• PNF and Movement
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• v.5 no.1
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• pp.57-66
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• 2007

This review discusses the development of muscle receptors, in particular, that of muscle sensory neurons and monosynaptic stretch reflex circuit. The development of muscle sensory neurons and monosynaptic stretch reflex requires a series of steps including expression of neurotrophic transcriptional factors and their receptor. The monosynaptic stretch reflex circuit is unique neuronal circuit system, and highly precise synaptic connection systems. Thus, coordination of sensory-motor function in muscle receptors depend on the expression of distinct classes of molecular cues, and on the formation of selective synaptic connections between sensory-motor neurons and their target muscle. Recent neurotrophic and transcription factor expression studies have expanded our knowledge on how muscle sensory neuron is formed, and how sensory-motor system is developed.

• Journal of Life Science
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• v.30 no.11
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• pp.939-946
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• 2020

Stroke is one of the leading causes of neurological disability worldwide and stroke patients exhibit a range of motor, cognitive, and psychiatric impairments. GPR88 is an orphan G protein-coupled receptor (GPCR) that is highly expressed in striatal medium spiny neurons; its deletion results in poor motor coordination and motor learning. There are currently no studies on the involvement of GPR88 in stroke or in post-stroke brain function recovery. In this study, we found a decrease in GPR88 protein and mRNA expression levels in an ischemic mouse model using Western blot and real-time PCR, respectively. In addition, we observed that, among the three types of cells derived from the brain (brain microvascular endothelial cells, BV2 microglial cells, and HT22 hippocampal neuronal cells), the expression of GPR88 was highest in HT22 neuronal cells, and that GPR88 expression was downregulated in HT22 cells under oxygen-glucose deprivation (OGD) conditions. Moreover, pretreatment with RTI- 13951-33 (10 mg/kg), a brain-penetrant GPR88 agonist, ameliorated brain injury following ischemia, as evidenced by improvements in infarct volume, vestibular-motor function, and neurological score. Collectively, our results suggest that GPR88 could be a potential drug target for the treatment of central nervous system (CNS) diseases, including ischemic stroke.

• The Journal of Korean Academy of Sensory Integration
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• v.15 no.2
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• pp.35-45
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• 2017

Objective : The purpose of this study is to investigate the effect of modified Interactive Metronome (IM) program which is applicable to clinical practice based on the IM protocol on the behavioral symptoms, timing and motor function of children with Attention Deficit Hyperactivity Disorder (ADHD). Method : This study used one-group pretest-posttest research design. 13 ADHD children aged 7-12 years in Busan were participated in this study. The participants were underwent 24 sessions of 30 minutes intervention, 3 times a week. Evaluations were performed before- and after the intervention. Measurements used in this study were Korean-ADHD Rating Scale for behavior symptom, Long Form Assessment (LFA) for the timing, and second version of Bruininks-Oseretsky Test of Motor Proficiency (BOT-2) for the motor function. Results : There was a significant improvement in hyperactivity / impulsivity among the behavioral symptoms, and there was a statistically significant improvement in timing, hand coordination, and body coordination. Conclusion : Modified IM program for clinical application has significant effect on improving behavioral symptoms, timing and motor function of children with ADHD.

• PNF and Movement
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• v.17 no.1
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• pp.119-127
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• 2019

Purpose: The purpose of this study is to show the effect of elastic band on balance and functional ability in chronic stroke patients living in community. Methods: The subjects who participated in the study were 9 patients with chronic stroke. One of them gave up during the study, finally 8 patients performed. The intervention was conducted once a week for 10 weeks. In this study functional reach test (FRT), timed up and go test (TUG), Tinetti performance oriented mobility assessment (Tinetti-POMA) were measured for balance. The coordination training of arms and legs using the elastic band was performed in three positions as supine, side lying, sitting. One arm performed flexion-adduction- external rotation with elbow flexion pattern and the opposite side(diagonal) leg was performed flexion-adduction-external rotation with knee flexion pattern, the other arm's pattern was extension-abduction-internal rotation with elbow extension and the opposite side (diagonal) leg was in extension-abduction-internal rotation with knee extension pattern. The training was performed in each position for 15 minutes in per position. The participants had a five minute break after each training. Results: The results are as follows. FRT and Tinetti-POMA showed significant increase statistically in each position. The TUG showed significant decrease statistically in each position. Conclusion: Even though the coordination training with elastic band had performed once a week, it showed positive effects on balance in chronic stroke patients. Therefore, if we can suggest the appropriate frequencies of coordination training of arms and legs using the elastic band, it can be a method to improve daily life and life quality to patients with chronic stroke.

• Journal of Korean Physical Therapy Science
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• v.22 no.2
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• pp.1-10
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• 2015

Background : This study verified a correlation between gross motor performance measure (GMPM) and pediatric balance scale (PBS) for children, which are most widely used for assessment of children with cerebral palsy. Methods : The study subjects are 20 children aged between five and 13 who were diagnosed with cerebral palsy. Their mean age was $8.15{\pm}2.96years$ and consists of 15 males and 5 females. The subjects were divided into three groups according to muscle tone and motility disorders and then GMPM and PBS were assessed. In the assessment items in the GMPM, alignment, coordination, dissociated movement, stability, and weight shift were measured. The PBS consists of sitting to standing, standing to sitting, moving between chairs, standing without using hands, standing with one foot, turning 360 degrees, turning to look behind, retrieving object from floor, and reaching forward with outstretched arm while standing. A correlation of the collected data was analyzed using SPSS 18.0 for windows. Results : From Significant correlations were shown between items of GMPM and PBS as well as total scores of GMPM and PBS. Among them, coordination and weight transfer in the GMPM items had a high correlation with the PBS. In addition, the higher the GMPM total score was, the higher the PBS score was. Conclusion : This study result showed a significant correlation between GMPM and PBS, and this relation can be used to pediatric physical examination.

• The Journal of Korean Physical Therapy
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• v.32 no.1
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• pp.44-51
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• 2020

Purpose: This study translated the developmental coordination disorder questionnaire'07 (DCDQ'07) into Korean and investigated the psychometric properties of the Korean DCDQ (DCDQ-K) using validation processes. Methods: The subjects were 300 parents with typically developing children aged 5-15 years (162 girls and 138 boys, mean age 9.24 years, SD 2.59) across the country. To develop the Korean DCDQ, a forward-backward-original author feedback-panel meeting-pilot study with parents was done. The internal consistency, test-retest reliability performed two weeks apart, content validity, discriminative validity, convergent validity, and constructive validity were examined with the pre-version of the DCDQ-K. Results: Approximately 15.33% of the subjects were probably shown DCD using DCDQ-K. Significant differences in age and province were observed in the DCDQ-K total score. The reliabilities and validities were good in the DCDQ-K. Conclusion: The DCDQ-K is a reasonable screening tool for DCD children.

• Journal of the Korean Society of Physical Medicine
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• v.18 no.3
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• pp.65-72
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• 2023

PURPOSE: This study assessed the influence of bilateral coordination exercises on unstable support surfaces on leg muscle activation and balance in stroke patients. METHODS: Two groups were recruited for comparison: an experimental group of 10 individuals who performed bilateral coordination exercises on unstable surfaces and a control group of 10 individuals who performed the same exercises on stable surfaces. All participants were assigned randomly. Pre-tests were conducted to measure the leg muscle activation and balance levels of the participants prior to the experiment. The intervention was comprised of three 30-minute weekly sessions for four weeks, followed by a post-test after the four-week period. RESULTS: Significant differences were identified within the experimental group in relation to all muscles (p < .01) and balance (p < .05). Within the control group, significant differences were identified in relation to the rectus femoris muscle, biceps femoris muscle, and balance (p < .05). Significant differences between the two groups were only observed in relation to the tibialis anterior and soleus muscles (p < .05). CONCLUSION: Only the tibialis anterior and soleus muscles showed significant differences between the two groups. This effectiveness may be attributed to using an ankle strategy to maintain body balance during exercise on unstable surfaces.

• Journal of Korea Entertainment Industry Association
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• v.15 no.1
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• pp.221-228
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• 2021

This study aims to provide basic data for developing hand functional training programs using a keyboard to see if there is a relationship between the smart keyboard input speed using both hands, the Dexterity of the hand and the eye-hand coordination ability. The smartphone keyboard input speed, Purdue Pegboard, Grooved Pegboard Test, and Korean-Developmental-Test of Visual Perception-Adolescent were evaluated for 40 university students Province. An independent sample t-test and one-way ANOVA were conducted to identify differences in smartphone keyboard input speed, dexterity, eye-hand coordination ability and visual-motion using both hands according to the general characteristics of the subjects. Pearson correlation was also conducted to find out the relationship between hand-used smartphone keyboard input speed, hand dexterity, eye-hand coordination ability and visual-motor. As a result, the smartphone keyboard input speed using both hands showed a correlation with the dominant hand in the Purdue Pegboard Test (r=-.313, p<.05). In addition, the input speed of the smartphone keyboard is Copying(r=-.333, p<.05), Visual Motor Search(r=.455, p<.01), Visual Motor speed(r=-.453, p<.01) and Form Constancy (r=-.341, p<.05) in the item of K-DTVP-A. Therefore, it is believed that it will be helpful in the development of a treatment program using a smartphone, and it is expected that the effectiveness of a treatment program using a smartphone will be proven through additional experimental studies in the future.

• Journal of Convergence for Information Technology
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• v.11 no.4
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• pp.153-160
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• 2021

Goal of this study is to introduce newly developed Oral Motor Facilitation Technique(OMFT), to identify effect of oral motor therapy on oral praxis and oral function of Down syndrome child. OMFT is comprehensive oral motor therapy for improving sensory adaptation, oral sensori-motor function, oral motor coordination of oro-facial structure by therapist's direct manual stroking. Subject was 10years old down syndrome boy. Treatment was practiced 8 times, 15minutes per time, from May to July, 2020. Oral praxis, drooling, quality of chewing ability were tested before and after treatments. Every single items of Oral Praxis Test was increased. Severity and frequency of drooling were decreased. Quality of chewing ability is improved. Through this case study, we can find the positive effect of OMFT on oral praxis, drooling, chewing ability of Down syndrome child.

• Therapeutic Science for Rehabilitation
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• v.9 no.2
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• pp.119-135
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• 2020

Objective : The purpose of this study was to investigate the effects of bimanual intensive training on Upper Extremity Function and activities of daily living in stroke patients. Methods : The subjects were 18 patients who were diagnosed with hemiplegic stroke. They were randomly assigned to bimanual intensive training group (n=9) and unilateral intensive group (n=9). Bimanual training group performed bimanual task and unilateral training group performed one hand task for 1 hour per session, 5 times a week, for 4 weeks. Chi-square test, Wilcoxon signed rank test, and Mann-Whitney U test were used for analysis. Results : The results showed that, upper extremity motor function and bimanual coordination were significantly improved in patients in the bimanual training group (p<.05). Additionally, the ratio of affected hand use and amount of use/quality of movement in the hemiplegic upper extremity in activities of daily living for patients in the bimanual training group were significantly improved (p<.05). Although the unilateral group improved motor upper extremity function and activities of daily living in the upper extremity (p<.05), it was not significantly different from that in the bimanual training group. In between-group comparison, bimanual coordination and ratio of the affected hand use in a day were significantly different (p<.05). Conclusion : It is reasonable to conclude that bimanual intensive training therapy is an effective intervention method to improve upper extremity motor function, and activities of daily living in stroke patients.