• The Korean Journal of Physiology and Pharmacology
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• v.26 no.4
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• pp.263-275
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• 2022

There is a paucity of detailed data related to the effect of senescence on the mitochondrial antioxidant capacity and redox state of senescent human cells. Activities of TCA cycle enzymes, respiratory chain complexes, hydrogen peroxide (H₂O₂), superoxide anions (SA), lipid peroxides (LPO), protein carbonyl content (PCC), thioredoxin reductase 2 (TrxR2), superoxide dismutase 2 (SOD2), glutathione peroxidase 1 (GPx1), glutathione reductase (GR), reduced glutathione (GSH), and oxidized glutathione (GSSG), along with levels of nicotinamide cofactors and ATP content were measured in young and senescent human foreskin fibroblasts. Primary and senescent cultures were biochemically identified by monitoring the augmented cellular activities of key glycolytic enzymes including phosphofructokinase, lactate dehydrogenase, and glycogen phosphorylase, and accumulation of H₂O₂, SA, LPO, PCC, and GSSG. Citrate synthase, aconitase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, isocitrate dehydrogenase, and complex I-III, II-III, and IV activities were significantly diminished in P25 and P35 cells compared to P5 cells. This was accompanied by significant accumulation of mitochondrial H₂O₂, SA, LPO, and PCC, along with increased transcriptional and enzymatic activities of TrxR2, SOD2, GPx1, and GR. Notably, the GSH/GSSG ratio was significantly reduced whereas NAD⁺/NADH and NADP⁺/NADPH ratios were significantly elevated. Metabolic exhaustion was also evident in senescent cells underscored by the severely diminished ATP/ADP ratio. Profound oxidative stress may contribute, at least in part, to senescence pointing at a potential protective role of antioxidants in aging-associated disease.

• Journal of Wetlands Research
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• v.24 no.1
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• pp.38-43
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• 2022

Smart sewage treatment plant means creating a safe and clean water environment by establishing an ICT-based real-time monitoring, remote control management and intelligent system for the entire sewage treatment process. The core technology of such a smart sewage treatment plant can be operation control technology using measuring instruments. This research team analyzed and suggested the operation control technologies necessary for the establishment of the intelligent business by referring to the intelligent research projects of the sewage treatment plant in progress in Korea. As a result of the analysis, a total of six removal technologies were presented, including control by scale, reflow water control, linked treated water control, chemical quantity control, winter operation control, and total organic carbon control. By size, standards that can be classified into small and medium-sized large-scale are presented, and in the case of reflow water control, the location of water quality and flow sensors capable of managing reflow water is suggested. In the case of the linked treated water control, the influence and control points of the linked treated water on the sewage treatment plant were presented, and in the case of the chemical injection volume control, a system capable of optimizing the amount of chemical injection according to the introduction of an intelligent sewage treatment plant was presented. In the case of winter operation, the sensors and pumps to be controlled are suggested when considering the decrease in nitrification due to the decrease in water temperature. In the case of total organic carbon control, an interlocking system considering the total amount of pollution in the future was proposed. These operation control scenarios are expected to be used as basic data to be used in intelligent sewage treatment algorithms and scenarios in the future.

• Journal of the Korean Institute of Rural Architecture
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• v.24 no.1
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• pp.9-17
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• 2022

Rural spaces are increasingly valuable as areas for introducing renewable energy infrastructure to achieve carbon neutrality. Rural areas are the living grounds of rural residents, and the balance of conservation and development for rural areas is important for the introduction of reasonable facilities. In order to maintain a balance between development and preservation and to introduce reasonable renewable energy facilities, it is necessary to develop a current status survey and an effective survey method to utilize a space capable of introducing renewable energy facilities such as idle land and vacant houses. Therefore, this study was conducted to verify the readability using an unmanned aerial vehicle, and the main results are as follows. The detection of photovoltaic power generation facilities using unmanned aerial vehicles was effective in analyzing the location and area of photovoltaic panels located on the roofs of buildings, and it was possible to calculate the expected power generation by region through the area calculation of photovoltaic panels. The vacant house detection can be used to select an investigation target for an vacant house condition survey as it can identify damage to buildings that are expected to be empty houses, management status, and electricity supply facilities through aerial photos. It is judged that the unmanned aerial vehicle detection capability can be utilized as a method to improve the efficiency of investigation and supplement the data related to solar power generation facilities and vacant houses provided by public institutions. Although this study detected the status of solar power generation facilities and vacant houses through high-resolution aerial image analysis, as a follow-up study, automatic measurement methods using the temperature difference of solar power generation facilities and general characteristics of vacant houses that can be read from the air were investigated. If the deriving research is carried out, it is judged that it will be possible to contribute to the improvement of the accuracy of the detection result using the unmanned aerial vehicle and the expansion of the application range.

• Korean Journal of Remote Sensing
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• v.38 no.3
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• pp.237-250
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• 2022

In this study, we propose a method to estimate the biomass of invertebrate grazers from the videos with underwater drones by using a multi-object tracking model based on deep learning. In order to detect invertebrate grazers by classes, we used YOLOv5 (You Only Look Once version 5). For biomass estimation we used DeepSORT (Deep Simple Online and real-time tracking). The performance of each model was evaluated on a workstation with a GPU accelerator. YOLOv5 averaged 0.9 or more mean Average Precision (mAP), and we confirmed it shows about 59 fps at 4 k resolution when using YOLOv5s model and DeepSORT algorithm. Applying the proposed method in the field, there was a tendency to be overestimated by about 28%, but it was confirmed that the level of error was low compared to the biomass estimation using object detection model only. A follow-up study is needed to improve the accuracy for the cases where frame images go out of focus continuously or underwater drones turn rapidly. However,should these issues be improved, it can be utilized in the production of decision support data in the field of invertebrate grazers control and monitoring in the future.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.610-622
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• 2021

The DECOVALEX project is one of the representative international cooperative projects to enhance the understanding of the complex Thermo-Hydro-Mechanical-Chemical(THMC) coupled behavior in the high-level radioactive waste disposal system based on the numerical simulation. DECOVALEX-2023 is the current phase consisting of 7 tasks, and Task C aims to model the THM coupled behavior in the disposal system based on the Full-scale Emplacement (FE) experiment at the Mont-Terri underground rock laboratory. This study performs the numerical simulation based on the OGS-FLAC developed for the current study. In the numerical model, we emplaced the heater with constant power horizontally based on the FE experiment and monitored the pressure development, temperature increase, and mechanical deformation at the specific monitoring points. We monitored the capillary pressure as the primary effect inducing the flow in the buffer system, and thermal stress and pressurization were dominant in the surrounding rocks' area. The results will also be compared and validated with the other participating groups and the experimental data further.

• Pediatric Infection and Vaccine
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• v.29 no.1
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• pp.37-45
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• 2022

Purpose: During the coronavirus disease 2019 (COVID-19) pandemic, we conducted a Delphi survey that included the experts from the field of COVID-19 immunization in children aged 5-11 years. The aim was to organize collective expert opinions on COVID-19 vaccination in young children in the Republic of Korea, and so thus assist the vaccination policy. Methods: The panels included pediatric infectious disease specialists, preventive medicine experts, infectious disease physicians, and COVID-19 vaccine experts consulting the Ministry of Health and Welfare. The Delphi survey was conducted online using a questionnaire from February 14 to February 27, 2022. Results: The Delphi panels agreed that children were vulnerable to COVID-19, and the severity of illness was modest. Furthermore the panels reported that children with chronic illness were more susceptible to a worsening clinical course. There were generally positive opinions on the effectiveness of COVID-19 vaccination in children aged 5-11 years, and experts gathered a slightly positive opinion that the adverse events of pediatric COVID-19 were not numerous. The benefits of COVID-19 vaccination were evaluated at a level similar to the potential risks in children. Currently, the only approved mRNA platform vaccine in children seemed to be sustainable; however, the recombinant protein platform COVID-19 vaccines were evaluated as better options. Conclusions: Due to the surge of the Omicron variant and an increase in pediatric cases, the COVID-19 vaccination in young children may have to be considered. Panels had neutral opinions regarding the COVID-19 vaccination in children aged 5-11 years. Thus monitoring of the epidemiology and the data about the safety of COVID-19 vaccination should be continued.

• Applied Chemistry for Engineering
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• v.33 no.6
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• pp.563-573
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• 2022

This work aimed to develop a new equation for turbidity (Turb) simulation and prediction using statistical methods based on principal component analysis (PCA) and multiple linear regression (MLR). For this purpose, water samples were collected monthly over a five year period from Cheurfa dam, an important reservoir in Northwestern Algeria, and analyzed for 12 parameters, including temperature (T°), pH, electrical conductivity (EC), turbidity (Turb), dissolved oxygen (DO), ammonium (NH₄⁺), nitrate (NO₃^-), nitrite (NO₂^-), phosphate (PO₄^3-), total suspended solids (TSS), biochemical oxygen demand (BOD₅) and chemical oxygen demand (COD). The results revealed a strong mineralization of the water and low dissolved oxygen (DO) content during the summer period. High levels of TSS and Turb were recorded during rainy periods. In addition, water was charged with phosphate (PO₄^3-) in the whole period of study. The PCA results revealed ten factors, three of which were significant (eigenvalues >1) and explained 75.5% of the total variance. The F1 and F2 factors explained 36.5% and 26.7% of the total variance, respectively and indicated anthropogenic pollution of domestic agricultural and industrial origin. The MLR turbidity simulation model exhibited a high coefficient of determination (R² = 92.20%), indicating that 92.20% of the data variability can be explained by the model. TSS, DO, EC, NO₃^-, NO₂^-, and COD were the most significant contributing parameters (p values << 0.05) in turbidity prediction. The present study can help with decision-making on the management and monitoring of the water quality of the dam, which is the primary source of drinking water in this region.

• Korean Journal of Remote Sensing
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• v.38 no.6_1
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• pp.991-1005
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• 2022

Satellite imaging is an effective supplementary data source for detecting and verifying nuclear activity. It is also highly beneficial in regions with limited access and information, such as nuclear installations. Time series analysis, in particular, can identify the process of preparing for the conduction of a nuclear experiment, such as relocating equipment or changing facilities. Differences in the semantic segmentation findings of time series photos were employed in this work to detect changes in meaningful items connected to nuclear activity. Building, road, and small object datasets made of KOMPSAT 3/3A photos given by AIHub were used to train deep learning models such as U-Net, PSPNet, and Attention U-Net. To pick relevant models for targets, many model parameters were adjusted. The final change detection was carried out by including object information into the first change detection, which was obtained as the difference in semantic segmentation findings. The experiment findings demonstrated that the suggested approach could effectively identify altered pixels. Although the suggested approach is dependent on the accuracy of semantic segmentation findings, it is envisaged that as the dataset for the region of interest grows in the future, so will the relevant scope of the proposed method.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.5
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• pp.639-650
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• 2022

In areas where large-scale sediment transport occurs, it is important to apply appropriate countermeasure method because the phenomenon tends to accelerate by time duration. Among the various countermeasure methods applied so far, beach nourishment needs to be reviewed as an erosion prevention measure because the erosion pattern is mitigated and environmentally friendly depending on the particle size. In the case of beach nourishment. a detailed review is required to determine the size, range, etc., of an appropriate particle diameter. In this study, we investigated the characteristics of the related topographic change using the change in the particle size of nourishment materials, the application of partial area, and the condition under the coexistence of waves and wind as variables because those factors are hard to be analyzed and interpreted within results and limitation of that the existing numerical models are not able to calculate and result out so that it is required that phenomenon or efforts are reviewed at the same time through physical model experiments, field monitoring and etc. So we attempt to reproduce the tendency of beach erosion and deposition and predict possible phenomena in the future using machine learning techniques for phenomena that it is not able to be interpreted by numerical models. we used the hydraulic experiment results for the training data, and the accuracy of the prediction results according to the change in the training method was simultaneously analyzed. As a result of the study it was found that topographic changes using machine learning tended to be similar to those of previous studies in short-term predictions, but we also found differences in the formation of scour and sandbars.

• Korean Journal of Remote Sensing
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• v.38 no.5_3
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• pp.901-912
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• 2022

The frequency of disasters is increasing due to global climate change, and unusual heavy rains and rainy seasons are occurring in Korea. Periodic monitoring and rapid detection are important because these weather conditions can lead to drought and flooding, causing secondary damage. Although research using optical images is continuously being conducted to determine the waterbody, there is a limitation in that it is difficult to detect due to the influence of clouds in order to detect floods that accompany heavy rain. Therefore, there is a need for research using synthetic aperture radar (SAR) that can be observed regardless of day or night in all weather. In this study, using Sentinel-1 SAR images that can be collected in near-real time as open data, the UNet model among deep learning algorithms that have recently been used in various fields was applied. In previous studies, waterbody detection studies using SAR images and deep learning algorithms are being conducted, but only a small number of studies have been conducted in Korea. In this study, to determine the applicability of deep learning of SAR images, UNet and the existing algorithm thresholding method were compared, and five indices and Sentinel-2 normalized difference water index (NDWI) were evaluated. As a result of evaluating the accuracy with intersect of union (IoU), it was confirmed that UNet has high accuracy with 0.894 for UNet and 0.699 for threshold method. Through this study, the applicability of deep learning-based SAR images was confirmed, and if high-resolution SAR images and deep learning algorithms are applied, it is expected that periodic and accurate waterbody change detection will be possible in Korea.