• KSBB Journal
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• v.22 no.5
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• pp.366-369
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• 2007

In this study, the feasibility of reusing the eluent was confirmed by monitoring its specific gravity during the chromatographic purification of paclitaxel from plant cell cultures. The specific gravity of the eluent (methanol/water = 70/30, v/v) was measured prior to its elution through the hydrophobic resin column. The measurement showed a specific gravity of 0.853. The discharged eluent from the column outlet was first evaporated under vacuum pressure. The evaporated eluent was collected and condensed into a liquid eluent again, followed by the HPLC analysis in order to check the presence of any trace of impurity. Even if the specific gravity of the liquid eluent is varied from 0.853 as a result of the evaporation and condensation, the eluent can still be reused after it specific gravity is adjusted by the addition of methanol or water. The reuse of the eluent resulted in the paclitaxel yield of 86% with a purity of 95% which were closely similar to those of before the eluent reuse. These results indicate that the strategy of reusing the eluent on the basis of the specific gravity analysis was successfully implemented in this study.

• Advanced Industrial SCIence
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• v.1 no.2
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• pp.24-29
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• 2022

Recently, smart farm research that applies IoT technology to various farms is being actively conducted to improve agricultural cooling power and minimize cost reduction. In particular, methods for automatically and remotely controlling environmental information data around smart farms through IoT devices are being studied. This paper proposes a processing model that can maintain an optimal growth environment by monitoring environmental information data collected from smart farms in real time based on machine learning. Since the proposed model uses machine learning technology, environmental information is grouped into multiple blockchains to enable continuous data collection through rich big data securing measures. In addition, the proposed model selectively (or binding) the collected environmental information data according to priority using weights and correlation indices. Finally, the proposed model allows us to extend the cost of processing environmental information to n-layer to a minimum so that we can process environmental information in real time.

• Journal of Korean Society of Forest Science
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• v.101 no.4
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• pp.656-662
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• 2012

This study has been undertaken to research the characteristics of growth of Pinus thunbergii Parl., which were planted in Uljin-gun, Gyeongbuk, Coast Disaster Prevention Forest. The total amount of 3600 trees of 9 sand dune stabilizing hedges were monitored in the past 4 years. The relationship between tree growth with environmental factors such as wind speed, soil conditions and sand-accumulation fences has been compared and investigated. To increase the growth increment of coastal disaster prevention forests, the development of sand-accumulating fences is the most important factor in controlling wind speed effectively. The monitoring for the maximizing wind-break effect of the sand-accumulating fences should be investigated when building coastal disaster prevention forests.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.5
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• pp.50-57
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• 2004

For the application of structural health monitoring such as AE detection, a stabilized FBG sensor system with wide dynamic range was proposed. A tunable Fabry-Perot filter with narrow free spectral range(FSR) was used to simplify the multiplexing demodulator for FBG vibration sensors. Stabilization controlling system was also developed for the maintenance of maximum sensitivity of the sensors. In order to verify the performance of the proposed FBG vibration sensor system, we measured sensitivity, and the system showed the average sensitivity of 256 $n{\in}_{mas}/{\sqrt{Hz}}$. Finally, multi-points vibration tests using in-line FBG sensors were conducted to validate the multiplexing performance of the FBG system.

• Journal of Chest Surgery
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• v.13 no.4
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• pp.346-355
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• 1980

It has been proposed that wide individual variation in response to heparin be not considered in the conventional set protocol for the control of heparin and protamine during extracorporeal circulation. In this paper, two protocol of heparin and protamine therapy were compared to assess the role of the Activated Clotting Time [ACT] in relation to heparin, protamine, and postoperative blood loss and transfusion. The study groups consisted of the 31 patients [adults 15 and children 16] anticoagulated with the conventional heparin protocol and the 31 patients [adults 15 and children 16] anticoagulated with ACT protocol during extracorporeal circulation. In the conventional heparin protocol, two mg of heparin per kg was administered initially with an additional 0.75 mg of heparin per kg every 30 minutes of extracorporeal circulation, and reversal was accomplished with protamine in a dose of 1.5 times the total milligram of heparin. In the ACT protocol, two mg of heparin per kg was administered initially with an additional dose of heparin enough to reach an ACT of 480 seconds [within safe zone 300 to 600 seconds] from the patient`s dose response curve every 1 hour of extracorporeal circulation, and reversal was done with protamine in a dose of 1.3 times the milligram of the residual heparin. The results were summarized as follows. After a dose of 2 mg per kg of heparin, the patient`s ACT varied from 240 to 600 seconds in adults and from 240 t~ 660 seconds in children. In the ACT group the total amount of heparin administered was markedly reduced when compared to the conventional group, and less protamine was required to neutralize heparin. The dose of heparin administered decreased from 7.07 [SE 0.42] mg/kg of the conventional group to 4.92 [SE 0.32] mg/k8 of the ACT group in adults and from 10.17 [SE 1.15] mg/kg to 5.23 [SE 0.24] mg/kg in children, which represent 30.4% and 48.6% decrease respectively. The dose of protamine administered for reversal decreased from 10.6 [SE 0.63] mg/kg of the conventional group to 3.35 [SE 0.35] mg/kg of the ACT group in adults and from 15.7 [SE 1.70] mg/kg to 3.26 [SE 0.27] mg/kg in children, which represent 68.4% and 79.2% respectively. The ratio of protamine to heparin administered in the conventional group was 1.50:1 in adults and 1.54:1 in children, but in the ACT group 0.68:1 in adults and 0.62:1 in children. Postoperative blood loss and transfusion revealed no statistically significant difference between the two groups. Although six patients in the conventional group and one in the ACT group needed re-exploration for continuous hemorrhage, no case of generalized oozing was encountered, and in each case a definite bleeding site was identified. Author would like emphasizing the value of the ACT protocol in controlling heparin and protamine administration during extracorporeal circulation.

• Parasites, Hosts and Diseases
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• v.59 no.5
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• pp.507-512
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• 2021

Since 1993, vivax malaria has been recognized as a public health burden in Korea. Despite of pan-governmental malaria-control efforts and the dramatic reduction in the burden of this disease over the last 10 years, vivax malaria has not been well controlled and has remained continuously endemic. We focused interviewed and examined the charts of 28 confirmed vivax malaria patients given malarial therapy for whom daily records were kept from Gimpo-si, Gyeonggi-do of Korea. Various epidemiological characteristics of vivax malaria, including the incubation period, medication used, and recurrence, and an evaluation of the parasitic characteristics from the focused interviews of patients from this region are described here. Most of the participants indicated the 3 most common symptoms of malaria (headache, chills and fever). Of the 28 cases, 2 experienced a second attack and there were 17 and 11 cases with short- and long-term incubation periods, respectively, yielding a short-term to long-term ratio of 1.5. Based on the parasitemia stages, most of the participants were tested at 5 to 7 days (11 cases) and 7 to 15 days (11 cases) after initial wave of asexual parasites. In conclusion, public health authorities should consider developing management measures to decrease the time lag for diagnosis and drafting unified and robust guidelines for drug use for malaria and drawing up unified and robust guidelines on the use of medication for malaria. It also suggests that routine monitoring, surveillance, and precise medical surveys in high-risk vivax malaria endemic areas are pivotal to controlling this persistent public disease and finally eliminating it from Korea.

• Parasites, Hosts and Diseases
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• v.53 no.5
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• pp.535-543
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• 2015

Integrated control strategies are important for sustainable control of schistosomiasis and soil-transmitted helminthiasis, despite their challenges for their effective implementation. With the support of Good Neighbors International in collaboration with National Institute of Medical Research, Mwanza, Tanzania, integrated control applying mass drug administration (MDA), health education using PHAST, and improved safe water supply has been implemented on Kome Island over 5 years for controlling schistosomiasis and soil-transmitted helminths (STHs). Baseline surveys for schistosomiasis and STHs was conducted before implementation of any integrated control strategies, followed by 4 cross-sectional follow-up surveys on randomly selected samples of schoolchildren and adults in 10 primary schools and 8 villages, respectively, on Kome islands. Those follow-up surveys were conducted for impact evaluation after introduction of control strategies interventions in the study area. Five rounds of MDA have been implemented from 2009 along with PHAST and improved water supply with pumped wells as other control strategies for complementing MDA. A remarkable steady decline of schistosomiasis and STHs was observed from 2009 to 2012 with significant trends in their prevalence decline, and thereafter infection rate has remained at a low sustainable control. By the third follow-up survey in 2012, Schistosoma mansoni infection prevalence was reduced by 90.5% and hookworm by 93.3% among schoolchildren while in adults the corresponding reduction was 83.2% and 56.9%, respectively. Integrated control strategies have successfully reduced S. mansoni and STH infection status to a lower level. This study further suggests that monitoring and evaluation is a crucial component of any large-scale STH and schistosomiasis intervention.

• Journal of Food Hygiene and Safety
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• v.29 no.1
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• pp.6-15
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• 2014

This study was performed to acquire the information on the foodborne pathogen risk management programs in a couple of developed countries by the expert meeting and searching the information on the web. The backgrounds, strategies and effects related to microbial hazards of the foodborne pathogen reduction programs in fresh produce (US), Escherichia coli O157:H7 in ground beef (US), Salmonella in chicken, pork and eggs (Denmark), and Vibrio parahaemolyticus in seafood (Japan) were investigated for case study. A comparison among the pathogen reduction programs was conducted to find advantages and disadvantages and implications of the policies to bring out implications of the programs. A model for foodborne pathogen reduction program was developed based on both the CODEX risk management scheme and the case studies as follows; 1) preliminary risk management activities, 2) planing a foodborne pathogen reduction program, 3) option identification and selection, 4) implementation (conducting the each stake-holders role and applying the intervention methods), 5) monitoring activities, 6) interim review, 7) continuation or amendment of implementation method by the interim review before achieving the goal, and 8) final review and additional cost-benefit analysis if necessary. This proposed model according to the role of the stake-holders can be used to conduct microbial risk management programs in Korea in the near future.

• Korean Journal of Environmental Agriculture
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• v.35 no.4
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• pp.247-255
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• 2016

BACKGROUND: Acrylamide (CAS No. 79-06-1) is known to be a carcinogenic compound, and is classified as a Group 2A compound by the International Agency for Research on Cancer (IARC, 1994). Acrylamide can be generated during the browning process via the non-enzymatic Maillard reaction of carbohydrates such as reducing sugars and of amino acids such as asparagine, both of which occur at a temperature above $120^{\circ}C$. Potato tubers contain reducing sugars, and thus, this will affect the safety of processed potato products such as potato chips and French fries. In order to reduce the level of acrylamide in potato processed products, it is therefore necessary to understand factors that affect the reducing sugar content of potatoes, such as environmental factors and potato storage conditions, as well as understanding factors affecting acrylamide formation during potato processing itself. METHODS AND RESULTS: Potatoes were cultivated in eight regions of Korea; For each of these different environments, soil physico-chemical characteristics such as pH, electrical conductivity, total nitrogen, available phosphate, and exchangeable cation content were measured and correlations with potato reducing sugar content and potato chip acrylamide levels were examined. The reducing sugar content in potato during storage for three months was determined and acrylamide level in potato chip was analyzed after processing. The storage temperature levels were $4^{\circ}C$, $8^{\circ}C$, or $10^{\circ}C$, respectively. The acrylamide content of chips prepared from potatoes stored at $10^{\circ}C$ or $20^{\circ}C$ for one month was analyzed and the different frying times were 2, 3, 5, and 7 min. CONCLUSION: This study showed that monitoring and controlling the phosphate content within a potato field should be sufficient to avoid producing brown or black potato chips. For potatoes stored at low temperatures, a reconditioning period ($20^{\circ}C$ for 20 days) is required in order to reduce the levels of reducing sugars in the potato and subsequently reduce the acrylamide and improve chip coloration and appearance.

• Journal of Soil and Groundwater Environment
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• v.17 no.2
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• pp.37-46
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• 2012

This study was conducted to identify groundwater recharge and discharge amounts of a representative urban-rural composite area located in Yongin city, Kyounggi-do, Korea. Groundwater recharge would be affected by mainly two processes in the study area: rainfall and leakage from public water pipelines including water-supply and sewage system. Groundwater recharge rate was estimated to be 13.5% by applying annual groundwater level data from two National Groundwater Monitoring Stations to the master regression curve method. Subsequently, the recharge amounts were determined to be $13,253{\times}10^3m^3/yr$. Leakage amounts from water-supply and sewage system were estimated to be $3,218{\times}10^3$ and $5,696{\times}10^3m^3/yr$, respectively. On the whole, a total of the recharge amounts was $22,167{\times}10^3m^3/yr$, of which 60% covers rainfall recharge and 40% pipeline leakage. Groundwater discharge occurred through three processes in the composite area: baseflow, well pumping, and discharge from urban infrastructure including groundwater infiltration into sewage pipeline and artificial extraction of groundwater to protect underground facilities from submergence. Discharge amounts by baseflow flowing to the Kiheung agricultural reservoir and well pumping were estimated to be $382{\times}10^3$ and $1,323{\times}10^3m^3/yr$, respectively. Occurrence of groundwater infiltration into sewage pipeline was rarely identified. Groundwater extraction amounts from the Bundang subway line as an underground facility were identified as $714{\times}10^3m^3/yr$. Overall, a total of the discharge amounts was determined to be $2,419{\times}10^3m^3/yr$, which was contributed by 29% of artificial discharge. Even though groundwater budget of the composite area was identified to be a surplus, it should be managed for a sound groundwater environment by changing deteriorated pipelines and controlling artificial discharge amounts.