• International Journal of Air-Conditioning and Refrigeration
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• 제9권2호
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• pp.8-18
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• 2001

The direct simulation Monte Carlo Method is applied to investigate the two-dimensional flow fields of a turbomolecular pump(TMP) in both molecular and transition flow regions. The pumping characteristics of the TMP are investigated for a wide range of the Knudsen number. The maximum of compression ratio and of pumping speed strongly depend on the Knudsen number in transition region, while they weakly depend on the Knudsen number in free molecular flow region. The present numerical results show good agreement with the previously known experimental data. Finally. the results of the single blade row in both molecular and transition regions are used to predict the overall performance of a TMP, which has three kinds of blade with 24-rows.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2009년도 추계학술대회 논문집
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• pp.453-453
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• 2009

• 설비공학논문집
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• 제12권1호
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• pp.83-94
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• 2000

The performance of a turbomolecular pump(TMP) in both molecular and transition flow regions is predicted by the numerical solutions of the Boltzmann equation obtained by the direct simulation Monte Carlo method. The compression characteristics of the TMP are investigated for a wide range of the Knudsen number( Kn ). The maximum compression ratios strongly depend on Kn in transition region, while do they weakly on Kn in free molecular flow region. The present numerical results of the single blade row in both molecular and transition regions are used to predict the overall performance of a TMP, which has three kinds of blade with 24-rows.

• 설비공학논문집
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• 제8권2호
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• pp.219-229
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• 1996

In the free molecular flow range, the pumping performance of a turbomolecular pump has been predicted by calculation of the transmission probability employing the integral method and the test particle Monte-Carlo method. The velocities of molecules incident upon a moving blade are given by the random numbers, which are sampled from the Maxwell molecular velocity distribution function. The present results agree quantitatively with the previous known numerical results. For a multi-stage pump, the velocity profile of molecules between two blade rows is not Maxwell distribution. In this case, the Monte-Carlo method is employed to calculate the overall transmission probability for the entire set of blade rows. When the results of the approximate method combining the single stage solutions are compared with those of the Monte-Carlo method for the pump having six rows at C=0.6, the approximate method overestimates as much as 36% in the maximum compression ratio and 19% in the maximum pumping speed than does the Mote-Carlo method.

• 대한기계학회논문집B
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• 제24권6호
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• pp.860-869
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• 2000

Numerical and experimental investigations are performed for the molecular transition and slip flows in pumping channels of a disk-type drag pump. The flow occurring in the pumping channel develops from the molecular transition to the slip flow traveling downstream. Two different numerical methods are used in this analysis: the first one is a continuum approach in solving the Navier-Stokes equations with slip boundary conditions, and the second one is a stochastic approach through the use of the direct simulation Monte Carlo method. In the experimental study, the inlet pressures are measured for various outlet pressures in the range of 0.1{\sim}4Torr. From the present study, the numerical results of predicting the performance, obtained by both methods, agree well with the experimental data for the range of Knudsen number $Kn{\leq}0.1$ (i.e., the slip flow regime). But the results from the second method only agree with the experimental data for Kn>0.1(i.e., the molecular transition regime)

• Journal of Pharmaceutical Investigation
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• 제29권3호
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• pp.193-203
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• 1999

In order to investigate systematically the steady shear flow properties of aqueous po1y(ethylene oxide) (PEO) solutions having various molecular weights and concentrations, the steady flow viscosity has been measured with a Rheometrics Fluids Spectrometer (RFS II) over a wide range of shear rates. The effects of shear rate, concentration, and molecular weight on the steady shear flow properties were reported in detail from the experimentally measured data, and then the results were interpreted using the concept of a material characteristic time. In addition, some flow models describing the non-Newtonian behavior (shear-thinning characteristics) of polymeric liquids were employed to make a quantitative evaluation of the steady flow behavior, and the applicability of these models was examined by calculating the various material parameters. Main results obtained from this study can be summarized as follows: (1) At low shear rates, aqueous PEO solutions show a Newtonian viscous behavior which is independent of shear rate. At shear rate region higher than a critical shear rate, however, they exhibit a shear-thinning behavior, demonstrating a decrease in steady flow viscosity with increasing shear rate. (2) As an increase in concentration and/or molecular weight, the zero-shear viscosity is increased while the Newtonian viscous region becomes narrower. Moreover, the critical shear rate at which the transition from the Newtonian to shear-thinning behavior occurs is decreased, and the shear-thinning nature becomes more remarkable. (3) Aqueous PEO solutions show a Newtonian viscous behavior at shear rate range lower than the inverse value of a characteristic time $1/{\lambda}_E$, while they exhibit a shear-thinning behavior at shear rate range higher than $1/{\lambda}_E$. For aqueous PEO solutions having a broad molecular weight distribution, the inverse value of a characteristic time is not quantitatively equivalent to the critical shear rate, but the power-law relationship holds between the two quantities. (4) The Cross, Carreau, and Carreau-Yasuda models are all applicable to describe the steady flow behavior of aqueous PEO solutions. Among these models, the Carreau-Yasuda model has the best validity.

• Biotechnology and Bioprocess Engineering:BBE
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• 제8권2호
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• pp.64-75
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• 2003

Aptamers are functional nucleic acids that can specially bind to proteins, peptides, amino acids. nucleotides, drugs, vitamins and other organic and inorganic compounds. The aptamers are identified from random DNA or RNA libraries by a SELEX (systematic evolution of ligands by exponential amplification) process. As aptamers have the advantage, and potential ability to be released from the limitations of antibodies, they are attractive to a wide range of therapeutic and diagnostic applications. Aptamers, with a high-affinity and specificity, could fulfil molecular the recognition needs of various fields in biotechnology. In this work, we reviewed some aptamer Selection techniques, properties, medical applications of their molecules and their biotechnological applications, such as ELONA (enzyme linked oligonucleotide assay), flow cytometry, biosensors, electrophoresis, chromatography and microarrays.

• 한국환경과학회지
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• 제22권4호
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• pp.407-413
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• 2013

The flow of sewage has been studied for hundreds of years. Reducing drag in pipes can allow sewer to be removed easily and quickly. Drag reduction is not only a macroscale issue. Physical and chemical properties of the nano-scale can affect flow at the macroscopic scale. In this paper the predictability of hydrophobicity at the nano-scale is studied. Molecular dynamics simulations were used to calculate the range of contact angles of water droplets in equilibrium on a pillared graphite surface. It was found that at a pillar height of two graphite layers there was the largest range of contact angles. It is observed that at this height the droplet begins to transition from the Wenzel state to the Cassie-Baxter state. Surfaces with larger pillar heights have much larger contact angles corresponding to a more hydrophobic surface. Silicon dioxide was also simulated in the water droplet. The contaminant slight decreased the contact angle of the water droplet.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2010년도 제39회 하계학술대회 초록집
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• pp.18-18
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• 2010

Methods of the characteristics evaluation of turbo-molecular pumps (TMP) are well-defined in the international measurement standards such as ISO, PNEUROP, DIN, JIS, and AVS. The Vacuum Center in the Korea Research Institute of Standards and Science has recently designed, constructed, and established the integrated characteristics evaluation system of TMPs based on the international documents by continuously pursuing and acquiring the reliable international credibility through measurement perfection. The measurement of TMP pumping speed is normally performed with the throughput and orifice methods dependent on the mass flow regions. However, in the UHV range of the molecular flow region, the high uncertainties of the gauges, mass flow rates, and conductance are too critical to precisely accumulate reliable data. With UHV gauges of uncertainties less than 15% and a calculated conductance of the orifice, about 35% of pumping speed uncertainties are experimentally derived in the pressure range of less than $10^{-6}$ mbar. In order to solve the uncertainty problems of pumping speeds in the UHV range, we introduced an SRG with 1% accuracy and a constant volume flow meter (CVFM) to measure the finite mass flow rates down to $10^{-3}$ mbar-L/s with 3% uncertainty for the throughput method. In this way we have performed the measurement of pumping speed down to less than $10^{-6}$ mbar with an uncertainty of 6% for a 1000 L/s TMP. In this article we suggest that the CVFM has an ability to measure the conductance of the orifice experimentally with flowing the known mass through the orifice chambers, so that we may overcome the discontinuity problem encountering during introducing two measurement methods in one pumping speed evaluation sequence.

• 대한기계학회논문집B
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• 제20권11호
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• pp.3620-3629
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• 1996

In the free molecular flow range, the pumping performance of a turbomolecular pump has been predicted by calculation of the transmission probability which employs the integral method and the test particle Monte-Carlo method. Also, new approximate method combining the double stage solutions, so called double-approximation, is presented here. The calculated values of transmission probability for the single stage agree quantitatively with the previous known numerical results. For a six-stage pump, the Monte-Carlo method is employed to calculate the overall transmission probability for the entire set of blade rows. When the results of the approximate method combining the single stage solutions are compared with those of the Monte-Carlo method at dimensionless blade velocity ratio C=0.4, the previous known approximate method overestimates as much as 34% than does the Monte-Carlo method. But, the new approximate method gives more accurate results, whose relative error is 10% compared to the Monte-Carlo method, than does the previous approximate method.