• Title/Summary/Keyword: Mild Condition

Search Result 483, Processing Time 0.025 seconds

Synthesis of Trifoliate Orange Extract Having Anti inflammation Activities (항염증 활성을 갖는 탱자 추출물 합성)

  • Kim, Duck-Sool;Roh, Eon-Joo
    • Journal of the Korean Applied Science and Technology
    • /
    • v.28 no.2
    • /
    • pp.196-202
    • /
    • 2011
  • Coumarin derivatives were shown to possess valuable pharmacological properties such as anticancer/anti carcinogenic, anti-inflammatory, anti helicobacter, anti genotoxic, neuroprotective and dietary effect. In this study, novel coumarin derivatives structurally related to 7-geranyloxycoumarin were effectively synthesised in good yields by $Cs_2CO_3$/acetonitrile in mild condition. The synthesis of geranyloxycoumarin derivatives in weak base($Na_2CO_3$, $K_2CO_3$, $Cs_2CO_3$ etc)/$CH_3CN$ at room temperature obtained in good yield. On the other hand, the reaction of geranyloxycoumarin formation in strong base(NaOH, KOH, CsOH etc)/$CH_3CN$ at reflux condition obtained in low yield.

Lymphocytic-Plasmacytic Enteritis (LPE) in Chinese Shar-Pei Dog (중국산 샤페이 개에서 발생한 림프구성-형질구성 장염의 발생예)

  • 박희명;오태호;황철용;한홍율;윤순식
    • Journal of Veterinary Clinics
    • /
    • v.15 no.1
    • /
    • pp.203-208
    • /
    • 1998
  • A two-year-old male Chinese Shar poi dog was admitted to the hospital because of chronic diarrhea. Abnormalities detected on physical examination were thickened intestinal loops and thin or cachexic body condition.4 complete blood count revealed a mild neutrophilia. The blood chemistry panel indicated no significant abnormalities. On proctoscopic examinations colonic mucosa was reddened and edematous. Numerous Iymphocytes, plasma cells and epithelial cells were observed in the cytologic examination of the rectal scraping.4 treatment was initiated with sulfasalazinei metronidazole and prednisolone and dietary management with rice and cottage cheese was performed simultaneously. Although antibiotic therapy and dietary management were donee the dog's condition deteriorated and died suddenly. Lymphocytic-plasmacytic enterocolitis was diagnosed by postmortem pathologic examination.

  • PDF

Severe Hypothermia Accompanying Acute Subdural Hemorrhage

  • Kim, Jung-Goan;Kim, Seok-Won
    • Journal of Korean Neurosurgical Society
    • /
    • v.39 no.3
    • /
    • pp.228-230
    • /
    • 2006
  • Hypothermia is relatively a common condition and most cases involve mild hypothermia. But severe hypothermia below $30^{\circ}C$ is medical an emergency condition. We report the case of a 41-year-old man who had been left in a manhole for more than 9 hours on a freezing cold water. He was transported to our emergency room in semicomatose state with a body temperature $26.5^{\circ}C$. The patient was warmed with active rewarming. After initial stabilization, the patient was taken for a brain computed tomography and found to have large fronto-temporo-parietal[FTP] subdural hemorrhage. The patient underwent an emergent decompressive craniectomy and hematoma evacuation. After surgery, he recovered to drowsy mentation and vital signs were stable.

Noise Diagram of an Automotive Turbo Charger and Its Applications (차량용 터보차져의 소음도표 작성 및 응용)

  • Lee, Hyeong-Il
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.20 no.5
    • /
    • pp.502-509
    • /
    • 2010
  • A test facility which can simultaneously measure turbocharger operating condition variables and vibro-acoustic emission in the situations that are quite similar to real internal combustion engine operating conditions has been introduced. Using this facility, a new method sweeping from full open throttle to deep surge region along constant speed curves can be utilized instead of the stationary method that has been traditionally used to obtain turbocharger compressor maps. Data covering an extensive range of the compressor performance map have been collected and analyzed. An experimental study is performed to define a noise diagram that correlates vibro-acoustic measurements to aerothermodynamic operating conditions. An instrumentation set in the facility allows the automatic definition of the operating point on the turbine and compressor map of the turbocharger. Also, radiated sound pressure and casing vibration data corresponding to the point are obtained by a microphone in the vicinity of the compressor casing and an accelerometer on the casing. The major source(s) of noise at specific operating point on the map can be easily identified with these maps. Also, acoustic characteristics of a given turbocharger at the vicinity of the surge as well as in the surge are also defined. Finally, the possibility to define mild surge region of a turbocharger using vibro-acoustic measurements is studied.

Evaluation of the Springback Characteristics for Automotive Steel Sheets by the S-Rail Forming Test (S-레일 시험을 통한 자동차용 판재의 스프링백 특성 평가)

  • Kwon, ln-Jae;Rim, Jae-Kyu;Kim, Hyung-Jong
    • Journal of Industrial Technology
    • /
    • v.21 no.B
    • /
    • pp.287-294
    • /
    • 2001
  • This study is aimed to evaluate the springback characteristics of automotive steel sheets through the S-rail forming test and to find the process condition under which springback can be reduced. Die set for the S-rail test has been made according to the dimension of the NUMISHEET '96 benchmark model. Experiment and finite element analysis have been performed on two kinds of automotive steel sheets: mild steel, SPCEN and high strength steel, SPRC. The test results show that the amount of springback is larger on the high strength steel SPRC than on the mild steel SPCEN, and decreases with increasing blank holding force as the case of material flow. And the reduction of friction has the effect of lowering the blank holding force in view of punch force and material flow. It is shown that the strain distribution over the whole specimen and along the specified sections calculated from the finite element analysis coincides with the measured data except local differences.

  • PDF

Numerical Analysis of Diffraction Using Parabolic Mild-Slope Equation (포물선형 완경사 방정식에 의한 회절현상의 수치해석)

  • Kim, Sang-Ug;Son, Min-Woo;Baek, Kyoung-Oh
    • Proceedings of the Korea Water Resources Association Conference
    • /
    • 2006.05a
    • /
    • pp.1914-1918
    • /
    • 2006
  • Recently, the importance of ocean becomes more serious. Thus, we need to construct port structures and instruments safely. Especially, we should understand the diffraction phenomenon of wave in order to construct breakwaters. To simulate diffraction of wave, parabolic mild slope equations are solved using FDM. A breakwater with an open part and an half infinite breakwater are selected for simulation. Diffraction of wave are simulated in the condition of wave angles of attack of $0^{\circ},\;30^{\circ}\;and\l;60^{\circ}$. Diffraction Coefficient and 1)Ampplitude are shown in graphics and compared with results of Penny & Price and Memos.

  • PDF

Atypical Coarctation in the Descending Thoracic Aorta: Treated by Bypass Graft (만성 비특이성 동맥염에 의한 비전형적 하행 흉대동맥 협착증: Bypass graft 를 시행한 1예)

  • Jang, Un-Ha;Yu, Hoe-Seong
    • Journal of Chest Surgery
    • /
    • v.11 no.1
    • /
    • pp.81-84
    • /
    • 1978
  • A 15 years Old girl was admitted with chief complaints of intermittent claudication of lower extremity, dizziness, and headache for 5 years. On admission, malignant hypertension was noted in the upper part of body [190-150/120-110] but femoral & dorsalis pedis pulse could not palpate. Once she had experienced C. V. A. due to hypertension of upper part, about years ago. On auscultation, systolic murmur was audible along the left sternal border. E.C.G. Showed left ventricular hypertrophy pattern, and others within normal limit. Retrograde aortography demonstrated diffuse narrowing of entire thoracic aorta with underdeveloped lower abdominal aorta [below the renal artery] & both common lilac artery, and rich collaterals, but normally visualized greater arteries in the aortic arch. On left posterolasteral thoracotomy, entire descending thoracic aorta revealed marked narrowing with mild perivascular adhesion, but no mediastinal pleura adhesion. These findings suggest as congenital type of atypical coarctation in the entire thoracic aorta with mild secondary change. But histopathology was showed the findings of chronic non-specific aortitis, later. Dacron by pass graft was performed with end to side anastomosis between graft and aortic wall. After operation, all her preoperative symptoms & signs were disappeared, and discharged with good general condition.

  • PDF

Friction and Wear at Dry Sliding Low Carbon Steel Surfaces Under Vacuum Conditions (진공분위기 내에서 건조마찰 미끄럼운동을 하는 저탄소강 표면의 마찰마모 특성)

  • 공호성;윤의성;권오관
    • Tribology and Lubricants
    • /
    • v.10 no.3
    • /
    • pp.29-38
    • /
    • 1994
  • The friction and wear of mild steel at dry sliding surfaces under different vacuum conditions have been investigated to understand the wear mechanisms. For the test, a ball-ondisk typed wear-rig has been built and implemented, allowing control of sliding speed, load and vacuum. Results show that, at a high sliding velocity, friction of low carbon steel (SS41) under a high vacuum is much higher than that of ambient condition and wear is much severer. It is due to lack of effective oxidation film formation on which steel surfaces could protect themselves against the severe wear. It has been shown, however, that there is a critical regime with contact conditions (at a low sliding velocity, a low load, and under a medium vacuum) at which effective, protective films of low carbon steel have been built on the surfaces in a friction process with a self-regulating way, resulting in both very low coefficients of friction (about 0.3) and mild wear. In order to investigate the protective films on steel surfaces, the worn surfaces and the wear debris have been experimentally analyzed with SEM, AES/SAM and XRD. A theoretical analysis of frictional heating at sliding surfaces, and an experimental analysis of the influence of oxidation wear under various vacuum conditions are described. The important variables on which self-formations of protective films at dry sliding surfaces depend, and the wear mechanisms are also investigated.

Chronic endometritis and infertility

  • Park, Hyun Jong;Kim, You Shin;Yoon, Tae Ki;Lee, Woo Sik
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.43 no.4
    • /
    • pp.185-192
    • /
    • 2016
  • Chronic endometritis (CE) is a condition involving the breakdown of the peaceful co-existence between microorganisms and the host immune system in the endometrium. A majority of CE cases produce no noticeable signs or mild symptoms, and the prevalence rate of CE has been found to be approximately 10%. Gynecologists and pathologists often do not focus much clinical attention on CE due to the time-consuming microscopic examinations necessary to diagnose CE, its mild clinical manifestations, and the benign nature of the disease. However, the relationship between CE and infertility-related conditions such as repeated implantation failure and recurrent miscarriage has recently emerged as an area of inquiry. In this study, we reviewed the literature on the pathophysiology of CE and how it may be associated with infertility, as well as the literature regarding the diagnosis and treatment of CE. In addition, we discuss the value of hysteroscopic procedures in the diagnosis and treatment of CE.

Bone Marrow Toxicity Caused by Estrogen Toxicity in a Yorkshire Terrier with Leydig Cell Tumor

  • Kim, Yoon-Hee;Ko, Kyu-Ryeon;No, Mi-Young;Kim, Jae-Hoon;Choi, Ul-Soo
    • Journal of Veterinary Clinics
    • /
    • v.36 no.2
    • /
    • pp.129-131
    • /
    • 2019
  • A 15-year-old intact Yorkshire terrier was presented with anorexia, lethargy, and a pale mucous membrane. A physical examination one year ago revealed right testis mass and subcutaneous petechia. Blood work revealed severe thrombocytopenia and mild anemia, and no abnormalities were found in serum chemistry or ultrasonography. The preoperative serum estrogen concentration was moderately elevated. The enlarged testis was surgically removed. A well-encapsulated mass composed of polyhedral or round with abundant eosinophilic cytoplasm containing fine granular or vacuolation were found in a histological examination of the removed tissue. The nuclei of tumor cells were round, and mitotic figures were low but neoplastic cells showed a mild invasive tendency to adjacent tissues with contained neoplastic cell emboli in one lymphatic lumen. A diagnosis of a malignant Leydig cell tumor was made. The patient recovered from surgery uneventfully, but his condition worsened despite repeated transfusions and supportive therapy, and he was euthanized according to the owner's decision. Leydig cell tumor should be included in estrogen toxicity associated with testicular mass.