• Title/Summary/Keyword: Molecular Communication

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Photochemical synthesis of diphenylphenanthrenes, and the photophysical properties studied by emission and transient absorption measurements

  • Yamaji, Minoru;Hakoda, Yuuma;Horimoto, Ami;Okamoto, Hideki
    • Rapid Communication in Photoscience
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    • v.3 no.4
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    • pp.73-75
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    • 2014
  • Novel diphenylphenanthrenes (DPPs) were prepared by a photocyclization method, and the substituent effects of the phenyl groups on the photophysical properties of the phenanthrene chromophore were investigated based on measurements of fluorescence yields, lifetimes, and transient absorption. Fluorescence activities in DPPs are increased by introducing phenyl rings that can enhance the transition moment along the short axis of the phenanthrene skeleton. Intersystem crossing from the fluorescent states to the triplet manifolds is shown to be operative through the triplet-triplet absorption spectra obtained by laser photolysis techniques.

The Rheological Properties of Printing Ink and its printability with the Molecular Weight of Rosin Modified Phenol Resin (로진 변성 페놀 수지의 분자량 변화에 따른 인쇄 잉크의 유변학적 특성과 인쇄적성에 관한 연구)

  • Lee, Kyu-Il;Kim, Sung-Bin
    • Proceedings of the Korean Printing Society Conference
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    • 2007.11a
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    • pp.1-12
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    • 2007
  • The rheological properties of an ink relate to its performance on the press and to the printing quality. So it is necessary to analyze the relationship between printability and the rheological properties of ink. Transfer rate of ink is one of the important factor deciding print quality. And it is concerned with rheological properties of ink. Thus, in this study, according to the molecular weight of rosin modified phenolic resin the rheological properties of ink were measured by rotational rheometer and then transfer equation of ink, density and gloss were mesured in order to examine the printability of ink.

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Photocatalytic Epoxidation of Olefins Using Molecular O2 by TiO2 Incorporated in Hydrophobic Y Zeolite

  • Kuwahara, Yasutaka;Magatani, Yasuhiro;Yamashita, Hiromi
    • Rapid Communication in Photoscience
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    • v.4 no.1
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    • pp.19-21
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    • 2015
  • Zeolite is an ideal host material for encapsulating nano-size metal catalyst species because of its defined microporous structure, prominent adsorption/condensation properties, high surface area, chemical/thermal stability, and transparency to light. In this study, $TiO_2$ photocatalyst was incorporated in highly hydrophobic Y zeolite and its photocatalytic activity was examined in the photocatalytic oxidation of olefins under UV-light irradiation using molecular oxygen as an oxygen source. $TiO_2$ nanoparticles incorporated in hydrophobic Y zeolite exhibited a markedly enhanced photocatalytic activity compared with bare $TiO_2$ owing to its excellent affinity toward organic moieties, which facilitates the mass transfer of organic substrates and allows them to efficiently access to the neighboring active $TiO_2$ surface.

Development of Hepatitis C Virus (HCV) Genome-Targeting Hammerhead Ribozyme Which Activity Can Be Allosterically Regulated by HCV NS5B RNA Replicase (C형 간염바이러스(HCV)의 NS5B RNA Replicase에 의해 그 활성이 조절되는 HCV지놈 표적 Hammerhead 리보자임 개발)

  • Lee, Chang-Ho;Lee, Seong-Wook
    • Korean Journal of Microbiology
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    • v.43 no.3
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    • pp.159-165
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    • 2007
  • For the development of basic genetic materials for specific and effective therapeutic approach to suppress multiplication of hepatitis C virus (HCV), HCV internal ribosome entry site (IRES)-targeting hammerhead ribozyme which activity is allosterically regulated by HCV regulatory protein, NS5B RNA replicase, was developed. The ribozyme targeted most effectively to +382 nucleotide (nt) site of HCV IRES RNA. The allosteric ribozyme was designed to be composed of sequence of RNA aptamer to HCV NS5B, communication module sequence which can transfer structural transition for inducing ribozyme activity upon binding NS5B to the aptamer, and sequence of ribozyme targeting +382 nt of HCV IRES. Noticeably, we employed in vitro selection technology to identify the most appropriate communication module sequence which can induce ribozyme activity depending on the US5B protein. We demonstrated that the ribozyme was nonfunctional either in the absence of any proteins or in the presence of control bovine serum albumin. In sharp contrast, the allosteric ribozyme can induce activity of cleavage reaction with HCV IRES RNA in the presence of the HCV NS5B protein. This allosteric ribozyme can be used as lead compound for specific and effective anti-HCV agent, tool for highthroughput screening to isolate lead chemicals for HCV therapeutics, and ligand for biosensor system for HCV diagnosis.

Inferring Transcriptional Interactions and Regulator Activities from Experimental Data

  • Wang, Rui-Sheng;Zhang, Xiang-Sun;Chen, Luonan
    • Molecules and Cells
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    • v.24 no.3
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    • pp.307-315
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    • 2007
  • Gene regulation is a fundamental process in biological systems, where transcription factors (TFs) play crucial roles. Inferring transcriptional interactions between TFs and their target genes has utmost importance for understanding the complex regulatory mechanisms in cellular systems. On one hand, with the rapid progress of various high-throughput experiment techniques, more and more biological data become available, which makes it possible to quantitatively study gene regulation in a systematic manner. On the other hand, transcription regulation is a complex biological process mediated by many events such as post-translational modifications, degradation, and competitive binding of multiple TFs. In this review, with a particular emphasis on computational methods, we report the recent advances of the research topics related to transcriptional regulatory networks, including how to infer transcriptional interactions, reveal combinatorial regulation mechanisms, and reconstruct TF activity profiles.

CRT Color Transform to CIELab Color System using RGB Image Data (RGB 화상테이터를 이용한 CRT 표현색의 CIELab 표색계로의 변화에 관한 연구)

  • 안석출
    • Journal of the Korean Graphic Arts Communication Society
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    • v.13 no.1
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    • pp.73-91
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    • 1995
  • Spectroscopic and Photoelectric Characteristics in the Cyanine and Merocyanine Dye according to systematically change of their structures were experimentally discussed. As result, in solution, Hetero atoms(X) of Cyanine and Merocyanine dye were participated in resonance X of d obital rather than X of pobital,effected in resonance and contributed in extension of conjugated system. in solid film,new spectra,called eximer-fluorenscence,were appeared in 3-dimensional fluorenscence of high density of Cyanine dye but not of Merocyanine. The activational energy of conductivity in Merocyanine dye was lower than in cyanine, an the contrary,the drift mobility was higher and the former in photoelectric characteristics was more effec-tive than the latter. In this paper,authors invertigated the changes of dye structure by molecular obital method to confirm the results of spectroscopic and photoelectric characteristics in the Cyanine and Merocyanine Dye acco-rding to systematically cally change of their structure, and counted total energy on dihedral angle and dipol miments if dyes in S0 and S1.

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A Study on the Measurement of Quantity of Light and Resolving Power of a Hand-made Lens (실험 렌즈의 광량과 해상력 측정)

  • 강현덕
    • Journal of the Korean Graphic Arts Communication Society
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    • v.14 no.1
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    • pp.89-114
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    • 1996
  • Liquid crystal-polymer composite(LCPC) films consisting of a continuous LC phase embedded in a three-dimensional network of polymer matrix are formed by photopolymerization-induced phase separ on. The LCPC films are switched from a light-scattering stats to a highly transparent stats on the application of electric fields. Since the alignment of LC molecular determines the electro-optical properties of films, the requirement for good contrast is to generate the nematic phase at high concentration. On the other hand, the concentration of UV-curable monomer must be increased above some critical value to from the flexible matrix of unbounded polymer. The mixing ratio of LC and UV-curable monomer affects the electro-optical and viscoelastic properties of LCPD films in two opposing ways. By controlling the phase separation process, at an LC fraction of 0.7, the maximum performance of LCPC films has been achieved, the response time of which is 2ms on the application of electric fields.

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The effect of Several Pulp properties and freeness treated with different sized cellulase (섬유소 분해효소의 분자량에 따른 조합처리가 종이의 강도 변화 및 표면 변화에 미치는 영향)

  • 김병헌
    • Journal of the Korean Graphic Arts Communication Society
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    • v.19 no.1
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    • pp.75-85
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    • 2001
  • This study confirmed different results according to the molecular weight and pore properties of treated pulp. In this study the pre-treated enzyme material was increasing the beating speed compared with non-treated one. And it was observed that the change of freeness according to the combination ratio depended upon the pores size of pulp and that fibers became flexible owing to the physical deformation of fibers themselves through pre-treated enzyme increasing the flexibility of fibers to increase the contact area of fiber and thus resulting in the increase of specific surface area, the increase of fiber bonding strength and the increase of beating speed.

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Mapping Cellular Coordinates through Advances in Spatial Transcriptomics Technology

  • Teves, Joji Marie;Won, Kyoung Jae
    • Molecules and Cells
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    • v.43 no.7
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    • pp.591-599
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    • 2020
  • Complex cell-to-cell communication underlies the basic processes essential for homeostasis in the given tissue architecture. Obtaining quantitative gene-expression of cells in their native context has significantly advanced through single-cell RNA sequencing technologies along with mechanical and enzymatic tissue manipulation. This approach, however, is largely reliant on the physical dissociation of individual cells from the tissue, thus, resulting in a library with unaccounted positional information. To overcome this, positional information can be obtained by integrating imaging and positional barcoding. Collectively, spatial transcriptomics strategies provide tissue architecture-dependent as well as position-dependent cellular functions. This review discusses the current technologies for spatial transcriptomics ranging from the methods combining mechanical dissociation and single-cell RNA sequencing to computational spatial re-mapping.

A Study on the Physical Properties according to Varnish Cooking Conditions of Phenolic Modified Rosin Ester (로진변성 페놀수지의 Varnish 제조조건에 따른 물성 변화에 관한 연구)

  • Jung, Soon-Kie;Kim, Sung-Bin
    • Journal of the Korean Graphic Arts Communication Society
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    • v.24 no.2
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    • pp.11-24
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    • 2006
  • The Lithographic ink is composed of pigment, vehicle and additives. In especially, the vehicle is the most important element and consist of vegetable oils, mineral oils and resins. Varnishes have to resist certain forms of chemical and physical attack during ink manufacturing process and printing process So this varnish cooking is very important. In this paper, effects of cooking conditions of varnish using phenolic modified rosin ester on physical properties of the vehicle were studied. The varnish cooked according to temperature and time were compared in order of average molecular weight by the GPC method. and the rheological properties were found by rotational rheometer. And the emulsion behavior were compared by high speed emulsification tester which were set on 1200 rpm and $40^{\circ}C$ temperature (Novomatics Lithotronic). We displayed viscosity against tack(Inkometer Thwing-Albert M-106) by diagram.

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