• 제목/요약/키워드: Mixed-effect

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야채 및 과일추출물의 항산화작용과 산화적 염색체손상에 대한 억제효과 (Antioxidative Activity and Protection of Oxidative Chromosomal Damage by Vegetables, Fruits Extract and Their Functional Liquid Formulation)

  • 이승철;허찬;이승현;김현표;허문영
    • 약학회지
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    • 제48권2호
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    • pp.111-116
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    • 2004
  • The ethanol extracts of mixed vegetables (Bioactive Vegetables, BV), mixed fruits (Bioactive Fruits, BF) and their liquid formulation (Chungpae Plus , CP) were evaluated for their antioxidative and antigenotoxic activities. They were shown to possess the significant free radical scavenging effect against 1,1-diphenyl-2-picryl hydrazine (DPPH) radical generation and were revealed to show the inhibitory effect of lipid peroxidation as measured by malondialdehyde (MDA) formation although the potencies were not higher than those of vitamin C. They did not possess any pro-oxidant effect on bleomycin-Fe(III) dependent DNA degradation, whereas vitamin C showed strong pro-oxidant effect. Furthermore, oral administration of BV and BF inhibited micronucleated reticulocyte (MNRET) formation of mouse peripheral blood induced by KBrO3 treatment in vivo. CP also showed significant inhibition under same experimental condition. Therefore, the liquid formulation (CP) containing BV and BF may be a useful natural antioxidative and antigenotoxic agent by scavenging free radicals, inhibition of lipid peroxidation and protecting chromosomal damage.

근관세척액의 항균효과에 관한 연구 (A STUDY ON THE ANTIMICROBIAL EFFECT OF IRRIGATION SOLUTIONS)

  • 임미경;이정식
    • Restorative Dentistry and Endodontics
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    • 제15권1호
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    • pp.187-200
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    • 1990
  • The purpose of this study was to investigate antimicrobial effect of several irrigation solutions on 7 anaerobes and 2 aerobes, which are found frequently in infected root canals. The antimicrobial effects of normal saline, 3% $H_2O_2$, 0.5% & 3.5% NaOCl, 10% & 50% citric acid and mixed solutions of 3% $H_2O_2$ plus 3.5% NaOCl were compared. No. 80 paper points dipped in bacterial broth were soaked in each irrigation solutions and moved into thioglycolate broth, subcultured in agar plate for bacterial growth. The results were as follows: 1. Normal saline had no antimicrobial effect. 2. Mixed solutions of 3% $H_2O_2$ plus 3.5% NaOCl, 10% citric acid had relatively weak antimicrobial effect. 3.3% $H_2O_2$, 50% citric acid, 0.5% NaOCl showed relatively strong antimicrobial effect. 4. 3.5% NaOCl had the strongest antimicrobial effect among used 7 irrigation solutions.

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Antioxidative and antigenotoxic activity of vegetable and fruit extracts

  • Heo, Chan;Lee, Seung-Chul;Kim, Hyun-Pyo;Heo, Moon-Young
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.110.2-110.2
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    • 2003
  • The ethanol extracts of mixed vegetables (Bioactive V, BV), mixed fruits (Bioactive F, BF) and its liquid formulation (Chungpae Plus$\circledR$) were evaluated for their antioxidative and antigenotoxic activity. They were shown to possess the significant free radical scavenging effect against l,l-diphenyl-2-picryl hydrazine (DPPH) radical generation and were revealed to show the inhibitory effect of lipid peroxidation as measured by malondialdehyde (MDA) formation. (omitted)

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Comparison of the Suicide Attempt Characteristics Associated with Mixed and Non-Mixed Depression in Koreans

  • Choi, Hyeon-Seok;Kim, Sung-Jin;Nam, Sang-Hun;Jung, Do-Un;Moon, Jung-Joon;Kim, Yeon-Sue;Oh, Min-Kyung;Jeon, Dong-Wook;Ahn, Yong Min
    • 정신신체의학
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    • 제29권2호
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    • pp.199-206
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    • 2021
  • Objectives : This study aimed to compare the characteristics of suicide attempts among Korean patients with mixed and non-mixed depression. Methods : Patients who visited the emergency room due to a suicide attempt and participated in the Korean Cohort for the Model Predicting a Suicide and Suicide-related Behavior study were included. Using the Montgomery-Asberg Depression Rating Scale (MADRS) and Young Mania Rating Scale (YMRS), 111 patients were classified into the mixed depression (n=46) and non-mixed depression groups (n=65). The Koukopoulos Mixed Depression Rating Scale (KMDRS) score was calculated using the MADRS and YMRS scores. Suicide attempt characteristics were evaluated using the Columbia Suicidal Severity Rating Scale (C-SSRS) and Suicide Intent Scale (SIS). Results : In the mixed depression group, the reason item among the ideation intensity score of the C-SSRS was higher, and the deterrent item score was lower. Scores on the timing and suicide note items of the SIS were higher, and scores for overt communication items were lower in the mixed depression group. The KMDRS score was positively correlated with the C-SSRS ideation intensity and total SIS score. After adjusting for additional variables, the KMDRS scores had a significant effect on the C-SSRS ideation intensity and total SIS scores. Conclusions : The mixed depression group showed a difference in the intensity of suicidal ideation and suicidal intention compared to those in the non-mixed depression group. The overall suicidal ideation intensity and suicidal intention increased according to the degree of mixed depression.

혼합현실 기술 사용자 체험이 플로우와 지속사용의도에 미치는 효과 (The Effect of User Experience on Perceived Flow and Continuous Intentions to Use the Mixed Reality Technology)

  • 김은영;성희원
    • 한국의류학회지
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    • 제45권5호
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    • pp.907-921
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    • 2021
  • This study aims to predict causal relationships between experience economy, perceived flow, and continuous use intention in the mixed reality (MR) environment. A virtual fitting mirror with two modes (i.e., avatar and self-image) was selected for this study. A total of 200 samples was obtained in two sample frames: virtual fitting users in avatar mode (group 1, n = 119) and self-image mode (group 2, n = 81). The results showed that the experience economy consists of entertainment, education, esthetic, and escapism. The entertainment and esthetic experiences had positive effects on perceived flow, leading to continuous use intentions. For avatar mode, the entertainment and esthetic experiences had positive effects on continuous use intentions through the mediating effect of flow; and the education experience had a positive effect on the continuous intentions to use the MR technology. For self-image mode, the flow mediated the effect of entertainment on continuous use intentions, whereas education and escapism directly affected the intention to use the MR technology. The paper also discusses the theoretical and managerial implications of using MR technologies in fashion retailing.

Standing Wave Pressure Acting on the Mixed Type Breakwater

  • Oh, Young-Min;Lee, Kil-Seong;Chun, In-Sik
    • 한국해안해양공학회:학술대회논문집
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    • 한국해안해양공학회 1995년도 정기학술강연회 발표논문 초록집
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    • pp.120-121
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    • 1995
  • In the design of mixed type breakwater, the most important factor to be considered is the wave pressure. In particular, the standing wave pressure has a significant effect on the vertical wall breakwater or mixed type breakwater. Many wave pressure formulas were developed and the Goda's formula[1] was very frequently used among them by the coastal engineers due to its simplicity and accuracy. (omitted)

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Mixed Effects Kernel Binomial Regression

  • Hwang, Chang-Ha
    • Journal of the Korean Data and Information Science Society
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    • 제19권4호
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    • pp.1327-1334
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    • 2008
  • Mixed effect binomial regression models are widely used for analysis of correlated count data in which the response is the result of a series of one of two possible disjoint outcomes. In this paper, we consider kernel extensions with nonparametric fixed effects and parametric random effects. The estimation is through the penalized likelihood method based on kernel trick, and our focus is on the efficient computation and the effective hyperparameter selection. For the selection of hyperparameters, cross-validation techniques are employed. Examples illustrating usage and features of the proposed method are provided.

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원자흡수 분광법에 의한 칼슘분석에서 세륨의 해방효과에 관한 연구 (Studies on the Releasing Effect of Cerium in Calcium Analysis by Atomic Absorption Spectrometry)

  • 박기채;최희선;권수한
    • 대한화학회지
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    • 제29권2호
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    • pp.129-136
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    • 1985
  • 공기-아세틸렌 불꽃 원자 흡수분광법으로 칼슘분석을 하는 경우 비교적 방해가 큰 것은 지르코늄, 주석, 알루미늄, 안티몬 등 양이온과 황산이온, 바나듐산이온, 규산이온 등 음이온이다. 여기에 해방제로서 세륨을 사용하면 이들 방해 효과를 제거할 수 있음을 알게 되었다. 칼슘과 같은 농도($3.0 {\times} 10^{-4}$M)의 이 방해이온들에 의한 방해는 방해이온 농도의 2배의 세륨에 의하여 완전히 해방됨을 보았고 방해 양이온혼합물(지르코늄, 주석, 알루미늄, 안티몬), 방해음이온 혼합물(황산이온, 바나듐산이온, 규산이온)또는 방해양이온 음이온 혼합물의 방해는 각각의 양이온 혹은 음이온에 의한 방해보다 더 큰 방해를 주는데 세륨($1.5 {\times} 10^{-2}$M)에 의한 해방효과는 방해양이온, 음이온 혼합물의 농도가 각각 $3.0 {\times} 10^{-3}$M까지 증가하여도 거의 변하지 않고 좋았다.

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규정 이상의 회수수를 사용한 콘크리트의 내구성 및 강도 특성 (Durability and Strength Characteristics of Concrete Using Sludge Water above Specification)

  • 양은익;박진호;김강래;조규재
    • 콘크리트학회논문집
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    • 제18권2호
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    • pp.199-204
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    • 2006
  • 최근 환경오염과 처리비용의 문제로 레미콘(ready mixed concrete) 회수수를 배합수로 재이용하기 위한 연구가 진행되고 있다. 그러나 회수수를 너무 많이 이용할 경우 콘크리트의 품질이 저하 될 수 있다. 이런 이유로 KS표준규정에선 회수수 중 슬러지 고형성분의 혼입비율을 시멘트 중량의 3% 이하로 제한하고 있다. 따라서 본 연구에서는 규정이상의 슬러지 고형성분을 혼입한 경우, 콘크리트에 미치는 영향을 검토하였다. 실험결과에 따르면, 혼입율 증가에 따라 작업성은 떨어졌으나 강도발현은 좋게 나타났다. 또한 건조수축 및 동결융해 실험에서는 슬러지수 혼입에 따른 영향이 적은 것으로 나타났다.

백색잡음을 혼합한 게임음악이 전전두엽에 미치는 영향 (An Effect of the Prefrontal Lobe Influenced by Game Music Mixed with White Noise)

  • 최종윤;이대웅
    • 한국게임학회 논문지
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    • 제11권6호
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    • pp.3-11
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    • 2011
  • 디지털미디어의 사운드는 인간의 감각을 자극하여 커뮤니케이션을 수행한다. 소리 자극은 생리적 흥분을 가져오고 반응에 민감한 상태로 각성시키는데, 이는 심장박동, 혈압, 뇌파신호로 나타난다. 본 논문에서는 이완효과가 있는 백색잡음을 혼합한 게임음악과 백색잡음이 섞이지 않은 게임음악을 듣는 게임 플레이어의 뇌파변화를 검사했다. 실험은 두 그룹으로 나누어 진행되었으며 A 그룹은 백색잡음이 섞인 게임음악을, B 그룹은 백색잡음이 섞이지 않은 게임음악을 들으며 게임을 플레이했다. 두 그룹의 전전두엽 뇌파 변화를 측정한 결과 좌뇌에서는 백색 잡음의 이완효과가 나타났으며, 우뇌의 경우는 기대치에 미치지 못했다. 본 연구는 백색잡음의 이완효과를 이용한 기능성 심리치료 게임을 개발하기 위한 기본 연구가 될 것이다.