• Title/Summary/Keyword: Model Course

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Kinetics of Drying Shiitake Mushroom, Lentinus edodes sanryun No. 1 (표고버섯의 열풍건조속도론(熱風乾燥速度論)에 관한 연구(硏究))

  • Cho, Duk-Bong;Kim, Dong-Pil;Choi, Choon-Soon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.10 no.1
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    • pp.53-60
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    • 1981
  • Dehydration phenomena has been studied for the shiitake mushroom Lentinus edodes sanryun No.1, through which examine the effect of temperature and air velocity and derivation of its kinetics. Temperature effect for the dehydration rate constant were examined under the constant air velocity (1.5m/sec) with the variation of temperature from $40^{\circ}C$ to $55^{\circ}C$. Water content were reduced exponentially with the course of time and calculated dehydration rate constant values varies with temperature with an Arrhenius-type relationship, which had been expected in the chemical reaction kinetics. Influence of air velocity for the dehydration rate constant under the constant temperature $(45^{\circ}C)$ showed interesting results. For the range 1.0m/sec to 2.0m/sec, dehydration rate constant values are increased with the air velocity, but for the 2.0 to 3.1m/sec, dehydration rate constant values are decreased which were caused by case hardening. One of the selected conditions in the optimal dehydration range, temperature $50^{\circ}C$, air velocity 2m/see, and its measured humidity 38-41%, mathematical model of dehydration curve and dehydration rate equations were developed and the resulting kinetic models were X=6.94 $e^{-0.345t}$ and dx/dt = -2.39 $e^{-0.345t}$

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Estimation of Cardinal Temperatures for Germination of Seeds from the Common Ice Plant Using Bilinear, Parabolic, and Beta Distribution Models

  • Cha, Mi-Kyung;Park, Kyoung Sub;Cho, Young-Yeol
    • Horticultural Science & Technology
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    • v.34 no.2
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    • pp.236-241
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    • 2016
  • The common ice plant (Mesembryanthemum crystallinum L.) has some medicinal uses and recommended plant in closed-type plant factory. The objective of this study was to estimate the cardinal temperatures for seed germination of the common ice plant using bilinear, parabolic, and beta distribution models. Seeds of the common ice plant were germinated in the dark in a growth chamber at four constant temperatures: 16, 20, 24, and $28^{\circ}C$. For this, four replicates of 100 seeds were placed on two layers of filter paper in a 9-cm petri dish and radicle emergence of 0.1 mm was scored as germination. The times to 50% germination were 4.3, 2.5, 2.0, and 1.8 days at 16, 20, 24, and $28^{\circ}C$, respectively, indicating that the germination of this warm-weather crop increased with temperature. Next, the time course of germination was modeled using a logistic function. For the selection of an accurate model, seeds were germinated in the dark at constant temperatures of 6, 12, 32, and $36^{\circ}C$. Germination started earlier and increased rapidly at temperatures above $20^{\circ}C$. The minimum, optimal, and maximum temperatures were estimated by regression of the inverse of time to 50% germination rate, as a function of the temperature gradient. The different functions estimated differing minimum, optimal and maximum temperatures, with 5.7, 27.7, and $36.5^{\circ}C$, respectively for the bilinear function, 13.4, 25.0, and $36.6^{\circ}C$, respectively, for the parabolic function and 7.8, 25.9, and $36.0^{\circ}C$, respectively, for the beta distribution function. The models estimated that the inverse of time to 50% germination rate was 0 at 6 and $36^{\circ}C$. The observed final germination rates at 12 and $32^{\circ}C$ were 62 and 97%, respectively. Our data show that a beta distribution function provides a useful model for estimating the cardinal temperatures for germination of seed from the common ice plant.

Engraftment of Human Mesenchymal Stem Cells in a Rat Photothrombotic Cerebral Infarction Model : Comparison of Intra-Arterial and Intravenous Infusion Using MRI and Histological Analysis

  • Byun, Jun Soo;Kwak, Byung Kook;Kim, Jae Kyun;Jung, Jisung;Ha, Bon Chul;Park, Serah
    • Journal of Korean Neurosurgical Society
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    • v.54 no.6
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    • pp.467-476
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    • 2013
  • Objective : This study aimed to evaluate the hypotheses that administration routes [intra-arterial (IA) vs. intravenous (IV)] affect the early stage migration of transplanted human bone marrow-derived mesenchymal stem cells (hBM-MSCs) in acute brain infarction. Methods : Male Sprague-Dawley rats (n=40) were subjected to photothrombotic infarction. Three days after photothrombotic infarction, rats were randomly allocated to one of four experimental groups [IA group : n=12, IV group : n=12, superparamagnetic iron oxide (SPIO) group : n=8, control group : n=8]. All groups were subdivided into 1, 6, 24, and 48 hours groups according to time point of sacrifice. Magnetic resonance imaging (MRI) consisting of T2 weighted image (T2WI), $T2^*$ weighted image ($T2^*WI$), susceptibility weighted image (SWI), and diffusion weighted image of rat brain were obtained prior to and at 1, 6, 24, and 48 hours post-implantation. After final MRI, rats were sacrificed and grafted cells were analyzed in brain and lung specimen using Prussian blue and immunohistochemical staining. Results : Grafted cells appeared as dark signal intensity regions at the peri-lesional zone. In IA group, dark signals in peri-lesional zone were more prominent compared with IV group. SWI showed largest dark signal followed by $T2^*WI$ and T2WI in both IA and IV groups. On Prussian blue staining, IA administration showed substantially increased migration and a large number of transplanted hBM-MSCs in the target brain than IV administration. The Prussian blue-positive cells were not detected in SPIO and control groups. Conclusion : In a rat photothrombotic model of ischemic stroke, selective IA administration of human mesenchymal stem cells is more effective than IV administration. MRI and histological analyses revealed the time course of cell migration, and the numbers and distribution of hBM-MSCs delivered into the brain.

The Roles and Importance of Critical Evidence (CE) and Critical Resource Models (CRMs) in Abductive Reasoning for Earth Scientific Problem Solving (지구과학 문제 해결을 위한 귀추적 추론에서 결정적 증거와 결정적 자원 모델의 역할과 중요성)

  • Oh, Phil Seok
    • Journal of Science Education
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    • v.41 no.3
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    • pp.426-446
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    • 2017
  • The purpose of this study was to analyze undergraduate students' reasoning for solving a problem about a rock and investigate the roles and importance of critical evidence (CE) and critical resource models (CRMs) in abductive reasoning. Participants were 20 senior undergraduate students enrolled in a science major course in a university of education. They were asked to abductively infer geologic processes of sedimentary rocks having a lot of holes and represent them with models. Their reasoning were analyzed according to a scheme for modeling-based abductive reasoning. As a result, successful student reasoning was characterized by using a diversity of grains and lots of holes as CE, activating the sedimentary rock formation and weathering as CRMs, and combining the CRMs into a scientifically sound explanatory model (SSEM). By contrast, in the reasoning unsuccessful in proposing a SSEM, students activated the igneous rock (basalt) formation and deposition as resource models (RMs) based on the evidence of the holes in the rocks and diverse grains, respectively, and used the RMs to construct their own explanatory models (EMs). It was suggested that to construct SSEMs to solve earth scientific problems about rocks, students need to know what could be CE in a particular problem situation, take an integrative or systemic approach to a rock problem, use multiple RMs, and evaluate RMs or EMs in light of evidence.

A Study on the Development of Curriculum for the Navigation Science Department of the Kenya Maritime College (케냐해양대학 항해학과 교과과정의 개발에 관한 연구)

  • Hong, Joon-Kee;Jung, Yun-Chul
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.22 no.6
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    • pp.679-687
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    • 2016
  • In developing countries, the establishment of maritime colleges and the training of excellent merchant marine officers can greatly impact on the growth of the marine industry in a given country. The project to establish the Kenya Maritime College ('KMC') has been driven by the Kenyan government, which has been challenged by the growth of the marine industry in Korea. This study aims to the development of curriculum for the navigation science department of the KMC. To do this, firstly the Kenyan environments was surveyed. Then, IMO maritime education requirements, IMO model courses and curriculums from the navigation science departments of major maritime universities around the world were reviewed. Lastly, based on these surveys and reviews, curriculum for the navigation science department of the KMC was developed. This curriculum is comprised of an educational course that requires a total of 5 years of study, including 1 year of on-board training and a total of 200 credit hours (20 credit hours per semester). Although this curriculum has been developed to fit the environments of Kenya, it is expected to offer a point of reference for similar studies in other countries with the goal of standardizing maritime education internationally.

A Study on Development of Job-based Expert Training Model for International Maritime Dangerous Goods (직무기반 국제해상위험물 전문교육 모델 개발에 관한 연구)

  • Lee, Hong-Hoon;Rim, Geung-Su;Seo, Hye-Kyung;Keum, Jong-Soo;Kim, Chol-Seong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.19 no.6
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    • pp.649-657
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    • 2013
  • In this study, for a proposal of job-based IMDG code expert training model, the training cases of other countries were analyzed comparatively and a questionnaire-survey was conducted to find the needs of workers. As results of comparative analysis, various curriculums were operated by jobs of workers in USA and by kinds of dangerous goods or vehicles in UK, but a common curriculum was provided for various jobs of workers in Korea. It was analyzed that current domestic curriculum is not efficient, and the respondents demand expansion of training including provision of information via web-site as results of questionnaire survey. Therefore, in conclusion, after the shore workers were classified into three groups(on-site worker, office worker, & carrying worker), the customized training program of each group was suggested. Furthermore, this study proposed the regional operation of training course to meet regional demand on education including establishment of on-line curriculums.

Route Changes of Our Policy the Public Rental Housing -of Nest Housing and Happy Homes- (우리나라 공공임대주택정책의 경로변화 -보금자리 주택, 행복주택을 중심으로-)

  • Kim, Bog-Sig;Ryu, Ji-Seong
    • The Journal of the Korea Contents Association
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    • v.16 no.9
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    • pp.170-184
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    • 2016
  • The research is our public rental housing policy are 'Why' Did you no choice but to make the route changes, according to previous governments neo-institutional one fine history of care institutions, Historical analysis method and historical comparison system was complementary to the borders of the principle of hacke to appear (248 hacker, 2004 :) that the path to the model attempts to analyze a mix of evolution. Our country has a high degree of exodus due to industrialization and urbanization have caused and here, by means of side effects to housing was becoming serious social problems. Has this to solve housing problems governments have any policy to take a look at the latest. 5, 16 5,16 Military Coup caused by the advent of the Third Republic ; lack of legitimacy of the regime established, the Korea Housing Corporation randomness that for over the cracks and a consensus on the critical period of Public Rental Housing begins to engage in further studies in this study reported paths of Lee Myung-bak administration during the course of evolution 'of nest housing', and government 'happy homes', Park Geun-hye, a diagnose and address the state of the public rental housing policy by comparison, the next of Public Rental Housing A desirable destination of the study to present.

Changes of the liver volume and the Child-Pugh score after high dose hypofractionated radiotherapy in patients with small hepatocellular carcinoma

  • Kim, Young Il;Park, Hee Chul;Lim, Do Hoon;Park, Hyo Jung;Kang, Sang Won;Park, Su Yeon;Kim, Jin Sung;Han, Youngyih;Paik, Seung Woon
    • Radiation Oncology Journal
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    • v.30 no.4
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    • pp.189-196
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    • 2012
  • Purpose: To investigate the safety of high dose hypofractionated radiotherapy (RT) in patients with small hepatocellular carcinoma (HCC) in terms of liver volumetric changes and clinical liver function. Materials and Methods: We retrospectively reviewed 16 patients with small HCC who were treated with high dose hypofractionated RT between 2006 and 2009. The serial changes of the liver volumetric parameter were analyzed from pre-RT and follow-up (FU) computed tomography (CT) scans. We estimated linear time trends of whole liver volume using a linear mixed model. The serial changes of the Child-Pugh (CP) scores were also analyzed in relation to the volumetric changes. Results: Mean pre-RT volume of entire liver was 1,192.2 mL (range, 502.6 to 1,310.2 mL) and mean clinical target volume was 14.7 mL (range, 1.56 to 70.07 mL). Fourteen (87.5%) patients had 4 FU CT sets and 2 (12.5%) patients had 3 FU CT sets. Mean interval between FU CT acquisition was 2.5 months. After considering age, gender and the irradiated liver volume as a fixed effects, the mixed model analysis confirmed that the change in liver volume is not significant throughout the time course of FU periods. Majority of patients had a CP score change less than 2 except in 1 patient who had CP score change more than 3. Conclusion: The high dose hypofractionated RT for small HCC is relatively safe and feasible in terms of liver volumetric changes and clinical liver function.

Screening for Patients with Non-small Cell Lung Cancer Who Could Survive Long Term Chemotherapy

  • Wu, Xue-Yan;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.647-652
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    • 2015
  • Background: Lung cancer was one of the most common cancers in both men and women all over the world. In this study, we aimed to clarify who could survive after long term chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). Methods: We enrolled 186 patients with stage IV NSCLC after long term chemotherapy from Jun 2006 to Nov 2014 diagnosed in Jiangsu Cancer Hospital. Multiple variables like age, gender, smoking, histology of adenocarcinoma and squamous-cell cancer, number of metastatic sites, metastatic sites (e.g. lung, brain, bone, liver and pleura), hemoglobin, lymphocyte rate (LYR), Change of LYR during multiple therapies, hypertension, diabetes, chronic bronchitis, treatments (e.g.radiotherapy and targeted therapy) were selected. For consideration of factors influencing survival and response for patients with advanced NSCLC, logistic regression analysis and Cox regression analysis were used in an attempt to develop a screening module for patients with elevated survival after long term chemotherapy become possible. Results: Of the total of 186 patients enrolled, 69 survived less than 1 year (short-term group), 45 one to two years, and 72 longer than 3 years (long-term group). For logistic regression analysis, the short-term group was taken as control group and the long-term group as the case group. We found that age, histology of adenocarcinoma, metastatic site (e.g. lung and liver), treatments (e.g. targeted therapy and radiotherapy), LYR, a decreasing tendency of LYR and chronic bronchitis were individually associated with overall survival by Cox regression analysis. A multivariable Cox regression model showed that metastatic site (e.g. lung and liver), histology of adenocarcinoma, treatments (e.g. targeted therapy and radiotherapy) and chronic bronchitis were associated with overall survival. Thus metastatic site (e.g. lung and liver) and chronic bronchitis may be important risk factors for patients with advanced NSCLC. Gender, metastatic site (e.g. lung and liver), LYR and the decreasing tendency of LYR were significantly associated with long-term survival in the individual-variable logistic regression model (P<0.05). On multivariate logistic regression analysis, gender, metastatic site (e.g. lung and liver) and the decreasing tendency of LYR associated with long-term survival. Conclusions: In conclusion, female patients with stage IV adenocarcinoma of NSCLC who had decreasing tendency of LYR during the course therapy and had accepted multiple therapies e.g. more than third-line chemotherapy, radiotherapy and/or targeted therapy might be expected to live longer.

Evaluation of the National Train-the-Trainer Program for Hospice and Palliative Care in Korea

  • Kang, Jina;Yang, Eunbae B.;Chang, Yoon Jung;Choi, Jin Young;Jho, Hyun Jung;Koh, Su Jin;Kim, Won Chul;Choi, Eun-Sook;Kim, Yeol;Park, Sung-Min
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.501-506
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    • 2015
  • Background: To evaluate the effectiveness of the National Train-the-Trainers Program for Hospice and Palliative Care Experts (TTHPC) sponsored by the National Cancer Center of Korea between 2009 and 2012. This program was developed to improve the teaching skills of those in the field of hospice and palliative care (HPC). Materials and Methods: Training was offered in eight 1-day sessions between 2009 and 2012. The effect of the program was measured using Kirkpatrick's model of educational outcomes. First, levels 1 and 2 were evaluated immediately after the 1-day program (n=120). In 2012, the level-3 evaluation test was administered to trainers who offered at least one HPC training (n=78) as well as to their trainees (n=537). Results: The level-1 evaluation addressed participant reactions to and satisfaction with the program. Participants (n=120) were generally satisfied with the content, the method, and the overall course (mean range: 3.94-4.46 on a five-point Likert scale). The level-2 evaluation (learning) showed that participants gained knowledge and confidence related to teaching HPC (4.24 vs. 4.00). The level-3 evaluation (behavioral), which assessed trainers' application of teaching skills to HPC, showed that trainees rated the teaching methods of trainers (mean range: 4.03-4.08) more positively than did trainers (p<0.05). Female trainers were more likely than were male trainers to plan sessions in consideration of their trainees' characteristics (4.11 vs. 3.58; p<0.05), and nurse trainers were more likely than physician trainers to use a variety of instructional methods (4.05 vs. 3.36; p<0.05) Conclusions: We conducted systematic evaluations based on Kirkpatrick's model to assess the effectiveness of our train-the-trainers program. Our educational program was practical, effective, and followed by our HPC experts, who needed guidance to learn and improve their clinical teaching skills.