• Title/Summary/Keyword: Motor system

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DENTAL TREATMENT IN A PATIENT WITH METACHROMATIC LEUKODYSTROPHY UNDER GENERAL ANESTHESIA : A CASE REPORT (이염성 백질 이영양증 환아의 치아우식 치료 증례 보고)

  • Ryu, Jiyeon;Shin, Teo Jeon;Hyun, Hong-Keun;Kim, Young Jae;Kim, Jung-Wook;Jang, Ki-Taeg;Kim, Chong-Chul;Lee, Sang-Hoon
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.12 no.2
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    • pp.96-100
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    • 2016
  • Metachromatic leukodystrophy (MLD) is a progressive and degenerative neurological disease caused by a deficiency of the catabolic enzyme arylsulfatase A. Deficiency of arylsulfatase A results in accumulation of sulfatide in the white matter of the peripheral and central nervous system and it occurs demyelination as a result. The patient gradually goes through mental and motor failure. General symptoms of MLD include gait disturbance, mental deterioration, muscle rigidity and impaired swallowing. Inheritance of the disease is autosomal recessive. We report a dental caries treatment of a 3-year old boy with MLD. The patient underwent hematopoietic stem cell transplantation (HSCT) to slow the progression of the disease. He was suffered from difficulties of mastication and swallowing from the degenerative neurological symptom. He was ingesting food by both oral feeding and tubal feeding after he took percutaneous endoscopic gastrostomy (PEG). The cause of multiple caries was mainly presumed as patient's prolonged time of meal. The treatment was performed under general anesthesia considering patient's incompliance. Severely affected lower primary molars were treated with pulp treatment and restored with stainless steel crown. Others were restored with composite resin. There were no postoperative complications. MLD is life threatening progressive disease and also has an impact on unfavorable condition for oral health. Routine home oral care and periodic professional dental care should be emphasized to the caregiver of patient considering the susceptibility of dental caries. Not only the medical care, but periodic dental office visit would benefit the quality of life of the patient.

Localization of the Neurons Projecting to the Gallbladder Meridian (족소양담경(足少陽膽經)에서 투사(投射)되는 신경원(神經元)의 표지부위(標識部位)에 대한 연구(硏究))

  • Ryuk Sang-Won;Lee Kwang-Gyu;Lee Sang-Ryoung;Kim Jum-Young;Lee Chang-Hyun;Lee Bong-Hee
    • Korean Journal of Acupuncture
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    • v.17 no.1
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    • pp.101-121
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    • 2000
  • The purpose of this morphological studies was to investigate the relation to the meridian, acupoint and nerve. The common locations of the spinal cord and brain projecting to the the gallbladder, GB34 and common peroneal nerve were observed following injection of transsynaptic neurotropic virus, pseudorabies virus(PRV), into the gallbladder, GB34 and common peroneal nerve of the rabbit. After survival times of 96 hours following injection of PRV, the thirty rabbits were perfused, and their spinal cord and brain were frozen sectioned($30{\mu}m$). These sections were stained by PRV immunohistochemical staining method, and observed with light microscope. The results were as follows: 1. In spinal cord, PRV labeled neurons projecting to the gallbladder, GB34 and common peroneal nerve were founded in thoracic, lumbar and sacral spinal segments. Densely labeled areas of each spinal cord segment were founded in lamina V, VII, X, intermediolateral nucleus and dorsal nucleus. 2. In medulla oblongata, The PRV labeled neurons projecting to the gallbladder, GB34 and common peroneal nerve were founded in the A1 noradrenalin cells/C1 adrenalin cells/caudoventrolateral reticular nucleus, rostroventrolateral reticular nucleus, medullary reticular nucleus, dorsal motor nucleus of vagus nerve, nucleus tractus solitarius, raphe obscurus nucleus, raphe pallidus nucleus, raphe magnus nucleus, gigantocellular nucleus, lateral paragigantocellular nucleus, principal sensory trigeminal nucleus and spinal trigeminal nucleus. 3. In Pons, PRV labeled neurons were parabrachial nucleus, Kolliker-Fuse nucleus and cochlear nucleus. 4. In midbrain, PRV labeled neurons were founded in central gray matter and substantia nigra. 5. In diencephalon, PRV labeled neurons were founded in lateral hypothalamic nucleus, suprachiasmatic nucleus and paraventricular hypothalamic nucleus. 6. In cerebral cortex, PRV labeled neuron were founded in hind limb area.This results suggest that PRV labeled common areas of the spinal cord projecting to the gallbladder, GB34 and common peroneal nerve may be first-order neurons related to the somatic sensory, viscero-somatic sensory and symapathetic preganglionic neurons, and PRV labeled common area of the brain may be first, second and third-order neurons response to the movement of smooth muscle in gallbladder and blood vessels.These PRV labeled neurons may be central autonomic center related to the integration and modulation of reflex control linked to the sensory system monitoring the internal environment, including both visceral sensation and various chemical and physical qualities of the bloodstream. The present morphological results provide that gallbladder meridian and acupoint may be related to the central autonomic pathways.

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Design of an Optimal Adaptive Filter for the Cancellation of M-wave in the EMG Controlled Functional Electrical Stimulation for Paralyzed Individuals (마비환자의 근전도제에기능적전기자극을 위한 M-wave 제거용 최적적응필터 설계)

  • Yeom Hojoon;Park Youngcheol;Lee Younghee;Yoon Youngro;Shin Taemin;Yoon Hyoungro
    • Journal of Biomedical Engineering Research
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    • v.25 no.6
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    • pp.479-487
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    • 2004
  • Biopotential signals have been used as command in systems using electrical stimulation of motor nerves to restore movement after an injury to the central nervous system (CNS). In order to use the voluntary EMG (electromyography) among the biopotentials as a control signal for the electrical stimulation of the same muscle for CNS injury patients, it is necessary to remove M-wave of having high magnitude from raw data. We designed an optimal filter for removing the M-wave and preserving the voluntary EMG and showed that the optimal filter is eigen filter. We also proved that the previous method using the prediction error filter(PEF) is a suboptimal filtering in the sense of preserving the voluntary EMG. On basis of the data obtained from a model for M-wave and voluntary EMG and from actual CNS injury patients, with false-positive rate analysis, the proposed adaptive filter showed a very promising performance in comparison with previous method.

The Study on the Standardization of the Maximum Acceleration of the Electric Multiple Unit through the Analysis of the Traction and the Adhesion Characteristics (견인력 및 점착력 특성 분석을 통한 전동차 최대 가속도 규격 선정에 관한 연구)

  • Kim, Jungtai;Kim, Moo Sun;Ko, Kyeongjun;Jang, Dong Uk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.11
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    • pp.7934-7940
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    • 2015
  • The raise of the acceleration can be one of possible methods to increase the scheduled speed of the metropolitan railway system. It is possible to raise the acceleration to the some point by increasing the traction power of the motor. However, there is a limit of the acceleration because the traction power over some level related to the adhesion causes a slip, which prevents from accomplishing the target acceleration. The running resistance is also an important factor to consider. Both the adhesion and the running resistance as well as the traction power vary according to the velocity. Therefore, the standardization of the acceleration needs the analysis of these factors as a function of velocity. In this study, we focus on the advanced urban transit unit(AUTS) for the standardization. We derive a novel equation of the adhesion suitable for the AUTS by investigation of the traction and adhesion equation as well as the experiment data. And finally we propose the standard of the acceleration based on this analysis.

The Development of a beam profile monitoring system for improving the beam output characteristics (빔 출력 특성 개선을 위한 빔 프로파일 모니터링 시스템 개발)

  • An, Young-jun;Hur, Min-goo;Yang, Seung-dae;Shin, Dae-seob;Lee, Dong-hoon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.11
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    • pp.2689-2696
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    • 2015
  • Radioactive isotopes which are manufactured using a cyclotron in a radioisotope used for radiation diagnosis is affected by the production yield according to size and shape of the beam and beam uniform degree from irradiated location when the proton beam investigated the target by cyclotron. Therefore, in this paper developed the BPM(Beam Profile Monitor) device capable of measuring the beam cross-section at the cyclotron beam line. It was configured so as to be able to remote control the BPM device in LabView and used the BPM program it was to be able to easily monitor and display to analyze the graph of two-dimensional graph and a three-dimensional beam distribution numerical information of the beam obtained while scanning the tungsten wire to the X and Y axis. The time it takes to measure the beam can be confirmed 37seconds when step motor driving speed was 2000pps. Through a beam readjusted based on the measured beam distribution information by optimizing the beam distribution it can be made to maximize the RI production yield and contribute supply stabilization.

Arm Swing Asymmetry and Effect of Auditory Cues on Amplitude in the Patients with Parkinson's Disease (파킨슨병 환자의 상지 스윙의 비대칭과 청각신호에 따른 보행 시 진폭에 미치는 영향)

  • Son, Ho-Hee;Kim, Eun-Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.1
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    • pp.344-350
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    • 2013
  • A recent study reporting significantly reduced symmetry in arm swing amplitude in early Parkinson's disease (PD), as measured during gait by auditory cues velocity, led to this investigation of arm swing symmetry and amplitude in PD. The subjects were 14 elderly patients diagnosed with PD. Patients were measured of three conditions performed in random order: slow, general, fast. The auditory cue velocity consisted of a metronome beat ${\pm}20%$ than the subject's general gait speed. Using a motion analysis measurement system, changes in kinematic variables were compared to arm swing analysis. PD groups showed a highly significant reduction of the arm swing amplitude on the more affected body side(MAS)(p<.05). Comparison between the auditory cues velocity, there was a significant increase arm swing amplitude in fast velocity gait than slow and general velocity gait(p<.05). We conclude that motion analysis during gait by auditory cues velocity allows reliable investigation of asymmetric arm movements in early PD patients which attenuate with ongoing disease. The measurement of limb kinematics during gait by auditory cues velocity can broaden our methodological line-up for the analysis of complex motor programs in movement disorders.

Measuring Quality of Life in Cerebral Palsy Children According to the Severity Using the Visual Analogue Scale, Time Trade-Off, and EQ-5D-Y Proxy (뇌성마비 환아 중증도별 시각화척도, 시간교환법, EQ-5D-Y Proxy를 이용한 삶의 질 측정)

  • Lee, Go-Eun;Kim, Nam Kwen;Yun, Young Ju;Wang, Hye Min;Kim, Jeong Hun;Lee, Dong Hyo
    • Journal of Oriental Neuropsychiatry
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    • v.28 no.2
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    • pp.49-59
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    • 2017
  • Objectives: To measure the quality of life in patients according to virtual cerebral palsy severity by using the Korean version of EQ-5D-Y proxy, Visual Analogue Scale (VAS), and Time Trade-Off method (TTO). Methods: The study was conducted in parents of children and adolescents aged 4 to 15 years in Seoul. We analyzed the difference in the utility value according to five levels of cerebral palsy severity in the Gross Motor Function Classification System (GMFCS) and test-retest reliability. Results: 1. There were significant differences in VAS, TTO, and EQ-5D-Y proxy according to the cerebral palsy severity (p<.001). 2. VAS was significantly different according to the respondent's visit to the medical institution, the presence of disease in the respondent, a visit to the child's medical institution, the age of the child, and the sex of the child. The value of TTO was significantly different according to the respondent's visit to the medical institution, respondent's sex, and the age of the child. Also, EQ-5D-Y proxy was significantly different according to the age of the child. 3. Intraclass correlation coefficient values were more than 0.6 for both VAS and TTO at all stages. But for the EQ-5D-Y proxy, the value was less than 0.6 at all stages. Conclusions: The quality of life assessment using EQ-5D-Y proxy showed significant differences in the severity of cerebral palsy. However, large-scale studies using EQ-5D-Y proxy are needed because of low test-retest reliability.

An Air Cleaning Efficiencies of Wet Air Cleaner in the Windowless Swine Fattening Stall in Summer (무창 비육돈사에서 습식공기정화기의 여름철 공기정화효율 분석)

  • Oh, I.H.;Lee, J.H.;Lee, K.H.;Lee, J.H.;Lee, D.S.;Eo, S.M.;Lee, M.L.
    • Journal of Animal Environmental Science
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    • v.12 no.3
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    • pp.133-140
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    • 2006
  • The climate of stall significantly influences on animal production ability. High concentration of ammonia gas, $CO_2$ and lots of dust are found in modern densely raising stall system, as results, they provide a negative influence on animal and farmer health, and production ability. Therefore, it is necessary to keep clean the inside air of stall to increase the productivity. An air cleaner of wet type, consisting of a fan, a motor, rotating discs, a dust collector, a water bowl, an ozone generator etc, has been developed to clean the stall air. The work principle is that the inside air is sucked through the fan, and the rotating discs make water into fineness spray and blow into the stall. The rest water flows down to the dust collector. In the present study, we measured the dust, ammonia gas, odor, temperature and humidity in a swine stall that were installed two wet air cleaners with 700 fattening swine with On-mode and Off-mode of wet air cleaners. The dust measure was divided into 3 categories, TSP, $PM_{10}$, and $PM_{2.5}$. In summer, the TSP in on-mode were maximum $0.259mg/m^3$ and minimum $0.128mg/m^3$, and the average was $0.195mg/m^3$. These are comparable to the data from Off-mode stall that maximum $0.308mg/m^3$, minimum $0.139mg/m^3$, and average $0.277mg/m^3$. However, $PM_{10}$ and $PM_{2.5}$ showed any significant differences between the tests. The concentrations of ammonia gas in Off-mode stall were maximum 13.8 ppm and minimum 5.9 ppm, and the average was 8.47 ppm. However in On-mode stall the ammonia gas concentrations were maximum 10.5 ppm and minimum 5.5 ppm, and the average was 7.63 ppm. The concentration of ammonia gas in On-mode was 10% in average lower than off-mode stall. Odor was measured by olfactometer. In the Off-mode stall, the odor unit were maximum 420 $Ou/m^3$ and minimum $300\;OU/m^3$, and the average was $367\;OU/m^3$, but in the On-mode stall the odor unit were maximum $330\;OU/m^3$ and minimum $210\;OU/m^3$, and the average was $253\;OU/m^3$. Odor removal efficiency was about 31% in On-mode stall.

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The Optomotor Response of Killifish and Yellowtail (송사리와 방어의 시각운동반응)

  • Jang, Choong-sik;Lee, Byoung-gee
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.19 no.1
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    • pp.17-24
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    • 1983
  • The authors carried out an experiment to find the optomotor response of killifish, Orizias latipes(TEMMINCK et SCHLEGEL) and Yellowtail, Seriola quinqueradiata (TEMMINCK et SCHLEGEL) according to the colors of the netting pattern on the visual screen and the revolving velocities of the visual screen. The experimental water tank was made of 0.5 cm thick transparent acryl in the cylindrical shape (100R$\times$42H cm). The water level in the tank was maintained 30cm high from the bottom. The colors of the netting pattern (mesh size: 19.1cm, width of netting twine: 1.5cm, hanging ratio: 84%) on the three visual screens were black, red and green respectively. The revolving velocities of the visual screen were controlled by pulley, bevel gear and variable speed motor in three steps; slow (15.0cm/sec), middle (37.4cm/sec) and high (62.9cm/sec). The fish was put into the water tank before each experiment and released in it for 30 minutes in order to acclimatize itself to the tank. The visual screen was revolved for 4 minutes per each experiment, at first the fish was released for 1 minute, and then the behavior of the fish was observed for 3 minutes. In the course of clockwise and counter clockwise experiments, 10 minutes-pause was given for the rest. The behavior of the fish was observed by video system, and rounding number and swimming speed of the fish were analysed. The results obtained are as follows: (1) Optomotor response rate of Killifish and yellowtail were 95% and 94% respectively. (2) Response of the fish according to the colors of the netting pattern on the three visual screens was best in black, and second in red and third in green. (3) Response of the fish according to the revolving velocities of the visual screen was best in high speed, and second in middle speed and third in slow speed.

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Remote Sensing of Atmospheric Trace Species using Multi Axis Differential Optical Absorption Spectroscopy (Multi Axis DOAS를 이용한 대기미량 물질 원격 측정)

  • Lee Chul-Kyu;Kim Young-Joon
    • Korean Journal of Remote Sensing
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    • v.22 no.2
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    • pp.141-151
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    • 2006
  • UV-visible absorption measurement techniques using several horizone viewing directions in addition to the traditional zenith-sky pointing have been recently developed in ground-based remote sensing of atmospheric constituents. The spatial distribution of various trace gases close to the instrument can be derived by combing several viewing directions. Multi-axis differential optical absorption spectroscopy (MAX-DOAS) technique, one of the remote sensing techniques for air quality measurements, uses the scattered sunlight as a light source and measures it at various elevation angles (corresponding to the viewing directions) by sequential scanning with a stepper motor. A MAX-DOAS system developed by GIST/ADEMRC has been applied to measuring trace gases in urban air and plumes of the volcano and fossil fuel power plant in January, May, and October 2004, respectively. MAX-DOAS spectra were analyzed to identify and quantify $SO_2,\;NO_2,\;BrO,\;and\;O_4$ (based on Slant Column Densities, SCD) in the urban air, volcanic plume, and fossil fuel power plant utilizing theirs specific structured absorption features in the UV-visible region. Vertical scan through the multiple elevation angles was performed at different directions perpendicular to the plume dispersion to retrieve cross-sectional distribution of $SO_2\;or\;NO_2$ in the plumes of the volcano and fossil fuel power plant. Based on the estimated cross sections of the plumes the mixing ratios were estimated to 580 $SO_2$ ppbv in the volcanic Plume, and 337 $NO_2\;and\;227\;SO_2$ ppbv in the plume of the fossil fuel power plant, respectively.