• Title/Summary/Keyword: Model Organism

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ON THE PROBABILITY OF GENOTYPES IN POPULATION GENETICS

  • Choi, Won
    • Korean Journal of Mathematics
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    • v.28 no.1
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    • pp.1-7
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    • 2020
  • A partition X describes that there exists αi kinds of alleles occurring i loci for each i. All genes have multiple alleles, i.e., they exist in more than two allelic forms, although any one diploid organism can carry no more than two alleles. The number of possible genotypes in a multiple allel series depends on the number of alleles. We will deal with an n locus model in which mutation and gene conversion are taken into consideration. In this paper, we firstly find the probability pn(x) of genotype $$p_{n+1}(x)=p_n(x){\sum\limits_{k=1}^{r}}q_{kx}p_n(k)$$ with the rates of mutation and gene conversion. Also we find the probability of genotype without the rates of mutation and gene conversion and we apply this probability to two examples.

Consumers' Willingness to Pay for Price Increases by the Expansion of GMO Labeling (GMO 표시제 강화로 인한 물가 상승시 소비자의 지불 의향)

  • Han, Jae-Hwan
    • The Korean Journal of Food And Nutrition
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    • v.22 no.3
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    • pp.338-344
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    • 2009
  • This study analyzed consumers' willingness to pay for price increases to avoid the purchase of GM foods by the expansion of GMO labeling. The subjects were asked about their knowledge of GM, concerns of potential hazards, and sources of obtained GM information. The logit model was employed and marginal effects were calculated to interpret the results. The results showed that consumers who perceived the safety of GM technology were less likely to pay for price increases, while consumers who had concerns about GM foods were more likely to pay. In addition, the study demonstrated that consumers residing in urban areas and with low levels of education and income were also less likely to pay for price increases.

Spot the difference: Solving the puzzle of hidden pictures in the lizard genome for identification of regeneration factors

  • Chung, Jin Woong
    • BMB Reports
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    • v.49 no.5
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    • pp.249-254
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    • 2016
  • All living things share some common life processes, such as growth and reproduction, and have the ability to respond to their environment. However, each type of organism has its own specialized way of managing biological events. Genetic sequences determine phenotypic and physiological traits. Based on genetic information, comparative genomics has been used to delineate the differences and similarities between various genomes, and significant progress has been made in understanding regenerative biology by comparing the genomes of a variety of lower animal models of regeneration, such as planaria, zebra fish, and newts. However, the genome of lizards has been relatively ignored until recently, even though lizards have been studied as an excellent amniote model of tissue regeneration. Very recently, whole genome sequences of lizards have been uncovered, and several attempts have been made to find regeneration factors based on genetic information. In this article, recent advances in comparative analysis of the lizard genome are introduced, and their biological implications and putative applications for regenerative medicine and stem cell biology are discussed.

How Background Music Affects Consumer Perception of Waiting Time? -A Mediating Role of Emotions-

  • Park, Jee-Sun;Stoel, Leslie D.
    • Journal of Fashion Business
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    • v.22 no.3
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    • pp.16-29
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    • 2018
  • The present study examines whether consumers' perception of waiting time and their behavioral intentions are influenced by the presence of background music in an online shopping environment. In particular, this study aims to explain the underlying mechanism for the effects of background music on consumers' perceived wait and behavioral intentions toward the online retailer by proposing the mediating role of emotions drawing on the Stimulus-Organism-Response (S-O-R) framework. A lab experiment was employed to test the hypotheses. A total of 102 college students were used for data analyses. Results show that the presence of music has a significant impact on participants' emotions, perceived waiting time, and approach behavior. Moreover, the findings show that pleasure and the perceived waiting time serve as mediators in the relationship between the presence of music and approach behavior. Implications of the model for theory, practice, and further research are discussed.

Sole and Combined Usage of Ultra-sonication and Hydrogen Peroxide as Mitigation Techniques of Bio-fouling

  • Haque, Md. Niamul;Kwon, Sung-hyun
    • Journal of Environmental Science International
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    • v.25 no.10
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    • pp.1397-1405
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    • 2016
  • Mussels are stubborn organism attached to solid substrate by byssus threads and caused operational problems in utility of power generating stations. Sole and combined usage of ultrasonic (28 kHz- and 42 kHz- frequencies) and hydrogen peroxide ($H_2O_2$) has studied for control of blue mussel larvae and adult stage in seawater condition. A theoretical wo rking model using disinfection (Chick and Watson type) approaches is presented based on helpful results of experiments. This study also demonstrate that the combined treatment (ultra-sonication with $H_2O_2$) is overall highly efficient than individual treatment would, but on the basis of exposure time, the ultra-sonication was the most efficient among them. Therefore the development of sole and combined technique might be effective practical mitigation strategy against mussel attachment for water handling facilities.

Effects of Ginseng Saponin on the Regu lately Properties of Malate Dehydrogenase from Pigeon Breast Muscle (인삼사포닌이 비둘기 가슴근육으로부터 분리된 Malate Dehydrogenase의 조절기능에 미치는 영향)

  • Kim, Du-Ha;Sin, Mun-Hui;Hong, Sun-Geun
    • Journal of Ginseng Research
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    • v.7 no.1
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    • pp.80-87
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    • 1983
  • In an endeavour to elucidate effects of ginseng on some characteristics of enzymes, malate dehydrogenase (EC 1.1.1.37) was chosen as a model enzyme and effects of ginseng saponin on the enzyme such as optimum pH, product inhibition, optimum temperature and the activity was investigated. The product inhibition by NADH-a reaction product of the enzyme-was increased 33% by 0.3% ginseng saponin. And the optimum pH of the enzyme was 8.3 but in the presence of 0.3% ginseng saponin it increased to 8.5. The enzyme activity and the optimum temperature was not affected by ginseng saponin in the concentration of 1.0% and 0.3%, respectively. In this work, the possibility of contribution of ginseng saponin to the adaptogen activity is suggested; Potentiation of the regulatory activity of an enzyme may contribute to the normalization of the physiological state and consequently may increase the nonspecific resistance of an organism.

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Survival assays using Caenorhabditis elegans

  • Park, Hae-Eun H.;Jung, Yoonji;Lee, Seung-Jae V.
    • Molecules and Cells
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    • v.40 no.2
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    • pp.90-99
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    • 2017
  • Caenorhabditis elegans is an important model organism with many useful features, including rapid development and aging, easy cultivation, and genetic tractability. Survival assays using C. elegans are powerful methods for studying physiological processes. In this review, we describe diverse types of C. elegans survival assays and discuss the aims, uses, and advantages of specific assays. C. elegans survival assays have played key roles in identifying novel genetic factors that regulate many aspects of animal physiology, such as aging and lifespan, stress response, and immunity against pathogens. Because many genetic factors discovered using C. elegans are evolutionarily conserved, survival assays can provide insights into mechanisms underlying physiological processes in mammals, including humans.

The Role of Lozenge in Drosophila Hematopoiesis

  • Koranteng, Ferdinand;Cha, Nuri;Shin, Mingyu;Shim, Jiwon
    • Molecules and Cells
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    • v.43 no.2
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    • pp.114-120
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    • 2020
  • Drosophila hematopoiesis is comparable to mammalian differentiation of myeloid lineages, and therefore, has been a useful model organism in illustrating the molecular and genetic basis for hematopoiesis. Multiple novel regulators and signals have been uncovered using the tools of Drosophila genetics. A Runt domain protein, lozenge, is one of the first players recognized and closely studied in the hematopoietic lineage specification. Here, we explore the role of lozenge in determination of prohemocytes into a special class of hemocyte, namely the crystal cell, and discuss molecules and signals controlling the lozenge function and its implication in immunity and stress response. Given the highly conserved nature of Runt domain in both invertebrates and vertebrates, studies in Drosophila will enlighten our perspectives on Runx-mediated development and pathologies.

The complete mitochondrial genome of Arabidopsis thaliana (Brassicaceae) isolated in Korea

  • PARK, Jongsun;XI, Hong;KIM, Yongsung
    • Korean Journal of Plant Taxonomy
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    • v.51 no.2
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    • pp.176-180
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    • 2021
  • Arabidopsis thaliana (L.) Heynh. is a small plant species that serves as a model organism of plant biology and genetics. Here, we present the first complete mitochondrial genome of Korean A. thaliana natural isolate (named as 180404IB4), which is 368,875 bp long and contains 58 genes (33 protein-coding genes, 22 tRNAs, and three rRNAs), with a GC ratio of 44.8%. Sixty-four single-nucleotide polymorphisms and 11 insertion and deletion regions (1,089 bp in length) are identified against the Col-0 ecotype, showing one large insertion of 1,069 bp without structural variation. Phylogenetic trees constructed from 30 conserved genes indicate that the 180404IB4 mitochondrial genome is clustered with Col-0 and three East Asian ecotypes.

The Impact of Live Commerce Features and Situational Factors on Participation Intention in Tourism Live Commerce

  • Sheng, Congyi;Yang, Sung-Byung;Kim, Sung-Eun
    • The Journal of Information Systems
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    • v.33 no.2
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    • pp.237-264
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    • 2024
  • Purpose This study explores the impact of tourism live commerce on consumer participation intention. Utilizing Stimulus-Organism-Response (S-O-R) framework and situation theory, the study is to identify the features and situational factors of tourism live commerce and to investigate their impact on flow experience, perceived value, and participation intention. Design/methodology/approach A theoretical model is developed and validated through a survey, adopting PLS-SEM approach. A self-administered questionnaire was developed and distributed via Wenjuanxing, the largest online survey platform in China, in October 2022, resulting in 361 valid responses. Findings The results reveal significant effects of features and situational factors of tourism live commerce on consumer behavior, enhancing the understanding of tourism live commerce and extending the S-O-R framework in this context. The study offers both theoretical contributions and practical implications, providing valuable insights for managers to improve consumer engagement in tourism live commerce.