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The Relationship between Serum Ferritin Concentrations, Smoking and Lung Function in Korean (한국인에서 혈청 페리틴 농도와 흡연 및 폐기능과의 관계)

  • Kim, Seo-Yun;Lee, Su-Hwan;Lee, In-Seon;Kim, Sae-Byol;Moon, Chan-Soo;Jung, Sung-Mo;Kim, Se-Kyu;Kim, Young-Sam
    • Tuberculosis and Respiratory Diseases
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    • v.72 no.2
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    • pp.163-168
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    • 2012
  • Background: Cigarette smoke induced release of iron could alter iron metabolism in the lungs of chronic smokers and contribute to the increase in the total oxidative burden on the lungs of smokers. In previous studies, ferritin levels of bronchoalveolar lavage fluid in smokers were elevated. The aim of the present study was to investigate the relationship between serum ferritin concentration, smoking and lung function in Korean people. Methods: This study was based on the data acquired in the second year (2008) of the Forth National Health and Nutrition Examination Survey that was conducted from 2007 to 2009. The analysis included 2,244 subjects who were older than 20 years and had complete data from both lung function test and serum ferritin concentration. Among participants, 1,076 were male and 1,168 were female. Results: Mean serum ferritin concentrations in males were $120.3{\pm}80.1{\mu}g/L$ and $47.9{\pm}39.8{\mu}g/L$ in females. There were no differences in serum ferritin concentrations between non-smokers and smokers after adjusting for age, body mass index, and amounts of alcohol. Serum ferritin concentrations were associated with smoking amounts by simple linear regression but not associated with smoking amounts after adjustment with age, body mass index, and amounts of alcohol in both males and females. Lung function was not associated with serum ferritin concentrations. Conclusion: Our data suggested that serum ferritin concentrations are not related with smoking and lung function.

AN EXPLORATORY STUDY COMPARING BLOOD METAL CONCENTRATIONS BETWEEN STROKE AND NON-STROKE PATIENTS IN KOREANS

  • Lee, Sun-Dong;Ko, Seong-Gyu;Kim, Rok-Ho;Hu, Howard;Amarasiriwardena, Chitra J.;Park, Hae-Mo
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2005.12a
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    • pp.87-94
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    • 2005
  • Results from previous studies revealed that metal level in the body is related to certain types of diseases. For example. serum copper level with chronic heart failure, iron and transferrin in the blood serum with acute cerebral vascular diseases, Zn in the CNS, lead with neurotoxicity, hypertension, genetic damage, arsenic with cancer skin lesion, Al with neurobehavioral function (cognitive impairment and memory disorder), and etc. The rate of stroke has increased in recent years and several metals were found to be responsible for causing stroke. This study compared several blood metal concentrations between stroke and non-stroke patients. Patients with stroke (116 samples) and non-stroke (111 samples including lowback pain and others) participated in this study. Total of 227 blood samples were collected and participants completed questionnaires regarding age, gender, occupation, residence, alcohol, smoking, and etc. To be qualified into the stroke group, patients have never experienced stroke previously. Subjects only included ischemic stroke and intracerebral hemorrhage patients diagnosed by brain CT and brain MRI. Patients with high risk of metal exposure such as herbal intake and job related exposure were excluded. 10ml of blood samples were analyzed by ICP-MS method at the Center of Nature and Science at Sangji University. Metal geometric mean (SD) concentrations in blood of study subjects showed higher values, 2.64-36.12%, than WHO reference values in Mn, Ni, Hg, Se, and As. Metal concentration in blood of stroke patients non-adjusted for potential confounders was higher except for Hg and also higher except for Ni in adjusted for potential confounders. Co was significantly higher in stroke patients (p=0.002) than non-stroke patients adjusted for potential confounders. Regression coefficient values of stroke patients was 0.17-8.25 in each metals. Odd ratio of stroke patients had 0.96 (Ni)-2.68 (Co) compared to non-stroke cases. This result means that Co increase of 1 raises the risk ratio of stroke by 2.86 times. Based on the results, metal concentration in blood seems to affect incidence of stroke.

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Development and its Application for Energy Efficiency Operation Indicator and Energy Efficiency Design Index Monitoring System on the Ship (선박의 에너지효율운전지표와 에너지효율설계지수의 모니터링 시스템 개발과 그 응용)

  • Lee, Don-Chool;Kim, Eoue-Sek;Joo, Ki-Se;Nam, Jeong-Gil
    • Journal of Advanced Marine Engineering and Technology
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    • v.34 no.4
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    • pp.500-507
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    • 2010
  • Regard to the global warming, the shipping industries are progressed the dedicated endeavor to reduce greenhouse gas. As the study results of 2009 GHG study team, the $CO_2$ emission of shipping industries exceeded slightly 1.0 billion ton during one year(2007) and it is 3.3% of total $CO_2$ amount exhausted from all industries. This paper are introduced the energy efficiency design index / operation indicator monitoring system(EDiMS) which matched with EVAMOS software released by the dynamics laboratory of Mokpo maritime university. EDiMS can continuously be monitored amounts of $CO_2$, NOx, SOx, and PM emitted from ship and it can be applied as the useful tool of the inventory work of air pollution and the ship energy management plan for the mitigation or reduction of ship emission.

Effects of Cavity Configuration on Bond Strength and Microleakage of Composite Restoration (와동의 형태에 따른 복합레진의 결합강도 및 변연누출에 관한 연구)

  • Choi, Seung-Mo;Choi, Gi-Woon;Choi, Kyoung-Kyu;Park, Sang-Jin
    • Restorative Dentistry and Endodontics
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    • v.27 no.5
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    • pp.479-487
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    • 2002
  • 복합레진의 중합시 발생하는 수축과 응력은 와동의 형태에 의하여 영향을 받으며 이는 수복재는 물론 접착계면의 물성을 결정하는 요인이 된다. 본 연구는 다양한 C-factor를 갖는 와동에 상아질 접착제 Clearfil SE Bond(Kuraray)를 도포하고 혼합형 복합레진인 Clearfil AP-X(Kuraray)와 미세혼합형의 Esthet-X(Dentsply)를 충전하여 미세인장강도 및 변연누출을 측정 평가함으로써 중합수축이 수복물과 치아계면에 미치는 영향을 평가하고자 시행하였다. 98개의 Bovine 하악전치를 이용하여 표면의 상아질을 #600 SiC paper로 연마한 대조군 및 와동의 넓이를 조절하여 C-factor 2.3, 3.0, 3.7이 되도록 제작한 실험군 와동에 복합레진을 충전한 후 37의 증류수에 24시간 보관하였다. 저속 diamond saw(Buehler)를 이용하여 1mm 두께로 수직절단 후 고속 diamond point(#104 Shofu)를 이용하여 단면적 1mm$^2$가 되도록 hour-glass모양으로 형성하여 시편을 제작하였고, Universal testing machine(EZ-Test; Shimadzu, Japan)에 시편을 부착하고 cross head speed 1mm/min으로 인장력을 가하여 미세인장 결합강도를 측정하였다. 각 C-factor에 따른 변연누출실험을 위하여 복합레진이 수복된 치아를 37$^{\circ}C$의 증류수에 24시간 보관한 후 와동을 제외한 부위에 nail varnish를 도포하고 3mol/L silver nitrate용액에 24시간 암보관한 다음 수세하여 현상액에 24시간 경과시킨 후 치아의 장축에 따라 절단하여 침투된 색소의 정도를 광학현미경상에서 40배로 관찰하였다. 각각의 실험결과는 ANOVA/Tukey's test 및 Kruskal-Wallis non-parametric independent analysis와 Mann-Whitney U test에 의하여 통계 분석하여 다음과 같은 결론을 얻었다. 1. 대조군에 있어서 혼합형 복합레진의 미세인장 결합강도는 미세혼합형에 비하여 높았으며, 실험군 사이에는 유의차를 보이지 않았다. 2.모든 복합레진의 미세인장 결합강도는 와동의 C-factor증가에 따라 감소하는 경향을 나타내었고, 혼합형 복합레진의 실험군은 대조군에 비하여 낮게 나타났으며, 미세혼합형 복합레진에서는 유의차를 보이지 않았다. 3. 절단측 및 치은측 변연부의 미세누출정도는 혼합형 복합레진이 미세혼합형에 비하여 대체로 높게 나타났다. 4. 모든 실험군에서 미세누출은 C-factor증가에 따라 증가하였고 절단측에 비하여 치은측 변연이 높게 나타났으나 통계학적 유의차는 보이지 않았다. C-factor의 변화에 대하여 필러함량과 탄성계수가 높은 혼합형 복합레진이 미세혼합형에 비하여 더 민감한 결과를 보인다. 이는 복합레진 수복시 재료의 선택과 중합수축의 적절한 조절이 중요한 요소임을 시사한다.

Incidence of micronuclei in lymphocytes of pig in the high background radiation area (Cheongwon-gun and Boeun-gun) (국내 자연 방사선 고준위 지역(청원군, 보은군) 사육 돼지의 림프구 미소핵 발생 평가)

  • Lee, Hae-June;Kang, Chang-Mo;Kim, Se-Ra;Lee, Jin-Hee;Kim, Joong-Sun;Kim, Jong-Choon;Kim, Ill-Hwa;Kim, Tae-Hwan;Ryu, Si-Yun;Jo, Sung-Kee;Choi, Soo-Yong;Kim, Sung-Ho
    • Korean Journal of Veterinary Research
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    • v.45 no.4
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    • pp.469-475
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    • 2005
  • Cytogenetic and hematological analysis was performed in peripheral blood obtained from pigs bred in the high background radiation areas (HBRA) (Cheongwon-gun and Boeun-gun) and a control area. The frequencies of gamma-ray induced micronuclei (MN) in the cytokinesis-blocked (CB) lymphocytes at several doses were measured in three pigs. An estimated dose of radiation was calculated by a best fitting linear-quadratic model based on the radiation-induced MN formation from the swine lymphocytes exposed in vitro to radiation over the range from 0 mGy to 1,969 mGy. The measurements performed after irradiation showed dose-related increases in the MN frequency in each donors. The results were analyzed using a linear-quadratic model with a line of best fit of $y=0.0005404D^2+0.04237D+0.00833$ [y = number of MN/cytokinesis-blocked (CB) cells and D = irradiation dose in Gy]. MN rates per 1,000 CB lymphocytes of pig from the HBRA (Cheongwon-gun, Boeun-gun) and the control area were $6.70{\pm}2.36$, $9.00{\pm}3.50$ and $11.00{\pm}2.98$, respectively. The MN frequencies of CB lymphocytes from pigs bred in three areas means that the values are within the background variation in this experiment. The MN frequencies and hematological values were similar regardless of whether the pigs were bred in the HBRA or the control area.

A Study on the Test Results and Wideband Observing of the Korean VLBI Network (KVN의 광대역 관측 시험 및 결과고찰)

  • Oh, Se-Jin;Oyama, Tomoaki;Yeom, Jae-Hwan;Nishikawa, Takashi;Roh, Duk-Gyoo;Kim, Seung-Rae;Lee, Eui-Gyeom;Je, Do-Heung;Byun, Do-Young;Lee, Seong-Mo;Chung, Hyun-Soo
    • Journal of the Institute of Convergence Signal Processing
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    • v.17 no.2
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    • pp.83-92
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    • 2016
  • In this paper, we introduce the results of the testing and observation systems for performance wideband expansion in the Korean VLBI Network(KVN). The KVN performs VLBI observations to 1024 Mbps data rate, and 8192 Mbps observing for four simultaneous observation is now evaluating for normal operation. The VLBI stations in several world countries developed their own wideband observing systems to observe the celestial objects with high precision and high resolution or are working with several countries. The KVN is planning to introduce a high-speed sampler, OCTAD, for sampling directly up to 2048 MHz bandwidth for RF signal of K/Q/W/D band in the frequency band without conversion. Therefore, as a preliminary study for the performance scalability of the KVN then through the close cooperation with National Astronomical Observatory of Japan (NAOJ), the OCTAD high-speed sampler and OCTADISK2 high-speed recorder were installed in the KVN Yonsei station, and verify the performance through a wideband.

Effect of surface treatment of FRC-Post on bonding strength to resin cements (FRC-포스트의 표면처리가 레진시멘트와의 접착력에 미치는 영향)

  • Park, Chan-Hyun;Park, Se-Hee;Kim, Jin-Woo;Cho, Kyung-Mo
    • Restorative Dentistry and Endodontics
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    • v.36 no.2
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    • pp.125-131
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    • 2011
  • Objectives: The purpose of this study was to evaluate the effect of surface treatment of FRC-Post on bonding strength to resin cements. Materials and Methods: Pre-surface treated LuxaPost (DMG), Rely-X Fiber Post (3M ESPE) and self adhesive resin cement Rely-X Unicem (3M ESPE), conventional resin cement Rely-X ARC (3M ESPE), and Rely-X Ceramic Primer (3M ESPE) were used. After completing the surface treatments of the posts, posts and resin cement were placed in clear molds and photo-activation was performed. The specimens were sectioned perpendicular to the FRC-Post into 2 mm-thick segments, and push-out strength were measured. The results of bond strength value were statistically analyzed using independent samples t-test and oneway ANOVA with multiple comparisons using Scheffe's test. Results: Silanization of posts affect to the bond strength in LuxaPost, and did not affect in Rely-X Fiber Post. Rely-X ARC showed higher value than Rely-X Unicem. Conclusions: Silanization is needed to enhance the bond strength between LuxaPost and resin cements.

Effect of curing modes on micro-hardness of dual-cure resin cements (중합방법이 이중중합 레진시멘트의 미세경도에 미치는 영향)

  • Lee, Ki-Deok;Park, Se-Hee;Kim, Jin-Woo;Cho, Kyung-Mo
    • Restorative Dentistry and Endodontics
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    • v.36 no.2
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    • pp.132-138
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    • 2011
  • Objectives: The purpose of this study was to evaluate curing degree of three dual-cure resin cements with the elapsed time in self-cure and dual-cure mode by means of the repeated measure of micro-hardness. Materials and Methods: Two dual-cure self-adhesive resin cements studied were Maxcem Elite (Kerr), Rely-X Unicem (3M ESPE) and one conventional dual-cure resin cement was Rely-X ARC resin cement (3M ESPE). Twenty specimens for each cements were made in Teflon mould and divided equally by self-cure and dual-cure mode and left in dark, $36^{\circ}C$, 100% relative humidity conditional-micro-hardness was measured at 10 min, 30 min, 1 hr, 3 hr, 6 hr, 12 hr and 24 hr after baseline. The results of micro-hardness value were statistically analyzed using independent samples t-test and one-way ANOVA with multiple comparisons using Scheffe's test. Results: The micro-hardness values were increased with time in every test groups. Dual-cure mode obtained higher micro-hardness value than self-cure mode except after one hour of Maxcem. Self-cured Rely-X Unicem showed lowest value and dual-cured Rely-X Unicem showed highest value in every measuring time. Conclusions: Sufficient light curing to dual-cure resin cements should provided for achieve maximum curing.

Quality Change of Packaged Pears in PLA Tray for Export due to Vibration Stress by Simulated Transport Environment (PLA 트레이 포장 수출용 배의 수송 모의환경 진동 스트레스에 의한 품질변화)

  • Choi, Dong-Soo;Son, Jae-Yong;Kim, Jin-Se;Kim, Yong-Hoon;Park, Chun-Wan;Hwang, Sung-Wook;Park, Jong-Min;Jung, Hyun-Mo
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.27 no.2
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    • pp.109-114
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    • 2021
  • The characteristics of vibrational stress (shock and vibration) during transport and the possibility of damage to the packaged pears by functional PLA tray were investigated. And this study was conducted to analyze how environmental conditions by simulated transport environment affect quality factors such as weight loss (%) and soluble solid content (SSC, %), and firmness (bioyield strength, kPa) of packaged pears by PLA tray and Expanded PET foam pad (Group 1), EPE cushion cup pad and net (Group 2) for exporting. Pears with or without vibration stress were stored for 30 days at low temperatures (5 ± 0.8℃, 80 ± 5% relative humidity). There was the statistically significant difference (p ≤ 0.05) between pears with and without vibration stress for weight loss, soluble solid content, and firmness (bioyield strength) after 30 days storage. Vibration stress accelerated pear quality deterioration during storage, resulting in increased weight loss, soluble solids content, and reduced hardness. The firmness (bioyield strength) and weight changes of pears with PLA trays were smaller than those of conventional packaging box systems. It was determined that the firmness of agricultural products was a quality factor closely related to the storage period and that PLA could be applied.

A study on Radix Entomolaris about prevalence and correlation of canal orifices location according to number of roots in mandibular first molars (하악 제1대구치에서 Radix Entomolaris의 발현빈도와 치근의 개수에 따른 근관 입구들 사이의 위치 관계에 대한 연구)

  • Jang, Ji-Hye;Kim, Jin-Woo;Cho, Kyung-Mo;Kim, Soo-Yeon;Park, Se-Hee
    • The Journal of the Korean dental association
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    • v.56 no.12
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    • pp.695-706
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    • 2018
  • Objectives: The purpose of this study was to investigate the ratio of 4 root canals and the incidence of Radix Entomolaris in mandibular first molars and find out anatomical difference according to number of roots by analysis of cone-beam CT images in a Korean population. Materials and Methods: Total 142 images containing mandibular first molars were selected from CBCT images taken from 2013 to 2017 at Gangneung-Wonju National University Dental Hospital. After reconstructing the image with reference to the Cemento-enamel junction, the root canals were detected at the bottom of the pulpal floor and the number of roots and root canals were analyzed. Various lengths and MLO-DLO-DBO angle were measured between each canal orifices and the external contour line of the tooth, and the distolingual canal wall thickness was measured. Student t-test was used for statistical significance. Results: Among the total 142 teeth, 4 canals were 42.2% and Radix Entomolaris was 25.3%. As the results of measuring various lengths and the angle, the distolingual canal orifice in Group 2(with Radix Entomolaris) tends to deviate to the lingual side than the mesiolingual canal orifice and to the mesial side than the distobuccal canal orifice. Besides, thickness of the distolingual canal wall in Group 2(with Radix Entomolaris) was significantly thinner than that of Group 1 at every level except pulpal floor level. Conclusion: It is necessary to consider the difference according to the presence of Radix Entomolaris in endodontic treatment.

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