• International Journal of Fluid Machinery and Systems
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• v.10 no.2
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• pp.138-145
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• 2017

The problem of non-uniform inflow exists in many practical engineering applications, such as the elbow suction pipe of waterjet pump and, the channel head of steam generator which is directly connect with reactor coolant pump. Generally, pumps are identical designs and are selected based on performance under uniform inflow with the straight pipe, but actually non-uniform suction flow is induced by upstream equipment. In this paper, CFD approach was employed to analyze unsteady hydrodynamic characteristics of reactor coolant pumps with different inflows. The Reynolds-averaged Naiver-Stokes equations with the $k-{\varepsilon}$ turbulence model were solved by the computational fluid dynamics software CFX to conduct the steady and unsteady numerical simulation. The numerical results of the straight pipe and channel head were validated with experimental data for the heads at different flow coefficients. In the nominal flow rate, the head of the pump with the channel head decreases by 1.19% when compared to the straight pipe. The complicated structure of channel head induces the inlet flow non-uniform. The non-uniformity of the inflow induces the difference of vorticity distribution at the outlet of the pump. The variation law of blade to blade velocity at different flow rate and the difference of blade to blade velocity with different inflow are researched. The effects of non-uniform inflow on radial forces are absolutely different from the uniform inflow. For the radial forces at the frequency $f_R$, the corresponding amplitude of channel head are higher than the straight pipe at $1.0{\Phi}_d$ and $1.2{\Phi}_d$ flow rates, and the corresponding amplitude of channel head are lower than the straight pipe at $0.8{\Phi}_d$ flow rates.

• Environmental Analysis Health and Toxicology
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• v.21 no.2 s.53
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• pp.127-138
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• 2006

In urban areas, diesel exhaust particles (DEP) are probably a major component of particulate matters, especially in Korea where drive many diesel vehicles. The aim of this study was to investigate genotoxic effects of DEP using single ceil gel electrophoresis. In order to evaluate the mechanisms of DEP genotoxicity, the rat microsome mediated and DNA repair enzyme treated comet assays together with conventional comet assay were performed. Total diesel particles (DEPT) was collected without site fractionation from diesel engine bus and dichloromethane extract was obtained. The organic extract of DEPT revealed DNA damage itself in NIH/3T3 cells. The level of DNA breaks plus oxidative DNA lesions and microsome mediated DNA damage was assessed by modified single cell gel eletrophoresis. DEPT was able to induce oxidative DNA damage as well as microsome mediated DNA damage. Vitamin C as an model antioxidant reduced DNA damage in endonuclase III treated comet assay. One of flavonoid, galangin as a CYP1A1 inhibitor. reduced DNA damage in the presence of S-9 mixture. $DEP_T$ is the sources of oxidative stress, but antioxidants can significantly reduce oxidative DNA dmage. And $DEP_T$ may contain indirect mutagens which can be inhibited by CYP1A1 inhibitors. The ethanol extracts of the mixed vegetables (BV) or the mixed fruits (BF) were evaluated for their in vitro antigenotoxic effects. BV and BF showed potent Inhibitory effects against DEPT induced DNA damage with oxidative DNA lesions and in the prescence of S-9 mixture. These results indicate that BV and BF could prevent cellular DNA damage by inhibiting oxidative stress and suppressing cytochrome P4501A1 in cell culture.

• Earthquakes and Structures
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• v.7 no.4
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• pp.485-510
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• 2014

In performance-based seismic design procedures Peak Ground Acceleration (PGA) and pseudo-Spectral acceleration ($S_a$) are commonly used to predict the response of structures to earthquake. Recently, research has been carried out to evaluate the predictive capability of these standard Intensity Measures (IMs) with respect to different types of structures and Engineering Demand Parameter (EDP) commonly used to measure damage. Efforts have been also spent to propose alternative IMs that are able to improve the results of the response predictions. However, most of these IMs are not usually employed in probabilistic seismic demand analyses because of the lack of reliable Ground Motion Prediction Equations (GMPEs). In order to define seismic hazard and thus to calculate demand hazard curves it is essential, in fact, to establish a GMPE for the earthquake intensity. In the light of this need, new GMPEs are proposed here for the elastic input energy spectra, energy-based intensity measures that have been shown to be good predictors of both structural and non-structural damage for many types of structures. The proposed GMPEs are developed using mixed-effects models by empirical regressions on a large number of strong-motions selected from the NGA database. Parametric analyses are carried out to show the effect of some properties variation, such as fault mechanism, type of soil, earthquake magnitude and distance, on the considered IMs. Results of comparisons between the proposed GMPEs and other from the literature are finally shown.

• Radiation Oncology Journal
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• v.34 no.2
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• pp.135-144
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• 2016

Purpose: The purpose of this study was to evaluate the efficacy of art therapy to control fatigue in cancer patients during course of radiotherapy and its impact on quality of life (QoL). Materials and Methods: Fifty cancer patients receiving radiotherapy received weekly art therapy sessions using famous painting appreciation. Fatigue and QoL were assessed using the Brief Fatigue Inventory (BFI) Scale and the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) at baseline before starting radiotherapy, every week for 4 weeks during radiotherapy, and at the end of radiotherapy. Mean changes of scores over time were analyzed using a generalized linear mixed model. Results: Of the 50 patients, 34 (68%) participated in 4 sessions of art therapy. Generalized linear mixed models testing for the effect of time on mean score changes showed no significant changes in scores from baseline for the BFI and FACIT-F. The mean BFI score and FACIT-F total score changed from 3.1 to 2.7 and from 110.7 to 109.2, respectively. Art therapy based on the appreciation of famous paintings led to increases in self-esteem by increasing self-realization and forming social relationships. Conclusion: Fatigue and QoL in cancer patients with art therapy do not deteriorate during a period of radiotherapy. Despite the single-arm small number of participants and pilot design, this study provides a strong initial demonstration that art therapy of appreciation for famous painting is worthy of further study for fatigue and QoL improvement. Further, it can play an important role in routine practice in cancer patients during radiotherapy.

• Journal of the Korean Recycled Construction Resources Institute
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• v.9 no.4
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• pp.650-657
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• 2021

Alkali activators that stimulate mineral compounds are expensive materials, but in order to replace industrial products of high alkali in gredien ts, both product an d econ omic feasibility must be satisfied. In this study, alkali in dustrial waste(LW) from the LCD man ufacturin g process were used for the purpose of alkali active reaction of GGBFS for high stren gth concrete over 50MPa. Concrete mixed with LW had reduced workability, but it had the characteristic of increasing compressive strength. Analysis using ACI 209 Compressive Strength Model Equation was made to compare the changes in strength coefficients according to LW mixing. The durability test of concrete, such as Chloride Penetration Resistance and carbonation resistance, also showed excellent performance. In the Adiabatic temperature rise test results, the concrete mixed with LW had the effect of accelerating the initial hydration heat. However, the final Adiabatic temperature rise was not significantly affected by the mixing of LW.

• International Area Studies Review
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• v.18 no.3
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• pp.175-201
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• 2014

This paper analyses the effect of R&D investment on local economies. R&D investment contributes to the regional local economy by increasing employment and production activity of the investees. The investees may end up with increased productivity, sales and employment. At the regional R&D level, the central government R&D fund and firm self R&D budget will be the source of R&D investment. Further positive effects are inter-related with local industries. This study carried out an empirical analysis on the effect of R&D investment on local economies using Korean panel data after comparing international literatures. The dynamic panel estimator is used to estimate an autoregressive model with lagged dependent variable. Using the Da Silva method, mixed variance-component moving-average error process is estimated and selected. R&D investment is very important factor to improve the productivity of a region and the size of the effect is dependent on the time periods within the Korean economic history.

• Korean Journal of Radiology
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• v.22 no.10
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• pp.1708-1718
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• 2021

Objective: The purpose of this study was to evaluate the magnetic resonance (MR) characteristics and applicability of new, uniform, extremely small iron-based nanoparticles (ESIONs) with 3-4-nm iron cores using contrast-enhanced magnetic resonance angiography (MRA). Materials and Methods: Seven types of ESIONs were used in phantom and animal experiments with 1.5T, 3T, and 4.7T scanners. The MR characteristics of the ESIONs were evaluated via phantom experiments. With the ESIONs selected by the phantom experiments, animal experiments were performed on eight rabbits. In the animal experiments, the in vivo kinetics and enhancement effect of the ESIONs were evaluated using half-diluted and non-diluted ESIONs. The between-group differences were assessed using a linear mixed model. A commercially available gadolinium-based contrast agent (GBCA) was used as a control. Results: All ESIONs showed a good T1 shortening effect and were applicable for MRA at 1.5T and 3T. The relaxivity ratio of the ESIONs increased with increasing magnetic field strength. In the animal experiments, the ESIONs showed peak signal intensity on the first-pass images and persistent vascular enhancement until 90 minutes. On the 1-week follow-up images, the ESIONs were nearly washed out from the vascular structures and organs. The peak signal intensity on the first-pass images showed no significant difference between the non-diluted ESIONs with 3-mm iron cores and GBCA (p = 1.000). On the 10-minutes post-contrast images, the non-diluted ESIONs showed a significantly higher signal intensity than did the GBCA (p < 0.001). Conclusion: In the phantom experiments, the ESIONs with 3-4-nm iron oxide cores showed a good T1 shortening effect at 1.5T and 3T. In the animal experiments, the ESIONs with 3-nm iron cores showed comparable enhancement on the first-pass images and superior enhancement effect on the delayed images compared to the commercially available GBCA at 3T.

• Science of Emotion and Sensibility
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• v.21 no.3
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• pp.3-16
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• 2018

Despite the substantial changes made in the product design field to adopt light as an essential design element, there has been little effort to define how customers respond emotionally to the light design of products. Therefore, it is necessary to analyze the emotional effect of light as a new design element. However, previous research focuses solely on deriving optimal lighting conditions to achieve particular emotional effects. Therefore, this paper investigates the customers' desired emotional effects of product's light design. We studied refrigerators that utilize light as the main design element of the product. We applied mixed methods by combining close-ended questions and open-ended question to efficiently derive the desired emotion. Participants were asked to choose the most favorable refrigerator image in each of the twelve image groups and indicate why they choose that image with the short-answer survey form. Approximately one thousand terms were collected, and those terms were classified into 29 groups using thesaurus relationships. The term groups were again classified into the four big emotion categories and labelled as "abstract quality," "light property," "space perception," and "visual comfort." Also, a model of the relationship between desired light style and light properties was proposed, since we observed the light properties related to three other categories. This study used mixed methods to identify the emotional value of a new design element. We suggest that the emotional categories derived and the proposed relationship model could be used to evaluate the product's light design.

• Education of Primary School Mathematics
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• v.16 no.1
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• pp.35-55
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• 2013

The purposes of this study were to development and verify the effect of educational program apply on STEAM for the mathematical prodigy. To accomplish these purposes literature review on development of the program and qualitative study were conducted. The mixed-model design was applied for this qualitative experimental study. The conclusions of this study were as follows. First, the program for mathematical prodigy education applied on the conceptual model of STEAM integration approach was developed. Second, a learning satisfaction about constitution of the workbook was lowly. Third, principal of STEAM was the best interest and difficult of the program applied on STEAM. Fourth, the creativity and problem solving ability was founded about angle and velocity of mathematical domain and making the Angrybirds Game on GeoGebra environment. In spite of difficulty about principal of the Angrybirds Game, confidence and satisfaction were founded about a result product.

• Journal of Korean Dental Science
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• v.15 no.1
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• pp.1-8
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• 2022

Purpose: Intraoral scanners, desktop scanners, and cone-beam computed tomography (CBCT) are being used in a complementary way for diagnosis and treatment planning. Limited patient-based results are available about dimensional reproducibility among different three-dimensional imaging systems. This study aimed to evaluate dimensional reproducibility among patient-derived digital models created from an intraoral scanner, desktop scanner, and two CBCT systems. Materials and Methods: Twenty-nine arches from sixteen patients who were candidates for implant treatments were enrolled. Different types of CBCT systems (KCT and VCT) were used before and after the surgery. Polyvinylsiloxane impressions were taken on the enrolled arches after the healing period. Gypsum casts were fabricated and scanned with an intraoral scanner (CIOS) and desktop scanner (MDS). Four test groups of digital models, each from CIOS, MDS, KCT, and VCT, respectively, were compared to the reference gypsum cast group. For comparison of linear measurements, intercanine and intermolar widths and left and right canine to molar lengths were measured on individual gypsum cast and digital models. All measurements were triplicated, and the averages were used for statistics. Bland-Altman plots were drawn to assess the degree of agreement between each test group with the reference gypsum cast group. A linear mixed model was used to analyze the fixed effect of the test groups compared to the reference group (α=0.05). Result: The Bland-Altman plots showed that the bias of each test group was -0.07 mm for CIOS, -0.07 mm for MDS, -0.21 mm for VCT, and -0.25 mm for KCT. The linear mixed model did not show significant differences between the test and reference groups (P>0.05). Conclusion: The linear distances measured on the digital models created from CIOS, MDS, and two CBCT systems showed slightly larger than the references but clinically acceptable reproducibility for diagnosis and treatment planning.