• The Korean Journal of Soil Zoology
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• v.6 no.1_2
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• pp.1-6
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• 2001

Although the earthworm is an important animal species capable of regenerating missing body part, earthworm regeneration is not well understood at the tissue, cell and molecular levels. In order to understand the developmental changes of blastema during earthworm tail regeneration, the formation and development blastema during regeneration was investigated by histological analysis. Within 1 day after amputation, dediffentiating blastemal cells appeared in coelomic side of longitudinal muscle layer. At 3 days postamputation, proliferating blastemal cells migrated into coelum and blastema was formed beneath wound epithelium around 7 days after amputation. Segmentation of blastema was observed around 2 weeks after amputation followed by redifferentiation of nephridium, intestine, setae and septa.

• Korean Journal of Plant Taxonomy
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• v.52 no.4
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• pp.214-218
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• 2022

Eleocharis R. Br. (Cyperaceae) is characterized by unbranched culms, one terminal spikelet, bisexual flowers, and bristly perianths, occurring mainly in circumboreal marshes and wetlands. There are about 250 species worldwide, and 15 taxa in Korea have been recognized. Chromosomes in Cyperaceae are known to be holocentric, missing constricted centromeres during cell division. For the first time, we report the chromosome counts of Eleocharis from Korean populations of E. attenuata f. laeviseta (Nakai) H. Hara (2n = 20); E. parvula (Roem. & Schult.) Link ex Bluff, Nees & Schauer (2n = 10); E. ussuriensis Zinserl. (2n = 16); and E. valleculosa var. setosa Ohwi (2n = 16). The populations exhibit variations in their chromosome sizes from ca.1.7 ㎛ to ca. 6 ㎛, categorized as gradient and bimodal karyotypes. The karyotypes observed are congruent with previous phylogenetic groups proposed. To clarify the traditional and phylogenetic classification of Korean Eleocharis, further taxonomic and chromosomal investigations with additional taxon sampling efforts are required.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.601-606
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• 2015

Background: Prostate cancer is predominately a disease of older men, with a median age of diagnosis of 68 years and 71% of cancer deaths occurring in those over 75 years of age. While prostate cancer screening is not recommended for men >70 years, fit elderly men with controlled comorbidities may have a relatively long life expectancy. We compare the use of age related PSA with the detection of primary malignant circulating prostate cells mCPCs to detect clinically significant PC in this population. Materials and Methods: All men undergoing PC screening with a PSA >4.0ng/ml underwent TRUS 12 core prostate biopsy (PB). Age, PSA, PB results defined as cancer/no-cancer, Gleason, number of positive cores and percentage infiltration were registered. Men had an 8ml blood sample taken for mCPC detection; mononuclear cells were obtained using differential gel centrifugation and mCPCs were identified using immunocytochemistry with anti-PSA and anti-P504S. A mCPC was defined as a cell expressing PSA and P504S; a positive test as at least one mCPC detected/sample. Diagnostic yields for subgroups were calculated and the number of avoided PBs registered. Esptein criteria were used to define small grade tumours. Results: A total of 610 men underwent PB, 398 of whom were aged <70yrs. Men over 70 yrs had: a higher median PSA, 6.24ng/ml versus 5.59ng/ml (p=0.04); and a higher frequency of cancer detected 90/212 (43%) versus 134/398 (34%) (p=0.032). Some 34/134 cancers in men <70yrs versus 22/90 (24%) of men >70yrs complied with criteria for active surveillance. CPC detection: 154/398 (39%) men <70yrs were CPC (+), specificity for cancer 86%, sensitivity 88%, 14/16 with a false (-) result had a small low grade PC. In men >70 years, 88/212 (42%) were CPC (+); specificity 92%, sensitivity 87%, 10/12 with a false (-) had small low grade tumours. False (+) results were more common in younger men 36/154 versus 10/88 (p<0.02). With a PSA cutoff of 6.5ng/ml, in men <70yrs, 108 PB would be avoided, missing 56 cancers of which 48 were clinically significant. Using CPC detection, 124 biopsies would be avoided, missing only 2 clinically significant cancers. In men >70 yrs using a PSA >6.5ng/ml would have resulted in 108 PB with 34 PC detected, of which 14(41%) were small low grade tumours. Conclusions: The use of CPC detection in the fit elderly significantly decreases the number of PBs without missing clinically significant cancers, indicating superiority to the use of age-related PSA.

• International journal of advanced smart convergence
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• v.10 no.1
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• pp.1-11
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• 2021

Document page segmentation is an important step in building a quality optical character recognition module. The study examined already existing work on the topic of page segmentation and focused on the development of a segmentation model that has greater functional significance for application in an organization, as well as broad capabilities for managing the quality of the model. The main problems of document segmentation were highlighted, which include a complex background of intersecting objects. As classes for detection, not only classic text, table and figure were selected, but also additional types, such as signature, logo and table without borders (or with partially missing borders). This made it possible to pose a non-trivial task of detecting non-standard document elements. The authors compared existing neural network architectures for object detection based on published research data. The most suitable architecture was RetinaNet. To ensure the possibility of quality control of the model, a method based on neural network modeling using the RetinaNet architecture is proposed. During the study, several models were built, the quality of which was assessed on the test sample using the Mean average Precision metric. The best result among the constructed algorithms was shown by a model that includes four neural networks: the focus of the first neural network on detecting tables and tables without borders, the second - seals and signatures, the third - pictures and logos, and the fourth - text. As a result of the analysis, it was revealed that the approach based on four neural networks showed the best results in accordance with the objectives of the study on the test sample in the context of most classes of detection. The method proposed in the article can be used to recognize other objects. A promising direction in which the analysis can be continued is the segmentation of tables; the areas of the table that differ in function will act as classes: heading, cell with a name, cell with data, empty cell.

• English Language & Literature Teaching
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• v.13 no.1
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• pp.47-66
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• 2007

Error analysis plays an important role because understanding the types of errors can give a better opportunity for both teachers and learners to recognize the nature of errors and ways of preventing them. This study looks into errors in the medical research abstracts written by 26 Koreans and also examines hedging expressions since hedging can be a necessary tactic in which the validity and objectivity of their claims is conveyed. The hedging expressions of these research abstracts are to be compared with those of Hyland (1996)'s study done on ENL academic writers of cell and molecular biology. The results of the study reveal that wrong word choice was the most commonly occurred errors, followed by prepositions, articles, adding and missing words. Many of these errors, except articles, seemed to derive from the native language interference. There were also run-on sentences, subject & verb agreement, tense, word order and minor errors. As for hedging, ESL medical writers seemed to use very limited hedging expressions and inappropriately strong modals. It is recommended to take variations of hedges using epistemic adverbials and adjectives to present their claims in a more valid and polite way. Limited verb choice was also noted. As for preventing or minimizing similar future errors, collocation practices in ESP focused on commonly used medical related words and expressions can be effective.

• Plant Biotechnology Reports
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• v.4 no.3
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• pp.193-199
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• 2010

An olive-green mutant was generated in Synechocystis sp. strain PCC 6803 by inactivation of the sll0396 gene. Whole-cell absorption spectra of the mutant revealed the missing of phycocyanin peak. An investigation of the low-temperature fluorescence emission spectra revealed that the $sll0396{\Omega}$ mutant has a reduced amount of phycocyanin. Western blot analysis showed that the mutant contained less phycocyanin ${\beta}$- and ${\alpha}$-subunits and lacked the 30- and 32-kDa linker polypeptides, and northern blot analysis revealed that the transcription of the 1.4-kb cpcBA gene encoding the phycocyanin ${\beta}$- and ${\alpha}$-subunits was lower in the mutant. The Sll0396 protein has a DNA-binding motif and shares homology with known response regulators. Our results indicate that Sll0396 plays a regulatory role in the transcription of the phycocyanin genes during phycobilisome synthesis.

• Journal of the Korea Institute of Military Science and Technology
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• v.14 no.1
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• pp.100-105
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• 2011

Generally, because received signals from radar are very bulky, the data are divided into manageable size called section, and sections are distributed into several digital signal processors. And then, target detection algorithms are applied simultaneously in each processor. CFAR(Constant False Alarm Rate) algorithm, which is the most popular target detection algorithm, can estimate accurate threshold values to determine which signals are targets or noises within center-cut of section allocated to each processor. However, its estimation precision is diminished in section edge data because of insufficient surrounding data to be referred. Especially this edge problem of CFAR is too serious if we have many sections to be processed, because it causes many false alarms in most every section edges. This paper describes false alarm issues on MCA(Minimum Cell Average)-CFAR, and proposes a false alarm elimination method by changing section size alternatively. Real received data from multi-function radar were used to evaluate a proposed method, and we show that our method drastically decreases false alarms without missing real targets, and improves detection performance.

• Bulletin of the Korean Chemical Society
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• v.32 no.8
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• pp.2623-2627
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• 2011

We investigated the surface structure and wetting behavior of octaneselenolate self-assembled monolayers (SAMs) on Au(111) formed in a 50 ${\mu}M$ ethanol solution according to immersion time, using scanning tunneling microscopy (STM) and an automatic contact angle (CA) goniometer. Closely-packed, well-ordered alkanethiol SAMs would form as the immersion time increased; unexpectedly, however, we observed the structural transition of octaneselenolate SAMs from a molecular row phase with a long-range order to a disordered phase with a high density of vacancy islands (VIs). Molecularly resolved STM imaging revealed that the missing-row ordered phase of the SAMs could be assigned as a $(6{\times}{\surd}3)R30^{\circ}$ superlattice containing three molecules in the rectangular unit cell. In addition, CA measurements showed that the structural order and defect density of VIs are closely related to the wetting behaviors of octaneselenolate SAMs on gold. In this study, we clearly demonstrate that interactions between the headgroups and gold surfaces play an important role in determining the physical properties and surface structure of SAMs.

• BMB Reports
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• v.30 no.4
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• pp.299-301
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• 1997

The asialoglycoprotein receptor (ASGPR) was the first described mammalian lectin that mediates the specific binding and internalization of galactose/N-acetylgalactosamine-terminating glycoproteins by hepatic parenchymal cells. H1 and H2 are known as essential subunits of the functional ASGPR. There were close similarities in ASGPR H2 subunits between cultured cell line HepG2 and normal human liver cells including identical sequences at both termini. It was therefore expected that there may be some similarities between the subunits from normal liver cells and fetal liver cells. The two subunits of human fetal liver ASGPR. designated FL-H1 and FL-H2. were cloned from cDNA library by peR and the sequences were compared with the known HI and H2 sequences of HepG2, and the H1 sequence of nornal human liver cells. The results showed that FL-H1 was identical to H1 of HepG2. Whereas FL-H2 contains a 15-bp miniexon, but missing 57-bp at the near upstream from the membrane-spanning domain compared to H2 of HepG2 and normal human liver cells indicating that FL-H2 resulted from a differential splicing compared to HepG2 and normal liver cells.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.5 no.1
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• pp.18-22
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• 2005

Pompe disease is a genetic disorder caused by a deficiency of acid ${\alpha}$-glucosidase (GAA). This enzyme defect results in lysosomal glycogen accumulation in multiple tissues and cell types, with cardiac, skeletal, and smooth muscle cells the most seriously affected. Infantile-onset Pompe disease is uniformly lethal. Affected infants present in the first few months of life with hypotonia, generalized muscle weakness, and a hypertrophic cardiomyopathy, followed by death from cardiorespiratory failure or respiratory infection, usually by 1 year of age. Late-onset forms is characterized by a lack of severe cardiac involvement and a less severe short-term prognosis. Enzyme replacement therapy for Pompe disease is intended to address directly the underlying metabolic defect via intravenous infusions of recombinant human GAA to provide the missing enzyme. We experienced one case of Pompe disease in 3-years old boy that has improved his exercise ability and cardiac function after GAA enzyme replacement therapy.