• Journal of the Earthquake Engineering Society of Korea
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• v.13 no.3
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• pp.11-19
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• 2009

Recently, concerns relating to the maintenance of large structures have been increased. In addition, the number of large structures that need to be evaluated for their structural safety due to natural disasters and structural deterioration has been rapidly increasing. It is common for the structural characteristics of an older large structure to differ from the characteristics in the initial design stage, and changes in dynamic characteristics may result from a reduction in stiffness due to cracks on the materials. The process of deterioration of such structures enables the detection of damaged locations, as well as a quantitative evaluation. One of the typical measuring instruments used for the monitoring of bridges and buildings is the dynamic measurement system. Conventional dynamic measurement systems require considerable cabling to facilitate a direct connection between sensor and DAQ logger. For this reason, a method of measuring structural responses from a remote distance without the mounted sensors is needed. In terms of non-contact methods that are applicable to dynamic response measurement, the methods using the doppler effect of a laser or a GPS are commonly used. However, such methods could not be generally applied to bridge structures because of their costs and inaccuracies. Alternatively, a method using a visual image can be economical as well as feasible for measuring vibration signals of inaccessible bridge structures and extracting their dynamic characteristics. Many studies have been conducted using camera visual signals instead of conventional mounted sensors. However, these studies have been focused on measuring displacement response by an image processing technique after recording a position of the target mounted on the structure, in which the number of measurement targets may be limited. Therefore, in this study, a model experiment was carried out to verify the measurement algorithm for measuring multi-point displacement responses by using a DIC (Digital Image Correlation) technique.

• JSTS:Journal of Semiconductor Technology and Science
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• v.5 no.3
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• pp.149-158
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• 2005

This paper describes design, fabrication, and application of the silicon based temperature controllable micro reactor. In order to achieve fast temperature variation and low energy consumption, reaction chamber of the micro reactor was thermally isolated by etching the highly conductive silicon around the reaction chamber. Compared with the model not having thermally isolated structure, the thermally isolated micro reactor showed enhanced thermal performances such as fast temperature variation and low energy consumption. The performance enhancements of the micro reactor due to etched holes were verified by thermal experiment and numerical analysis. Regarding to 42 percents reduction of the thermal mass achieved by the etched holes, approximately 4 times faster thermal variation and 5 times smaller energy consumption were acquired. The total size of the fabricated micro reactor was $37{\times}30{\times}1mm^{3}$. Microchannel and reaction chamber were formed on the silicon substrate. The openings of channel and chamber were covered by the glass substrate. The Pt electrodes for heater and sensor are fabricated on the backside of silicon substrate below the reaction chamber. The dimension of channel cross section was $200{\times}100{\mu}m^{2}$. The volume of reaction chamber was $4{\mu}l$. The temperature of the micro reactor was controlled and measured simultaneously with NI DAQ PCI-MIO-16E-l board and LabVIEW program. Finally, the fabricated micro reactor and the temperature control system were applied to the thermal denaturation and the trypsin digestion of protein. BSA(bovine serum albumin) was chosen for the test sample. It was successfully shown that BSA was successfully denatured at $75^{\circ}C$ for 1 min and digested by trypsin at $37^{\circ}C$ for 10 min.

• Journal of Korea Water Resources Association
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• v.51 no.5
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• pp.425-438
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• 2018

Existing studies that analyze the causes and effects of water circulation use mostly rainfall - runoff models, which requires much effort in model development, calibration and verification. In this study, hydrological sensitivity analysis which can separate quantitatively the impacts by natural factors and anthropogenic factor was applied to the Hwacheon dam upper basin from 1967 to 2017. As a result of using various variable change point detection methods, 1999 was detected as a statistically significant change point. Especially, based on the hydrological sensitivity analysis using 5 Budyko based functions, it was estimated that the average inflow reduction amount by Imnam dam construction was $1.890\;billion\;m^3/year$. This results in this study was slightly larger than the those by existing researchers due to increase of rainfall and decrease of Hwacheon dam inflow. In future, it was suggested that effective water management measures were needed to resolve theses problems. Especially, it can be suggested that the monthly or seasonal analysis should be performed and also the prediction of discharge for future climate change should be considered to establish resonable measures.

• Journal of the Korea Concrete Institute
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• v.17 no.6 s.90
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• pp.955-962
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• 2005

Still no accurate theory exists for predicting ultimate shear strength of deep reinforced concrete beams because of the structural and material non-linearity after cracking. Currently, the load capacity assesment is performed for the upper structure of the bridges and containing non-reliability in the applications and results. The purpose in this study is to evaluate analytically the complex shear behaviors and normal strength for the reinforced concrete deep beams and to offer the accuracy load capacity assesment method based on the reliability theories. This paper presents a method for the load capacity assesment of reinforcement concrete deep beams using nonlinear finite element analysis. A computer program named RCAHEST (Reinforced Concrete Analysis in Higher Evaluation System Technology), for the analysis of reinforced concrete structures was used. Material non-linearity is taken Into account by comprising tensile, compressive and shear models of cracked concrete and a model of reinforcing steel. From the results, determine the reliability index for the failure base on the Euro Code. Then, calculate additional reduction coefficient to satisfy the goals from the reliability analysis. The proposed numerical method for the load capacity assesment of reinforced concrete deep beams is verified by comparison with the others methods.

• Journal of Environmental Policy
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• v.8 no.4
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• pp.25-36
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• 2009

The Total Pollutant Load Management System(TPLMS) in the Han River basin is being changed from a voluntary to a mandatory system. Accordingly, this study suggests directions and priorities for research that can support implementation of TPLMS through an objective approach that deploys gap analysis and analytic hierarchy processes (AHP). Gap analysis indicated that TPLMS in Korea is still focused on compliance with regulations, and that implementation of TPLMS is still in its early stage. Improvements are thus needed in flexibility and effectiveness, including introduction of emissions rights trading, and upgrading to a renewable emissions permit system. The AHP study indicated that R&D will need to proceed in parallel in multiple areas to improve systems and resolve scientific uncertainties. Balanced R&D will be needed in both the institutional and technical groups. Subgroup analysis indicated that developing a reasonable process to establish water quality management targets is of the highest priority in the institutional group. In the technical group, higher priority will need to be given to improving model reliability and developing innovative pollution load reduction technologies.

• The Korea Journal of Herbology
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• v.32 no.1
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• pp.25-31
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• 2017

Objectives : Mori Radicis Cortex (MRC), the root epidermis of Morus alba L., has been traditionally used to treat lung-related diseases in Korean Medicine. The common of MRC is Mulberry bark Morus bark, and it's pharmaceutical properties and taste are known as sweet and cold, and it promotes urination and reduce edema by reducing heat from the lungs and soothe asthma. In the present study, anti-apoptotic mechanism of MRC in middle cerebral artery occlusion (MCAO) model in mice. Methods : Two-hundred grams of MRC was extracted with methanol at room temperature for 5 days, and this was repeated one time. After filtration, the methanol was removed using vacuum evaporator, then stored at $-20^{\circ}C$ until use. C57BL/6 male mice were housed in an environment with controlled humidity, temperature, and light cycle. In order to determine beneficial effects of MRC on ischemia induced brain damage, infarct volume, neurological deficit scores, activities of several apoptosis-related proteins such as caspase-8, -9, Bcl-xL in MCAO-induced brains of mice were analyzed. Mice in MRC-treated groups were orally administered 30, 100, or 300 mg/kg of body weight for three consecutive days before commencing the MCAO procedure. Results : Pre-treatment of MRC significantly reduced infarct volume in MCAO subjected mice applied with 300 mg/kg of MRC methanol extract, and MRC effectively inhibited Bcl-xL reduction and caspase-9 activation caused by MCAO-induced brain damage. Conclusions : MRC showed neuro-protective effects by regulating apoptosis-related protein signals, and it can be a potential candidate for the therapy of ischemia-induced brain damage.

• Imaging Science in Dentistry
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• v.33 no.2
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• pp.97-105
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• 2003

Purpose : To evaluate the effect of all-trans-retinoic acid (ATRA) on the radiosensitivity of normal human oral keratinocyte (NHOK). Materials and methods: Relative cell survival fraction including SF2 (survival fraction at 2 Gy) was calculated on the basis of colony formation assay. Data were fitted to the linear-quadratic model to establish the survival curve and calculate α and β values. Using flow cytometry at 1, 2, 3, 4, and 5 days after exposure to 2 and 10 Gy irradiation, cell cycle arrest and apoptosis were analysed. To understand the molecular mechanism of the radiosensitization of ATRA on NHOK, proteins related with apoptosis and cell cycle arrest were investigated by Western blot analysis. Results: Treatment with ATRA resulted in a significant decrease of SF2 value for NHOK from 0.63 to 0.27, and increased α and β value, indicating that ATRA increased radiosensitivity of NHOK. ATRA increased LDH significantly, but increasing irradiation dose decreased LDH, suggesting that the radiosensitizing effect of ATRA is not directly related with increasing cell necrosis by ATRA. ATRA did not induce appotosis but increased G2 arrest after 10 Gy irradiation, implying that the increased radiosensitivity of NHOK may be due to a decrease in mitosis casued by increasing G2 arrest. ATRA inhibited the reduction of p53 at 3 days after l0Gy irradiation and increased p21 at 1 day after 10 Gy irradiation. Further study is required to determine the precise relationship between this effect and the radiosensitizing effect of A TRA. Conclusion: These results suggested that ATRA increase radiosensitivity by inhibiting mitosis caused by increasing G2 arrest.

• Journal of the Korean GEO-environmental Society
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• v.15 no.6
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• pp.67-73
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• 2014

Landslide disasters including debris flows are the one of the most frequent natural disasters in Korea, and losses of lives and property damages due to these catastrophic events have been increased every year. Various mitigation programs and related policies have been conducted in order to respond and prepare landslide disasters. Most landslide reduction programs are, however, focused on recovery actions after the disasters and lead to unrealistic consequences to the affected people and their properties. The main objective of this study, therefore, is to evaluate the landslide hazard based on the identification of geomorphological features, which is for the preparedness of the landslide disasters. Two methodologies, SINMAP and vector dispersion analyses are used to simulate those characteristics where landslides are actually located. Results showed that both methods well discriminate geomorphic features between stable and unstable domains. This proves that geomorphological characteristics well describe a relationship with the existing landslide hazard. SINMAP analysis which is based on the consecutive model considering external factors like infiltration is well identify the landslide hazard especially for debris flow type landslides rather than vector dispersion focusing on a specific area. Combining with other methods focusing specific characteristics of geomorphological feature, accurate landslide hazard assessments are implemented.

• Journal of the Korean Society of Safety
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• v.25 no.6
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• pp.34-39
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• 2010

The purpose of this study is to suggest objective evaluation model as a plan to utilize as opportunity in establishing judgment standard of mutual inspection criteria and to upgrade inspection ability by reviewing and analyzing level of danger and importance in advance based on inspection results of inspection institutions regarding tower cranes used in construction fields. Tower crane is a mechanical device transporting construction supplies and heavy materials to places over 20~150M high from the ground for the period ranging from a short time of 2~3 months to two years after being installed in construction sites in vicinity of buildings or structures and is an important facility indispensable for construction sites. However, since use period after installation is short and professional technical ability of technicians working on-site about of tower crane is poor, systematic and quantitative safety management is not carried out As a part of researches on procedure of RBI(Risk Based Inspection) possible to apply to Knowledge Based System based on knowledge and experiences of experts as well as to tower cranes for solving these problems, quantitative RPN(Risk Priority Number) was applied to RPN utilizing technique of FMEA(Failure Mode and Effect Analyses). When general RBI 80/20 Rule was applied parts with high level of risks were found out as wire rope, hoist up/down safety device, reduction gear, and etc. However, since there are still many insufficient parts as risk analyses of tower crane were not established, it is necessary for experts with sufficient experiences and knowledge to supplement active RBI techniques and continuous researches on tower cranes by sharing and setting up data base of important information with this study as a starting point.

• Korean Journal of Construction Engineering and Management
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• v.13 no.5
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• pp.25-34
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• 2012

It has been five years since the Post-Construction Sale System of Housing was introduced. The purpose of this study is to identify objectives and effects of the Post-Construction Sale System of Housing and analyze change of profitability at different sales time from a supplier's point of view. Apartment buildings construction projects performed in Seoul are used for the case study. The present value of sales revenues, sensitivity and the present value of expected sales prices are analyzed. According to the findings, first, profits made from a Pre-construction sales system was 5.1%~6.2% higher than those from a Post-construction sales system. Among four plans of a Pre-construction sales system (A, B, C and D plan), sales revenue from the A plan, which takes a deposit at the time of starting construction, was the greatest. Second, increase of the rate of discount and decrease of sales revenues are in direct proportion. The bigger rate of discount leads actual reduction of sales revenues. Third, for the present value of sales revenues reflecting change in basic model construction cost, a Pre-construction sales system showed a little higher than that of a Post-construction sales system by approximately 2%. It should be known that this study suggests profitability of Pre-and Post-construction sales system by clearly measuring them in the supplier's point of view and calculates sales revenues, considering change of a sale price following change of sales time.