• Title/Summary/Keyword: Model fit

Search Result 2,879, Processing Time 0.029 seconds

Association between a Genetic Variant of CACNA1C and the Risk of Schizophrenia and Bipolar I Disorder Across Diagnostic Boundaries (조현병과 제1형 양극성장애의 진단 경계를 넘어선 공통적 후보유전자로서의 CACNA1C에 대한 단일염기다형성 연합 연구)

  • Lee, Bora;Baek, Ji Hyun;Cho, Eun Young;Yang, So-Yung;Choi, Yoo Jin;Lee, Yu-Sang;Ha, Kyooseob;Hong, Kyung Sue
    • Korean Journal of Schizophrenia Research
    • /
    • v.21 no.2
    • /
    • pp.43-50
    • /
    • 2018
  • Objectives : Genome-wide association studies (GWASs) and meta-analyses indicate that single-nucleotide polymorphisms (SNPs) in the a-1C subunit of the L-type voltage-dependent calcium channel (CACNA1C) gene increase the risk for schizophrenia and bipolar disorders (BDs). We investigated the association between the genetic variants on CACNA1C and schizophrenia and/or BDs in the Korean population. Methods : A total of 582 patients with schizophrenia, 336 patients with BDs consisting of 179 bipolar I disorder (BD-I) and 157 bipolar II disorder (BD-II), and 502 healthy controls were recruited. Based on previous results from other populations, three SNPs (rs10848635, rs1006737, and rs4765905) were selected and genotype-wise association was evaluated using logistic regression analysis under additive, dominant and recessive genetic models. Results : rs10848635 showed a significant association with schizophrenia (p=0.010), the combined schizophrenia and BD group (p=0.018), and the combined schizophrenia and BD-I group (p=0.011). The best fit model was dominant model for all of these phenotypes. The association remained significant after correction for multiple testing in schizophrenia and the combined schizophrenia and BD-I group. Conclusion : We identified a possible role of CACNA1C in the common susceptibility of schizophrenia and BD-I. However no association trend was observed for BD-II. Further efforts are needed to identify a specific phenotype associated with this gene crossing the current diagnostic categories.

Why Genuine Luxury Brands Are Consumed? Counterfeits? Examining Consumer Identification

  • Suh, Hyunsuk
    • Asia Marketing Journal
    • /
    • v.14 no.3
    • /
    • pp.69-102
    • /
    • 2012
  • Owing to increased number of luxury brand users, both genuine and counterfeit luxury product consumption continues to increase every year. Luxury brand is defined as use or display of a particular branded products which brings the ownership prestige apart from its functional utility(Grossmand and Shapiro 1988). Some luxury brands have imitations sold in marketplace due to their popularity. These imitations or counterfeits have been jumping on the bandwagon of the upturn in sales of their originals. The purpose of our study is to understand consumer's underlying motives to consume luxury brands, genuine and or counterfeits. To do this, we propose functional theories of attitudes, decision-making styles, and life attitudes to form the determining causes for different consumption choices of luxury brands: genuine brands, counterfeit brands, both genuine and counterfeit brands, and no consumption on luxury brands types. In proposed causal pathways, we examine moderated effects of socio-psychological factors to further investigate if consumer profiles would exert influences in causal relationships. From the existing theories of functional attitudes: value-expressive and social-adjustive attitudes, we developed and introduced a new measure of rationality-consumptive attitude. From the existing eight decision-making characteristics of consumer styles inventory(CSI), three measures of high-quality, hedonic-shopping, and price-shopping styles were primarily applied in the study along with newly introduced measure of 'high-price' being added, which makes four total. Seven life attitude measures of life purpose, life control, will to meaning, goal seeking, future mean to fulfill, life satisfaction, and religiosity were applied. Finally, such socio-psychological measures as age, gender, marital status, income, and age-gap between couples were assumed to function as moderators. With 430 valid study samples, ages from 20s to 50s, with more females(316) than males(114), with average personal possessions of 5 genuine and 9 counterfeit luxury brands, we conducted questionnaire survey. Results indicated that social-adjustive function is totally disappeared in the relationship due to current social trend of widespread consumptions on both genuine and counterfeit brands which in turn, make consumers feel less special on wearing or carrying them unlike in the past. Self-expressive function and rationality-consumptive functions act as strong catalysts for genuine brand consumption and counterfeit brand consumption, respectively. On consumers' decision-making styles, high-price sublation is the most powerful indicator anticipating counterfeit consumption, even more powerful than personal incomes. In life attitude, the overall model fit was not validated, and only life control and life satisfaction are proven to be significant on both genuine and counterfeit product consumptions. Employment of socio-psychological factors in the model improved understanding of users further. Young consumers tend to go for genuine products over counterfeits. Consumers in different income groups; low, medium and high, all significantly consume genuine products for reasons of different decision-making styles. The results indicated that consumers whose personal disposition is predisposed to consume products in the form of reflection of his or her personality, go only for genuine brands for quality reason, while consumers who rationally consume products for its function or usability, go only for counterfeits for high-price sublation reason. Meanwhile, both product users support for high-price orientation who are not well off.

  • PDF

Effects of Retirement Stress, Character Strengths, and Marital Dissatisfaction on Post-retirement Depression (은퇴 남성의 은퇴스트레스, 성격 강점, 결혼불만족이 은퇴 후 우울에 미치는 영향)

  • Sun Young Kim;Hyae Young Yoon
    • Korean Journal of Culture and Social Issue
    • /
    • v.19 no.4
    • /
    • pp.553-576
    • /
    • 2013
  • The purpose of this study was to investigate the impact of retirement stress, character strengths and marital dissatisfaction on depression. Additionally this study examined direct effects and indirect effects of character strengths and marital dissatisfaction. The participant group was composed of 197 retired men living in Daegu and Gyongsangbuk-do. The Retirement Stress Scale (RSS), Character Strengths Test (CST), Korean Marital Satisfaction Inventory (K-MSI), and Center for Epistemology Studies Depression scale (CES-D) were administered to participants. Structural Equation Modeling (SEM) with AMOS was used for the purpose of analysis. The results of the study were as follows. First, an increase in retirement stress was associated with higher levels of depression. Second, hierarchical regression analysis indicated that higher levels of optimism significantly predicted higher depression. Also hierarchical regression analysis indicated that lower levels of appreciation of beauty and excellence without optimism significantly predicted higher depression. Furthermore, increases in marital dissatisfaction were associated with higher levels of depression. Third, the constructed model including both direct effects and indirect effects appeared to fit better than alternative model in explaining relationships between retirement stress and depression. In other words, character strengths and marital dissatisfaction appeared to affect the depression levels of retired men directly and indirectly. To sum up, this study demonstrated that the factors which had an effect on depression in retired men, character strengths and harmonious marital relationships appeared to act as a buffer against depression in retired men. The current results might serve as basic data for psychological well-being programs for retired men. Finally, the limitations and implications of the current study were discussed.

  • PDF

Effect of Dam Operation on the Spatial Variability of Downstream Flow (댐운영에 따른 하류하천 유량의 공간적 변동성 평가)

  • Jeong Eun Lee;Jeongwoo Lee;Chul-gyum Kim;Il-moon Chung
    • The Journal of Engineering Geology
    • /
    • v.33 no.4
    • /
    • pp.627-638
    • /
    • 2023
  • This study aimed to evaluate the spatial variability of downstream river flow resulting from the operation of the Gimcheon Buhang Dam in the Gamcheon watershed. The dam's effects on flood reduction during the flood season and on increasing streamflow during the dry season-two main functions of multipurpose dams-were quantitatively analyzed. Streamflow data from 2013 to 2021 for the study waterhsed were simulated on a daily basis using SWAT-K (Soil and Water Assessment Tool - Korea) model. Comparison of the simulated and observed values found goodness of fit values of 0.75 or higher for both the coefficient of determination and the Nash-Sutcliffe model efficiency coefficient. The spatial analysis of the dam's effect on flood reduction focused on the annual maximum flood: rates of flood reduction at the four stations ranged from 8.5% to 25.0%. The evaluation of streamflow increase during times of low flow focused on flow duration curves: in particular, compared to the case without an upstream dam, the average low flow at the four sites increased from 33% to 198%.

A Validation Study of the Korean Version of the Workplace Intergenerational Climate Scale(K-WICS) (한국판 세대친화적 조직문화척도(K-WICS) 타당화 연구)

  • Seoyeong Jeong;Hee Woong Park;Young Woo Sohn
    • Korean Journal of Culture and Social Issue
    • /
    • v.29 no.4
    • /
    • pp.429-453
    • /
    • 2023
  • Due to recent demographic changes, employees from diverse generations now work together in organizations. Thus, there is a need for research on intergenerational cooperation. However, the lack of valid and reliable measures to capture intergenerational climate in the workplace is an obstacle to research. Therefore, we translated the Workplace Intergenerational Climate Scale(WICS) into Korean and validated it with a sample of 1,052 Korean full-time employees. Firstly, we conducted an exploratory factor analysis by using sample 1(N = 460) and revealed a five-factor solution. Secondly, the confirmatory factor analysis(sample 2; N = 592) showed a good model fit of the correlated five-factor model. Thirdly, the scale's discriminant and convergent validity was supported by negative correlations with four types of existing ageism scales and by positive correlations with trust, organizational commitment, work engagement, psychological safety, intention to remain, job satisfaction, and communication satisfaction. Moreover, it further demonstrated significant incremental validity in predicting positive outcome variables even when controlling for pre-existing agism scales. Lastly, we confirmed strict measurement invariance of the scale between the age groups(below 40 versus above 40). The findings support the reliability and validity of the Korean version of WICS among Korean employees. The scale will be broadly applied to measure intergenerational climate of organizations and provide practical implications for HR management.

Reactive and Proactive Aggression, the Validation of the Reactive-Proactive Questionnaire (RPQ): Focusing on ESEM and Rasch (반응적 공격성과 주도적 공격성, Reactive-Proactive Questionnaire(RPQ) 타당화 연구: ESEM과 Rasch를 중심으로)

  • Seonyoung Park;Jonghan Sea
    • Korean Journal of Culture and Social Issue
    • /
    • v.30 no.2
    • /
    • pp.159-192
    • /
    • 2024
  • The purpose of this study is to validate the Reactive-Proactive Aggression Questionnaire (RPQ), a tool for measuring reactive-proactive aggression, in the context of South Korea. A thorough translation was conducted in collaboration with the original author. An exploratory factor analysis (EFA), exploratory structural equation modeling (ESEM), rating scale model (Rasch), differential item functioning (DIF), and convergent validity were performed on a sample of 510 South Korean individuals. The results revealed a two-factor structure of reactive and proactive aggression after removing one item showing dual loading. Rating scale analysis based on the Rasch model indicated the appropriateness of the 3-point Likert scale, with all items meeting fit criteria. Although the separation index and separation reliability of proactive aggression was marginally lower, the overall discrimination between participants and items was satisfactory. Examination of participant-item distribution indicated a suitable alignment between reactive aggression and participant ability levels, whereas proactive aggression exhibited slightly elevated item difficulty. Furthermore, three items were found to function differently based on gender. A moderate but statistically significant positive correlation was found between the Barratt Impulsiveness Scale-11-R (Korean version) and RPQ from the results of the convergent validity evaluation. Overall, this study employed rigorous statistical methods to validate the suitability of the RPQ for use in Korea, taking cultural nuances into account, and introduced the concepts of reactive and proactive aggression to the Korean general population.

Comparison of Monoexponential, Biexponential, Stretched-Exponential, and Kurtosis Models of Diffusion-Weighted Imaging in Differentiation of Renal Solid Masses

  • Jianjian Zhang;Shiteng Suo;Guiqin Liu;Shan Zhang;Zizhou Zhao;Jianrong Xu;Guangyu Wu
    • Korean Journal of Radiology
    • /
    • v.20 no.5
    • /
    • pp.791-800
    • /
    • 2019
  • Objective: To compare various models of diffusion-weighted imaging including monoexponential apparent diffusion coefficient (ADC), biexponential (fast diffusion coefficient [Df], slow diffusion coefficient [Ds], and fraction of fast diffusion), stretched-exponential (distributed diffusion coefficient and anomalous exponent term [α]), and kurtosis (mean diffusivity and mean kurtosis [MK]) models in the differentiation of renal solid masses. Materials and Methods: A total of 81 patients (56 men and 25 women; mean age, 57 years; age range, 30-69 years) with 18 benign and 63 malignant lesions were imaged using 3T diffusion-weighted MRI. Diffusion model selection was investigated in each lesion using the Akaike information criteria. Mann-Whitney U test and receiver operating characteristic (ROC) analysis were used for statistical evaluations. Results: Goodness-of-fit analysis showed that the stretched-exponential model had the highest voxel percentages in benign and malignant lesions (90.7% and 51.4%, respectively). ADC, Ds, and MK showed significant differences between benign and malignant lesions (p < 0.05) and between low- and high-grade clear cell renal cell carcinoma (ccRCC) (p < 0.05). α was significantly lower in the benign group than in the malignant group (p < 0.05). All diffusion measures showed significant differences between ccRCC and non-ccRCC (p < 0.05) except Df and α (p = 0.143 and 0.112, respectively). α showed the highest diagnostic accuracy in differentiating benign and malignant lesions with an area under the ROC curve of 0.923, but none of the parameters from these advanced models revealed significantly better performance over ADC in discriminating subtypes or grades of renal cell carcinoma (RCC) (p > 0.05). Conclusion: Compared with conventional diffusion parameters, α may provide additional information for differentiating benign and malignant renal masses, while ADC remains the most valuable parameter for differentiation of RCC subtypes and for ccRCC grading.

Simulation analysis and evaluation of decontamination effect of different abrasive jet process parameters on radioactively contaminated metal

  • Lin Zhong;Jian Deng;Zhe-wen Zuo;Can-yu Huang;Bo Chen;Lin Lei;Ze-yong Lei;Jie-heng Lei;Mu Zhao;Yun-fei Hua
    • Nuclear Engineering and Technology
    • /
    • v.55 no.11
    • /
    • pp.3940-3955
    • /
    • 2023
  • A new method of numerical simulating prediction and decontamination effect evaluation for abrasive jet decontamination to radioactively contaminated metal is proposed. Based on the Computational Fluid Dynamics and Discrete Element Model (CFD-DEM) coupled simulation model, the motion patterns and distribution of abrasives can be predicted, and the decontamination effect can be evaluated by image processing and recognition technology. The impact of three key parameters (impact distance, inlet pressure, abrasive mass flow rate) on the decontamination effect is revealed. Moreover, here are experiments of reliability verification to decontamination effect and numerical simulation methods that has been conducted. The results show that: 60Co and other homogeneous solid solution radioactive pollutants can be removed by abrasive jet, and the average removal rate of Co exceeds 80%. It is reliable for the proposed numerical simulation and evaluation method because of the well goodness of fit between predicted value and actual values: The predicted values and actual values of the abrasive distribution diameter are Ф57 and Ф55; the total coverage rate is 26.42% and 23.50%; the average impact velocity is 81.73 m/s and 78.00 m/s. Further analysis shows that the impact distance has a significant impact on the distribution of abrasive particles on the target surface, the coverage rate of the core area increases at first, and then decreases with the increase of the impact distance of the nozzle, which reach a maximum of 14.44% at 300 mm. It is recommended to set the impact distance around 300 mm, because at this time the core area coverage of the abrasive is the largest and the impact velocity is stable at the highest speed of 81.94 m/s. The impact of the nozzle inlet pressure on the decontamination effect mainly affects the impact kinetic energy of the abrasive and has little impact on the distribution. The greater the inlet pressure, the greater the impact kinetic energy, and the stronger the decontamination ability of the abrasive. But in return, the energy consumption is higher, too. For the decontamination of radioactively contaminated metals, it is recommended to set the inlet pressure of the nozzle at around 0.6 MPa. Because most of the Co elements can be removed under this pressure. Increasing the mass and flow of abrasives appropriately can enhance the decontamination effectiveness. The total mass of abrasives per unit decontamination area is suggested to be 50 g because the core area coverage rate of the abrasive is relatively large under this condition; and the nozzle wear extent is acceptable.

Rice Yield Estimation Using Sentinel-2 Satellite Imagery, Rainfall and Soil Data (Sentinel-2 위성영상과 강우 및 토양자료를 활용한 벼 수량 추정)

  • KIM, Kyoung-Seop;CHOUNG, Yun-Jae;JUN, Byong-Woon
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.25 no.1
    • /
    • pp.133-149
    • /
    • 2022
  • Existing domestic studies on estimating rice yield were mainly implemented at the level of cities and counties in the entire nation using MODIS satellite images with low spatial resolution. Unlike previous studies, this study tried to estimate rice yield at the level of eup-myon-dong in Gimje-si, Jeollabuk-do using Sentinel-2 satellite images with medium spatial resolution, rainfall and soil data, and then to evaluate its accuracy. Five vegetation indices such as NDVI, LAI, EVI2, MCARI1 and MCARI2 derived from Sentinel-2 images of August 1, 2018 for Gimje-si, Jeollabuk-do, rainfall and paddy soil-type data were aggregated by the level of eup-myon-dong and then rice yield was estimated with gamma generalized linear model, an expanded variant of multi-variate regression analysis to solve the non-normality problem of dependent variable. In the rice yield model finally developed, EVI2, rainfall days in September, and saline soils ratio were used as significant independent variables. The coefficient of determination representing the model fit was 0.68 and the RMSE for showing the model accuracy was 62.29kg/10a. This model estimated the total rice production in Gimje-si in 2018 to be 96,914.6M/T, which was very close to 94,470.3M/T the actual amount specified in the Statistical Yearbook with an error of 0.46%. Also, the rice production per unit area of Gimje-si was amounted to 552kg/10a, which was almost consistent with 550kg/10a of the statistical data. This result is similar to that of the previous studies and it demonstrated that the rice yield can be estimated using Sentinel-2 satellite images at the level of cities and counties or smaller districts in Korea.

A Study on the Clustering Method of Row and Multiplex Housing in Seoul Using K-Means Clustering Algorithm and Hedonic Model (K-Means Clustering 알고리즘과 헤도닉 모형을 활용한 서울시 연립·다세대 군집분류 방법에 관한 연구)

  • Kwon, Soonjae;Kim, Seonghyeon;Tak, Onsik;Jeong, Hyeonhee
    • Journal of Intelligence and Information Systems
    • /
    • v.23 no.3
    • /
    • pp.95-118
    • /
    • 2017
  • Recent centrally the downtown area, the transaction between the row housing and multiplex housing is activated and platform services such as Zigbang and Dabang are growing. The row housing and multiplex housing is a blind spot for real estate information. Because there is a social problem, due to the change in market size and information asymmetry due to changes in demand. Also, the 5 or 25 districts used by the Seoul Metropolitan Government or the Korean Appraisal Board(hereafter, KAB) were established within the administrative boundaries and used in existing real estate studies. This is not a district classification for real estate researches because it is zoned urban planning. Based on the existing study, this study found that the city needs to reset the Seoul Metropolitan Government's spatial structure in estimating future housing prices. So, This study attempted to classify the area without spatial heterogeneity by the reflected the property price characteristics of row housing and Multiplex housing. In other words, There has been a problem that an inefficient side has arisen due to the simple division by the existing administrative district. Therefore, this study aims to cluster Seoul as a new area for more efficient real estate analysis. This study was applied to the hedonic model based on the real transactions price data of row housing and multiplex housing. And the K-Means Clustering algorithm was used to cluster the spatial structure of Seoul. In this study, data onto real transactions price of the Seoul Row housing and Multiplex Housing from January 2014 to December 2016, and the official land value of 2016 was used and it provided by Ministry of Land, Infrastructure and Transport(hereafter, MOLIT). Data preprocessing was followed by the following processing procedures: Removal of underground transaction, Price standardization per area, Removal of Real transaction case(above 5 and below -5). In this study, we analyzed data from 132,707 cases to 126,759 data through data preprocessing. The data analysis tool used the R program. After data preprocessing, data model was constructed. Priority, the K-means Clustering was performed. In addition, a regression analysis was conducted using Hedonic model and it was conducted a cosine similarity analysis. Based on the constructed data model, we clustered on the basis of the longitude and latitude of Seoul and conducted comparative analysis of existing area. The results of this study indicated that the goodness of fit of the model was above 75 % and the variables used for the Hedonic model were significant. In other words, 5 or 25 districts that is the area of the existing administrative area are divided into 16 districts. So, this study derived a clustering method of row housing and multiplex housing in Seoul using K-Means Clustering algorithm and hedonic model by the reflected the property price characteristics. Moreover, they presented academic and practical implications and presented the limitations of this study and the direction of future research. Academic implication has clustered by reflecting the property price characteristics in order to improve the problems of the areas used in the Seoul Metropolitan Government, KAB, and Existing Real Estate Research. Another academic implications are that apartments were the main study of existing real estate research, and has proposed a method of classifying area in Seoul using public information(i.e., real-data of MOLIT) of government 3.0. Practical implication is that it can be used as a basic data for real estate related research on row housing and multiplex housing. Another practical implications are that is expected the activation of row housing and multiplex housing research and, that is expected to increase the accuracy of the model of the actual transaction. The future research direction of this study involves conducting various analyses to overcome the limitations of the threshold and indicates the need for deeper research.