• Bulletin of the Korean Chemical Society
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• v.31 no.7
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• pp.1848-1858
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• 2010

Phenylaminopyrimidines represent a large group of new selective anticancer agents, the majority of which exert their action through the inhibition of specific kinases. In this study, a new series of N-substituted-2-aminopyrimidines has been designed and synthesized. A selected group of the synthesized derivatives was screened at a single dose concentration of 10 ${\mu}M$ over a panel of 60 cancer cell-lines. Compound 12e has showed great inhibitory and strong lethal effect over almost all of the 60 cell-lines and accordingly was further tested in a 5-dose testing mode to determine its $IC_{50}$ values, where it showed great efficacies with intermediate potencies over the tested cell-lines. The compound was also tested over a panel of 52 kinases to explore its kinase inhibitory profile, and was found to be a selective but moderate inhibitor over FLT3 kinase.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.7
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• pp.706-712
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• 2004

This paper presents the design technique of output multiplexer(OMUX) for the Ka-band satellite transponder. Output multiplexer consists of low-pass filter(LPF), channel filter and manifold. Channel filters adopt dual-mode technique in design for mass and volume reduction and frequency response of channel filters is 4-pole elliptic response for high frequency selectivity. w-pass filters are designed to be of 13th order corrugated type for high rejection characteristic over reception band of satellite transponder. After initial design of channel filters and manifold, we optimized only a few design parameters for fast and easy optimization instead of optimizing all the design parameter. Measured results of a realized output umltiplexer for Ka-band satellite transponder show good agreement with the computed ones.

• Journal of electromagnetic engineering and science
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• v.9 no.3
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• pp.164-173
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• 2009

In this paper, two new circuit structures for European and U.S. ultra-wide band(UWB) bandpass filters(BPFs) with sharp roll-off characteristics are introduced. We show first that the ultra-wide bandpass property is obtained from a $\lambda$/4 open T resonator with a capacitively coupled $\lambda$/4 short-circuited line, which provides two attenuation poles at lower and upper cutoff frequencies. Then, two identical capacitively coupled input/output lines, which can be $\lambda$/4-length open ends or $\lambda$/2-length short ends, with the T-resonator, are adopted to suppress lower and higher frequency components outside of the pass band. There is coupling between the input and output lines providing two additional transmission zeros in the lower and upper transition bands of the filter. Since the coupling between the T-resonator with the $\lambda$/4 short-circuited line and the input/output lines limits the bandwidth of the filter to the European UWB band, both the $\lambda$/4 short-circuited line and the input/output lines are inserted between the two stacked T-resonators for the U.S. UWB band. The filter structures are simulated with ADS and HFSS and realized with low-temperature co-fired ceramic(LTCC) green tape which has the dielectric constant of 7.8. Measurement results agree well with HFSS simulation results.

• Natural Product Sciences
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• v.14 no.3
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• pp.152-155
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• 2008

An HPLC-ESI-MS method has been developed to identify and quantify two main tetracyclic triterpenes, alisol B 23-acetate and alisol C 23-acetate in the Alismatis Rhizoma (Taeg-Sa). The relative distribution of the two triterpenes in the methanolic extract of commercially available Alismatis Rhizoma was established by selective ion monitoring (SIM) mode via electrospray ionization (ESI) source. Regression equations revealed good linear relationship, and the correlation coefficients were 0.999 and 0.998 for alisol B 23-acetate and alisol C 23-acetate, respectively, between the peak areas of the components and their concentration in a range of $0.06-2.0{\mu}g/mL$. It was found that there were significant differences in the amount of alisol B 23-acetate and alisol C 23-acetate between Korean and Chinese origins. The results showed that this method could be used to identify the two components in Alismatis Rhizoma with high sensitivity and selectivity.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.4 no.3
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• pp.565-573
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• 2000

In this paper, a interdigital microstrip bandpass filter is designed. A interdigital microstrip bandpass filter has many advantages such as insertion return loss, lower return loss, higher frequency selectivity and smaller in size in comparison with the conventional coupled line filter. A interdigital microstrip bandpass filter consists of quasi TEM-mode strip line resonators between parallel ground plant. Each resonator element is a quarter wavelength long of the center frequency and is short circuited at one end and open circuited at the other end. In the filter design, Ensemble software is used. Experimental results show that the bandwidth of interdigital microstrip bandpass filter is 2.52GHz, insertion loss is -1.8dB and return loss is -17.0dB at 11.20Hz.

• 한국신재생에너지학회:학술대회논문집
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• 2009.06a
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• pp.773-776
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• 2009

In this paper, new concept of the diesel fuel processing is introduced for the stable operation of solid oxide fuel cells (SOFCs). Heavier hydrocarbons than $CH_4$, such as ethylene, ethane, propane, and etc., induce the carbon deposition on anode of SOFCs. In the reformate of heavy hydrocarbons (diesel, gasoline, kerosene, and JP-8), concentration of ethylene is usually higher than low hydrocarbons such as ethane, propane, and butane. So, removal of low hydrocarbons (over C1-hydrocarbons), especially ethylene, at the reformate gases is important for stable operation of SOFCs. New methodology as named "post-reformer" is introduced for removing the low hydrocarbons at the reformate gas stream. Catalyst of the NECS-PR4 is selected for post-reforming catalyst because the catalyst of NECS-PR4 shows the high selectivity for removing low hydrocarbons and achieving the high reforming efficiency. The diesel reformer and post-reformer are continuously operated for about 200 hours as integrated mode. The reforming performance is not degraded and low hydrocarbons in the diesel reformate are completely removed.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2012.03a
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• pp.29-29
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• 2012

Rhodamine chromophore/fluorophore have been attracted to many researchers due to its excellent photophysical properties. In this study, we have designed and synthesized a strong emissive fluorescent dye chemosensor for toxic elements. A rhodamine-based sensor was prepared by incorporation the rhodamine fluorophore and several functional host groups with high affinity to hazardous metal and anion. This sensor shows a high selectivity and an excellent sensitivity and is a dual-responsive colorimetric and fluorescent metal/anion-specific sensor. In addition, the 1:1 binding mode was proposed based on Job's plot method. Finally, computational calculation was simulated and calculated to approach for HOMO/LUMO of this dye chemosensor.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.28A no.11
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• pp.902-909
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• 1991

A reproducible selective dry etch process of GaAs/AlGaAs Heterostructures for High Electron Mobility Transistor(HEMT) Device fabrication is developed. Using RIE mode with $CCl_{2}F_{2}$ as the basic process gas, the observed etch selectivity of GaAs layer with respect to GaAs/$Al_{0.3}Ga_{0.7}$As is about 610:1. Severe polymer deposition problem, parialy generated from the use of $CCl_{2}F_{2}$ gas only, has been significantly reduced by adding a small amount of He gas or by $O_{2}$ plasma ashing after etch process. In order to obtain an optimized etch process for HEMT device fabrication, we com pared the properties of the wet etched Schottky contact with those of the dry etched one, and set dry etch condition to approach the characteristics of Schottky diode on wet etched surface. By applying the optimized etch process, the fabricated HEMT devices have the maximum transconductance $g_{mext}$ of 224 mS/mm, and have relatively uniform distribution across the 2inch wafer in the value of 200$\pm$20mS/mm.

• Journal of the Institute of Electronics and Information Engineers
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• v.54 no.5
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• pp.128-132
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• 2017

In this thesis, a BPF(band-pass filter) at the center frequency of 2.14GHz, and bandwidth of 20MHz is designed and implemented using high Q dielectric resonators with ${\varepsilon}_r=38$. The DR(dielectric resonator) is resonated by $TE_{01{\delta}}$-mode and it has a hole in the center of DR. The BPF consists of 6-poles dielectric resonators and the characteristic of elliptic function is obtained by non-adjacent coupling. It has the average insertion loss of 0.97dB and the return loss over 25dB in its passband. In this thesis, the frequency selectivity is more improved by the coupling characteristics between non-adjacent resonators than that of dielectric resonator filters with a Chebyshev response.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.37 no.4
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• pp.53-59
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• 2000

Based on the polarization selectivity of fiber-to-planar waveguide coupler, a novel fiber optic polarizer has been designed and fabricated. The large structural birefringence of a metal-clad planar waveguide enables the polarizer to have wide operating wavelength range. The polymer and gold were used for the guiding layer and cladding layer of the planar waveguide, respectively. The experimental results showed that either TE or TM polarized lightwave could be created by adjusting the thickness of planar waveguide. Operating wavelegth range satisfying more than 16㏈ polarization extinction ratio was 130nm. The average insertion loss of fabricated devices was order of 0.5㏈.