• Biomolecules & Therapeutics
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• v.24 no.4
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• pp.371-379
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• 2016

Store-operated calcium entry (SOCE), a major mode of extracellular calcium entry, plays roles in a variety of cell activities. Accumulating evidence indicates that the intracellular calcium ion concentration and calcium signaling are critical for the responses induced by oxidative stress. The present study was designed to investigate the potential effect of SOCE inhibition on $H_2O_2$-induced apoptosis in endothelial progenitor cells (EPCs), which are the predominant cells involved in endothelial repair. The results showed that $H_2O_2$-induced EPC apoptosis was reversed by SOCE inhibition induced either using the SOCE antagonist ML-9 or via silencing of stromal interaction molecule 1 (STIM1), a component of SOCE. Furthermore, SOCE inhibition repressed the increases in intracellular reactive oxygen species (ROS) levels and endoplasmic reticulum (ER) stress and ameliorated the mitochondrial dysfunction caused by $H_2O_2$. Our findings provide evidence that SOCE inhibition exerts a protective effect on EPCs in response to oxidative stress induced by $H_2O_2$ and may serve as a potential therapeutic strategy against vascular endothelial injury.

• The Journal of the Convergence on Culture Technology
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• v.6 no.4
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• pp.209-217
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• 2020

North Korea has steadily implemented defense reforms to strengthen its national defense capabilities, and in particular, has made military technology development and military industrial capability strengthening as the focus of national defense reform. North Korea's defense reform ultimately aimed at securing nuclear posture, and as technical achievements accumulated in the Kim Jung-Un era, it led to the development of military strength such as hydrogen bombs and ICBM/SLBM. Having secured nuclear capability, North Korea is also pursuing a symmetricality in the conventional military strength by securing a strategic advantage by pursuing the modernization of the conventional weapon systems through defense reform again. Up to now, North Korea's defense reform has succeeded in establishing a new ruling system for Kim Jung-Un and creating a driving force for negotiations with the United States.

• Convergence Security Journal
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• v.14 no.3_1
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• pp.79-89
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• 2014

North Korea's provocations is continued. Although Kim Il Sung, Kim Jong Il, Kim Jong Un regime was shift. The crisis is activated, but that there are no changes. Until now, there are the possibilities of war in the Korean peninsula. If we analyse a major provoked crisis committed by North Korea, the enemy's intention is clear. Since the Korean War, South and North Koreas remain limited military conflict continued. North Korea's provocative behavior so far can be summarized as the following. First, the provocative form has changed variously. Second, the risk analysis of the case, the goal is most often provoked by the military purposes. Third, North Korea is a war and peace strategy on both sides. Fourth, try to cover up the provocation. Each crisis event occurs when the peninsula side of North Korea by hiding his intention to blame the behavior of the operation has been shown to act.

• Maritime Security
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• v.7 no.1
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• pp.61-96
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• 2023

Amidst the ongoing instability and military tensions between North and South Korea, it is essential for us to comprehend and assess North Korea's military capabilities, while preparing for potential contingencies through military reinforcement. However, to conduct a comprehensive analysis of the military balance on the Korean Peninsula, it is imperative to move beyond simplistic quantitative comparisons of combat capabilities and embrace a broader perspective, which includes qualitative comparisons of military strength, operational capabilities, and a nation's ability to wage war. To address this need, this study employs the method of "Net Assessment" to evaluate the relative combat power of South and North Korean conventional naval forces, with a particular focus on surface combatants. This evaluation involves both quantitative and qualitative comparisons of military assets (personnel and equipment) and intangible factors (naval strategies, geography, etc.). By conducting a holistic assessment, the research aims to identify and analyze strategic asymmetries that may exist between the two navies.

• Strategy21
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• s.45
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• pp.33-59
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• 2019

There have many research papers to see China's evolution of maritime strategy and naval modernization in terms of its naval mind-set. However, this article focuses on assessing how China uses its all sorts of maritime strength to achieve 'a building maritime great power.' The aim of the article is to introduce a new perspective to this debate by analysing China's diversified ma maritime capabilities and a new way of implementation in maritime security strategy. In recent years, China has been developing not only unpredictable maritime military capabilities but also maritime supporting forces - Coast Guard and Maritime Militia. And recently China adopted up-to-date operational concept aimed at gaining military superiority in Asia-Pacific waters. By taking salami slicing strategy, gray zone strategy and cabbage strategy, China has been trying to exercise surpassing influences in regional maritime area, also in western Pacific region. This article provides a stepping stone to comprehend the aspect of China's recent maritime strategic actions, especially in Yellow Sea. In conclusion, this article suggests some policy recommendations for countering China's coercive maritime strategy. First, Korea should make sure a strategic concept of maritime security, instead of land warfare focused strategic concept. Second, it is needed to set up suitable naval forces for actively responding to neighbor nation's offensive actions.

• Journal of the military operations research society of Korea
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• v.17 no.2
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• pp.16-30
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• 1991

Data from a series of four studies on leadership behavior are analyzed and compared to identify effective patterns of leadership behavior for platoon leaders and battalion commanders in ROK Army. Multiple-method research strategy is utilized in four studies to overcome some of the limitations of previous researches. Two of four studies employ a questionnaire method, and the rest use content analysis of critical incidents. Important behaviors for leadership effectiveness in both platoon leaders and battalion commanders include Supporting and Motivating Task Commitment. However, Developing and Monitoring Operations are only important in platoon level, and Planning & Organizing and Recognizing & Rewarding only in battalion level. Most discrepancies in results among studies can be explained in terms of either method effects or situational differences in role requirements for leaders.

• Journal of the Korea Institute of Military Science and Technology
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• v.12 no.5
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• pp.557-562
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• 2009

Weapon system currently considers the research about effect analysis including cost effectiveness methodology for a budget management and an achievement of the military strategy goal. So that, this study considers the theoretical background, strength and weakness of several Multi-Criteria Decision Making, and an effect analysis of weapon system. And AHP(Analytic Hierarchy Process) is selected for the best effect analysis methodology of weapon system. Therefore, we applied AHP to the case study of the new generation Multiple Launcher Rocket System, performing the analysis of cost effectiveness methodology. Using AHP and cost effectiveness methodology, we propose the actual and proper decision making result.

• Journal of Contemporary Eastern Asia
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• v.15 no.2
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• pp.191-210
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• 2016

While general belief is that the military alliances are stable and rigid, the authors argue that the states are far more flexible in their behavior and often act against their alliances. This paper looks at states' behavior in the UN GA and looks how it is reflected in participation in military alliances during three periods of history since 1976 to this day. The authors illustrate the need to consider the network representation of co-sponsoring groups in General Assembly votes. They find significant support for their argument, indicating that social aspects can be extended beyond alliances. An application of social network analysis shows some unexpected affiliations in UN GA. If the UN GA is the "true" nature of these countries' alliance strategies, then it might suggest some significant defections and interesting association.

• Journal of Energy Engineering
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• v.28 no.1
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• pp.30-36
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• 2019

The military has developed and operated a variety of military vehicles. Among them, medium tactical vehicles are developed as vehicles suitable for transporting troops, replacing existing military trucks, which have a significant impact on infantry forces' combat capability. Applying technology to increase fuel efficiency to these critical weapons systems, medium tactical vehicles, increases the distance range, which can reduce effective operational performance and oil costs. In this study, a measure was taken to improve the distance range of Medium Tactical Vehicles by applying an oil temperature control strategy to increase fuel efficiency.

• Korea and Global Affairs
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• v.1 no.2
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• pp.171-208
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• 2017

This paper is to analyze the type characteristics and prospects of the North Korean nuclear strategy. To this end, the paper is composed of 5 chapters titled introduction; the concept and type of nuclear strategy; the nuclear capabilities of North Korea and the declarative nuclear strategy; the operational characteristics and prospects of the North Korean nuclear strategy; and conclusion. Recently, the deployment of nuclear weapons and the enhancement of nuclear capabilities in North Korea have raised serious problems in our security and military preparedness. Nuclear strategy means military strategy related to the organization, deployment and operation of nuclear weapons. The study of North Korea's nuclear strategy begins with a very realistic assumption that the nuclear arsenal of North Korea has been substantiated. It is a measure based on North Korea's nuclear arsenal that our defense authorities present the concepts of preemptive attack, missile defense, and mass retaliation as countermeasures against the North Korean nuclear issue and are in the process of introducing and deploying them. The declared nuclear declaration strategy of the DPRK is summarized as: (1)Nuclear deterrence and retaliation strategy under the (North Korea's) Nuclear Weapons Act, (2)Nuclear preemptive aggression, (3)The principle of 'no first use' of nuclear weapons in the 7th Congress. And the intentions and operational characteristics of the North Korean nuclear strategy are as follows: (1)Avoiding blame through imitation of existing nuclear state practices, (2)Favoring of nuclear strategy through declarative nuclear strategy, (3)Non-settlement of nuclear strategy due to gap between nuclear capability and nuclear posture. North Korea has declared itself a nuclear-weapon state through the revised Constitution(2012.7), the Line of 'Construction of the Nuclear Armed Forces and the Economy'(2013.3), and the Nuclear Weapons Act(2013.4). However, the status of "nuclear nations" can only be granted by the NPT, which is already a closed system. Realistically, a robust ROK-US alliance and close US-ROK cooperation are crucial to curbing and overcoming the North Korean nuclear threat we face. On this basis, it is essential not only to deter North Korea's nuclear attacks, but also to establish and implement our own short-term, middle-term and long-term political and military countermeasures for North Korea's denuclearization and disarmament.