• The Korean Journal of Pain
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• v.9 no.1
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• pp.46-56
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• 1996

Many surgeons and anesthesiologists prefer using vasoconstrictor mixed with local anesthetic agent to reduce the incidence of side effects and prolong the duration of analgesia because most local anesthetic agents, except cocaine, were believed to possess vasodilating effect. However, some investigators recently reported vasoconstricting effect of local anesthetic agents. There is still controversy on the vasoactive effect of local anesthetic agents. So this study is aimed to clarify the vasoactive effect of local anesthetics in the animal model resembling clinical settings. Rabbits were anesthesized with ketamine and haloghane, and respirations were controlled with Harvard animal ventilator. Lidocaine (0.5%, 1.0%, 1.5%) and bupivacaine (0.125%, 0.25% and 0.5%) with or without 1:100,000 epinephrine were subdermaly injected on the femoral bupivacaine of the femoral artery were measured with Doppler flow meter in vivo. The mean arterial pressure, pulse rate, arterial blood gases, pH and level of serum electrolytes were measured at every 2 minute interval for 30 minutes. Results were as follows: 1) There was no significant vasoconstriction with 0.5% lidocaine and 0.125% bupivacaine. 2) Statistically significant (p<0.05) vasodilations were observed with lidocaine (1.0~2.0%) and bupivacaine (0.25~0.5%). 3) There were no changes on the duration of vasodilation induced by local anesthetic agents of various concentrations. 4) Onset of vasodilation induced by local anesthetic agents of high concentration were faster than that of lower concentrations. 5) In the mixed injection group of epinephrine and local anesthetic agent, the vasoconstriction induced by epinephrine was completely reversed by local anesthetics, approximately 5 minutes later. In conclusion, local anesthetic agents at dose exceeding 1.0% lidocaine and 0.25% bupivacaine increase local blood flow significantly in animal study in vivo which is applicable in human clinical settings. The increase blood flow may be due to dilatation of blood vessel. Further study on the analysis of association between amount of absorbed local anesthetics in blood vessels and dilatation of blood vessels is needed.

• The Korean Journal of Applied Statistics
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• v.34 no.5
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• pp.697-710
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• 2021

Relative error prediction is preferred over ordinary prediction methods when relative/percentile errors are regarded as important, especially in econometrics, software engineering and government official statistics. The relative error prediction techniques have been developed in linear/nonlinear regression, nonparametric regression using kernel regression smoother, and stationary time series models. However, random effect models have not been used in relative error prediction. The purpose of this article is to extend relative error prediction to some of generalized linear mixed model (GLMM) with panel data, which is the random effect models based on gamma, lognormal, or inverse gaussian distribution. For better understanding, the real auto insurance data is used to predict the claim size, and the best predictor and the best relative error predictor are comparatively illustrated.

• The Korean Journal of Applied Statistics
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• v.28 no.5
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• pp.1035-1046
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• 2015

Variance components models incorporate various random factors in the form of linear models. There are two experimental Layouts for the classification of factors under variance components models: nested classification and crossed classification. We consider two-way variance components models and investigate the effect of experimental Layout on the performance of model selection criteria AIC and BIC. The effect of experimental Layout is studied through a simulation study with various combinations of parameters in a systematic fashion. The simulation study shows differences in performance of model selection methods between the two classification. There is a particular tendency to prefer the smaller model than the true model when the variance component of a nested factor becomes relatively larger than a nesting factor that is persistent even when the sample size is not small.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.15 no.6
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• pp.41-49
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• 2016

To evaluate lubrication properties by surface roughness under boundary and mixed lubrication, a new approach is suggested by both asperity flow and contact with stochastic characteristics. Many researchers already have studied the effect of surface roughness on flow. But, it has become important to research of the phenomenon of asperities contact in surfaces because the growth of asperities contact area under heavy load conditions. In this paper, flow factors in the average flow model derived by Patir and Cheng were used, and a multi-asperity contact model was included to calculate lubrication properties of a surface with a randomly generated rough surface. A numerical analysis using the average Reynolds equation with both the average flow model and the asperity contact model was conducted, and the results were compared with those from previous research. The results showed that the influence of asperities on lubrication and the friction coefficient changed rapidly on application of contact model.

• Nuclear Engineering and Technology
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• v.56 no.5
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• pp.1902-1912
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• 2024

This paper presents results from system-level modeling of a water-based reactor cavity cooling system using RELAP5-3D. The computational model is benchmarked with experimental data from a half-scale RCCS test facility at Argonne National Laboratory. The model prediction is first compared with a two-phase oscillatory baseline experimental case where mixed accuracy is obtained. The model shows reasonable prediction of mass flow rate, pressure, and temperature but significant overprediction of void fraction. The model prediction is then compared with a fault case where the inlet of the risers is gradually reduced using a throttling valve. As the valve is closed, the model is able to predict some major flow phenomena observed in the experiment such as the dampening of oscillations, the reintroduction of oscillations, as well as boiling, flashing, and geysering in the risers. However, the timeline of these events are not well captured by the model. The model is also used to investigate the evolution of flow regime in the chimney. This work highlights that the semi-empirical constitutive relations used in RELAP-3D could have a strong influence on the accuracy of the model in two-phase oscillatory flows.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.25 no.3
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• pp.47-62
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• 2022

The Ministry of Environment has been working to reduce the impact on biodiversity, ecosystems, and social costs caused by soil runoff from highland Agricultural fields by setting up non-point pollution source management districts. To reduce soil loss, runoff path reduction technology has been applied, but it has been less cost effective. In addition, non-point pollution sources cause environmental conflicts in downstream areas, and recently highland Agricultural fields are becoming vulnerable to climate change. The Ministry of Environment is promoting the optimal management plan in earnest to convert arable land into forests and grasslands, but since non-point pollution is not a simple environmental problem, it is necessary to approach it from the aspect of NbS(Nature-Based Solution). In this study, a scenario for applying the nature-based solution was established for three subwatersheds west of Haean-myeon, Yanggu-gun, Gangwon-do. The soil loss distribution was spatialized through GeoWEPP and the amount of soil loss was compared for the non-point pollution reduction effect of mixed forests and grasslands. When cultivated land with a slope of 20% or more and ginseng fields were restored to perennial grasslands and mixed forests, non-point pollution reduction effects of about 32% and 29.000 tons compared to the current land use were shown. Also, it was confirmed that mixed forest rather than perennial grassland is an effective nature-based solution to reduce non-point pollution.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.519-519
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• 2023

Estuarine dams are a recent and global phenomenon. While estuarine dams can provide the benefit of improved freshwater resources, they can also alter estuarine processes. Due to the wide range of estuarine types and estuarine dam configurations, the effect of estuarine dams on estuaries is not well understood in general. To develop a systematic understanding of the effect of estuarine dam location and freshwater discharge interval on a range of estuarine types (strongly stratified, partially mixed, periodically stratified, and well-mixed), this study used a coupled hydrodynamic-sediment dynamic numerical model (COAWST) and compared flow, sediment transport, and morphological conditions in the pre- and post-dam estuaries. For each estuarine type, scenarios with dam locations at 20, 55 and 90 km from the mouth and discharge intervals of a discharge every 0.5, 3, and 7 days were investigated. The results were analyzed in terms of change in tide, river discharge, estuarine classification, and sediment flux mechanism. The estuarine dam location primarily affected the tide-dominated estuaries, and the resonance length was an important length scale affecting the tidal currents and Stokes return flow. When the location was less than the resonance length, the tidal currents and Stokes return flow were most reduced due to the loss of tidal prism, the dead-end channel, and the shift from mixed to standing tides. The discharge interval primarily affected the river-dominated estuaries, and the tidal cycle period was an important time scale. When the interval was greater than the tidal cycle period, notable seaward discharge pulses and freshwater fronts occurred. Dams located near the mouth with large discharge interval differed the most from their pre-dam condition based on the estuarine classification. Greater discharge intervals, associated with large discharge magnitudes, resulted in scour and seaward sediment flux in the river-dominated estuaries, and the dam located near the resonance length resulted in the greatest landward tidal pumping sediment flux and deposition in the tide-dominated estuaries.

• Journal of the Korean Operations Research and Management Science Society
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• v.33 no.1
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• pp.149-168
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• 2008

Many organizations have introduced information technology (IT) as an innovation to gain competitive advantages as business environments have become increasingly complex and rapidly changing. Despite the large investment of IT, there have been mixed results about whether IT creates business values. Considering that IT assimilation may play an important role in explaining IT productivity paradox, this study examines the formation of IT assimilation and its effect on the organizational performance. To do so, this study suggests a research model based on Innovation Diffusion Theory by incorporating organization system, communication channel, change acceptability, and innovation factors, and then attempts to empirically explore the role of IT assimilation for enhanced organizational performance using data collected at the organizational level. Structural equation analysis using AMOS provides significant support for part of proposed relationships. Specifically, we have found encouraging results on the role of IT assimilation by identifying its mediating effect on the organizational performance. Theoretical and practical implications of the findings are discussed accordingly.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.67-72
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• 2003

Numerical calculation has been performed to investigate the effect of inlet configuration on the growth rate of GaN layer on the heated susceptor. The conventional single inlet, where the gas is mixed by force in the inlet, is compared with separated flow inlet. Two-parallel gas flow $H_{2}$ and $NH_{3}$ are separated by a plate with finite length which are also parallel to the susceptor. The effect of separated plate length, carrier gas and flow rate of each precursor on the mixing of reactant gases and growth rate were investigated. Furthermore the three dimensional model is employed to predict the transverse variation of growth rate.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.2
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• pp.387-399
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• 2021

This study mainly aims to examine the effect of intangible assets on the value relevance of the Gulf Cooperation Council (GCC)-listed non-financial firms. This study tested three types of models by using a large sample of non-financial firms listed in GCC countries as emerging markets from 2008 to 2016. The types of models are accounting information (earnings per share and book value of share) without intangible assets model, intangible assets model, and accounting information (earnings per share and book value of share) with intangible assets model. Ordinary least square (OLS) shows mixed results as intangible assets improve the value relevance of accounting information positively in UAE and negatively in Kuwait but not in other countries. The study documents a robust positive relationship between intangible assets and earnings quality in terms of value relevance in KSA and Qatar. The findings provide implications for policymakers, investors, and managers. The results suggest that intangible assets can improve the value relevance in emerging markets, such as GCC, as the need to organize the requirements of information disclosures on intangible assets and provide great transparency and additional disclosure of information about intangible assets and their components.