상 및 영향력을 확인하고 가족적응을 증진시키는데 유용한 간호실무의 기초자료를 제공하고자 시도되었다. 연구대상은 한국에서 거주한지 1년 이상 된 대전 외곽의 도 농 복합지역 및 충남 지역에 있는 결혼이주여성이 대상이었다. 자료수집기간은 2012년 2월부터 2012년 7월까지 시행하였으며, 최종 216부를 자료의 분석 대상으로 하였다. 수집된 자료는 SPSS, LISREL을 이용하여 빈도분석, 백분율, ANOVA, t-test, 상관관계 분석을 하였고, 가설검정은 경로분석을 하였다. 가설모형의 전반적 지수는 ${\chi}^2$= .06(p= .812), df=1, ${\chi}^2$(df)=.06, GFI=1.0, AGFI= 1.0, SRMR=.002, NFI= 1.0, NNFI=1.0, RMSEA=0.000, CN=266으로 좋은 부합도를 보였다. 모형에서 제시된 가설검증 결과를 보면 가족적응에 영향을 미치는 변수는 가족스트레스와 양육스트레스로 나타났고, 사회적 지지 및 가족강인성, 문제해결 의사사통, 문제해결 대처는 가족적응에 영향을 미치지 못하였다. 이런 연구결과를 바탕으로 위기상황에 놓여있는 결혼이주여성의 가족의 적응을 돕는 간호중재는 스트레스 상황에 대해 결혼이주여성을 중심으로 긍정적인 관점을 가지도록 돕고, 가족 관계 내에서 발생하는 스트레스와 양육스트레스를 감소시킬 수 있는 프로그램을 개발하여 활용하는 중재가 수행되어야 할 것으로 생각된다.