• 제목/요약/키워드: Modern disease

검색결과 380건 처리시간 0.037초

흉부외과환자 임상정보의 전산화 방법에 대한 고찰;데이터베이스 파일(DBF) 구조의 표준화및 코딩화 방안에 대하여 (The Evaluation of Method for Computerization of Clinical Informations of the Patients of the Department of Thoracic and Cardiovascular Surgery - About the practical method of coding and standardization of the structure of the database file(DBF) -)

  • 송우철;김병주;홍기우
    • Journal of Chest Surgery
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    • 제25권10호
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    • pp.989-1000
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    • 1992
  • The concepts of modern type computer are so called "General purpose, stored program and digital computer" that is proposed by Charles Babbage. ENIAC, the initial operational electronic digital computer model, was produced in 1946. During the last 50 years, an epoch-making development of the personal computer was marked. The computerization of all levels of society is going on and also computerization of the general hospital and medical college is developing. But patient data management system for clinician is not used generally. We suggest the use of computer aided data management application programs for the clinical informations of the patients of the Department of Thoracic and Cardiovascular Surgery for better management and to make best of medical informations, to co-operate with the current of this times, and to prepare against the Hospital Information Systems[HIS], actively. Also, we suggest to standardize the format and structure of database files to store the clinical data of the patients By standardization of the database files, we can integrate and relate the data of the individual department or hospital, build up the regional or national statistics of the patients easily, and promote the generation of application programs. The medical network by the communication and computer would be utilized to collect the database files. And finally, we suggest the use of code system to input and search the informations about the diagnosis and operation such as the code system of International Classfication of Disease[WHO] and the table of the classfication of operation of the Ministry of Health and Social Affairs, Korea. In this article, we tried to show the new standards, the essential items for computerization of clinical informations of the patients of the Department of Thoracic and Cardiovascular Surgery.r Surgery.

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Isolation of Antifungal Compound and Biocontrol Potential of Lysobacter antibioticus HS124 against Fusarium Crown Rot of Wheat

  • Monkhung, Sararat;Kim, Yun-Tae;Lee, Yong-Seong;Cho, Jeong-Yong;Moon, Jae-Hak;Kim, Kil-Yong
    • 한국토양비료학회지
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    • 제49권4호
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    • pp.393-400
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    • 2016
  • Fusarium graminearum is the main cause of substantial economic loss in wheat production. The aim of this study is to investigate biocontrol potential of Lysobacter antibioticus HS124 against F. graminearum and to purify an antifungal compound. In preliminary study, n-butanol crude extract revealed destructive alterations in the hyphal morphology of F. graminearum and almost degraded with $1,000{\mu}g\;mL^{-1}$ concentration. For further study, the antifungal compound extracted from the n-butanol crude extract of L. antibioticus HS124 was identified as N-Butyl-tetrahydro-5-oxofuran-2-carboxamide ($C_9H_{16}NO_3$) using NMR ($^1H-NMR$, $^{13}C-NMR$, $^1H-^1H\;COSY$, HMBC, and HMQC), and HR-ESI-MS analysis. To our knowledge, N-Butyl-tetrahydro-5-oxofuran-2-carboxamide may be a novel compound with molecular weight of 186.1130. The minimum inhibitory concentration value of antifungal compound was $62.5{\mu}g\;mL^{-1}$ against F. graminearum. In an in vivo pot experiment, crown rot disease from F. graminearum was inhibited when wheat seeds were treated with both HS124 culture and F. graminearum. Growth of wheat seedling was enhanced by treatment of HS124 compared to control. Our results suggest that L. antibioticus HS124 characterized in this study could be successfully used to control F. graminearum and could be used as an alternative to chemical fungicides in modern agriculture.

$\ll$의학입문(醫學入門).장부조분(臟腑條分)$\gg$간장(肝臟)에 작용하는 약물(藥物)에 관한 연구(硏究) (A study on the Medicines Effected on the Liver in the 'Bowel-Viscus Classification' of An Introduction to Medical Science)

  • 금경수;임양순
    • 대한한의정보학회지
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    • 제11권1호
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    • pp.26-47
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    • 2005
  • In this dissertation, I will focus on the channel entry, the effect, and the treatment throughout books of oriental medicine from ancient to modern in order to classify the medicines of the liver as main or supplementary organ. The results are as follows: 1. The kinds of the medicines of working of the liver(本臟) were 29, which were Amydae carapax(鱉甲), Chrysanthemi Flos(菊花), Cassiae Torae Semen(草決明), Plantaginis Semen(車前子), Scirpi Seu Sparganii(三稜), Ulmi Pasta Semen(蕪荑), Cinnamomi Cortex(肉桂), Fraxini Cortex(秦皮), Chaenomelis Fructus(木果), Corii Asini Colla(阿膠), Chuanxiong Rhizoma(川芎), Adenophorae Radix(沙蔘), Coicis Semen(薏苡仁), Acanthopanacis Cortex(五加皮), Zizyphi Spinosae Semen(酸棗仁), Picrorrhizae Rhizoma(胡黃連), Gentianae Radix(草龍膽), Citri Reticulatae Virdie Pericarpium(靑皮), Paeoniae Alba Radix(白芍藥), Paeoniae Rubra Radix(赤芍藥), Bupleuri Radix(柴胡), Peucedani Radix(前胡), Naturalis Indigo(靑黛), Citrus unshiu(橘葉), Rhinocerotis Cornu(犀角), Aucklandiae Radix(木香), Polygonati Odorati Rhizoma, Farfarae Flos(款冬花), Evodiae Fructus(吳茱萸), Citri Reticulatae Pericarpium(陳皮) . 2. The kinds of the medicines of working of other viscera(他臟) were 7, which were Astragaliadix(黃耆), Ginseng Radix(人蔘), pinelliae Rhizoma(半夏), Myristicae Semen, Euryales Semen, Arecae Semen, Piperis Longi Fructus. 3. Medicines, effected on the heart functioned through any other viscera are as follows: Arecae Semen works to treat Spleen Gi Entering the Liver(脾氣入肝), Piperis Longi Fructus, pinelliae Rhizoma(半夏), Euryales Semen and Myristicae Semen operate to treat Spleen Cold Entering the Liver(脾冷入肝), Astragali Radix(黃耆) and Ginseng Radix(人蔘) work to treat Spleen Vacuity Entering the Liver(脾虛入肝). In the study of concerning the medicines effected on the liver, It is considered that it dedicated to development of the medicines related to the disease of the liver and making efficient use of the medicines.

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이태리 요리의 선호도 분석 및 운영개선방안에 관한 연구 (A Study on preference of Italian Cuisine)

  • 정진우
    • 한국조리학회지
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    • 제2권
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    • pp.169-181
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    • 1996
  • Today we are inclined to dine out more frequently according as the national income is increased and Women enter into the Social life, 'This tendency results in the universality of foodculture and the food made of fresh food stuff as well as the Pollution-free food is preferable as everyone warits to eat natural food or health food and escapes from the pollution. Moreover we have socail problems like fatress and adult disease which result from the small amount of activity or the food with high calory and high gat. under this circumstance. the most adeguate food seems to be Italian good. It stand in the spottight of food world and is most preferable for everyone today. The sphere of food and beverage has a low value-added-rate compartry to the high increasing rate of customers and profit, so, the efficient managing method for the cost of food and beverage and the operating skill in the kitchen are the principal factors leading to success or failure. Therefore, this research is to show some remedies as follows, pointing out the operating problems of an selected Italian restaurant at the top class hotel. First, most Italian restaurant at the hotel are located in the best place and investing the big capital, But they are open for only 8 hours through a day. This should be improved not to bring a enormous loss to the hotel The brealefast menus such as vegetables or fish food, pizza and pasta which modern man can easily enjoy should be developed open the restaurants for morning gours. Second, the business hours are not made continously. As a result, all the emplyees should stay in the company all day long without taking any advantage of the losed time, This will be the loss for both the company and the employees, By veloping the morning menus, employees shald be classified into morning and afternoon staffs and the opening and closing hour at 3 and 6 O'clock should be used so that minimum number of employees may operate the company. Third, the characteristic of Italian food is in the use of fresh food stuff, The proper purchase of food stuff and the simple distributing system will help Italian restaurant show its character istcc as a hzgh-grade restaurant. Fourth, the most popular Italian food such as pizza or pasta should be market with Priority.

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Pre-Natal Epigenetic Influences on Acute and Chronic Diseases Later in Life, such as Cancer: Global Health Crises Resulting from a Collision of Biological and Cultural Evolution

  • Trosko, James E.
    • Preventive Nutrition and Food Science
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    • 제16권4호
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    • pp.394-407
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    • 2011
  • Better understanding of the complex factors leading to human diseases will be necessary for both long term prevention and for managing short and long-term health problems. The underlying causes, leading to a global health crisis in both acute and chronic diseases, include finite global health care resources for sustained healthy human survival, the population explosion, increased environmental pollution, decreased clean air, water, food distribution, diminishing opportunities for human self-esteem, increased median life span, and the interconnection of infectious and chronic diseases. The transition of our pre-human nutritional requirements for survival to our current culturally-shaped diet has created a biologically-mismatched human dietary experience. While individual genetic, gender, and developmental stage factors contribute to human diseases, various environmental and culturally-determined factors are now contributing to both acute and chronic diseases. The transition from the hunter-gatherer to an agricultural-dependent human being has brought about a global crisis in human health. Initially, early humans ate seasonally-dependent and calorically-restricted foods, during the day, in a "feast or famine" manner. Today, modern humans eat diets of caloric abundance, at all times of the day, with foods of all seasons and from all parts of the world, that have been processed and which have been contaminated by all kinds of factors. No longer can one view, as distinct, infectious agent-related human acute diseases from chronic diseases. Moreover, while dietary and environmental chemicals could, in principle, cause disease pathogenesis by mutagenic and cytotoxic mechanisms, the primary cause is via "epigenetic", or altered gene expression, modifications in the three types of cells (e.g., adult stem; progenitor and terminally-differentiated cells of each organ) during all stages of human development. Even more significantly, alteration in the quantity of adult stem cells during early development by epigenetic chemicals could either increase or decrease the risk to various stem cell-based diseases, such as cancer, later in life. A new concept, the Barker hypothesis, has emerged that indicates pre-natal maternal dietary exposures can now affect diseases later in life. Examples from the studies of the atomic bomb survivors should illustrate this insight.

류머티스 환자 이력 데이터에 기반한 환자 플로우 모니터링 시스템 (Patient Flow Monitoring System based on Rheumatic Patient History Data)

  • 김준우;이상철;박상찬
    • 한국콘텐츠학회논문지
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    • 제14권10호
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    • pp.10-19
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    • 2014
  • 최근 병원에서 수집되는 데이터를 전자적으로 저장, 관리 및 공유하기 위하여 병원정보시스템이 널리 활용되고 있다. 이러한 시스템들은 현대 병원들의 업무 효율성 제고에 크게 기여해왔으나, 건강관리 서비스 제공자들의 의사 결정을 지원하기 위해서는 수집된 환자 관련 데이터를 적절히 가공하고 재사용하는 것이 필요하다. 특히, 본 논문은 만성 질환과 관련된 외래진료과 운영관리를 위한 환자 플로우 모니터링을 제안하고, 이와 관련된 사항들에 대해 토의하고자 한다. 제안하는 시스템은 환자 이력 데이터에 프로세스 마이닝 기법을 적용하여 추출한 표준 프로세스 모형 및 여러 가지 평가 지표들을 시각화하며, 이를 통해 관리자들은 외래진료과의 운영을 평가하고 개선할 수 있다. 본 논문에서는 환자 플로우 모니터링 시스템을 류머티스 진료과에 적용하였으며, 아이패드 기기에 최적화된 프로토타입 시스템을 예시로 보이고자 한다.

울증(鬱證)의 개념 정립에 관한 문헌고찰 (A Review on the Concept Establishment of Stagnation Syndrome)

  • 김상현;최유진;정인철;이미영;양창섭
    • 동의신경정신과학회지
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    • 제31권2호
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    • pp.121-133
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    • 2020
  • Objectives: The purpose of this study was to identify the meanings and characteristic of the stagnation syndrome, a distinctive clinical syndrome in traditional Korean medicine (KM). Methods: The major ancient Oriental medicine literature, including Huangdi neijing (黃帝內經), Danxixinfa (丹溪心法), and Jingyuequanshu (景岳全書) were examined to identify the semantic change of the stagnation syndrome (鬱證). Also, recently published articles about the stagnation syndrome were searched from databases including MEDLINE, CENTRAL, KMBASE, KISS, NDSL, and OASIS. Results: The term of stagnation was originally used to describe not flowing and clogged situations, and the stagnation syndrome appeared as an independent syndrome in Danxixinfa. As the etiology became more sophisticated over time, emotional factors were mentioned for one of the causes of the stagnation syndrome. However, the major causes and symptoms of the stagnation syndrome were somatic factors. Various articles about stagnation were searched, and most of them used "stagnation" as the KM syndrome subtype of disease, some of them referred to the "stagnation syndrome" as an independent syndrome. The recently defined stagnation syndrome commonly shows distinctive symptoms of chest stuffiness, and an obstructing sensation in the throat. Conclusions: The semantic changes and characteristics of the stagnation syndrome were examined through searching ancient and modern literature. The meaning of the stagnation syndrome has evolved over time, and at its center, there are somatic and mental symptoms characterized by stagnation, distinguished from the depressive disorder.

한국 저널에 게재된 기공관련 대조군 임상연구 현황 분석 (Research Trends on the Clinical Studies of Qigong in the Korean Journal)

  • 한창현;권영규;이상남;박지하;안상우
    • 동의생리병리학회지
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    • 제23권2호
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    • pp.319-324
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    • 2009
  • Qigong is one energy-healing intervention used to prevent and cure ailments and to improve health through regular practice. Although qigong -neither itself nor its postulated mechanism of action- are within the paradigm of modern Western medical science, effects on the human body could be possible. This study aims to review the bibliography, biological responses and therapeutic effects of Qigong. In the process, this review will grasp trends in this field of studies and will direct further researches into the right direction. The computerized Korean databases were searched from their respective inceptions up to January 2008. The search terms used were 'qi', 'qigong', 'doin', 'training', 'bioenergy', 'life nurturing' and random or Korean language terms related to qigong. Several specialized journals were also manually searched for relevant articles. Since the 1990s, Qigong papers in the Korean Literature is increased. Clinical research studies are among the most control design study. Research subjects are less patient than the general public. The most common treatment disease was hypertension. The depth study for the each Qigong is needed. Specifically, I think it should be a clinical studies and qualitative research methods for evaluation are needed.

A Study on Environmental Micro-Dust Level Detection and Remote Monitoring of Outdoor Facilities

  • Kim, Seung Kyun;Mariappan, Vinayagam;Cha, Jae Sang
    • International journal of advanced smart convergence
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    • 제9권1호
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    • pp.63-69
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    • 2020
  • The rapid development in modern industrialization pollutant the water and atmospheric air across the globe that have a major impact on the human and livings health. In worldwide, every country government increasing the importance to improve the outdoor air pollution monitoring and control to provide quality of life and prevent the citizens and livings life from hazard disease. We proposed the environmental dust level detection method for outdoor facilities using sensor fusion technology to measure precise micro-dust level and monitor in realtime. In this proposed approach use the camera sensor and commercial dust level sensor data to predict the micro-dust level with data fusion method. The camera sensor based dust level detection uses the optical flow based machine learning method to detect the dust level and then fused with commercial dust level sensor data to predict the precise micro-dust level of the outdoor facilities and send the dust level informations to the outdoor air pollution monitoring system. The proposed method implemented on raspberry pi based open-source hardware with Internet-of-Things (IoT) framework and evaluated the performance of the system in realtime. The experimental results confirm that the proposed micro-dust level detection is precise and reliable in sensing the air dust and pollution, which helps to indicate the change in the air pollution more precisely than the commercial sensor based method in some extent.

Immunopathological Changes in the Brain of Immunosuppressed Mice Experimentally Infected with Toxocara canis

  • Eid, Mohamed M.;El-Kowrany, Samy I.;Othman, Ahmad A.;El Gendy, Dina I.;Saied, Eman M.
    • Parasites, Hosts and Diseases
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    • 제53권1호
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    • pp.51-58
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    • 2015
  • Toxocariasis is a soil-transmitted helminthozoonosis due to infection of humans by larvae of Toxocara canis. The disease could produce cognitive and behavioral disturbances especially in children. Meanwhile, in our modern era, the incidence of immunosuppression has been progressively increasing due to increased incidence of malignancy as well as increased use of immunosuppressive agents. The present study aimed at comparing some of the pathological and immunological alterations in the brain of normal and immunosuppressed mice experimentally infected with T. canis. Therefore, 180 Swiss albino mice were divided into 4 groups including normal (control) group, immunocompetent T. canis-infected group, immunosuppressed group (control), and immunosuppressed infected group. Infected mice were subjected to larval counts in the brain, and the brains from all mice were assessed for histopathological changes, astrogliosis, and IL-5 mRNA expression levels in brain tissues. The results showed that under immunosuppression, there were significant increase in brain larval counts, significant enhancement of reactive gliosis, and significant reduction in IL-5 mRNA expression. All these changes were maximal in the chronic stage of infection. In conclusion, the immunopathological alterations in the brains of infected animals were progressive over time, and were exaggerated under the effect of immunosuppression as did the intensity of cerebral infection.