• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 2002년도 제9회 학술 발표회 프로그램과 논문초록
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• pp.56-56
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• 2002

Muscle contraction and relaxation are regulated by the sarcoplasmic reticulum (SR)-mediated $Ca^{2＋}$ release and $Ca^{2＋}$ uptake. The SR functions are closely related with the proteins residing in the SR such as ryanodine receptor, $Ca^{2＋}$-ATpase, calsequestrin, triadin and junctin. In an effort to further identify important functional SR proteins, experiments of sucrose-density gradient of SR fractionation, concanavalin A treatment, 2D gel electrophoresis, $^{45}$ Ca$^{2+}$ overlay, Strains-all staining, and peptide finger printing (PFP) were carried out.(omitted)d)

• 대한통합의학회지
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• 제10권4호
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• pp.83-91
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• 2022

Purpose: The goal of this study was to investigate changes in dual-task performance according to age and difficulty of cognitive tasks for the in community-dwelling elderly populations, as well as to examine their changes in hand dexterity according to age and cognitive function. Methods: A total of 135 people aged 65 years old and over participated in the study. To evaluate each participant's dual-task performance, each participant completed a dual task. To assess their cognitive function, the Korean Mini-Mental State Examination (MMSE-K) and the Korean version of Montreal Cognitive Assessment (MoCA-K) were the tools used. Participants were divided into three groups based on their age: 65-69 years, 70-79 years, and 80-89 years. Results: The findings showed that age groups and the difficulty of the cognitive task significantly affected the amount of time required for dual-task performance (p<.001). Additionally, the dual-task correct response rate (CRR) decreased significantly with age groups and the difficulty of the cognitive task (p<.001). The amount of time required for finger dexterity performance increased significantly with age groups (mean score±standard deviation [SD]; 19.46±2.26 in subjects aged 65-69 years; 21.92±2.61 in subjects aged 70-79 years; and 23.82±2.92 in subjects aged 80-89 years; p<.001). Moreover, as a result of the correlation between hand dexterity and cognitive function, MoCA-K was -0.563 and MMSE-K was -.412, showing a statistically significant correlation (p<.001). Conclusions: Age and the difficulty of the cognitive task affect the community-dwelling elderly populations in terms of dual-task performance and dual-task CRR. In addition, aging and general cognition have an impact on hand dexterity. Based on the results of this study, it is anticipated that the results will serve as a reference for domestic clinical trials that confirm cognitive decline in the elderly using dual task and hand dexterity evaluation.

• 한국융합학회논문지
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• 제10권9호
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• pp.85-90
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• 2019

본 연구는 65세 이상 경도인지장애 7명을 대상으로 개별 보드게임프로그램 및 추척관찰을 통하여 인지기능 및 우울 수준에 미치는 영향을 알아보고자 하였고 이를 위해 Mini-Mental State Examination Korean version(MMSE-K), Korean Version of Montreal Cognitive Assessment(MoCA-K) 및 Korean Gorm of Geriatric Depression Scale(KGDS)를 사용하였다. 연구결과, MMSE-K 중재 전, 후 및 추적평가에서 유의한 차이를 보였고(p<0.05) 세부항목 중 시간, 장소 및 물건 인식력과 집중력에서 차이를 보였다(p<0.05). MoCA-K는 중재 전, 후 및 추적평가에서 차이를 보였는데(p<0.01) 세부항목 중 시공간, 이름 인식력, 주의집중 및 단기기억력에서 차이를 보였다(p<0.05). KGDS을 통한 우울수준의 중재 전, 후 및 추적 비교에서 우울에 차이를 보였다(p<0.01). 따라서 65세 이상의 경도인지장애 고령자의 개별보드게임은 인지기능을 개선에 도움을 줄 수 있고 또한 고령자의 시간과 장소 인식력을 포함된 개선된 보드게임이 개발되고 적용되기 기대한다.

• 한국산학기술학회논문지
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• 제19권12호
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• pp.758-764
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• 2018

본 연구는 작업 중심 회상치료가 경도 치매 노인 환자의 인지기능과 우울 그리고 그들의 삶의 질에 미치는 영향을 알아보고자 실시되었다. 경도 치매 노인 환자 31명을 대상으로, 총 8주 동안 주 1회, 각 회기 당 40분의 작업 중심 회상치료를 실시하였다. 평가도구는 대상자의 인지기능 평가를 위해서 한국형 몬트리올 인지평가(Montreal Cognitive Assessment Korean Version:MoCA-K), 우울정도 측정을 위해 단축형 한국판 노인우울척도검사(Short Form of Geriatric Depression Scale-Korean Version:SGDS-K), 그리고 대상자들의 삶의 질 측정을 위해 치매노인 대상 삶의 질 척도(Geriatric Quality of Life-Dementia:GQOL-D)를 사용하였다. 연구결과 작업 중심 회상치료 실시 전에 비하여 경도 치매 노인 환자의 MoCA-K 점수는 중재 전 $14.62{\pm}5.07$에서 중재 후 $16.88{\pm}4.55$로, SGDS-K 점수는 중재 전 $7.28{\pm}4.28$에서 중재 후 $6.10{\pm}4.09$로, 마지막으로 GQOL-D 점수는 중재 전 $26.05{\pm}5.45$에서 중재 후 $28.55{\pm}5.74$로 변화하여 측정된 모든 항목에서 통계적으로 유의미한 긍정적 변화를 확인할 수 있었다. 본 연구 결과를 토대로 작업 중심 회상훈련이 경도 치매 노인 환자들의 인지기능, 우울 그리고 삶의 질에 긍정적 영향을 미칠 수 있다는 가능성을 확인할 수 있었다.

• 한국결정성장학회지
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• 제8권3호
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• pp.383-387
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• 1998

대구경(직경 4inch이상) $CaF_2$ 단결정성장을 위하여 vacuum-Bridgman 장치를 구성하였으며, 성장속도 2mm/hr, 성장온도구배 $12^{\circ}C$/cm의 조건하에서 성장한 $CaF_2$ 단결정은 우수한 물성을 갖는 것으로 분석되었다. 우산형(umbrella shape)의 Mo thermal reflector를 사용한 경우에 polycrystalline으로의 성장을 제거할 수 있었다. 성장우선방위는 (111)면이었으며, 분말 XRD법에 의한 peak로부터 $5.460\AA$의 격자상수를 구하였다. 또한 XRD분석에 의하면 제2상은 형성되지 않았으며, EPD값은 $1.4{\times}10^4 \textrm{cm}^{-2}$이었다. 성장된 결정은 UV영역의 광학부품용도로 사용하기에 적합한 투과율 91%이상의 특성을 나타내었다.

• The Journal of Korean Physical Therapy
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• 제13권1호
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• pp.237-243
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• 2001

Skeletal muscle cells are activated by ${\alpha}$-motorneurons which release acetylcholine at the neuromuscular junction. This results in a local depolarization of surface membrane which triggers an action potential. The action potential propagates along the surface membrane and also into the T-tubule system. In the triads T-tubules are in close connection with the terminal cisternae of the sarcoplasmic reticulum(SR). The action potential activaies T-tubule voltage sensors(DHP receptors). which activates SR Ca$^{2+}$ release channels(ryanodinc receptors). Ca$^{2+}$ have a key role in skeletal muscle in that an increase of free myoplasmic Ca$^{2+}$ concentration. The process of coupling chemical and electrical signals at the cell surface to the intracellular release of Ca$^{2+}$and ultimate contraction of muscle fibers is termed excitation-contraction coupling(ECC). Coupling of cel1 surface signals to intracellular Ca$^{2+}$ release proceeds by several mechanisms in skeletal muscle cells. This review focus on sarcopiasmic reticulum(SR) Ca$^{2+}$ releasing mechanisms from sarcoplasmic reticulum in the skeletal muscle. The mechanisms include DCCR, CICR, and HCR.

• 대한화학회지
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• 제53권3호
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• pp.272-278
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• 2009

$Ca^+-(CO)_n$,과 $Ca^+-(CO_2)_n$ (n=1,2) complex에 대한 구조와 결합 에너지를 MP2/6-311++G(2d,p) 방 법과 B3LYP/6-311++G(2d,p) 방법에 의해 계산하였고 vibrational frequencies도 계산하였다. $Ca^+-(CO)_n$의 경우 C-bonded complex와 O-bonded complex가 다 가능함을 보였고, $Ca^+-(CO)_2$에서는 선형과 $C_{2v}$ 형태가 나타남을 볼 수 있었으며 더 안정한 형태는 $C_{2v}$ 구조로 밝혀졌다. $Ca^+-(CO_2)_2$에서도 선형과 $C_{2v}$ 형태를 볼 수 있는데 이 경우는 선형이 근소한 에너지 차이로 더 안정한 것으로 나타났다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1999년도 춘계학술대회 논문집
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• pp.295-299
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• 1999

The (S $r_{1-x}$C $a_{x}$)Ti $O_3$(SCT) thin films are deposited on Pt-coated electrode(Pt/TiN/ $SiO_2$/ Si) using RF sputtering method with substitutional contents of Ca. The maximum grain of thin films is obtained by substitution of Ca at 15[mol%]. The dielectric constant was increased with increasing the substitutional contents of Ca, while it was decreased if the substitutional contents of Ca exceeded over 15[mo1%]. The dielectric constant changes almost linearly in temperature ranges of -80~ +90[$^{\circ}C$]. The temperature properties of the dielectric loss have a stable value within 0.02 independent of the substitutional contents of Ca. All SCT thin films used in this study show the phenomena of dielectric relaxation with the increase of frequency, and the relaxation frequency is observed above 200(kHz).)..

• Environmental Engineering Research
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• 제21권3호
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• pp.247-255
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• 2016

Ten trace elements (Mg, Ca, V, Cr, Mn, Fe, Cu, Zn, Mo, and Cd) were determined in seven traditionally used wild medicinal plants of the Nagas in the North-East India viz Cynoglossum furcatum Wallich, Elsholtzia blanda Bentham, Lycopodium cernuum Linnaeus, Potentilla fulgens Wallich ex Hooker, Swertia macrosperma C.B. Clarke, Thalictrum foliolosum DC and Valeriana jatamansi Jones. Plant samples were dried, weighed, digested and analyzed for their mineral distribution level ranging from trace to major elements by graphite furnace-atomic absorption spectroscopy. All the medicinal herbs studied were found to contain the ten elements analyzed. The elemental concentration is given in mg/kg. Mg and Ca are present in high concentrations in both the roots and leaves of the plant samples. Among trace transition metals Fe had the highest concentration, followed by Mn, Cr, Cu, V, Zn, and Mo. Analysis showed that the toxic Cd element was at a lower concentration and is within the permissible limit of FAO/WHO, California standards and United States Pharmacopeia Limit for Nutritional Supplements.

• 자원환경지질
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• 제25권3호
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• pp.245-258
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• 1992

The variations of certain major and trace elements of the Onjong granite mass was studied on the basis of petrological and geochemical characteristics and compared with those of the Eonyang-Yucheon granite masses in order to investigate the geochemical differences of the granitic rocks in relation to mineralization between Pb-Zn ore district and Pb-Zn-Mo-W ore district in Kyeongsang basin. The Onjong granite mass is classified into granodiorite and monzo-granite, and the Eonyang-Yucheon granite masses into monzo-granite by the Streckeisen's diagram. Between both granite masses there are clear differences in contents of certain major elements and lithophile trace elements. The former have high contents of Ca (2.94%), Mg (1.66%) and Sr (365 ppm), and low contents of K (3.52%), Na (3.51%), Rb (116 ppm), Ba (640 ppm) and Li (18.9 ppm), whereas the latter have high contents of K (4.02%), Na (4.28%), Rb (145 ppm), Ba (695 ppm) and Li (19.3 ppm), and low contents of Ca (1.42%), Mg (0.43%) and Sr (161 ppm). Except for Mo, there are not clear differences in chalcophile trace elements between two granite masses: the Onjong granite mass has higher Mo content (7.1 ppm) lnan that (1.7 ppm) of the Eonyang-Yucheon granite masses, but Pb and Zn contents are similar between the Onjong granite mass (Pb=8.7 ppm, Zn=37.1 ppm) and the Eonyang-Yucheon granite masses (Pb=7.8 ppm, Zn=39.8 ppm). Ca and Sr contents of the Onjong granite mass (Ca> 1.5%, Sr> 270 ppm) are higher than those of the Eonyang- Yucheon granite masses (Ca<1.5%, Sr<270ppm), and Rb/Sr, Rb-Rb/Sr and K-Rb/Sr ratios are clearly distinguishable between the Onjong granite mass(Rb/Sr<0.51, Rb-Rb/Sr>250 and K-Rb/Sr>5.2) and the Eonyang- Yucheon granite masses (Rb/Sr>0.51, Rb-Rb/Sr<250 and K-Rb/Sr<5.0). Thus, variations of certain major and trace elements and ratios are applicable as geochemical index to distinguish the types of mineralization of the ore districts related to the Cretaceous granitic rocks in the Kyeongsang basin.