Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
권호 표지

Localization of the Neurons Projecting to the Gallbladder Meridian

족소양담경(足少陽膽經)에서 투사(投射)되는 신경원(神經元)의 표지부위(標識部位)에 대한 연구(硏究)

  • Ryuk Sang-Won (Dept. of Classics, College of Oriental Medicine, Woosuk University) ;
  • Lee Kwang-Gyu (Dept. of Oriental Pathology, College of Oriental Medicine, Woosuk University) ;
  • Lee Sang-Ryoung (Dept. of AM-Meridian & Pointology, College of Oriental Medicine, Woosuk University) ;
  • Kim Jum-Young (Dept. of AM-Meridian & Pointology, College of Oriental Medicine, Woosuk University) ;
  • Lee Chang-Hyun (Dept. of Anatomy, College of Oriental Medicine, Woosuk University) ;
  • Lee Bong-Hee (Dept. of Anatomy, College of Medicine, Cheju National University)
  • 육상원 (우석대학교 한의과대학 원전의사학교실) ;
  • 이광규 (우석대학교 한의과대학 한방병리학교실) ;
  • 이상룡 (우석대학교 한의과대학 경혈학교실) ;
  • 김점영 (우석대학교 한의과대학 경혈학교실) ;
  • 이창현 (우석대학교 한의과대학 해부학교실) ;
  • 이봉희 (제주대학교 의과대학 해부학교실)
  • Published : 2000.03.27
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Abstract

The purpose of this morphological studies was to investigate the relation to the meridian, acupoint and nerve. The common locations of the spinal cord and brain projecting to the the gallbladder, GB34 and common peroneal nerve were observed following injection of transsynaptic neurotropic virus, pseudorabies virus(PRV), into the gallbladder, GB34 and common peroneal nerve of the rabbit. After survival times of 96 hours following injection of PRV, the thirty rabbits were perfused, and their spinal cord and brain were frozen sectioned($30{\mu}m$). These sections were stained by PRV immunohistochemical staining method, and observed with light microscope. The results were as follows: 1. In spinal cord, PRV labeled neurons projecting to the gallbladder, GB34 and common peroneal nerve were founded in thoracic, lumbar and sacral spinal segments. Densely labeled areas of each spinal cord segment were founded in lamina V, VII, X, intermediolateral nucleus and dorsal nucleus. 2. In medulla oblongata, The PRV labeled neurons projecting to the gallbladder, GB34 and common peroneal nerve were founded in the A1 noradrenalin cells/C1 adrenalin cells/caudoventrolateral reticular nucleus, rostroventrolateral reticular nucleus, medullary reticular nucleus, dorsal motor nucleus of vagus nerve, nucleus tractus solitarius, raphe obscurus nucleus, raphe pallidus nucleus, raphe magnus nucleus, gigantocellular nucleus, lateral paragigantocellular nucleus, principal sensory trigeminal nucleus and spinal trigeminal nucleus. 3. In Pons, PRV labeled neurons were parabrachial nucleus, Kolliker-Fuse nucleus and cochlear nucleus. 4. In midbrain, PRV labeled neurons were founded in central gray matter and substantia nigra. 5. In diencephalon, PRV labeled neurons were founded in lateral hypothalamic nucleus, suprachiasmatic nucleus and paraventricular hypothalamic nucleus. 6. In cerebral cortex, PRV labeled neuron were founded in hind limb area.This results suggest that PRV labeled common areas of the spinal cord projecting to the gallbladder, GB34 and common peroneal nerve may be first-order neurons related to the somatic sensory, viscero-somatic sensory and symapathetic preganglionic neurons, and PRV labeled common area of the brain may be first, second and third-order neurons response to the movement of smooth muscle in gallbladder and blood vessels.These PRV labeled neurons may be central autonomic center related to the integration and modulation of reflex control linked to the sensory system monitoring the internal environment, including both visceral sensation and various chemical and physical qualities of the bloodstream. The present morphological results provide that gallbladder meridian and acupoint may be related to the central autonomic pathways.

Keywords

References

  1. 最新鍼灸學 金賢濟(外)
  2. 鍼灸學 上海中醫學院(編)
  3. 鍼灸學(上) 全國韓醫科大學 鍼灸學敎室
  4. Am J Chin Med. v.4 no.2 Acupuncture loci. Gunn GC
  5. Am J Chin Med. v.8 no.2 Anatomical findings at acupuncture loci Plummer JC
  6. Acupuncture Research Quarterly v.3 no.2 明堂圖的歷史硏究 Chen TH
  7. J Comp Neurol. v.140 Medullary cells of origin of vagal cardioinhibitory fibers in the pigeon Cohen DH;Schnell AM;MacDonald RL;Pitts LH
  8. J Auton Nerv Syst. v.25 Central origin of vagal nerve fibres innervating the fundus and corpus of the stomach in rat Ewart WR;Jones MV;King BF
  9. J Comp Neurol. v.208 A study of the extrinsic innervation of the guinea pig pylorus with the horseradish peroxidase tracing technique Elfvin LG;Lindh B
  10. 대한해부학회지 v.29 no.4 흰쥐의 뇌, 척수 및 신경절에서 내장기관과 관련된 신경원의 추적에 관한 미세형태학적 연구. 1. 부교감운동신경세포체의 표지부위 이창현;최종림;오인균;김동인;송창호;이무삼
  11. 대한해부학회지 v.29 no.6 흰쥐의 뇌, 척수 및 신경절에서 내장기관과 관련된 신경원의 추적에 관한 미세형태학적 연구 1Ⅰ. 감각신경세포체와 신경섬유의 표지부위 이창현;오인균;이동협;장극선;이무삼
  12. 침구학회지 v.13 no.2 WGA-HRP를 이용한 흰쥐 膵臟, 脾兪, 章文을 지배하는 운동 및 감각신경세포체의 표지부위 관찰 오인균;이창현;이호섭
  13. 대한침구학회지 v.15 no.1 神經追跡子를 이용한 흰쥐 胃, 胃兪, 中脘을 지배하는 운동 및 감각신경세포체의 표지부위 관찰 오인균;이창현;이호섭
  14. Brain Res. v.491 CNS cell groups regulating the sympathetic outflow of the adrenal gland as revealed by transneuronal cell body labeling with Pseudorabies virus Strack AM;Loewy AD
  15. 대한해부학회지 v.26 no.3 Pseudorabies 바이러스를 이용한 흰쥐 자궁의 신경지배에 관한 연구 이봉희;최완성;조경제;권해영;배지홍;송준경;이흥식;백상호
  16. 東醫生理學 金完熙(외)
  17. 대한원전의사학회지 v.9 馬王堆醫書와 黃帝內經에 나타난 經絡學說에 대한 연구 김용진
  18. 今釋黃帝內經(靈樞, 素問) 裵秉哲
  19. Am J Acupuncture v.9 Do meridians of acupuncture exit? ; A radioactive tracer study of the bladder meridian Raibulet T;Georgescu G;Sister IP
  20. Am Surgeon v.41 Anatomical comparison between acupuncture and nerve block Matsumoto T;Lyu BS
  21. Am J Chin Medicine v.3 The correspondence and acupuncture loci. Liu YM;Varela M;Oswald R
  22. William heinemann medical books LTD Scientific aspects of acupuncture Mann F
  23. Scientia Sinica. v.22 no.6 Role of peripheral afferent nerve fiber in acupuncture analgesia elicited by needling point Zusanli Lu G;Liang R;Xie J;Wang Y;He G
  24. Ann Rev Pharmacol Toxicol. v.22 Neurochemical basis of acupuncture analgesia Han JS;Terenius L
  25. J Physiol. v.337 Somatic and visceral inputs to the thoracic spinal cord of the cat ; Effects of noxious stimulation of the biliary system Cervero F
  26. J Neurophysiol. v.46 Characteristics of primate spinothalamic tract neurons receiving viscero-somatic convergent inputs in the T3-T5 segments Blair RW;Weber RN;Foreman RD
  27. Pain v.20 A positive feedback loop between spinal cord nociceptive pathways and antinociceptive areas of the cat's brain stem Cervero F;Wolstencroft JH
  28. J Comp Neurol. v.262 Viscerotopic representation of the upper alimentary tract in the medulla oblongata in the rat ; The nucleus ambiguus Bieger, D;Hopkins DA
  29. J Physiol. v.416 Localization of cardiomotor neurons in the anaesthetized rat ; Cholera toxin HRP conjugate and pseudorabies labelling Miselis RR;Rogers WT;Schwaber JS;Spyer KM
  30. J Neurosci. v.4 Tonic vasomotor control by the rostral ventrolateral medulla ; Effect of electrical or chemical stimulation of C1 adrenaline containing neurons on arterial pressure, heart rate and plasma catecholamines and vasopressin Ross CA;Ruggiero DA;Park DH;Joh TH;Sved AF;Fernandez-Pardol J;Saavedra JN;Reis DJ
  31. Exp. Neurol. v.84 Localization of the cells of origin for primary afferent fibers supplying the gallbladder of the cat Iwamoto GA;Waldrop TG;Longhurst JC;Ordway GA
  32. Circulation v.94 Reflex coronary vasoconstriction caused by gallbladder distension in anesthetized pigs Vacca G;Battaglia A;Grossini E;Mary DASG;Molinari C
  33. Brain Res. v.321 Cardiovascular and T2-T4 dorsal horn cell responses to gallbladder distention in the cat Ammons WS;Foreman RD
  34. J Comp Neurol. v.242 Projections from the nucleus tractus solitarii to the rostral ventrolateral medulla Ross CA;Ruggiero DA;Reis DJ
  35. Am J Physiol. v.258 Inhibition of rostral VLM by baroreceptor activation is relayed through caudal VLM Agarwal SK;Gelsema AJ;Calaresu FR
  36. J Comp Neurol. v.255 Spinal and trigeminal projections to the nucleus of the solitary tract ; A possible substrate for somatovisceral and viscerovisceral reflex activation Menetrey D;Basbaum AI
  37. J Comp Neurol. v.181 Nuclei of the solitary tract ; Efferent projections to the lower brain stem and spinal cord Loewy AD;Burton H
  38. Neuroscience v.3 Projections from the nucleus of the solitary tract in the rat Norgren R
  39. Brain Res Rev. v.3 Efferent connections of the ventral medulla oblongata in the rat Loewy AD;Wallach JH;McKellar S
  40. Science v.203 Raphe inhibition of sympathetic preganglionic neurons Cabot JB;Wild JM;Cohen DH
  41. Proc Natl Acad Sci. v.73 Opiate and stimulus produced analgesia, functional anatomy of a medullospinal pathway Basbaum AI;Clanton CH;Fields HL
  42. J Comp Neurol. v.240 Spinal and trigeminal dorsal horn projections to the parabrachial nucleus in the rat Cechetto DF;Standaert DG;Saper CB
  43. Brain Res. v.197 Efferent connections of the parabrachial nucleus in the rat Saper CB;Loewy AD
  44. Brain Res. v.174 Direct projections from the A5 catecholamine cell group to the intermediolateral cell column Loewy AD;McKellar S;Saper CB
  45. Brain Res. v.303 Baroreceptor mediated inhibition of A5 noradrenergic neurons Guyenet PG
  46. Brain Res. v.241 Decrease in blood pressure in response to L-glutamate microinjections into the A5 catecholamin cell group Neil JJ;Loewey AD
  47. Brain Res. v.172 Descending projections from the pontine micturition center Loewy AD;Saper CB;Baker RP
  48. Brain Res. v.528 Organization of tyrosin hydroxylase-immunoreactive and serotonin-immunoreactive brainstem neurons with axon collaterals to the periaqueductal gray and spinal cord in the rat Kwiat GC;Basbaum AI
  49. J Comp Neurol. v.308 Efferent projections of infra-limbic cortex of the rat Hurley KM;Herbert H;Moga MM;Saper CB
  50. Brain Res. v.117 Direct hypothalamo-auto-nomic connections Saper CB;Loewey AD;Swanson LW;Cowan WM
  51. J Comp Neurol. v.238 Long ascending projections to the midbrain from cells of lamina Ⅰand nucleus of the dorsolateral funiculus of the rat spinal cord Sweet JE;MMahon SB;Wall PD
  52. Brain Res. v.332 The cortico-medial amygdala in the central nervous system organization of agonistic behavior Luiten PGM;Koolhaas JM;de Boer S;Koopmans SJ
  53. Brain Res. v.223 Afferent projections to cardiovascular portions of the nucleus of the tractus solitarius in the rat Ross CA;Ruggiero DA;Reis DJ
  54. J Comp Neurol. v.309 Subregions of the periaqueductal gray topographically innervate the rostral ventral medulla in the rat Vanbockstale EJ;Aston-Johns G;Pieribone VA;Ennis M;Shipley MT
  55. J Neurosci. v.3 Evidence of periaqueductal cholecystokinin-substance P neurons projecting to the spinal cord Skirboll I;Hokfelt T;Dockray G;Rehfeld J;Brownstein M;Cuello AC
  56. J Comp Neurol. v.94 The paraventricular nucleus of the hypothalamus ; Cytoarchitectonic subdivisions and organization of projections to the pituitary, dorsal vagal complex and spinal cord as demonstrated by retrograde double-labeling methods Swanson LW;Kuypers HGJM
  57. J Comp Neurol. v.295 Organization of cortical, basal forebrain, and hypothalamic afferents to the parabrachial nucleus in the rat Moga MM;Herbert H;Hurley KM;Yasui Y;Gray TS;Saper, CB
  58. Am J Physiol. v.260 GABAa and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats Soltis RP;Dimicco JA
  59. Brain Res Bull. v.9 Origin and termination of the diencephalo-spinal dopamine system in the rat Skagerberg G;Bjorklunk A;Lindvall O;Schmidt RH