• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3355-3360
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• 2015

Background: Zinc transporters have been considered as essential regulators in many cancers; however, their mechanisms remain unknown, especially in gliomas. Isocitrate dehydrogenase 1(IDH1) mutation is crucial to glioma. This study aimed to investigate whether zinc transporters are correlated with glioma grade and IDH1 mutation status. Materials and Methods: IDH1 mutation status and mRNA expression of four zinc transporters (ZIP4, ZIP9, ZIP11, and ZnT9) were determined by subjecting a panel of 74 glioma tissue samples to quantitative real-time PCR and pyrosequencing. The correlations between the expression levels of these zinc transporter genes and the grade of glioma, as well as IDH1 mutation status, were investigated. Results: Among the four zinc transporter genes, high ZIP4 expression and low ZIP11 expression were significantly associated with higher grade (grades III and IV) tumors compared with lower grade (grades I and II) counterparts (p<0.0001). However, only ZIP11 exhibited weak correlation with IDH1 mutation status (p=0.045). Samples with mutations in IDH1 displayed higher ZIP11 expression than those without IDH1 mutations. Conclusions: This finding indicated that zinc transporters may interact with IDH1 mutation by direct modulation or action in some shared pathways or genes to promote the development of glioma. Zinc transporters may play an important role in glioma. ZIP4 and ZIP11 are promising molecular diagnostic markers and novel therapeutic targets. Nevertheless, the detailed biological function of zinc transporters and the mechanism of the potential interaction between ZIP11 and IDH1 mutation in gliomagenesis should be further investigated.

• 수산해양교육연구
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• 제13권2호
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• pp.178-193
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• 2001

This paper is written for the aim of the system improvement to the activation of industrial man power in fisheries on the basis of '73 military special except system (MSES). As the results of the purpose, several points to be improved are as follows : 1. It is necessary to reminder on the important of man power maintenance by the cooperative system between industry and school. 2. MSES should be known to the people broadly and positively through the Korea pelagic fishery association and related industry, for example, their internet homepages. 3. The students should be opened the choice opportunity to applicant to lower license grade than their general study level. 4. More companies will be relaxed the restricted items upon new criteria about the nominated companies, revised system on March 27, 2001. 5. If any nominated company has unemployed man power under the system, it entrust the power of attorney in military office to other recommended authority or association for the purpose of the prompt performance to other nominated companies.

• 대한치과기공학회지
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• 제33권4호
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• pp.427-440
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• 2011

Purpose: The following research analyzes the causes of major selection and career decision of students studying dental technology. It is to be used as basic data for the management of career improvement program. Methods: The survey has been processed to 490 college students studying Dental Technology in D-college. Questionnaire consists of major selection confidence sheet (14 items) and career decision confidence sheet (18 items) and was scored with 5-points per question. The collected data was analyzed by the statistical program: SAS V8 for Windows. To test for significance on each item, p < 0.05 has been decided as a standard. Results: The analysis of result about the level of confidence on major selection has valid difference by genders, serving military service or not, experience of studying one more year to enter the college or not, making career decision and grade. The analysis of result about career decision has valid difference by gender, serving military service, career decision, day and night course, age and native place. Conclusion: We develop the career advice program and manage it effectively, the confidence on the major selection and pride about its faculty will be high to dental technology students.

• International Journal of Advanced Culture Technology
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• 제11권2호
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• pp.73-81
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• 2023

We conducted a survey related to study methods to identify the factors that have an influence on the academic achievement of university students and analyzed the results of this survey for correlation with students' GPA, which represents academic achievement. Test preparation and effective study habits were found to be the most important factors in overall student achievement. However, when divided by grade, maintaining health and satisfaction with school life are the most important factors for sophomores. Rather, in grades 3 and 4, time spent maintaining health is negatively reflected in improving academic achievement. Divided into gender, male students review or daily academic effort is an important factor in academic achievement, but in the case of female students, there is no difference in relative academic achievement because the amount of review and academic effort are small. For students who have experienced military service, review and test preparation are important to academic achievement, but for students who have not experienced military service, review has no effect on relative academic achievement.

• 간호행정학회지
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• 제3권1호
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• pp.37-50
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• 1997

The purpose of this study was to identify the gap between need-level and demonstration-level in nursing managerial competencies. In addition, the study proposes solutions to narrow this gap. The results of this study are as follows : 1) The mean score for need-level of each item was 4.0, and for demonstration-level, 3.5. This indicates that military hospital head nurses demonstrate a higher level of managerial competencies than the moderate level on all items. But items which were related to resource/ cost/ information managament, staff development management and professionalism management got relatively low ratings in the need-level. 2) The mean score for need-level of each category was 4.14, and for demonstration-level, 3.53. Categories on the individual dimension got a higher rating than categories on the group or organization dimension in both need-level and demonstration level. 3) The gap between need-level and demonstration-level appeared in all items(p<.05) and categories(p<.001). Although the gap was relatively low, it indicates that it is essential to plan a developmemt program for all nursing management competencies for military hospital head nurses. 4) There were significant differences in the gap between need-level and demonstration-level according to specific characteristics of the subjects. The gap did not appear in many categories on the individual dimension where the number of nursing staff was more than 10, a major grade, ICU head nurse or for head nurses having a long career. 5) Need-level and demonstration-level showed a difference according to specific characteristics of the subjects, because need-level and demonstration-level were higher where the number of nursing staff was more than 10, a major grade, and for ICU or Medical ward head nurses. The categories which showed need-level difference and demonstration-level differences according to specific characteristics of the subjects existed almostly completely in the group and organization dimension. Gap-level differences according to the number of hospital bed existed in only two categories. 6) The general causes of the gap were indicated to be 'Knowledge/ skill/ experience deficit', 'Limitation of rules and systems/ Inappropriate organizational environment' for most items, categories, and dimensions. The results of this study indicate that extensive competency developing strategies must be developed, because a gap was found in all items and categories. Specially, there is a need to concentrate attention on competencies in the group and organizational dimension which had a wider gap level. And it is important to take an individual approach according to the cause for each gap. In order to produce effective competency developing strategies, top managers must have sinsights into the importance of nursing staff development and nursing officer's efforts to develop themselves must be achieved. Further multi-dimensional(education, personnel-policy, nursing/ organizational environment) solutions to the gap must be developed and utilized.

• International Journal of Advanced Culture Technology
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• 제10권1호
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• pp.81-96
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• 2022

Based on a survey conducted on 125 students in the Department of Computer Engineering at K University, the following results were obtained by analyzing ways to improve academic ability. Male students should pay more attention to grade points management than female students before completing their military service. Students with high self-assessed academic ability score higher than students with low self-assessed academic ability. As long as students don't spend too much time, a student's part-time job is not an obstacle to their study. Compared to Seoul, Gyeonggi, and Incheon regions, students from Gangwon and other regions should pay special attention to some pre-classes to understand regular university lectures. In undergraduate education, a student's major aptitude is not a big problem. In order to change major, students need counseling about their major's aptitude only at the beginning semester. In order to get good grades, the achievement of the will to study is more important than the will to study itself. Professors should encourage students to review what they have learned in class after class and always assure students sincerity in their studies through the counseling process.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5755-5762
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• 2015

Background: Short-course preoperative radiation (SCRT) with delayed surgery was found to increase pathologic complete response (pCR) rates in several trials. However, there was no clear answer on whether SCRT or long-course chemo-radiotherapy (LCRT) is more effective. Therefore we conducted this meta-analysis to evaluate the safety and efficacy of SCRT versus LCRT, both with delayed surgery, for treatment of rectal cancer. Materials and Methods: The literature was searched from PubMed, EMBASE, Web of Science, Cochrane Library and clinicaltrials.gov up to November, 2014. Quality of the randomized controlled trials (RCTs) was evaluated according to the Cochrane's risk of bias tool of RCT. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was used to rate the level of evidence. Review Manager 5.3 was employed for statistical analysis. Pooled risk ratios (RRs) and 95% confidence intervals (CIs) were calculated. Results: Three RCTs, with a total of 357 rectal cancer patients, were included in this systematic review. Metaanalysis results demonstrated there were no significantly differences in sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate. Compared with SCRT, LCRT was associated with significant increase in the pCR rate [RR=0.49, 95%CI (0.31, 0.78), P=0.003]. Conclusions: In terms of sphincter preservation rate, local recurrence rate, grade 3~4 acute toxicity, R0 resection rate and downstaging rate, SCRT with delayed surgery is as effective as LCRT with delayed surgery for management of rectal cancer. LCRT significantly increased pCR rate compared with SCRT. Due to risk of bias and imprecision, further multi-center large sample RCTs were needed to confirm this conclusion.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2016년도 전력전자학술대회 논문집
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• pp.143-144
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• 2016

본 논문에서는 유도무기 및 항공기 탑재장비용 30W급 군사용 DC-DC 컨버터를 설계하며, 군사용 전원장치 규격과 기존 군사용 DC-DC 컨버터 제품의 성능을 분석하여 개발제품의 요구사양을 정립한다. 기존 산업용 컨버터와 군사용 컨버터의 설계 방식 차이점을 분석한 뒤 MIL 규격과 정량적 요구사양 만족 여부를 실험 및 공인인증기관 시험을 통해 검증한다.

• 한국기계가공학회지
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• 제21권7호
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• pp.34-42
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• 2022

Minimizing the backlash of gears and reducers is important for their proper and precise functioning. In this study, an automatic backlash measuring system was developed for the mass production and quality control of a military-grade reducer. The developed automatic backlash measurement system eliminates human error during the backlash measurement process. It also reduces the manufacturing time and digitizes the backlash number. The system was tested for an aircraft machine gun control reducer that required low-torque and high-precision conditions. The test results show that the torque range was 0.820-4.788 Nm. The maximum torque error is less than 0.231 N·m at 2.943 N·m, and 1.2 arcmin of the maximum backlash error with ± 0.3 arcmin of repeatability. The developed system satisfies all required conditions: torque of 1-3 Nm, torque accuracy within ± 0.5 N·m, and backlash accuracy of ± 3 arcmin.

• Journal of the Korean Data and Information Science Society
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• 제27권6호
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• pp.1525-1536
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• 2016

학군장교 (ROTC)는 대학에 재학 중인 우수 학생들을 선발하여 2년간 군사교육을 실시하고 졸업과 동시에 장교로 임관시켜 군의 초급 지휘자로 활용하는 제도로서 규모나 역할로 봤을 때 우리나라의 군과 사회에서 차지하는 비중이 매우 크다. 따라서 ROTC 출신 초급장교들의 리더십을 향상시켜 우리나라 군의 무형 전투력을 성장시키는 것이 매우 중요하다. 본 연구의 목적은 학군장교 양성교육 프로그램이 학군장교 리더십을 향상시키기 위해 적절한 교육을 제공하고 있는지 파악하고 개선방안을 제시하는 데 있다. 먼저 학군장교 교육 프로그램을 크게 세 분야로 나누어 1, 2차 설문조사를 실시한 뒤, 카이제곱 검정 (chi-square test), 분산분석 (ANOVA), 던컨의 다중검정 (Duncan's multiple range test) 등의 통계분석 방법들을 이용하여 교육프로그램에 직간접적으로 관련된 조사대상자들의 교육에 대한 실태 및 인식을 비교 분석한다. 또한 다중회귀분석 (multiple regression analysis)을 이용하여 학군후보생 리더십의 기본요소인 육군리더의 3대자질 형성에 영향을 미치는 세부요소들을 분석한다.