• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.566-569
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• 2008

Recently, the biolistic process is emerging as an effective needle-free drug delivery technique to transfer adequate concentrations of pharmacologic agents to soft living tissues with minimum side effects. We have started developing an effective method for delivering drug coated particles using laser ablation. A thin metal foil with deposited micro-particles on one side is irradiated with laser beam on the opposite side so that a shock wave is generated. This shock wave travels through the foil and is reflected, which causes and instantaneous deformation of the foil. Due to such a sudden deformation, the micro-particles are ejected at a very high speed. Here we present the experimental results of direct and confined laser ablation, which correspond to the initial stage of the whole experiment.

• Journal of the Society of Naval Architects of Korea
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• v.32 no.1
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• pp.118-131
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• 1995

The shock fracture analysis for the structures of navy vessels subject to underwater explosions or of high speed vessels frequently subject to impact loads has been carried out in two steps such as the global or macro analysis and the fine or micro analysis. In the macro analysis, Doubly Asymptotic Approximation(DAA) has been applied. The three main failure modes of structure members subject to strong shock loading are late time fracture mode such as plastic large deformation mainly due to dynamic plastic buckling, and the early time fracture mode such as tensile tearing failure or transverse shear failure. In this paper, the tensile tearing failure mode is numerically analyzed for the micro analysis by calculating the dynamic stress intensity factor $K_I(t)$, which shows the relation between stress wave and crack propagation on the longitudinal stiffener of the model. Especially, in calculating this factor, the numerical caustic method developed from shadow optical method of caustic well known as experimental method is used. The fully submerged vessel is adopted for the macro analysis at first, of which the longitudinal stiffener, subject to early shock pressure time history calculated in macro analysis, is adopted for the micro analysis.

• Advances in Computational Design
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• v.1 no.4
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• pp.357-370
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• 2016

This paper aims to examine the dynamic response of a newly designed ultrasonic motor under half-sine shock impulses. Impact shock was applied to the motor along x, y or z axis respectively with different pulse widths to check the sensitivity of the motor to the shocks in different directions. Finite Element Analysis (FEA) with the ANSYS software was conducted to obtain the relative displacement of a key point of the motor. Numerical results show that the maximum relative displacement is of micro meter level and the maximum stress is five orders smaller than the Young's modulus of the piezo material, which proves the robustness of the motor.

• Structural Engineering and Mechanics
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• v.82 no.4
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• pp.459-467
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• 2022

We investigated the influence of variable thermal conductivity on waves propagating through the elastic medium. Infinitesimal deformation results in generation of thermal signal, and is analyzed by using dual phase lag heat (DPL) conduction model. The medium considered is homogenous, isotropic and bounded by thermal shock. The elastic waves propagating through the medium are considered to be harmonic in nature, and expressions for the physical variables are obtained accordingly. Analytically, we obtained the expressions for displacement components, temperature, micro-temperature component and stresses. The theoretical results obtained are computed graphically for the particular medium by using MATLAB.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2007.11a
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• pp.285-288
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• 2007

Numerical study of the influence of the boundary layer of micro-supersonic jet impinging on a flat plate with a hole was performed, to investigate the role of gas jet to eject melted materials from the cut zone in the laser machining. The detailed shock structures and the information of the mass flow rate through the hole were compared to the results of the previous study, in which the effects of boundary layer inside nozzle was not accounted. It was found that the boundary layer inside the micro- nozzle introduced stronger Mach disc over the machining zone, and thus that the mass flow rate through the hole decreased.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.36 no.6
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• pp.587-593
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• 2008

Transdermal and topical drug delivery with minimal tissue damage has been an area of vigorous research for years. Our research team has initiated the development of an effective method for delivering drug particles across the skin (transdermal) for systemic circulation, and to localized (topical) areas. The device consists of a laser ablation based micro-particle acceleration system that can be integrated with endoscopic surgical techniques. We have successfully delivered 3μm size cobalt particles into gelatin models that represent soft tissue with remarkable penetration depth.

• Journal of the Korean Society for Nondestructive Testing
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• v.29 no.5
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• pp.450-457
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• 2009

Periodical thermal shock can introduce defects in thermal barrier coating made by layers of CoNiCrAlY bond coating(BC) and $ZrO_2-8wt%Y_2O_3$ ceramic top coating(TC) on Inconel-738 substrate using plasma spraying. Thermal shock test is performed by severe condition that is to heat until $1000^{\circ}C$ and cool until $20^{\circ}C$. As the number of cycle is increased, the fatigue by thermal shock is also increased. After test, the micro-structures and mechanical characteristics of thermal barrier coating were investigated by SEM, XRD. The TGO layer of $Al_2O_3$ is formed between BC and TC by periodical thermal shock test, and its change in thickness is inspected by eddy current test(ECT). By ECT test, it is shown that TGO and micro-crack can be detected and it is possible to predict the life of thermal barrier coating.

• Design & Manufacturing
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• v.14 no.3
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• pp.57-62
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• 2020

In the drug delivery system industry, the technology with even split injection becomes important for maximizing efficiency and minimizing the side effects. In conventional drug delivery system, infection can occur due to pain and splashing. Also, various applications are impossible due to disposable use, and it is the reason to avoid to use this system because of the complexity of the driving method. Therefore, in this study, a painless drug delivery device is developed for non-pain with electrical insulation breakdown method. Finite elements analysis was used to evaluate the ejection characteristics of drugs according to the shape of the micro ejection nozzle. The effect of the number of holes in the micro nozzle, the length of the nozzle and the inner shape of the nozzle on the drug discharge characteristics were analyzed.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.7 no.1
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• pp.29-34
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• 2009

Purpose : This study aims to investigate into the change in muscle power, pain and muscle tension upon application of extracorporeal shock wave therapy (ESWT) and ultrasound (US) at trigger point (TrP) of the Scapular inter angle. Methods : In total of 24 human subjects that experience pain upon stimulation at the scapular inter angle were recruited. They were divided into three groups: control, ESWT and US group. Each group was subjected to appropriate stimulation three times per week for four weeks except the control group which had no restrictions in lifestyle. The ESWT group was subjected to Extracorporeal Shock Wave Therapy with a 2 $cm^2$ head, 20 times at speed of application of 60 pulses/min and depth of intrusion of 25 mm Whereas the US group was subject to Ultra sound therapy with 1$cm^2$ head, 1 MHz in frequency, 1.5 W/$cm^2$ of strength with five minutes of continuous application. Measurements were performed immediately prior to and at the end of the experiment. Results : There was no statistical significance in the change in muscle tension and muscle power as well as the difference between both groups before and after the experiment. VAS and VRS, all of which indicates changes in pain level, had statistically significant differences between them in pretest posttest comparisons. However, ESWT was superior to US in terms of decreasing muscle tension and pain while increasing muscle power. Conclusion : This study has made it evident that ESWT is far more reasonable to apply to TrP.

• Journal of Korean Society of Transportation
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• v.23 no.1
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• pp.67-80
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• 2005

In this paper, the primary objective of the research are to review the methods currently avaliable for estimating the delay incurred by vehicles at signalized intersections. The paper compares the delay estimates from a deterministic queueing model, a model based on shock wave theory , the steady-state Webster model, the queue-based models defined in the 1994 and 2001 version of the High way Capacity Manual, in addition to the delays estimated from the TRANSYT-7F macroscopic simulation and NETSIM microscopic simulation. More especially, this paper is to compare the delay estimates obtained using macroscopic and microscopic simulation tools against state-of-the practice analytical models that are derived from deterministic queueing and shock wave analysis theory. The results of the comparisons indicate that all delay models produce relatively similar results for signalized intersections with low traffic demand, but that increasing differences occur as the traffic demand approaches saturation. In particular, when the TRANSYT-7F and NETSIM are compared, it is highly differences as approach for traffic condition to over-saturation. Also, the NETSIM microscopic simulation is the lowest estimates among the various models.