• 한국진공학회지
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• 제22권2호
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• pp.55-65
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• 2013

본 연구에서는, 동시에 넓은 면적을 조사할 수 있는 형태의 유전체 장벽 방전을 이용한 대기압 면방전 플라즈마 발생장치를 이용하여 곰팡이의 살균 실험을 수행하였다. 실험에 사용한 면방전 플라즈마 발생장치의 파워는 사인파 교류전원을 이용하였으며, 1.4~2.3 kV의 방전전압을 가진다. 또한, 유전체 전기용량의 특성으로 인하여 전압과 전류의 위상차는 약 80도를 갖는다. 생물시료에 미치는 온도의 영향은 공랭식 쿨러를 사용하여 유전체의 열을 배출함으로써 최소화 하였으며, 시료의 온도는 온도측정장치를 사용하여 쿨러(Cooler) 작동 시 최대 10분간 플라즈마를 발생시켜도 37도가 넘지 않음을 확인하였다. 플라즈마에서 생성되는 활성종중 오존($O_3$)의 양은 플라즈마 발생부로부터 1 cm 이내에서 약 25~30 ppm이 측정되었으며, 150 cm 떨어진 지점에서도 5 ppm 정도 측정되었다. 그에 비해 일산화질소(NO)나 이산화질소($NO_2$)는 거의 검지되지 않음을 확인하였다. 증류수 속에 담긴 빵 곰팡이 포자를 면방전 플라즈마 발생장치로 처리하였을 때, 포자의 발아율은 처리시간 및 출력파워가 증가함에 따라 급격히 감소하였으며, MTT (3-(4,5-dimethy lthiazol-2yl)-2,5-diphenyl-2H-tetrazolium bromide) 측정법을 통해 분석한 미토콘드리아 활성도도 처리시간과 출력파워에 비례하여 감소함을 보았다. 반면 포자를 Vogel's minimal 배양액에 넣고 플라즈마 처리를 하면, 앞의 실험과 달리 살균효과가 미비함을 보였는데, 이를 통해 포자를 둘러싸고 있는 환경이 플라즈마의 살균효과에 영향을 미치는 것으로 보여진다. 본 연구를 통하여 유전체 장벽을 이용한 면방전 플라즈마 발생장치는 플라즈마 제트(jet)와는 달리 직접적인 접촉 없이도 미생물 살균이 가능하다는 것을 보여주었으며, 이는 면방전 플라즈마 발생장치로부터 발생하는 활성종들이 곰팡이와 같은 미생물의 비활성화에 주요역할을 하기 때문이라고 본다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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• pp.2365-2372
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• 2011

BLDC 모터와 같은 동기전동기에서 소음과 진동의 원인이 되는 코깅토크는 전동기내의 비 균일 토크로서 전동기 시스템의 자기 에너지가 최소인 위치로 이동하려는 접선방향의 힘으로 부하전류와 상관없이 회전자 영구자석과 고정자 슬롯의 상호작용에 의해 발생한다. 이러한 코깅토크는 전동기의 소음과 진동의 주요 원인이 되므로 전동기 설계 시 반드시 고려해야 한다. 코깅토크는 영구자석이 부착된 회전자에 의하여 공극 중에 비교적 저차의 고조파 자속밀도와 고정자 철심 슬롯의 상호작용으로 발생한다는 점을 중시하여 본 논문에서는 실험계획법의 일종인 반응표면 법을 사용하여 코깅토크를 저감하는 방법에 대해 제시하였다.

• International Journal of Precision Engineering and Manufacturing
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• 제9권3호
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• pp.68-71
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• 2008

Transdermal and topical drug delivery with minimal tissue damage has been an area of vigorous research for a number of years. Our research team has initiated the development of an effective method for delivering drug particles across the skin (transdermal) for systemic circulation, and to localized (topical) areas. The device consists of a micro particle acceleration system based on laser ablation that can be integrated with endoscopic surgical techniques. A layer of micro particles is deposited on the surface of a thin metal foil. The rear side of the foil is irradiated with a laser beam, which generates a shockwave that travels through the foil. When the shockwave reaches the end of the foil, it is reflected as an expansion wave and causes instantaneous deformation of the foil in the opposite direction. Due to this sudden deformation, the microparticles are ejected from the foil at very high speeds, and therefore have sufficient momentum to penetrate soft body tissues. We have demonstrated this by successfully delivering cobalt particles $3\;{\mu}m$ in diameter into gelatin models that represent soft tissue with remarkable penetration depth.

• 산업경영시스템학회지
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• 제5권7호
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• pp.9-15
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• 1982

The rectilinear-distance location problem combines the property of being a very appropriate distance measure for a large number of location problems and the property of being very simple to treat analytically. An obvious question to be asked at the optimal point which is obtained by the rectilinear distance method is, "what if the point is not available as a location site\ulcorner." The point may, for example, be inaccessible or may coincide with the location of another structure, a river, or a municipal park. In this case, one approach that may be employed is to construct contour lines (also called iso-cost or level curves) of the cost function. Contour lines provide considerable insight into the shape of the surface of the total cost function as well as a useful means of evaluating alternative locations for the new facility. But, when there is an obstacle which divides the application area into two. The optimal location(which is acquired by the rectilinear distance method) is not coincide with the minimal cost point and the contour line is occasionally of no use, this paper shows the method of finding a way to decide an optimal point of single facility location in this case.this case.

• 대한기계학회논문집B
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• 제25권3호
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• pp.322-329
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• 2001

A study of the shock wave turbulent boundary layer interaction is presented. The focus of the study is the interactions of the shock waves with the turbulent boundary layer on the falt plate. Three examples are investigated. The computations are performed, using mixed explicit-implicit generalized Galerkin finite element method. The linear equations at each time step are solved by a preconditioned GMRES algorithm. Numerical results indicate that the implicit scheme converges to the asymptotic steady state much faster than the explicit counterpart. The computed surface pressures and skin friction coefficients display good agreement with experimental data. The flowfield manifests a complex shock wave system and a pair of counter-rotating vortices.

• The Korean Journal of Physiology
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• 제2권2호
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• pp.63-73
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• 1968

It is well known that mammalian alveolar membrane is covered with a very thin layer of surfactant film which characteristically reduces surface tension of alveolar membrane, and maintains alveolar stability. Since Clements in 1957 demonstrated that the surfactant is extractable by mincing the lung tissue in saline, various studies on the subject have been succeeded by many workers. However, the effect of radiation on the surfactant is not well clarified. Present study was attempted to observe the effect of x-irradiation on the activity of surfactant in rabbits. X-ray in dose of 300 r, 600 r or 900 r was irradiated to the chest of rabbits. The lung was removed from normal or irradiated rabbits sacrificed by arterial blood shedding, and lung-saline extract, adding 3 grams of lung tissue to 50 mili-liters of saline, was prepared by means of Vertis homogenizer. Tension-area diagram of lung extract was recorded automatically by a modified Langmuir-Wilhelmy balance with a synchronized recording system designed in this department. The surface tension of lung extract was measured at 1st, 2 nd, 3 rd, 7 th and 15 th post-radiation day in 300 r irradiated group, at 3 rd, 7 th and 15 th post-radiation day in 600 r irradiated group, 3 rd and 7 th post-radiation day in 900 r irradiated group respectively. For the histo-pathological study, lung tissue preparations were made in all irradiatiated groups on the day of experiment and in normal group. The results obtained are summarized as follows: 1. The minimal surface tension, maximal surface tension and stability index of normal rabbits lung extracts were 7.68 dynes/cm, 38.84 dynes/cm, and 1.39 respectively. 2. The activity of surfactant was depressed prominently by x-irradiation. However, increase in the dose of x-irradiation did not show any significant change in the degree of surfactant activity suppression. The most marked depression in surfactant was observed at the third post-radiation day in all irradiated groups. 3. Activity of surfactant depressed by x-irradiation showed a tendency of recovering to normal on 15 th post-radiation day. 4. The tendency of change in activity of surfactant following x-irradiation was somewhat correlative with histo-pathological changes. But the degree of depression of surfactant by x-irradiation did not correspond to the degree of histo-pathological changes, and recovery of lung tissue from radiation damage, tissue edema and congestion, seemed to be followed by restoration of surfactant activity. 5. The width of the tension-area diagram was measured at the surface area of 40% in lung extract of normal and x-irradiated rabbits. And it was found that the changes of the width corresponded well with that of minimum surface tension and of stability index in all normal and x-irradiated groups.

• 한국정보과학회논문지:시스템및이론
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• 제27권5호
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• pp.441-449
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• 2000

이진 볼륨 데이타(binary volume data)는 외과 수술 시뮬레이션(surgical simulation)이나 컬러 볼륨 렌더링과 같이 그레이-스케일 볼륨(gray-scale volume)을 이용하기에는 부적절한 분야에서 유용 하게 사용된다. 본 논문에서는 이진 볼륨을 효과적으로 표현하기 위해서 새로운 자료구조인 슬라이스 기반 이진 쉘(SBS : Slice-based Binary Shell)을 제안하고, 이 자료구조를 이용한 렌더링 알고리즘도 함께 제시한다. 슬라이스 기반 이진 쉘은 렌더링을 위해 필요한 최소한의 표면 복셀(surface voxel)들을 슬라이스 순으로 저장하고 복셀 좌표의 직접 계산을 가능하게 하기 때문에, 다중 개체(multiple objects)를 포함하고 있는 볼륨을 렌더링할 때 매우 효율적이다. 본 논문에서 제시하고 있는 슬라이스 기반 이진 쉘의 렌더링 알고리즘은 특별한 렌더링 가속 하드웨어가 없는 PC에서 100개 이상의 이진 개체들을 1초 내에 렌더링할 수 있다.

• 한국물환경학회지
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• 제22권6호
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• pp.991-995
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• 2006

The layered double hydroxide with the insertion of chloride ions (LDH-Cl), which was synthesized by the co-precipitation method, was applied to investigate the fundamental aspects of the absorptive agent for phosphate removal from wastewater. The adsorption capacity was best described by the Langmuir-FreundIich isotherm, and the estimated isotherm parameters indicate that the LDH-CI capacity for the phosphate removal is much higher than that observed using a natural adsorbent material such iron oxide tailing. The kinetic experiment also showed that the LDH-Cl adsorption reaction rapidly at the adsorptive rate of 0.55 mg-P/g-LDH/min, implying that this adsorbent can be of use in the full-scale applications. The pH had a minimal effect on the LDH adsorption capacity in the range of 5 to 11, although the capacity dropped at the low pHs because of the change in LDH surface properties. Furthermore, other anions such as $Cl^-$ and $NO_3{^-}$ commonly found in the wastewater streams insignificantly affected the phosphate removal efficiencies, while $HCO_3{^-}$ ions had a negative effect on the LDH adsorption capacity due to its high selectivity. The phosphate removal experiment using the actual secondary effluent from a wastewater treatment plant showed the similar decrease in adsorption capacity, indicating that the bicarbonate ions in the wastewater were competing with phosphate for the adsorptive site in the surface of the LDH-Cl. Overall, the synthetic adsorbent material, LDH-Cl, can be a feasible alternative over other conventional chemical agents, since the LDH-Cl exhibits the high phosphate removal capacity with the low sensitivity to other environmental conditions.

• Bulletin of the Korean Chemical Society
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• 제24권3호
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• pp.299-305
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• 2003

Physical properties and microstructure of new coumarin 4 doped $SiO_2$-PDMS ORMOSILs, synthesized by one-step (OS, acid-catalysis) and two-step (TS, acid-base catalysis) routes of sol-gel method with varying pH (0.6 to 7) and dye content $(5\;{times}\;10^{-4}\;to\;5{\times}\;10^{-2}\;mole)$, are reported. BET, UV-visible spectroscopy and SEM were used for characterizations. The increase in acid or base concentration increased the size of pores and aggregated silica particles. The samples with pH ≤ 2.5 were transparent and attributed to the small size of pores (~20 Å) and silica particles. The samples with pH > 2.5 were translucent or opaque due to non-uniform pore system formed by voids and large aggregated silica particles. The surface area was found a key factor controlling the interactions between the gel matrix and the dye. The OS samples with the highest dye concentration exhibited the minimal values of pore size, surface area and silica particle size, resulting in the concentration-quenching phenomenon.

• 한국전문물리치료학회지
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• 제23권1호
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• pp.87-93
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• 2016

Background: Posture balance control is the ability to maintain the body's center of gravity in the minimal postural sway state on a supportive surface. This ability is obtained through a complicated process of sensing the movements of the human body through sensory organs and then integrating the information into the central nervous system and reacting to the musculoskeletal system and the support action of the musculoskeletal system. Motor function, including coordination, motor, and vision, vestibular sense, and sensory function, including proprioception, should act in an integrated way. However, more than half of stroke patients have motor, sensory, cognitive, and emotional disorders for a long time. Motor and sensory disorders cause the greatest difficulty in postural control among stroke patients. Objects: The purpose of this study is to determine the effect of visual and somatosensory information on postural sway in stroke patients and carrying out a kinematic analysis using a tri-axial accelerometer and a quantitative assessment. Methods: Thirty-four subjects posed four stance condition was accepted various sensory information for counterbalance. This experiment referred to the computerized dynamic posturography assessments and was redesigned four condition blocking visual and somatosensory information. To measure the postural sway of the subjects' trunk, a wireless tri-axial accelerometer was used by signal vector magnitude value. Ony-way measure analysis of variance was performed among four condition. Results: There were significant differences when somatosensory information input blocked (p<.05). Conclusion: The sensory significantly affecting the balance ability of stroke patients is somatosensory, and the amount of actual movement of the trunk could be objectively compared and analyzed through quantitative figures using a tri-axial accelerometer for balance ability.