• Journal of Gastric Cancer
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• 제19권4호
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• pp.375-392
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• 2019

Preoperative chemo- and radiotherapeutic strategies followed by surgery are currently a standard approach for treating locally advanced gastric and esophagogastric junction cancer in Western countries. However, in a large number of cases, the tumor is extremely resistant to these treatments and the patients are exposed to unnecessary toxicity and delayed surgical therapy. The current clinical trials evaluating the combination of preoperative systemic therapies with modern targeted and immunotherapeutic agents represent a unique opportunity for identifying predictive biomarkers of response to select patients that would benefit the most from these treatments. However, it is of utmost importance that these potential biomarkers are corroborated by extensive preclinical and translational research. The aim of this review article is to present the most promising biomarkers of response to classic chemotherapeutic, anti-HER2, antiangiogenic, and immunotherapeutic agents that can be potentially useful for personalized preoperative systemic therapies in gastric cancer patients.

• Clinical and Experimental Reproductive Medicine
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• 제44권4호
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• pp.181-186
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• 2017

With advances in the methods of cancer treatment used in modern medicine, the number of breast cancer survivors has been consistently rising. As the number of women who wish to become pregnant after being diagnosed with breast cancer increases, it is necessary to consider fertility preservation in these patients. However, medical doctors may be unaware of the importance of fertility preservation among cancer patients because most patients do not share their concerns about fertility with their doctors. Considering the time spent choosing and undergoing treatment, an early referral to a reproductive specialist is the best way to prevent a delay in cancer treatment. Since it is not easy to make decisions on matters related to cancer diagnosis and fertility, patients should be provided with enough time for decision-making, and to allow for this, an early referral will provide patients with sufficient time to choose an appropriate method of fertility preservation. The currently available options of fertility preservation for patients with breast cancer include cryopreservation of embryos, oocytes, and ovarian tissue and gonadotropin-releasing hormone agonist treatment before and during chemotherapy. An appropriate method of fertility preservation must be selected through consultations between individual patients and health professionals and analyses of the pros and cons of different options.

• Advances in Traditional Medicine
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• 제4권1호
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• pp.1-8
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• 2004

Ginseng root has been used as a tonic remedy in Traditional Chinese Medicine for centuries. Modern studies have demonstrated that ginseng root has complex components and multiple pharmacological properties. The effects of ginseng leaf, however, are not well known. Recent studies show that compared to ginseng root, ginseng leaf and stem exhibit a higher content of active compositions such as ginsenosides, polysaccharides, triterpene flavonoids, volatile oil, polyacetylenic alcohols, peptides, amino acids and fatty acids. Ginseng leaf possesses multiple pharmacological effects in the central nervous, cardiovascular, growth and metabolism systems. Additionally, the leaf has anti-fatigue, anti-hyperglycemic, anti-oxidant, and anti-aged effects. In general, ginseng leaf is quite safe, but adverse effects may occur if it is abused or is of poor quality. Thus, attention must be paid to dosages, quality, and standardization of ginseng leaf products.

• 대한한의학원전학회지
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• 제32권3호
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• pp.103-130
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• 2019

Objectives : In this paper, the life and medical philosophy of Jo, Heonyeong, a Korean Medical scholar of modern times was studied. Based on his life events and publications, his medical philosophy was examined. Methods : Jo's life tracks were reconstructed based on his books, written contributions, documents on his activities that were collected from newspapers, magazines, papers, etc. In addition, the direction of his Korean Medical research and clinical application as argued by himself was examined. Results : After he himself understood the fundamental principles of Korean Medicine thoroughly, Jo, Heonyeong interpreted the principles of Korean Medicine by means of general scientific methodology along with simple, common knowledge based explanations. He compared Eastern Medicine with Western Medicine and pursued their integration, while making it his objective to have lay people understand medicine and to receive proper medical care and live healthy lives, based on the principles of a righteous government. The reason for his contributions to lay people targeted mediums and writing Korean Medical books that were easy to comprehend was also because of this philosophy. Conclusions : By making efforts to change and improve reality whether it be medicine or politics, Jo, Heongyeong went beyond treatment of diseases and pursued a world where all people could live healthy lives.

• 셀메드
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• 제14권2호
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• pp.6.1-6.6
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• 2024

The prevalence of respiratory diseases is increasing due to social and environmental factors such as increased environmental pollution and air pollution, and among them, chronic obstructive pulmonary disease (COPD) in particular has a high mortality and morbidity rate worldwide. As a result, medical expenses are rapidly increasing, creating a social and economic burden. In response to this, there is a need to discuss ways to reduce the risk from diseases and manage them appropriately, and the most basic starting point in this process is how these chronic lung disease patients are treated in actual clinical settings and how to improve the quality of treatment. There is a need to look into whether there are effective drugs. Western treatment for chronic obstructive pulmonary disease is basically a disease in which the airway narrows, so bronchodilators are used to widen the bronchi, and corticosteroids and antibiotics are mainly used to relieve the inflammatory response in the lungs. However, since the mainly used Western medicine does not serve as a fundamental therapeutic drug and contains many side effects, there is a need for drugs that improve the quality of life of patients and are more effective in managing symptoms as symptomatic prescriptions. Therefore, Western and Oriental medicine treatments are needed. The purpose is to suggest better treatments through comparative analysis.

• 동의생리병리학회지
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• 제22권3호
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• pp.516-527
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• 2008

Sounds and music have been used in various ways in the East and the West, as it is well known that they influence the human mind and health a lot. Recently, there have been many studies regarding the remedy through sounds and music in the West and they have made good effects in the actual therapy. In the East, people knew that sounds and music would make great effects on human mind long time ago and they placed importance on sounds and music. Although there is a Sound Therapy in Oriental Medicine, it is not studied sufficiently in modern Oriental Medicine. It does not have clear standards for the clinical application and has not been frequently used. Accordingly, Yukjagyeol which has long been used in Korean Medicine and Younggamudo which was made by Kim Il-bu in late Chosun were compared from the perspective of acoustics and demonstrative treatment theory of Korean Medicine. Younggamudo by Kim il-bu allot the five sounds such as 'Eum, Ah, Eo, Ih and Uh' to 'spleen, lung, liver, heart and kidney' respectively. As the five sounds are all vowels and vibrate the vocal band as much as possible, they vibrate and resonant the respective organs to help them to function and promote circulation. In oriental medicine, there is 'Singing and Dancing Treatment'. They say songs and dances nurtures personality, supplement blood stream and comfort the mind. As the five sounds of Younggamudo take the melody while vibrating the vocal band sufficiently, when it passes from Youngto Ga(Songs) we may dance moving our bodies according to the rhythm. Therefore Gongbeop of Younggamudo helps the functionality of human organs and promotes blood circulation. As Yukjagyeol is Sabeop(discharging method), it should be used for those who have surplus Sagi and should not use for Heojeung. As Younggamudo is Bobeop(supplementing method), it is not for Shiljeung but for Heojeung which lacks of Jeonggi. It is considered that healthy people without specific disease can use it as a preventive method of 'Chimijeong' to maintain their physical and mental health. It is considered that we can have useful effects if we apply Yukjagyeol and Younggamudo dialectically with the concept of Bosa. It is considered that concrete application to Sound Gigong can be possible by searching for the methodology for empirical further study and clinical experiments and clinical application in the future.

• 셀메드
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• 제10권2호
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• pp.12.1-12.5
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• 2020

Higher incidences of adverse reaction associated with the prolonged use of synthetic drugs has once again increased the faith of humans in the traditional systems of medicine and motivated them to return back towards the clinical proven remedies for the treatment. It is also true that number of modern medications used in the present scenario, were developed from various plants. In Unani System of medicine, numerous herbal drugs are mentioned for medicinal purpose. Siras (Albizia lebbeck (L.) Benth.) is one of them. It is found all over India. Almost all parts of this plant are used for the treatment of ailments such as migraine, conjunctivitis, diarrhea, jaundice, skin problems, asthma etc. Many chemical constituents have been isolated from Albizia lebbeck such as lebbekannin, echinocystic acid, flavonoids, Linoleic acid, saponins etc. This review highlights the medicinal properties and therapeutic uses of Albizia lebbeck and scientific studies conducted on the drug in human and animal models that will provide the further research direction.

• 대한한의진단학회지
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• 제17권2호
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• pp.156-168
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• 2013

Objectives Although there have been someone who pointed out declining tendency of pure traditional diagnosis, there are no objective survey results on present state of diagnosis among Korean Medicine Doctors (KMDs). So we did a descriptive survey study to show traditional diagnostic modality usage among them. Materials and methods: 73 samples of responded questionnaire in Busan area were collected and descriptively studied. Results (1) U code (in KCD-6) usage showed low level (28.7%). (2) Diagnostic apparatuses for traditional medicine are rarely used. For example, pulse diagnosis machine was reported to be used only by 9.7 % of KMDs. (3) KMDs still prefer the treatment based on pattern identification and symptomatic therapy rather than treatments based on disease identification of modern biomedicine. Conclusion Overall, the portion of pattern identification is still high among KMDs, some kind of diagnostic methods which support pattern identification showed lack of usage.

• 한국한의학연구원논문집
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• 제14권2호
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• pp.67-73
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• 2008

Background: Qigong is one of energy-healing intervention used to prevent and cure ailments and to improve health through regular practice. Although Qigong-neither itself nor its postulated mechanism of action-is within the paradigm of modern Western medical science, effects on the human body could be possible. Objectives: This study aims to know effect of Qigong training in a University student's physical, mental health and self-esteem. Method: There are 120 students who take a Yangsaengkigong(養生氣功) course in D University college of oriental medicine during four weeks beginning in April 10th 2008. I researched 41 of them trained about effect of Qigong training. Result: Qigong training made significant change in self-esteem measurement and SCL-90-R. And there wasn't significant change in KHP and happiness index. Conclusions: The depth study for the each Qigong is needed. Specifically, I think it should be a clinical studies and qualitative research methods for evaluation are needed.

• Korean Journal of Acupuncture
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• 제33권3호
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• pp.139-147
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• 2016

목적 : 침술은 동북아시아 지역의 중심에서 시작하여 2천년 이상의 역사와 함께 아시아뿐만 아니라 근-현대 전 세계의 임상의료 현장에서 크게 번창하고 있다. 이와 함께 침술의 객관화를 위하여 의생명과학 여러 방면에서 검증하는 노력이 진행되어 오고 있다. 그 과정을 통해 각종 동물을 비롯해 사람에서 침술의 다양한 효과와 기전이 점차 밝혀지고 있다. 필자는 침술 치료에서 의사와 환자가 주관적으로 경험하는 것을 설명하고, 그것의 임상적 유의성을 심신의학적 측면에서 이해하고자 하였다. 방법 : 침술과 명상에서 각각 진행되었던 뇌신경과학 분야의 여러 실험 결과들을 비교함으로써 심신 상관성이란 의미를 찾고자 하였다. 그밖에 한의학 임상영역에 시도되는 한의학과 심리학이 접목된 새로운 치료법을 정리하였다. 결과 및 결론: 침술의 치료효과와 관련해 "조기치신(調氣治神)"을 매우 중요한 개념으로 표현하고 있다. 이는 인체에 다양한 기능의 균형을 조절하고, 환자의 의식과 심리상태를 조절한다고 설명한다. 전통의학과 현대의학의 큰 차이는 현대의학은 환자와 질병을 대상화시켜 객관화 하는 노력을 추구하였고, 전통의학은 환자와 의사가 경험하는 대상을 자신과 분리하지 않는 주관적 체험을 추구하고 있다는 것이다. 그리고 전통의학은 주관적 체험을 배제하지 않고 진료에서 활용한다는 것이다. 그래서 전통의학의 역할과 의미를 이해하고자 한다면, 객관적 효과와 수량적 결과뿐만 아니라 환자와 의사의 주관적 체험과 이야기도 중요하게 다뤄져야 한다. 침술의 역할과 의미는 의사와 환자 사이에서 나타나는 행위의 모든 과정을 고려해 설명해야 할 것이다. 아마도 그 과정에서 침술이 찾는 해결의 길은 명상이 찾는 해결의 길과 만날 것이라 믿는다.