• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 추계학술대회
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• pp.838-841
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• 2012

본 논문에서는 온도변화에 따른 회로 손상이나 성능 저하를 피하기 위해서 회로 안에 내장할 수 있는 온도 센서 회로를 설계하였다. 일반적인 PTAT회로를 사용하여 온도감지를 하고, 스위치를 내장시켜 회로 동작이 불가능할 정도로 IC 내부 온도가 높을 때는 절전모드로 동작하게 하였다. 또한, 전류미러 및 캐스코드회로를 사용함으로서 전류 정합특성을 향상시켰다. 시뮬레이션 결과 $75^{\circ}C$일 경우 약 1V, $130^{\circ}C$일 경우 1.75V를 출력전압을 발생하였으며, 절전모드의 경우 0V~7uV까지 즉 거의 0V에 가까운 출력전압을 발생함을 확인 할 수 있었다.

• STI Policy Review
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• 제8권2호
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• pp.23-48
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• 2017

This article advocates for a Mode 3 science policy. Compared to the university research-based Mode 1 knowledge production system and the knowledge application-centric Mode 2 innovation system, Mode 3 can be defined as a system that integrates both Mode 1 and Mode 2-type knowledge production models. In this article, based on the major characteristics of the Mode 3 scientific knowledge production system, I agree with the advocates of Mode 3 that constructing a knowledge society requires an inclusive form of knowledge production and innovation system through the democratization of knowledge production as well as the promotion of social values. Moreover, the mechanisms for creating accountable innovation in the Mode 3 system should be given more attention from the science research and policy communities to make public policy for scientific and technological innovation more reflective of social changes. Similar to the ways that the Mode 1 and Mode 2 scientific knowledge production approaches have influenced the development of science policy models, the Mode 3 scientific knowledge production approach, or Mode 3 science, also has the potential to shape a new science policy model. I will refer to this as Mode 3 science policy. In an effort to conceptualize the democracy- and society-centric Mode 3 science policy model, I will articulate science policy strategies in four science policy domains in South Korea from the context of the Mode 3 science approach. These include (1) evaluation of publicly-funded research activities, (2) valorization of scientific knowledge (that is, enhancement of the value of scientific knowledge through governmental action), (3) development of a science policy decision-making support system, and (4) anticipatory foresight of science, technology and society. When adopting and implementing a Mode 3 science framework, one progressive change is to increase socially desirable innovation such as responsible innovation.

• Journal of Plant Biology
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• 제9권1_2호
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• pp.17-21
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• 1966

The mutual relationships of boron, Ca and sucrose were studied in relation to in vitro pollen growth and pollen bursting, by using conventient pollen from Crinum asiaticum for experiment. Crinum pollen are paticularly sensitive to Ca. Addition of very small amount of boron to cultural media was apparently synergistic to the action of sucrose and Ca in pollen germination and tube elongation. This action was extended to a higher level of boron concentraton. Combined application of boron, Ca and sucrose always gave the better results in pollen growth and protection against pollen bursting much more than when used singly. This indicated that there is a direct relationship between better growth of pollen and increased rigidity of pollen cell wall. A higher level of Ca concentration tended to increase bursting rate of pollen grains and decrease that of pollen tubes, while boron always depressed the rate of bursting. This was considered due to increased failure in pollen germination at high level of Ca that favors pollen tube elongation. The fact that Ca show an antagonistic effect on the suppressive action of high level of boron in pollen growth and shows different effect in response to pollen bursting from boron, suggested mode of Ca and boron action in the presence of sucrose is quiate different, although to increase in rigidity of pollen cell wall by them is in common nature. It was postulated therefore that Ca acts on pectins of pollen cell wall largely as "non-metabolic" and boron as "metabolic" promoter is pollen growth and protecting pollen bursting, since boron and Ca have common nature in strengthening the pollen cell wall but act differently.but act differently.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
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• pp.340-342
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• 2005

This paper describes the speed-sensorless vector control system of a three-phase induction motor using sliding mode flux/speed observer. The sliding mode observer estimates the rotor speed. The error between the actual and observed currents converges to zero which guarantees the accuracy of the flux observer. The convergence of nonlinear time-varying observer along with the asymptotic stability of the controller was analyzed. To define the control action which maintains the motion on the sliding manifold, an "equivalent control" concept was used. It was simulated and implemented on a sensorless indirect vector drive for 750[W] three-phase induction motor. The simulation and experimental results demonstrated the effectiveness of the proposed estimation method.

• 대한전기학회논문지
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• 제45권2호
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• pp.193-198
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• 1996

Low power superconducting persistent current switch(PCS) for the superconducting magnet systems in the persistent mode was developed and its experimental results were analyzed when the system was charged or discharged. The multifilament NbTi wire with Cu matrix was used for the PCS. The constructed NbTi superconducting switch with superconducting magnet system operated successfully. It also operated on-off switching action with good stabilization. The maximum operating current in persistent mode was 60A (at 1T). In persistent current mode, the decay of the persistent current at 60A was observed. Its decay was 3.55% in 60 min. It is possible to make the persistent current switch with the better decaying of persistent current if some problems for joint resistance are solved.

• The Korean Journal of Physiology and Pharmacology
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• 제11권1호
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• pp.15-20
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• 2007

To investigate whether hydrogen peroxide($H_2O_2$) affects intestinal motility, pacemaker currents and membrane potential were recorded in cultured interstitial cells of Cajal(ICC) from murine small intestine by using a whole-cell patch clamp. In whole cell patch technique at $30^{\circ}C$, ICC generated spontaneous pacemaker potential under current clamp mode(I=0) and inward currents(pacemaker currents) under voltage clamp mode at a holding potential of -70 mV. When ICC were treated with $H_2O_2$ in ICC, $H_2O_2$ hyperpolarized the membrane potential under currents clamp mode and decreased both the frequency and amplitude of pacemaker currents and increased the resting currents in outward direction under voltage clamp mode. Also, $H_2O_2$ inhibited the pacemaker currents in a dose-dependent manner. Because the properties of $H_2O_2$ action on pacemaker currents were same as the effects of pinacidil(ATP-sensitive $K^+$ channels opener), we tested the effects of glibenclamide(ATP-sensitive $K^+$ channels blocker) on $H_2O_2$ action in ICC, and found that the effects of $H_2O_2$ on pacemaker currents were blocked by co- or pre- treatment of glibenclamide. These results suggest that $H_2O_2$ inhibits pacemaker currents of ICC by activating ATP-sensitive $K^+$ channels.

• 약학회지
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• 제29권3호
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• pp.130-143
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• 1985

Bumetanide, when given intravenously in dogs, induced a potent diuresis with an increased amounts of sodium and potassium excreted in urine due to inhibition of reabsorbing them in renal tubule. Furthermore, clearances of osmolar substance and para-aminohippuric acid were increased, but clearace of free water diminished without any change of creatinine clearance. Bumetanide, administered directly into a renal artery, elicited diuresis only in the infused(experimental) kidney by the same mode of action as in the intravenous cases in renal function of the dog. Renal effects of intravenous bumetanide after pretreatment with the small dose of indomethacin (5.0mg/kg) revealed reduction only in clearance of paraaminohippuric acid. However the much dose of indomethacin (5.0mg/kg+5.0mg/kg/hr) or arachidonic acid showed a significant inhibition in the change rates of all renal function by bumetanide. Morover, pretreatment of probenecid also made a marked reduction in renal effects induced by bumetanide. From the above results, it is thought that bumetanide causes diuretic action due to dual mechanism inhibiting reabsorption of electrolytes in loop of Henle and increasing blood flow in kindney, that are provoked through the mediation of prostaglandins.

• Journal of Microbiology and Biotechnology
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• 제25권6호
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• pp.759-764
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• 2015

Antimicrobial peptides (AMPs) are one of the critical components in host innate immune responses to imbalanced and invading microbial pathogens. Although the antimicrobial activity and mechanism of action have been thoroughly investigated for decades, the exact biological properties of AMPs are still elusive. Most AMPs generally exert the antimicrobial effect by targeting the microbial membrane, such as barrel stave, toroidal, and carpet mechanisms. Thus, the mode of action in model membranes and the discrimination of AMPs to discrepant lipid compositions between mammalian cells and microbial pathogens (cell selectivity) have been studied intensively. However, the latest reports suggest that not only AMPs recently isolated but also well-known membrane-disruptive AMPs play a role in intracellular killing, such as apoptosis induction. In this mini-review, we will review some representative AMPs and their antimicrobial mechanisms and provide new insights into the dual mechanism of AMPs.

• 품질경영학회지
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• 제47권3호
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• pp.571-582
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• 2019

Purpose: To develop a risk metric for failure cause that can help determine the action priority of each failure cause in FMEA considering time sequence of cause- failure- detection. Methods: Assuming a quadratic loss function the unfulfilled mission period, a risk metric is obtained by deriving the failure time distribution. Results: The proposed risk metric has some reasonable properties for evaluating risk accompanied with a failure cause. Conclusion: The study may be applied to determining action priorities among all the failure causes in the FMEA sheet, requiring further studies for general situation of failure process.

• 한국잡초학회지
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• 제5권1호
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• pp.7-8
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• 1985