• Title/Summary/Keyword: Methylcellulose solution

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Characteristics of Silver Nanow ire Solution and Film Depending on Hydroxypropyl Methylcellulose Adhesion Promoter Addition (Hydroxypropyl methylcellulose 접착력 증진제 첨가에 따른 은 나노와이어 용액 및 필름의 특성 변화)

  • Seungju Kang;Kim
    • Journal of Adhesion and Interface
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    • v.24 no.2
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    • pp.54-59
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    • 2023
  • Silver nanowire-based transparent electrodes are very attractive as a next-generation flexible and transparent electrode that can replace ITO-based flexible electrodes because they have excellent conductivity, transmittance and mechanical flexibility. However, weak understanding of the silver nanowire solution for the fabrication of silver nanowire-based transparent electrodes often cause abnormal operation of the electrical device or peeling problem of the electrode films when applied to electronic devices. Here, we studied a Hydroxypropyl Methylcellulose (HPMC) adhesion promoter, which is one of the additives for silver nanowire solution, to improve the understanding of silver nanowire solution. In detail, it is characterized how the HPMC changes the properties of silver nanowire solution and silver nanowire film, which is fabricated with silver nanowire solution including the HPMC adhesion promoter. As the characteristics of solution, polar surface tension and dispersive surface tension were measured. As the film characteristics, surface energy, surface morphology, silver nanowire density, and sheet resistance were analyzed.

Influence of Methylcellulose on Properties of Wheat Gliadin Film Cast from Aqueous Ethanol

  • Song, Yihu;Li, Lingfang;Zheng, Qiang
    • Food Science and Biotechnology
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    • v.18 no.4
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    • pp.910-916
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    • 2009
  • Present work was focused on the influence of methylcellulose (MC) on steady rheology of wheat gliadin solution and the properties of glycerol plasticized gliadin films. The presence of MC below 0.99 wt% improved viscosity and flow activation energy of the 10 wt% gliadin solution significantly. In the casting films containing 0.2 g glycerol/g dry protein, the MC component aggregated in the gliadin matrix. The blend films containing less than 7.7 wt% MC exhibited higher Young's modulus (E) and tensile strength (${\sigma}_b$) and lower elongation at break (${\epsilon}_b$) in comparison with the pure gliadin film, which was related to the intermolecular interaction between MC and gliadins, the brittle fracture of the aggregated MC component, and the increase in glass transition temperature ($T_g$) of the gliadin phase. Increasing MC content led to a slight increase in water vapor permeability (WVP) without significant influence on the moisture absorption (MA).

Modified Upper Gastrointestinal Study Using Methylcellulose After Administration of Barium Suspension : Comparison with Conventional Series (바륨 현탁액과 메틸셀룰로스(Methylcellulose)를 사용한 변형 상부위장관조영술 :전통적 바륨조영술과의 비교)

  • 이기창;최민철;서민호;정주현;윤정희
    • Journal of Veterinary Clinics
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    • v.17 no.2
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    • pp.411-415
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    • 2000
  • For comparison with conventional barium-gastrointestinal study, modified method using barium and methylcellulose was performed in 16 normal dogs (4-8 kg) divided into two groups. The group 1 received 8ml/kg of 40% w/v barium suspension only, and group 2 had taken 15 ml/kg of 0.6% w/v methylcellulose after administration 4 ml/kg of 40% w/v barium suspension by feeding tube. The barium suspension was prepared mixing full strength-barium suspension with water and methylcellulose solution was produced by blending methylcellulose sterilized water Sequential radiographs, lateral and ventrodorsal projections were obtained at 5 minute, 20 minute,40 minute. 60 minute and every 30 minutes thereafter, until the contrast is seen in the large intestine Inage qual- ity was rated by three veterinary radiologists as " poor" " fair ". "good", or "excellent" We analyzed the relationship between image quality,, transit time. Between two techniques, the modified method with 4ml of 40% w/v barium suspension and 15 ml of 0.6% w/v methylcellulose showed much better image quality ["excellent" result in 7 of the 8 subjects (88%)] and shorter transit time (107 minutes) toe the cecum. In addition, the best image quality was obtained at 20 and 40 minutes after admin-istration of contrast agent. It call be concluded the modified gastrointestinal study using methylcel-lulose after administration of barium suspension was a simple technique and easily improved the image quality and diagnostic accuracy of gstrointestinal disorders in small animal.racy of gstrointestinal disorders in small animal.

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Toxic effects of methylcellulose solution on the liver, spleen and kidney in the Sprague-Dawley(SD) rats following repeated oral or intravenous administration (Methylcellulose의 경구 및 정맥내 반복 투여가 SD랫드의 간장, 비장 및 신장에 미치는 독성학적인 영향)

  • Song, Si-whan;Kang, Boo-hyun;Han, Sang-seop;Roh, Jung-koo;Lee, Chang-eup
    • Korean Journal of Veterinary Research
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    • v.36 no.1
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    • pp.221-233
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    • 1996
  • This experiment was carried out to study the toxic effect of solublized methylcellulose (MC). Sprague-Dawley rats were dosed with 1%(w/v) MC in 0.9% saline by gavage at a dose of 10ml/kg b.w/day or by intravenous injection at a dose of 5ml/kg b.w/day for 28 days. Clinical signs were observed once a day. Body weights, water and food consumptions were measured and urinalysis was performed several times during the experiment. Rats were sacrificed on days 3, 7, 15 and 28 for hematology, blood chemistry, organ weights and histopathology. The relative weight of the spleen and foamy cells of the spleen were increased in the gavage group. Body weight gain, food consumptions, the values of RBC, Hb, MCH, Hct, serum proteins, glucose, bilirubin, AST, and ALP were decreased in I.V. treatment group. On the other hand, water consumptions, the values of serum cholesterol, creatinine, and BUN were increased. Microscopic findings were granulomas, distended sinusoids, and hypertrophy of Kupffer cells with vacuoles in the liver. Spleen exhibited granuloma, increased extramedullary hematopoiesis, and congestion. Kidney exhibited foamy cells in the glomeruli, distension of the tubules. The findings appeared more severe when the treatment was extended. In conclusion, MC solution is not a safe vehicle for intravenous administration because of the toxic effects on the liver, kidney and spleen. In addition, a long-term and large dosage of oral administration of MC appears to be unsafe also and needs to be investigated further.

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Studies on the Miscibility of Methylcellulose/Chitosan Blends by Thermogravimetric Analysis and Thermodynamic Mechanical Analysis (열분석기기를 이용한 메틸셀룰로오스/키토산 블랜드의 상용성에 관한 연구)

  • Park, Jun-Seo;Shin, Ki-Ho
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.8 no.2
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    • pp.18-26
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    • 2002
  • Films of methylcellulose(MC), chitosan and their blends were prepared using water and acid solution as a solvent. The transition behavior and miscibility of polymers and their blends were characterized by dynamic mechanical analysis(DMA) and thermogravimetric analysis(TGA). The DMA analysis of PEG400/MC blends has shown that PEG400 was compatible with MC and was effective plasticizer since the curves of $tan{\delta}$ against temperature exhibited single peak, corresponding to single glass transition temperature, which were displaced to lower values with increasing PEG400 content. Results of DMA analysis and TGA analysis of MC/chitosan blends indicate that there are some miscibility between MC and chitosan in the blends, attributed to the similarities between two polysaccharides and interactions of two polymers in the blends. The inclusion of PEG400 in the blends increase the miscibility between two components in the blends.

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The Effects of Coating Treatments on Enteric Coating of the Soft Capsules Containing Omega-3 Fatty Acids (오메가-3 연질캡슐의 코팅 조건에 따른 장용성 코팅품질에 미치는 영향)

  • Ko, Won-Hwa;Hong, Jun-Kee;Lee, Sung-Wan;Cha, Ja-Hyun;Cha, Jae-Uk;Baek, Hyon-Ho;Park, Hyun-Jin
    • Korean Journal of Food Science and Technology
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    • v.44 no.2
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    • pp.168-172
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    • 2012
  • This article presents an evaluation of the effects of coating conditions on the enteric coating quality of soft gelatin capsules containing Omega-3 fatty acids. Three conditions were controlled: concentration of hydroxypropyl methylcellulose phthalate (6, 8, and 10 wt% in solution), temperature of the inlet air (32, 35, and $38^{\circ}C$), and the coating solution feed rate (7.5, 11.25, and 15.0 g/min). The transparency of the enteric coated soft gelatin capsules was evaluated by measuring the degree of whiteness of the surface using a spectrophotometer. Results showed that the most important parameter in the enteric coating process was the coating solution feed rate. As the coating solution feed rate decreased and inlet air temperature increased, the degree of whiteness of coating surfaces decreased. We also evaluated the disintegration properties of the enteric coated capsules in accordance with the Korea Health Functional Food Code.

The Mitigation of Bitterness of Zipeprol Solution (Zipeprol 내용액제의 고미교정에 관한 연구)

  • 김종국;최한곤
    • YAKHAK HOEJI
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    • v.31 no.1
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    • pp.42-44
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    • 1987
  • Ziperol, anti-tussive, is considerably bitter. Therefore, it is necessary to mitigate the bitterness in ziperol syrup for children. In this experiment, it was attempted to mitigate the bitterness of zipeprol by means of polymers such as $\beta$-cyclodextrin, arabic gum, HPMC(hydroxypropyl methylcellulose), PEG 2000(polyethyleneglycol 2000), PVP(polyvinylpyrrolidone). Caffeine was used as the reference standard of bitterness. In the result of this experiment, $\beta$-cyclodextrin, would mitigate the bitterness of zipeprol more largely than any other polymers. Arabic gum was the second choice which would mitigate the bitterness of zipeprol.

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Influences of Clotrimazole on the Blood Cholesterol and HDL-Cholesterol level in Rats (흰쥐의 혈중 콜레스테롤 및 HDL-콜레스테롤 함량에 미치는 Clotrimazole의 영향에 관한 연구)

  • 김성오;이명렬
    • Journal of environmental and Sanitary engineering
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    • v.12 no.3
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    • pp.87-94
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    • 1997
  • Influences of clotrimazole on the blood cholesterol and HDL-cholesterol level were studied in rats. Rats were provided food and water ad libitum and clotrimazole and methylcellulose were gavaged for 6 days. Clotrimazole was suspended in 1% methylcellulose solution as and administered at concentration 20mg/Kg, 40mg/Kg, 60mg/Kg. Body weight gain and liver weight/body weight ratio, serum cholesterol level, serum HDL-cholesterol level, serum triglyceride level, the activity of cytochrome p450 and erythromycin demethylase were determined at 6th day. Clotrimazole decreased the body weight gain a little as compared with control group and did not show any influence on liver weight/body weight ratio. Clotrimazole increased the serum HDL-cholesterol and serum triglyceride level significantly. Clotrimazole increased the microsomal cytochrome P450 significantly and increased the erythromycin demethylase (cytochrome P450 IIIA) significantly too. It might be conclued that clotrimazole showed a little influence on body weight and increased the serum lipid, especially HDL-cholesterol level. It also increased microsomal cytochrome P450 IIIA significantly. It might be concluded that clotrimazole showed a corelative influence between HDL-cholesterol and cytochrome P450 IIIA. In these results clotrimazole can be used as an anti-atherosclerotic agent by increasing the HDL-cholesterol but it is necessary that cloreimazole will show any adverse or side action on body or not.

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Preparation of Hydroxypropyl Methyl Cellulose with Controlled Solubility Rate by Surface Treatment Reaction (표면처리반응에 의한 용해속도조절용 Hydroxypropyl Methyl Cellulose의 제조)

  • Lee, Moo-Jin;Shin, Young-Jo
    • Applied Chemistry for Engineering
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    • v.10 no.4
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    • pp.581-585
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    • 1999
  • The surface treated hydroxypropyl methylcellulose(HPMC) which could adjust the soluble time was synthesized when 40 wt % glyoxal solution and $KH_2PO_4$ were sprayed and reacted. And also, the solution dynamic at different ratios of two adding agents were identified If the surface of HPMC was treated with only glyoxal, the dispersion characteristics at different ratios of two adding agents were identified If the surface of HPMC was treated with only glyoxal, the dispersion was observed in the neutral solution and the viscosity was increased after directly dissolved as the solution become alkali condition. But the fine-powder type of HPMC which reacted with glyoxal and $KH_2PO_4$ was dispersed regardless of pH of solution and observed that it was dissolved and its viscosity increased after elapsing some time. With increasing amount of glyoxal and $KH_2PO_4$, the soluble time was delayed. The reaction condition was about 60 min at $75{\sim}85^{\circ}C$. Especially, the removal process of organic solvent after reaction was not required due to reaction under water solution without organic during glyoxal and $KH_2PO_4$ treatment. And also, the HPMC which could adjust the soluble rate in water or organic solvent by changing the degree of substitution of HPMC was synthesized.

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The Effect of Temperature and Concentration of Setting Solution on the Rheological Properties of Injectable Calcium Phosphate (경화액의 농도와 온도가 인산칼슘시멘트의 유변학적 성질에 미치는 영향에 관한 연구)

  • Yoo, Hyun-Mi;Chang, Seok-Woo;Park, Dong-Sung
    • Journal of Dental Rehabilitation and Applied Science
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    • v.25 no.1
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    • pp.73-82
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    • 2009
  • Injectable calcium phosphate cement (CPC) has been used as bone substitute successfully due to good biocompatibility and osteoconductivity. One of the important mechanical characteristics of CPC is flowablility, which can be evaluated by measuring rheological parameters. However, there have been few studies that measured rheological properties of CPC. The purpose of this study was to evaluate the effects of temperature and concentrations of 2 kinds of setting solutions, hydroxyprophyl methylcellulose (HPMC) and polyacrylic acid (PAA), on rheological properties of CPC. The CPC used was dicalcium phosphate dihydrate (DCPD). Rheological properties of CPC paste were measured using rheometer. The effect of concentrations of each solution (2% and 1% HPMC and 35% and 17.5% PAA) was evaluated. The effect of temperature ($25^{\circ}C$ and $37^{\circ}C$) on the rheological properties of CPC was also investigated. The statistical analysis was carried out with Mann-whitney test with Bonferronis collection. CPC with both setting solutions showed shear thinning behavior. Higher concentrations of setting solution (2% HPMC and 35% PAA) produced significantly higher viscosity than lower concentrations of setting solution (1% HPMC and 17.5% PAA). CPC with HPMC showed significantly higher viscosity at $37^{\circ}C$ that at $25^{\circ}C$. CPC with PAA showed lower viscosity at $37^{\circ}C$ than at $25^{\circ}C$, although the difference was not statistically significant. The results showed that CPC with HPMC or PAA solutions are pseudoplastic and the concentrations of setting solutions and temperature may have an effect on the rheological properties of CPC paste. These results showed that the flowability of injectable CPC could be improved by use of increasing frequency of oscillation. In clinical practice, the use of ultrasonic vibration would be helpful in application of injectable CPC. CPC with HPMC could be more easily applicated at $25^{\circ}C$ than $37^{\circ}C$. The use of lower concentrations of HPMC and PAA solution would be beneficial in terms of flowability.