• Animal Bioscience
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• v.36 no.4
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• pp.555-569
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• 2023

Objective: The objective of this study was to investigate the effects of N⁶-Methyladenosine modification-circRNA-zinc finger protein 638 (m⁶A-circRNA-ZNF638) on the induced activation of secondary hair follicle (SHF) stem cells with its potential mechanisms in cashmere goats. Methods: The m⁶A modification of ZNF638 was analyzed using methylation immunoprecipitation with real-time quantitative polymerase chain reaction technique in SHF stem cells. The effects of circRNA-ZNF638 on the induced activation of SHF stem cells in m⁶A dependence were evaluated through the overexpression of circRNA-ZNF638/its m⁶A-deficient mutants in circRNA-ZNF638 knockdown SHF stem cells. The competitive binding of miR-361-5p to circRNA-ZNF638/Wnt5a 3'- untranslated region was analyzed through Dual-luciferase reporter assay. Results: The m⁶A-circRNA-ZNF638 had significantly higher transcription at anagen SHF bulge of cashmere goats compared with that at telogen, as well as it positively regulated the induced activation of SHF-stem cells in cashmere goats. Mechanismly, m⁶A-circRNA-ZNF638 sponged miR-361-5p to heighten the transcriptional expression of Wnt5a gene in SHF-stem cells. We further demonstrated that the internal m⁶A modification within circRNA-ZNF638 is required for mediating the miR-361-5p/Wnt5a pathway to regulate the induced activation of SHF stem cells through an introducing of m⁶A-deficient mutant of circRNA-ZNF638. Conclusion: The circRNA-ZNF638 contributes the proper induced activation of SHF-stem cells in cashmere goats in m⁶A-dependent manner through miR-361-5p/Wnt5a axis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.1
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• pp.40-48
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• 2017

This study investigated the relationship among emotional regulation, coping strategies and satisfaction in clinical practice, and examined factors influencing satisfaction with clinical practice in nursing students. Data were collected through structured questionnaires from May 1 to June 30, 2016. The study participants were 201 third and fourth year nursing students at four departments of nursing located in B and K metropolitan city. Data were analyzed using t-test, ANOVA, Scheffe's test, Pearson's correlation coefficients and stepwise multiple regression with SPSS WIN v 20.0. The mean emotional regulation score was $3.73{\pm}0.48$, active coping was $2.79{\pm}0.33$, passive coping was $2.53{\pm}0.36$, and practice satisfaction was $3.58{\pm}0.46$. Statistically significant relationships were noted between emotional regulation and satisfaction with clinical practice (r=.391, p<.001), between active coping and satisfaction with clinical practice (r=.361, p<.001), between passive coping and satisfaction with clinical practice (r=.276, p<.001). Factors influencing satisfaction with clinical practice were satisfaction with the nursing major (${\beta}=-.322$, p<.001) and emotional regulation (${\beta}=.232$, p<.001). These factors explained 28.1% of variance in participant's satisfaction with clinical practice. In conclusion, effective nursing educational programs need to be developed to enhance satisfaction with clinical practice and to foster positive emotional regulation in nursing students.

• Journal of Korean Biological Nursing Science
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• v.19 no.3
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• pp.123-130
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• 2017

Purpose: This study aimed to identify factors influencing intra-operative core body temperature (CBT), and to develop a predictive model for intra-operative CBT in laparoscopic abdominal surgery. Methods: The prospective observational study involved 161 subjects, whose age, weight, and height were collected. The basal pre-operative CBT, pre-operative blood pressure, and heartbeat were measured. CBT was measured 1 hour and 2 hours after pneumoperitoneum. Results: Explanatory factors of intra-operative hypothermia (< $36^{\circ}C$) were weight (${\beta}=.361$, p< .001) and pre-operative CBT (${\beta}=.280$, p= .001) 1 hour after pneumoperitoneum (Adjusted $R^2=.198$, F= 7.56, p< .001). Weight was (${\beta}=.423$, p< .001) and pre-operative CBT was (${\beta}=.206$, p= .011) 2 hours after pneumoperitoneum (Adjusted $R^2=.177$, F= 5.93, p< .001). The researchers developed a predictive model for intra-operative CBT ($^{\circ}C$) by observing intra-operative CBT, body weight, and pre-operative CBT. The predictive model revealed that intra-operative CBT was positively correlated with body weight and pre-operative CBT. Conclusion: Influence of weight on intra-operative hypothermia increased over time from 1 hour to 2 hours after pneumoperitoneum, whereas influence of pre-operative CBT on intraoperative hypothermia decreased over time from 1 hour to 2 hours after pneumoperitoneum. The research recommends pre-warming for laparoscopic surgical patients to guard against intra-operative hypothermia.

• Korean Journal of Community Nutrition
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• v.25 no.5
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• pp.361-373
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• 2020

Objectives: The purpose of this study was to investigate the relationship between stress levels and eating habits in adolescents. Methods: A total of 453 male and female high school students were surveyed to ascertain their stress levels, Nutrition Quotients for Korean Adolescents (NQ-A), and stress-related eating behavior. Results: The average age of the subjects was 18 and they were mostly from nuclear families. Their average daily conversation time with their parents was between 10 to 30 minutes. The average sleep time for female students was observed to be less than that of male students. The satisfaction level of academic achievement of female students was significantly lower than that of the male students (P < 0.001). The average stress level score for female students was 2.7 out of 5, which was significantly higher than the male student's score of 2.4 (P < 0.001). The eating speed of male students was related to stress levels. Both male and female students ate more and craved spicy food when under stress. All male and female students had significantly ascending NQ-A scores rising in the order of stress from 'low level' to 'medium level', to 'high level' (P < 0.001). There was a significant negative correlation between the stress score and the NQ-A score adjusted for general characteristics (r = -0.29, P < 0.001). Conclusions: Since stress and NQ-A were negatively correlated in high school students, higher stress levels can be associated with irregular eating habits and negative eating behavior. Therefore, stress management and nutrition education focusing on stress status are needed for adolescents.

• Journal of Digital Convergence
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• v.18 no.6
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• pp.353-361
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• 2020

The aim of this study was to identify the factors related to clinical practice stress in nursing college students. The participants comprised 160 students in a nursing college. Data collection was conducted from December 1, 2019 to December 15, 2019. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient and a multiple regression analysis. The average score for clinical practice stress was 3.19 out of a maximum of 5. clinical practice stress had a statistically significant relationship with self-esteem(r=.22, p=.005), nursing professionalism(r=-.26, p=.001) and cognitive emotion control strategy(r=.38, p<.001). The factors affecting clinical practice stress were maladaptive cognitive emotion control strategy(β=.46, p<.001), nursing professionalism(β=-.20, <.001), grade(β=.20, p=.002), motivation for nursing choice(β=-.15, p=.019); the explanatory power of the model was 35.5%. Therefore, in order to reduce the stress on clinical practice, it is necessary to develop a program that can lower the maladaptive cognitive emotion control strategy along with improving the nursing professionalism in stress situations.

• Research in Community and Public Health Nursing
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• v.11 no.1
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• pp.158-171
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• 2000

The elderly population will increase from 5.8% in 1996 to 12.5% in 2020. The related problems of health will also become a very important issue in the future. Therefore. it is important to address the problems of geriatic nursing and geriatic health. The purpose of this study was to examine the relationship among self-efficacy, social support and depression of the poor elderly. The subjects of this study were 42 poor elderly in Tae Jeon city. The data were analyzed by the SPSSWIN computer program and include AONVA. Pearson Correlation, frequency analysis. The Cronbach Alpha of self-efficacy tools was .8297, social support tools was .9187 and depression tools was .8887. The data were collected through personal interviews using a questionnaire from September 27 to October 23. 1999. The conclusion of this study are summarized as follows: 1. There were mean scores for self-efficacy at $55.92{\pm}11.84$ for social support $86.00{\pm}18.43$ and for depression $60.31{\pm}15.61$. 2. There was a significant positive correlation between self-efficacy and social support(r= .361. p<.05) in the poor elderly. There was a significant negative correlation between social support and depression(r= -.640, p<,01), self-efficacy and depression(r= -.182) in the poor elderly. 3. In a significant test in the general characters of the subjects and in the higher social support level. we obtained the following results: living with partner is. have son is. living family members is. the higher economic level is. 4. In a significant test in the general characters of the subjects and in the lower depression level, we can obtained the following results: The old man is. living with partner is. living family members is. the higher economic level is, the higher health level is.

• Journal of Korean society of Dental Hygiene
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• v.9 no.2
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• pp.73-88
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• 2009

The purpose of the study was to provide the basic for the prevention of infection control by analyzing the level of recognition and practice of dental hygiene students. It is important for dental clinic staffs to know and practice infection control measures in favor of effective infection control. Thus, this study conducted an one-month questionnaire survey (during October 2008) for dental hygiene students who ever experienced in 16-week clinical practice, and analyzed total 206 questionnaire forms as collected from them, so that it could determine potential associations between their recognition and practice of infection control and thereby suggest an efficient solution for infection control in dental hygiene. 1. It was found that our students' recognition about infection control averaged $4.49{\pm}.58$ points on the whole, and they were best aware of instrumental disinfection and sterilization among other measures, which was followed by hand washing, extirpation control, post-sterilization management, personal protective outfit and instrumental surface maintenance respectively. 2. It was found that our students' practice of infection control averaged $3.85{\pm}.57$ points on the whole, and they practiced hand washing most actively among other measures, which was followed by extirpation control, post-sterilization management, instrumental disinfection and sterilization, personal protective outfit and instrumental surface maintenance respectively. 3. It was found that our students scored higher mean points in recognition about every measure of infection control than those in practice (t=15.676, p=0.000). Particularly, it was notable that there were significant differences between their mean points in recognition and practice of some infection control measures, such as instrumental surface maintenance (t=15.361, p=0.000), personal protective outfit (t=15.245, p=0.000) and instrumental disinfection and sterilization (t=11.169, p=0.000). But there was least significant difference between mean points in recognition and practice of hand washing (t=5.460, p=0.000). 4. For potential associations between recognition and practice of infection control, it was found that higher recognition was in significantly positive associations with higher practice in every measure of infection control (r=.478, p=.000), such as extirpation control (r=.630, p=.000), instrumental disinfection and sterilization (r=.477, p=.000) and post-sterilization management (r=.433, p=.000). 5. It was found that there were differences in our students' recognition depending upon availability of infection control guideline (t=4.587, p=.011), and there were significant differences in practice depending on necessity of infection control education on a statistical basis (t=2.229, p=.027). Overall, it is found that our dental hygiene students are very likely to practice hand washing and extirpation control, because both of these measures are relatively easy to practice or are considered legally binding.

• Journal of Digital Convergence
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• v.16 no.5
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• pp.361-372
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• 2018

The purpose of this study was to develop an assessment scale for healthy aging of middle aged women. The data were collected from 385 middle aged women in two large cities in Korea. The development processes of the scale were followed: Development of preliminary items; Verification of content validity and reliability; Factor analysis and criterion validity of final items. Results: Factor analysis resulted in the creation of the final scale, which consisted of 38 items that were grouped into 9 factors: self achievement, physical change adaptation, psychological change adaptation, interpersonal relationships, menopausal symptom adaptation, economic stability, physical health, social support, social change adaptation. The explanatory variance was 64.03%. The reliability of the scale was Cronbach's ${\alpha}=.90$. Correlation of the scale with healthy aging and depression, established its construct and concurrent validity was r=-.69, p<.001. The scale was confirmed to have a relatively high validity and reliability. The findings of the study can be useful as a measurement to evaluate healthy aging of middle aged women. Future researches with the scale will be helpful for basic data for the program development to support healthy aging of middle aged women.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.18 no.2
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• pp.100-107
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• 2015

Purpose: We investigated the iron status of very low birth weight infants receiving multiple erythrocyte transfusions during hospitalization in the neonatal intensive care unit (NICU). Methods: We enrolled 46 very low birth weight infants who were admitted to the Kyungpook National University Hospital between January 2012 and December 2013. Serum ferritin was measured on their first day of life and weekly thereafter. We collected individual data of the frequency and volume of erythrocyte transfusion and the amount of iron intake. Results: A total of 38 (82.6%) of very low birth weight infants received a mean volume of $99.3{\pm}93.5mL$ of erythrocyte transfusions in NICU. The minimum and maximum serum ferritin levels during hospitalization were $146.2{\pm}114.9ng/mL$ and $456.7{\pm}361.9ng/mL$, respectively. The total volume of erythrocyte transfusion was not correlated to maximum serum ferritin concentrations after controlling for the amount of iron intake (r=0.012, p=0.945). Non-transfused infants took significantly higher iron intake compared to infants receiving ${\geq}100mL/kg$ erythrocyte transfusion (p<0.001). Minimum and maximum serum ferritin levels of non-transfused infants were higher than those of infants receiving <100 mL/kg erythrocyte transfusions (p=0.026 and p=0.022, respectively). Infants with morbidity including bronchopulmonary dysplasia or retinopathy of prematurity received a significantly higher volume of erythrocyte transfusions compared to infants without morbidity (p<0.001). Conclusion: Very low birth weight infants undergoing multiply erythrocyte transfusions had excessive iron stores and non-transfused infants also might had a risk of iron overload during hospitalization in the NICU.