• 대한의용생체공학회:의공학회지
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• 제31권1호
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• pp.81-86
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• 2010

Laser irradiation is known to affect various tissues such as skin, bone, nerve, and skeletal muscle. Laser irradiation promotes ATP synthesis, facilitates wound healing, and stimulates cell proliferation and angiogenesis. In skeletal muscle, laser irradiation is related to the proliferation of skeletal muscle satellite cells. Normal skeletal muscle contains remodeling capacity from myogenic cells that are derived from mononuclear satellite cells. Their processes are activated by the expression of genes related with myogenesis such as muscle-specific transcription factors (MyoD and Myf5) and VEGF (vascular endothelial growth factor). In this study, we hypothesized that laser irradiation would enhance and regulate muscle cell proliferation and regeneration through modulation of the gene expressions related with the differentiation of skeletal muscle satellite cells. $C_2C_{12}$ myoblastic cells were exposed to continuous/non-continuous laser irradiation (660nm/808nm) for 10 minutes daily for either 1 day or 5 days. After laser irradiation, cell proliferation and gene expression (MyoD, Myf5, VEGF) were quantified. Continuous 660nm laser irradiation significantly increased cell proliferation and gene expression compared to control, continuous 808nm laser irradiation, and non-continuous 660nm laser irradiation groups. These results indicate that continuous 660nm laser irradiation can be applied to the treatment and regeneration of skeletal muscle tissue.

• 한방비만학회지
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• 제9권1호
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• pp.1-14
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• 2009

Complex microbial communities play an important role in the human health and co-evolved with human in the form of symbiosis. Many literatures provide new evidences that the increased prevalence of obesity cannot be attributed solely to changes in the human genome, nutritional habits, or reduction of physical activity in our daily lives. The intestinal flora was recently proposed as an environmental factor responsible for the control of body weight and energy metabolism. A number of studies suggest that the modulation of gut microbiota affects host metabolism and has an impact on energy storage and demonstrated a role for the gut microbiota in weight gain, fat increase, and insulin resistance. Variations in microbiota composition are found in obese humans and mice and the microbiota from an obese mouse confers an obese phenotype when transferred to an axenic mouse. As well, the gut microbial flora plays a role in converting nutrients into calories. Specific strategies for modifying gut microbiota may be a useful means to treat or prevent obesity. Dietary modulations of gut microbiota with a view to increasing bifidobacteria have demonstrated to reduce endotoxemia and improve metabolic diseases such as obesity. The fermentation of medicinal herbs is intended to exert a favorable influence on digestability, bioavailability and pharmacological activity of herbal extract. Therefore we also expect that the fermented herbal extracts may open up a new area to treat obesity through modulating gut microbiota.

• 대한전자공학회논문지SD
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• 제45권12호
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• pp.47-56
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• 2008

최근 대두되고 있는 유비쿼터스(ubiquitous) 환경과 같이 어느 곳, 어느 때, 누구든지 원하는 정보를 획득할 수 있는 무선 네트워킹의 구축을 위해서는 반드시 필요한 기술로 RFID 시스템은 기본적으로 정보를 저장하고 있는 태그(tag, transponder)를 아이템에 부착하고, 리더(reader)는 라디오(radio) 주파수를 이용하여 태그에 저장하고 있는 고유 번호 (identification number) 등의 정보를 읽어 낸다. 본 논문은 FeRAM을 내장한 EPCglobal UHF 태그 칩 설계에 관한 내용이다. 태그 칩의 구성은 메모리, 아날로그, 디지털 3부분으로 나눌 수 있는데 디지털 부분에서 전력 소모를 줄이는 방법으로 순차적인 데이터 처리 구조에 게이티드 클록(gated clock)을 사용하여 해당 모듈의 동작에 의한 동적 전력 소모량을 최대한 줄였다. 태그는 $0.25{\mu}m$ CMOS 공정을 사용하여, 잔류 분극 값이 $32{\mu}C/cm^2$, 3V 인가전압에서 $2.5{\times}10^{-6}A/cm^2$ 누설 전류를 가진 ferrocapacitance를 사용하고 있다. 태그의 면적은 절단선을 포함하여 $750{\mu}m{\times}750{\mu}m$이며, 태그 소모 전력은 인가전압 2V에서 약 $17.8{\mu}W$이다.

• 한국재료학회지
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• 제23권4호
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• pp.215-218
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• 2013

Vanadium dioxide ($VO_2$) is an attractive material for smart window applications where the transmittance of light can be automatically modulated from a transparent state to an opaque state at the critical temperature of ${\sim}68^{\circ}C$. Meanwhile, F : $SnO_2$ (F-doped $SnO_2$, FTO) glass is a transparent conductive oxide material that is widely used in solar-energy-related applications because of its excellent optical and electrical properties. Relatively high transmittance and low emissivity have been obtained for FTO-coated glasses. Tunable transmittance corresponding to ambient temperature and low emissivity can be expected from $VO_2$ films deposited onto FTO glasses. In this study, FTO glasses were applied for the deposition of $VO_2$ thin films by pulsed DC magnetron sputtering. $VO_2$ thin films were also deposited on a Pyrex substrate for comparison. To decrease the phase transition temperature of $VO_2$, tungsten-doped $VO_2$ films were also deposited onto FTO glasses. The visible transmittance of $VO_2$/FTO was higher than that of $VO_2$/pyrex due to the increased crystallinity of the $VO_2$ thin film deposited on FTO and decreased interface reflection. Although the solar transmittance modulation of $VO_2$/FTO was lower than that of $VO_2$/pyrex, room temperature solar transmittance of $VO_2$/FTO was lower than that of $VO_2$/pyrex, which is advantageous for reflecting solar heat energy in summer.

• 전기전자학회논문지
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• 제24권3호
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• pp.838-844
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• 2020

본 논문에서는 검출과 복호가 결합된 효율적인 비터비 알고리즘 (joint Viterbi detection and decoding (JVDD))의 저복잡도 하드웨어 설계 및 구현 결과를 제시한다. 길쌈부호화된 GMSK 신호가 BLE 5.0 표준으로 채택 되어있으므로 검출과 복호를 위해 두개의 비터비 프로세서가 필요하다. 그러나, 제안된 JVDD 알고리즘은 GMSK에 의해서 유발된 심볼간의 간섭정보(ISI : inter-symbol interference)가 반영된 가지 메트릭 (branch metric)을 사용하여 단지 하나의 비터비 만을 사용하여도 검출과 복호 수행이 가능하며, 성능 저하 없이 복잡도 감소가 가능하다. JVDD 알고리즘을 적용한 BLE 비터비 복호기의 하드웨어 구현을 위해 효율적인 구조 설계가 수행되었다. 제안된 구조는 1 클럭 사이클 동안 복호를 완료할 수 있기 때문에 저지연 및 저면적 구현이 가능하다. 제안된 비터비 복호기는 Verilog-HDL을 이용하여 RTL 설계되었고, GF 55nm 공정을 활용하여 논리합성 및 구현되었다. 합성결과 12K 게이트 수를 포함하였으며 메모리 유닛 및 초기 지연시간은 MSE (modified state exchange) 대비 33% 감소 가능함을 확인하였다.

• 대한전기학회논문지:시스템및제어부문D
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• 제55권2호
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• pp.68-71
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• 2006

Active thermography has been used for several years in the field of remote non-destructive testing. It provides thermal images for remote detection and imaging of damages. Also, it is based on propagation and reflection of thermal waves which are launched from the surface into the inspected component by absorption of modulated radiation. For energy deposition, it use external heat sources (e.g., halogen lamp or convective heating) or internal heat generation (e.g., microwaves, eddy current, or elastic wave). Among the external heat sources, the ultrasound is generally used for energy deposition because of defect selective heating up. The heat source generating a thermal wave is provided by the defect itself due to the attenuation of amplitude modulated ultrasound. A defect causes locally enhanced losses and consequently selective heating up. Therefore amplitude modulation of the injected ultrasonic wave turns a defect into a thermal wave transmitter whose signal is detected at the surface by thermal infrared camera. This way ultrasound thermography(UT) allows for selective defect detection which enhances the probability of defect detection in the presence of complicated intact structures. In this paper the applicability of UT for fast defect detection is described. Examples are presented showing the detection of defects in PCB material. Measurements are performed on various kinds of typical defects in PCB materials (both Cu metal and non-metal epoxy). The obtained thermal image reveals area of defect in row of thick epoxy material and PCB.

• The Korean Journal of Physiology and Pharmacology
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• 제5권5호
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• pp.423-431
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• 2001

Some recent investigations revealed that vasodilatory action of adenosine is mainly not mediated by surface A2 receptor and suggested the existence of an intracellular action site. In the present study, we tried to differentiate intracellular from extracellular site of adenosine action in the regulation of coronary flow. In perfused rabbit hearts, concentration-response curve of coronary flow to exogenous adenosine was constructed in the presence or absence of dipyridamole, an inhibitor of transmembrane purine transport. Inhibition of cellular adenosine uptake by dipyridamole suppressed the increase of flow rate while enhancing the decrease in heart rate induced by exogenous adenosine. In another series of experiments, perfused rabbit hearts were subjected to energy deprivation in order to increase the production of endogenous adenosine. Energy deprivation along with dipyridamole administration resulted in higher coronary flow rate. Lower perfusate adenosine concentration was observed along with higher tissue adenosine content in this group. These results implied that coronary flow rate is determined not by interstitial adenosine concentration but by intracellular activity of adenosine. To confirm the effects of dypiridamole in vivo, direct measurement of interstitial adenosine concentration by mycrodialysis along with the assay of intracellular adenosine content was performed after intranenous dipyridamole administration. After dipyridamole infusion, intracellular adenosine content was markedly increased while interstitial adenosine concentration was not altered. In another series of experiments, the right shift of concentration-response curve of adenosine-induced vasodilation by 8-phenyltheophilline, a representative adenosine receptor antagonist, was mostly abolished by prior administration of prazosin, indicating that the influence of 8-PT on the adenosine action is not attributed to the inhibition of A2 receptor but related to the suppression of ${\alpha}-adrenoceptor$ activation. From these results, we concluded that adenosine acts intracellularly to regulate the coronary blood flow.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.314-314
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• 2012

The dilute magnetic semiconductors (DMS) have been developed to multi-functional electro-magnetic devices. Specially, the Si based DMS formed by ion implantation have strong advantages to improve magnetic properties because of the controllable effects of carrier concentration on ferromagnetism. In this study, we investigated the deep level states of Fe- and Co-ions implanted Si wafer during rapid thermal annealing (RTA) process. The p-type Si (100) wafers with hole concentration of $1{\times}10^{16}cm^{-3}$ were uniformly implanted by Fe and Co ions at a dose of $1{\times}10^{16}cm^{-2}$ with an energy of 60 keV. After RTA process at temperature ranges of $500{\sim}900^{\circ}C$ for 5 min in nitrogen ambient, the Au electrodes with thickness of 100 nm were deposited to fabricate a Schottky contact by thermal evaporator. The surface morphology, the crystal structure, and the defect state for Fe- and Co- ion implanted p-type Si wafers were investigated by an atomic force microscopy, a x-ray diffraction, and a deep level transient spectroscopy, respectively. Finally, we will discuss the physical relationship between the electrical properties and the variation of defect states for Fe- and Co-ions implanted Si wafer after RTA.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.427-427
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• 2012

Ferroelectric-gate field effect transistor based memory using a nanowire as a conducting channel offers exceptional advantages over conventional memory devices, like small cell size, low-voltage operation, low power consumption, fast programming/erase speed and non-volatility. We successfully fabricated ferroelectric nonvolatile memory devices using both n-type and p-type Si nanowires coated with organic ferroelectric poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] via a low temperature fabrication process. The devices performance was carefully characterized in terms of their electrical transport, retention time and endurance test. Our p-type Si NW ferroelectric memory devices exhibit excellent memory characteristics with a large modulation in channel conductance between ON and OFF states exceeding $10^5$; long retention time of over $5{\times}10^4$ sec and high endurance of over 105 programming cycles while maintaining ON/OFF ratio higher $10^3$. This result offers a viable way to fabricate a high performance high-density nonvolatile memory device using a low temperature fabrication processing technique, which makes it suitable for flexible electronics.

• Journal of Communications and Networks
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• 제16권4호
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• pp.397-406
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• 2014

Radio frequency (RF) jamming is a denial of service attack targeted at wireless networks. In resource-hungry scenarios with constant traffic demand, jamming can create connectivity problems and seriously affect communication. Therefore, the vulnerabilities of wireless networks must be studied. In this study, we investigate a particular type of RF jamming that exploits the semantics of physical (PHY) and medium access control (MAC) layer protocols. This can be extended to any wireless communication network whose protocol characteristics and operating frequencies are known to the attacker. We propose two efficient jamming techniques: A low-data-rate random jamming and a shot-noise based protocol-aware RF jamming. Both techniques use shot-noise pulses to disrupt ongoing transmission ensuring they are energy efficient, and they significantly reduce the detection probability of the jammer. Further, we derived the tight upper bound on the duration and the number of shot-noise pulses for Wi-Fi, GSM, and WiMax networks. The proposed model takes consider the channel access mechanism employed at the MAC layer, data transmission rate, PHY/MAC layer modulation and channel coding schemes. Moreover, we analyze the effect of different packet sizes on the proposed jamming methodologies. The proposed jamming attack models have been experimentally evaluated for 802.11b networks on an actual testbed environment by transmitting data packets of varying sizes. The achieved results clearly demonstrate a considerable increase in the overall jamming efficiency of the proposed protocol-aware jammer in terms of packet delivery ratio, energy expenditure and detection probabilities over contemporary jamming methods provided in the literature.