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Effect of Temperature on T1 and T2 Relaxation Time in 3.0T MRI (3.0T MRI에서 온도변화가 T1 및 T2 이완시간에 미치는 영향)

  • Kim, Ho-Hyun;Kwon, Soon-Yong;Lim, Woo-Teak;Kang, Chung-Hwan;Kim, Kyung-Soo;Kim, Soon-Bae;Baek, Moon-Young
    • Korean Journal of Digital Imaging in Medicine
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    • v.15 no.2
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    • pp.63-68
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    • 2013
  • Purpose : The relaxation times of tissue in MRI depend on strength of magnetic field, morphology of nuclear, viscosity, size of molecules and temperature. This study intended to analyze quantitatively that materials' temperatures have effects on T1 and T2 relaxation times without changing of other conditions. Materials and Methods : The equipment was used MAGNETOM SKYRA of 3.0T(SIEMENS, Erlagen, Germany), 32 channel spine coil and Gd-DTPA water concentration phantom. To find out T1 relaxation time, Inversion Recovery Spin Echo sequences were used at 50, 400, 1100, 2500 ms of TI. To find out T2 relaxation time, Multi Echo Spin Echo sequences were used at 30, 60, 90, 120, 150, 180, 210, 240, 270 ms of TE. This experiment was scanned with 5 steps from 25 to $45^{\circ}C$. next, using MRmap(Messroghli, BMC Medical Imaging, 2012) T1 and T2 relaxation times were mapped. on the Piview STAR v5.0(Infinitt, Seoul, Korea) 5 steps were measured as the same ROI, and then mean values were calculated. Correlation between the temperatures and relaxation times were analyzed by SPSS(version 17.0, Chicago, IL, USA). Results : According to increase of temperatures, T1 relaxation times were $214.39{\pm}0.25$, $236.02{\pm}0.87$, $267.47{\pm}0.48$, $299.44{\pm}0.64$, $330.19{\pm}1.72$ ms. T2 relaxation times were $180.17{\pm}0.27$, $197.17{\pm}0.44$, $217.92{\pm}0.39$, $239.89{\pm}0.53$, $257.40{\pm}1.77$ ms. With the correlation analysis, the correlation coefficients of T1 and T2 relaxation times were statistically significant at 0.998 and 0.999 (p< 0.05). Conclusion : T1 and T2 relaxation times are increased as temperature of tissue goes up. In conclusion, we suggest to recognize errors of relaxation time caused local temperature's differences, and consider external factors as well in the quantitative analysis of relaxation time or clinical tests.

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A Study on the Relationship between Job Stress and Socio-Psychological stress of firefighter (소방공무원의 직무스트레스와 사회심리적 스트레스와의 연관성에 관한 연구)

  • Kang, Byung-Woo
    • The Korean Journal of Emergency Medical Services
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    • v.13 no.1
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    • pp.35-48
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    • 2009
  • Purpose: Firefighters were subjected to be exposed to 24-hour shiftwork and high level of job stress, but there is little study of fire fighters about between Job Stress and Psychological stress in Korea. This study was performed to evaluate job stress of fire fighters grouped by different job types and analyze the health effect of job stress by using a PWI-SF(Psycho-social Well-being Index, Short Form). Methods : This study was to measure the degree of job stress and socio-psychological stress of firefighters working at 119 safety center and analyze the relationship between job stress and mental health, through self-administered questionnaire survey on 918 fire fighters working at fire department located in Korea, during October in 2008. Question items of the questionnaire consist of general characteristics, job stress, and socio-psychological stress. Job Stress Measurement Scale for Koreans was used to measure job stress, while PWI-SF used for socio-psychological stress. Collected data was analyzed through frequency analysis, ${\chi}^2$ test, one-way ANOVA, correlation analysis, multi-regression analysis using a statistic program, SPSS/10.0 Ver for Windows, and statistical significance level was 0.05. Result : Accordingly, this paper is written for the purpose of scrutinizing the reason of 119 rescuers' job stress and Socio-Psychological stress. This thesis tries to analyze a problem and provide contents through many variables concerned and theoretical investigation with the actual research of questionnaire. The results of the study are summarized as follows : Fire fighters feel relatively high stressful in their performance. Job stress, organizational commitment and burnout did not have been influence upon by individual cases such as economic condition, regular exercise etc. Finally, as a result of step by step regression analysis, the variable that can explain Socio-Psychological stress the best was negative emotion scale(NE). Conclusions : It is necessary to conduct repeated studies in the future, since the study implied that there was a contrary relationship between job stress and socio-psychological stress. In order to reduce job stress and maintain better mental health, it is more important than anything else to help firefighters have willingness and efforts to sustain a healthy life, so the development of various programs and education to raise their awareness should be implemented.

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The Study of a Development Plan of the Industrial Security Expert System (산업보안관리사 자격제도 발전 방안에 대한 고찰)

  • Cho, Yong-Sun
    • Korean Security Journal
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    • no.40
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    • pp.175-207
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    • 2014
  • This paper focuses on the study of a development direction of the industrial security Expert system. First of all, in order to manage Industrial security system, we need to have law, criminology, business and engineering professionals as well as IT experts, which are the multi-dimensional convergence professionals. Secondly, industrial organizations need to have workforce who can perform security strategy; security plan; security training; security services; or security system management and operations. Industrial security certification system can contribute to cultivate above mentioned professional workforce. Currently Industrial Security Expert(ISE) is a private qualification. However, the author argued that it have to be changed to national qualification. In addition, it is necessary that the system should be given credibility with verifying the personnel whether they are proper or not in the their field. In terms of quality innovation, it is also necessary that distinguish the levels of utilization of rating system of the industrial security coordinator through a long-term examination. With respect to grading criteria, we could consider the requirements as following: whether they must hold the degree of the industrial security-related areas of undergraduate or postgraduate (or to be); what or how many industrial security-related courses they should complete through a credit bank system. If the plan of completing certain industrial security-related credits simply through the credit bank system, without establishing a new industrial security-related department, has established, then industrial security study would be spreaded and advanced. For private certification holders, the problem of the qualification succeeding process is important matter. Additionally, it is necessary to introduce the certifying system of ISMS(Industrial Security Management System) which is a specialized system for protecting industrial technology. To sum up, when the industrial security management system links the industrial security management certification, industrial security would realize in the companies and research institutions dealing with national key technology. Then, a group synergy effect would occurs.

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Isolation and Identification of a Streptomyces sp. that Produces Antibiotics Against Multidrug - Resistant Acinetobacter baumannii (다제내성 Acinetobacter baumannii의 생장을 억제하는 항생물질을 생산하는 방선균의 분리.동정 및 항균효과)

  • Rhee, Ki-Hyeong
    • Microbiology and Biotechnology Letters
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    • v.39 no.1
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    • pp.37-42
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    • 2011
  • I isolated the actinomycete strain KH223 from soil samples collected from the Kye Ryong mountain area. This strain is antagonistic to the multidrug-resistant Acinetobacter baumannii. KH223 was confirmed as belonging to the genus Streptomyces based on the scanning electronmicroscopy(SEM) observations of the diaminopimelicacid(DAP) type and morphological and physiological characteristics. Comparison of the 16S rDNA nucleotide sequences revealed that KH223 has a relationship with Streptomyces galbus. Production of antibiotics by KH223 was most favorable when cultured on a glucose, polypeptone, and yeast extract(PY) medium for 6 days at 27$^{\circ}C$. The supernatant was found to exhibit an antimicrobial effect on various kinds of bacteria and fungi. Particularly, butanol and ethylacetate extracts of KH223 and cyclo(trp-trp) exhibited significant activity against A. baumannii at concentration ranges of 0.8-12.5 ${\mu}g$/mL, 5.0-25 ${\mu}g$/mL and 12.5${\rightarrow}$100 ${\mu}g$/mL, respectively. Moreover, in contrast to cyclo(trp-trp) had shown to activity against Micrococcus luteus JCM 1464 at the concentration of 12.5 ${\mu}g$/mL, the butanol extract of KH223 showed significant activity against Bacillus subtilis IAM 1069 and Micrococcus luteus JCM 1464 at the concentration of 0.4 and 0.8 ${\mu}g$/mL, respectively. These results suggest that KH223 may have a great potential in the production of new antibiotics to combat multidrug-resistant pathogens and further studies may be warranted for the same.

The Effect of the Chemical Lateral Boundary Conditions on CMAQ Simulations of Tropospheric Ozone for East Asia (동아시아지역의 CMAQ 대류권 오존 모의에 화학적 측면 경계조건이 미치는 효과)

  • Hong, Sung-Chul;Lee, Jae-Bum;Choi, Jin-Young;Moon, Kyung-Jung;Lee, Hyun-Ju;Hong, You-Deog;Lee, Suk-Jo;Song, Chang-Keun
    • Journal of Korean Society for Atmospheric Environment
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    • v.28 no.5
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    • pp.581-594
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    • 2012
  • The goal of this study is to investigate the effects of the chemical lateral boundary conditions (CLBCs) on Community Multi-scale Air Quality (CMAQ) simulations of tropospheric ozone for East Asia. We developed linking tool to produce CLBCs of CMAQ from Goddard Earth Observing System-Chemistry (GEOS-Chem) as a global chemistry model. We examined two CLBCs: the fixed CLBC in CMAQ (CLBC-CMAQ) and the CLBC from GEOS-Chem (CLBC-GEOS). The ozone fields by CMAQ simulation with these two CLBCs were compared to Tropospheric Emission Spectrometer (TES) satellite data, ozonesonde and surface measurements for May and August in 2008. The results with CLBC-GOES showed a better tropospheric ozone prediction than that with CLBC-CMAQ. The CLBC-GEOS simulation led to the increase in tropospheric ozone concentrations throughout the model domain, due to be influenced high ozone concentrations of upper troposphere and near inflow western and northern boundaries. Statistical evaluations also showed that the CLBC-GEOS case had better results of both the index of Agreement (IOA) and mean normalized bias. In the case of IOA, the CLBC-GEOS simulation was improved about 0.3 compared to CLBC-CMAQ due to the better predictions for high ozone concentrations in upper troposphere.

Association of SNP Haplotypes at the Myostatin Gene with Muscular Hypertrophy in Sheep

  • Gan, S.Q.;Du, Z.;Liu, S.R.;Yang, Y.L.;Shen, M.;Wang, X.H.;Yin, J.L.;Hu, X.X.;Fei, J.;Fan, J.J.;Wang, J.H.;He, Q.H.;Zhang, Y.S.;Li, N.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.7
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    • pp.928-935
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    • 2008
  • The myostatin gene of seven important meat (Beltex (Australia), Beltex$\times$Huyang (F1), Meat and Multi-Prolific Chinese Merino Fine Wool, Meat Chinese Merino Fine Wool and Dorper (South Africa)) and non-meat (Huyang and Kazak) sheep breeds was analyzed to study the genetic basis of muscular hypertrophy (double muscling) phenotype in sheep. SNPs, four in regulatory regions and several in the introns in the myostatin gene, were identified, and the former four SNPs were used for further studies. Twelve haplotypes were predicted by PHASE program, of which four main haplotypes (1, 3, 7, 9) were present in 90% of the 364 sheep in the study. Haplotypes 1-4 were mainly present in meat breeds while haplotypes 7 and 9 dominated the non-meat breeds. The association between haplotypes and average daily gain (ADG) was analyzed among 116 sheep with production data, Haplo2 (CGAA) and Haplo8 (TGAA) were identified to have significant (p<0.05) effect on ADG by the model (JMP5.1 software) taking into account the effects of breed, family background, haplotype, birth weight and sex. ADG of these haplotype groups also correlated well (r = 0.82) with hypertrophic phenotype scores. In conclusion, the mutations -956 (T$\rightarrow$C), -41 (C$\rightarrow$A) and 6223 (G$\rightarrow$A) involved in Haplo2 and 8 may be associated with the double-muscling trait by influencing myostatin function and be suitable markers in selecting meat sheep.

Genetic and Economic Analysis for the Relationship between Udder Health and Milk Production Traits in Friesian Cows

  • El-Awady, H.G.;Oudah, E.Z.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.11
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    • pp.1514-1524
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    • 2011
  • A total of 4,752 monthly lactation records of Friesian cows during the period from 2000 to 2005 were used to estimate genetic parameters and to determine the effect of udder health on milk production traits. Three milk production traits were studied: 305-day milk yield (305-dMY), 305-day fat yield (305-dFY) and 305-day protein yield (305-dPY). Four udder health traits were studied: somatic cell count (SCC), mastitis (MAST), udder health status (UDHS) with 10 categories and udder quarter infection (UDQI) with 7 categories. Mixed model least square analysis was used to estimate the fixed effects of month and year of calving and parity (P) on different studied traits. Sire and dam within sire were included in the model as random effects. Data were analyzed using Multi-trait Derivative Free Restricted Maximum Likelihood methodology (MTDFREML) to estimate genetic parameters. Unadjusted means of 305-dMY, 305-dFY, 305-dPY and SCC were 3,936, 121, 90 kg and 453,000 cells/ml, respectively. Increasing SCC from 300,000 to 2,000,000 cells/ml increased UDQI from 5.51 to 23.2%. Losses in monthly and lactationally milk yields per cow ranged from 17 to 93 and from 135 to 991 kg, respectively. The corresponding losses in monthly and lactationally milk yields return per cow at the same level of SCC ranged from 29.8 to 163 and from 236 to 1,734 Egyptian pounds, respectively. Heritability estimates of 305-dMY, 305-dFY, 305-dPY, SCC, MAST, UDHS, UDQI were 0.31${\pm}$0.4, 0.33${\pm}$0.03, 0.35${\pm}$0.05, 0.23${\pm}$0.02, 0.14${\pm}$0.02, 0.13${\pm}$0.03, and 0.09${\pm}$0.01, respectively. All milk production traits showed slightly unfavorable negative phenotypic and genetic correlations with SCC, MAST, UDHS and UDQI. There were positive and high genetic correlations between SCC and each of MAST (0.85${\pm}$0.7), UDHS (0.87${\pm}$0.10) and UDQI (0.77${\pm}$0.06) and between MAST and each of UDHS (0.91${\pm}$0.11) and UDQI (0.83${\pm}$0.07). It could be concluded that the economic losses from mastitis and high SCC are considerable. The high genetic correlation between SCC and clinical mastitis (CM) suggest that the selection for lower SCC would help to reduce or eliminate the undesirable correlated responses of clinical mastitis associated with selection for increasing milk yield. Additionally, it is recommended also that if direct information on under health traits is not available, measures of SCC can be inclusion in a selection criteria to improve the income from dairy cows.

A Study on the Financial Strength of Households on House Investment Demand (가계 재무건전성이 주택투자수요에 미치는 영향에 관한 연구)

  • Rho, Sang-Youn;Yoon, Bo-Hyun;Choi, Young-Min
    • Journal of Distribution Science
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    • v.12 no.4
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    • pp.31-39
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    • 2014
  • Purpose - This study investigates the following two issues. First, we attempt to find the important determinants of housing investment and to identify their significance rank using survey panel data. Recently, the expansion of global uncertainty in the real estate market has directly and indirectly influenced the Korean housing market; households demonstrate a sensitive reaction to changes in that market. Therefore, this study aims to draw conclusions from understanding how the impact of financial strength of the household is related to house investment. Second, we attempt to verify the effectiveness of diverse indices of financial strength such as DTI, LTV, and PIR as measures to monitor the housing market. In the continuous housing market recession after the global crisis, the government places top priority on residence stability. However, the government still imposes forceful restraints on indices of financial strength. We believe this study verifies the utility of these regulations when used in the housing market. Research design, data, and methodology - The data source for this study is the "National Survey of Tax and Benefit" from 2007 (1st) to 2011 (5th) by the Korea Institute of Public Finance. Based on this survey data, we use panel data of 3,838 households that have been surveyed continuously for 5 years. We sort the base variables according to relevance of house investment criteria using the decision tree model (DTM), which is the standard decision-making model for data-mining techniques. The DTM method is known as a powerful methodology to identify contributory variables for predictive power. In addition, we analyze how important explanatory variables and the financial strength index of households affect housing investment with the binary logistic multi-regressive model. Based on the analyses, we conclude that the financial strength index has a significant role in house investment demand. Results - The results of this research are as follows: 1) The determinants of housing investment are age, consumption expenditures, income, total assets, rent deposit, housing price, habits satisfaction, housing scale, number of household members, and debt related to housing. 2) The impact power of these determinants has changed more or less annually due to economic situations and housing market conditions. The level of consumption expenditure and income are the main determinants before 2009; however, the determinants of housing investment changed to indices of the financial strength of households, i.e., DTI, LTV, and PIR, after 2009. 3) Most of all, since 2009, housing loans has been a more important variable than the level of consumption in making housing market decisions. Conclusions - The results of this research show that sound financing of households has a stronger effect on housing investment than reduced consumption expenditures. At the same time, the key indices that must be monitored by the government under economic emergency conditions differ from those requiring monitoring under normal market conditions; therefore, political indices to encourage and promote the housing market must be divided based on market conditions.

A Study on the Mechanical Properties Experiment for Architectural Application of Polyamide-12 MJF 3D Printing Material - Focusing on the Change in Tensile Properties According to the 3D Printing Orientation - (MJF 3D 프린팅 기반 폴리아미드-12 소재의 건축적 활용을 위한 기계적 특성 실험에 관한 연구 - 출력 방향에 따른 인장 특성 변화를 중심으로 -)

  • Park, Sangjae;Yoo, Seungkyu;Kim, Munhwan;Kim, Jaejun
    • Korean Journal of Construction Engineering and Management
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    • v.21 no.6
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    • pp.95-102
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    • 2020
  • The number of use cases in machinery, aviation, and other industries that manufacture precise parts is increasing, and the construction industry is also increasingly using 3D printing technology. Although various materials for 3D printing are currently being developed and utilized, 3D printing manufacturing has a problem that the mechanical properties of the product may change when compared with conventional manufacturing methods such as injection and molding. This paper verifies the effect of the printing orientation on the mechanical properties of the product in the manufacture of PA12 material and providing basic data on the practical use of the materials as building subsidiary materials and structural materials. The results of the experiment showed that the product printed in the orientation of 0° showed the lowest overall strength and elongation rate, and the product printed in the orientation of 45° showed the highest figure. Overall, tensile strength and yield strength increased between 0° and 45°, and tended to decrease somewhat at 45° to 90°.

Verification Effect of Family Resilience Model of married immigrant women (결혼이주여성의 가족 회복력 모형검증)

  • Oh, Jaewoo;Park, Insook
    • Journal of Digital Convergence
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    • v.11 no.5
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    • pp.355-370
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    • 2013
  • This study was aimed at the married immigrant women and was attempted to provide the basic data of the nursing practice useful in identifying the relationship aspects and the influence of resilience factor and promoting the family adaptation. This study was conducted for the married immigrant women who were located in urban-rural complex area around Daejeon city and in Chungnam region, and the multi-cultural families supporting program of community welfare halls among those who had resided over 1 year in Korea. The data was collected from Feb, 2012 to July, 2012 and in the end, 216 questionnaires were made the subjects of data analysis. For the collected data, frequency analysis, percentage, ANOVA, t-test and correlation analysis were conducted using SPSS, LISREL. The overall index of hypothesis model showed a good congruence like ${\chi}^2$ = .06 (p= .812), df=1, ${\chi}^2$(df)=.06, GFI=1.0, AGFI= 1.0, SRMR=.002, NFI= 1.0, NNFI=1.0, RMSEA=0.000, CN=266. Looking at the results of hypothesis testing suggested by the model, the variables which affected the family adaptation were family stress and parenting stress, while social support, family hardness, problem solving communication, and problem solving coping didn't affect the family adaptation. It is considered that based on the results of this study, nursing intervention which helps the family adaptation of the married immigrant women who are in a crisis situation must be done with a program which can help them have a positive view on the stress situation and reduce the stress happening in the family relationship and parenting.