Kim, Hong Rae;Lee, Jung Sun;Joo, Yeon Ho;Won, Seunghee;Ryu, Seunghyong;Hong, Kyung Sue;Kwon, Jun Soo;Lee, Seung Yeoun;Oh, Hong Seok;Choi, Joon Ho;Lee, Yu Sang
Korean Journal of Biological Psychiatry
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v.24
no.3
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pp.142-148
/
2017
Objectives The ratio of second to fourth digit length (2D : 4D) could be a potential epigenetic marker of sexual dimorphism reflecting prenatal testosterone exposure. Testosterone is known to affect the development of the brain through an epigenetic mechanism. The purpose of this study was to investigate the effects of exposure to fetal testosterone on the metabolic syndrome based on 2D : 4D of schizophrenia patients and the relationship with the age of onset of schizophrenia. Methods A total of 214 schizophrenia patients participated in this study. The participant's physical and blood tests were performed according to the American National Cholesterol Education Program's Third Amendment of the Metabolic Syndrome Diagnostic Criteria, and the 2D : 4D was measured by the method designed by McFadden. Data were statistically analyzed by t-test, Pearson's correlation analysis and multiple regression model analysis. Results 2D : 4D was significantly higher in female than male in both hands, and there was a statistically significant negative correlation between 2D : 4D and the age of onset of schizophrenia in male. However, 2D : 4D did not show statistically significant correlation with metabolic factors. Conclusions Fetal testosterone suggests the possibility of affecting the age of onset of schizophrenia through the epigenetic mechanism, but there is no clear relationship with metabolic factors.
KSCE Journal of Civil and Environmental Engineering Research
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v.31
no.6D
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pp.839-848
/
2011
TBM (Tunnel Boring Machine) tunnel should be carry out with the adopted machine until the end of excavation because of impossibility of replacement or modification of machine. Observation of the face of the tunnel is difficult, especially in EPB(Earth Pressure Balance) shield TBM, predict changes in the ground condition with analyzing data, collected during the excavation, and it should be reflected in construction. Until recently, subjects of studies on TBM are mainly the determination of machine and the development of advance rate prediction model, according to the characteristics of ground which is the target of excavation. However, study focused on the estimation of ground conditions and the improvement in operational methods using excavation data of TBM equipment, the principal of the excavation, has been done not so much. This study examine the variances in advance rate depending on changes in operating conditions and evaluate the optimal operating conditions of adopt machine, using working data obtained from EPB shield TBM project. The result of this study is suggested as follows. First, cutter head RPM and total thrust force are biggest influences on advance rate, Second, it is recommended for proper advance rate that total thrust force is controlled while optimum cutter head RPM is kept, Third, according to the increasing trend of total thrust force, the changes in ground conditions can be predicted, the appropriate operating conditions can be determined.
Journal of Korean Society of Coastal and Ocean Engineers
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v.25
no.2
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pp.112-121
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2013
The calibration of resistance factor in reliability theory for limit state design of gravel compaction piles (GCP) requires a reliable estimate of ultimate bearing capacity. The static load test is commonly used in geotechnical engineering practice to predict the ultimate bearing capacity. Many graphical methods are specified in the design standard to define the ultimate bearing capacity based on the load-settlement curve. However, it has some disadvantages to ensure reliability to obtain an uniform ultimate load depend on engineering judgement. In this study, a well-fitting nonlinear regression model is proposed to estimate the ultimate bearing capacity, for which a nonlinear regression analysis is applied to estimate the ultimate bearing capacity of GCP and the results are compared with those calculated using previous graphical method. Affect the resistance factor of the estimate method were analyzed. To provide a database in the development of limit state design, the load test conditions for predicting the ultimate bearing capacity from static load test are examined.
Efficient numerical method is developed for the prediction of aerodynamic noise generation and propagation in low Mach number flows such as aeolian tone noise. The proposed numerical method is based on acoustic/viscous splitting techniques of which acoustic solvers use simplified linearised Euler equations, full linearised Euler equations and nonlinear perturbation equations as acoustic governing equations. All of acoustic equations are forced with immersed surface dipole model which is developed for the efficient computation of aerodynamic noise generation and propagation in low Mach number flows in which dipole source, originating from unsteady pressure fluctuation on a solid surface, is known to be more efficient than quadrupole sources. Multi-scale overset grid technique is also utilized to resolve the complex geometries. Initially, aeolian tone from single cylinder is considered to examine the effects that the immersed surface dipole models combined with the different acoustic governing equations have on the overall accuracy of the method. Then, the current numerical method is applied to the simulation of the aeolian tones from twin cylinders aligned perpendicularly to the mean flow and separated 3 diameters between their centers. In this configuration, symmetric vortices are shed from twin cylinders, which leads to the anti-phase of the lift dipoles and the in-phase of the drag dipoles. Due to these phase differences, the directivity of the fluctuating pressure from the lift dipoles shows the comparable magnitude with that from the drag dipoles at 10 diameters apart from the origin. However, the directivity at 100 diameters shows that the lift-dipole originated noise has larger magnitude than, but still comparable to, that of the drag-dipole one. Comparison of the numerical results with and without mean flow effects on the acoustic wave emphasizes the effects of the sheared background flows around the cylinders on the propagating acoustic waves, which is not generally considered by the classic acoustic analogy methods. Through the comparison of the results using the immersed surface dipole models with those using point sources, it is demonstrated that the current methods can allow for the complex interactions between the acoustic wave and the solid wall and the effects of the mean flow on the acoustic waves.
Up until recently, Korea has ranked the first place in UN e-Government Survey for three consecutive years. In keeping with such accomplishment, the size of budget execution has been consistently growing in accordance with Korea's Government 3.0 policy and vision, leading to increase in big-sized informatization projects in the business. Especially in mission critical public sector's infrastructure where it affects many people, growing demand for establishing high-quality information system with new technologies being brought to attention in order to meet the complex needs of citizens. National defense information system, being one of representative domains examples in the concerned area, established high military competency by applying breakthrough technology. Network-oriented national defense knowledge informatization was set as the vision in order to implement core roles in making efficient national defense management; and effort has been made to materialize the vision by making advancement in national defense's information system and its informatization implementation system. This research studies new quality index relevant to test and evaluation (T&E)of informatization business in national defense which is the representative example of mission critical public sector's infrastructure. We studied international standards and guidelines, analyzed actual T&E cases, and applied them to the inspection items that are currently in use, complying with the e-government law (Act No. 12346, Official Announcement Date 2014. 1.28., Enforcement Date 2014. 7.29.) As a result of productivity analysis, based on hypothesis in which suggested model was applied to T&E of the national defense informatization business, we confirmed the possibility of enhancement in the T&E productivity by assessing reliability, expertise, and safety as evaluation factors.
The development of treatment technologies for recycling waste woods generated from tree pruning is required in Gangwon province forest. In this study, according to adsorption experiments using three types (Larix kaemoferi, Juniperus chinensis, Pinus densiflora) of waste woods, Juniperus chinensis as a biosorbent showing an excellent removal ability was selected for the removal of methylene blue in an aqueous phase. When 0.4 g/100 mL of Juniperus chinensis was used to improve the removal efficiency of methylene blue for 4 h, each 100, 200 and 300 mg/L of methylene blue dissolved in the aqueous phase were removed to 98, 93, and 81%, respectively. The adsorption equilibrium data obtained by changing adsorbent concentrations was found to be more consistent with the Langmuir than the Freundlich equation. In addition, based on dynamic experiments by changing the methylene blue concentration, the biosorption kinetics equation was more suitable for a pseudo-second order model. In order to enhance the removal capability of highly concentrated methylene blue, 300 and 400 mg/L of methylene blue were operated for 4 h under 210 rpm of agitation velocity and removal efficiencies were 92 and 76%, respectively. Consequently, these experimental results can be effectively utilized as a new biosorption technology for economically treating methylene blue dissolved in an aqueous phase.
Recently, the area of ubiquitous has gained a great attention both in academics and in business organizations as we are entering an ubiquitous society where people can interact at "anytime" and "anywhere". To preoccupy the leading status for the next generation of IT technology, many countries such as Korea, Japan, and US are concerned the ubiquitous. In this tendency, companies want to identify what factors make people use ubiquitous in order to develop the effective ubiquitous service and to supply the higher quality service. However, prior researches on ubiquitous are focused on technical area such as higher data delivery, efficient compression of images, so they do not have given companies beneficial materials for making fascinating ubiquitous services. To offer the service materials for development, from the viewpoint of the customer, important factors to use ubiquitous services are investigated in this study. Moreover, the study was progressed up to the new area of investigation how much these factors influenced ubiquitous service actual usage. To achieve these goals, Ubiquitous service adopting reflected in ubiquitous service characteristics was suggested in this study. The results of this study are as follows. First, contextual offer, ubiquity, invisibility are positively related to perceived value. Second, perceived value is positively related to usage intention but perceived risk is negatively related to usage intention. Third, usage intention is positively related to usage frequency. Based on these results, managerial implications for ubiquitous service vitalization are discussed. Lastly, the limitation of this research and further research issues are suggested.
What are the critical factors in deciding future career to the gifted and talented students? The present study started with this question, and was to develop a career decision-making scale for scientifically gifted undergraduates. For this, literatures related to the scientifically gifted/talent and scientists' career decision-making were reviewed and examined in depth. Based on the review of the related literature, the developed scale of career decision-making was comprised of 26 items in 6 factors, such as individual aptitude & self-realization, economic aspect, work & leisure, familial influence, parents/teachers' recommendation, and experience of science activity during the school days. For the preliminary exploratory factor analysis, 153 undergraduate students who were majoring in natural sciences and engineer participated in the study. For the confirmatory factor analysis, 264 undergraduates who were awarded the presidential scholarships and 93 undergraduates who completed a university-affiliated gifted education center participated. The results of the study are as follows. The fit of measurement model was found to be $x^{2}$=645.157 (df=279, p=.00), TLI=.924, CFI= .935, RMSEA=.061, indicating most of fit indexes were acceptable. Cronbach's ${\alpha}$ in each sub-factor was quite high, .82 for individual aptitude & self-realization, .94 for economic aspect, .84 for work and leisure, .88 for familial influence, .79 for patents/ teachers' recommendation, and .79 for experience of science activity during the school days. The results of the study were discussed whether the developed scale could be used as a valid and reliable tool for measuring career decision-making factors of the scientifically gifted undergraduates in our country.
Cho, Young Sun;Lim, No Yeol;Joung, Woo Su;Jung, Sung Heuk;Choi, Seok Keun
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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v.32
no.5
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pp.551-560
/
2014
Compare to other industrial sites, the civil construction work not only takes longer time but also has made of complicated processes, such as the integrated management, process control, and quality control until the completion. However, it is hard to take control the construction sites, since numerous issues are always emerged. The study purposes on providing the dataset to synthetically manage and monitor the civil construction site, main design, drawings, process, construction cost, and others at real-time by using the low altitude close-range aerial images, based on UAV, and the GPS surveying method for treating the three-dimensional spatial information quickly and accurately. As a result, we could provide the latest information for the quick decision-making following from planning to completion of the construction, and objective site evaluation by the high-resolution three-dimensional spatial information and drawings. Also, the present map, longitudinal map, and cross sectional view are developed to provide various datasets rapidly, such as earthwork volume table, specifications, and transition of ground level.
The purpose of this study was to develop a simple, valid, and reliable instrument for measuring forward flexion of trunk-hip joint. The subject included 44 females for sports major of volunteers at D. Women's University. In establishing the validity, objectivity the reliability of the new flexibility test(NF-test) for trunk-hip joint, Takei- flexometer(modified Leighton flexometer) was administered as the reference instrument, and test-retest method was utilized with the best scores. Intraclass correlation coefficient was obtained to use two way-mixed effect model and this value was average measure. The Pearson product correlation coefficient of L in this study were; the new flexibility test and Takei-flexometer as the reference tool correlated r = .962 in the first test, r = .960 in the second test. The intraclass correlation coefficient of the new flexibility test between in the initial test and in the retest were R = .994 for L, R =.993 for Y, and the intraclass correlation coefficient of the new flexibility test between L and Y were R =.985 in the initial test, and R =.986 in the retest. Based on the above findings, the following conclusions are presented. It was found the new flexibility test (NF test) was a valid, reliable, objective tool for measuring forward flexion of trunk-hip joint, and possible to be recommended as he test for measuring trunk-hip flexibility in the field.
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