• Journal of Society of Preventive Korean Medicine
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• v.3 no.1
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• pp.35-54
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• 1999

This thesis shows about the meaning of treatment rate increasing, the current treated level and the reason of low treatment rate and increasing methods. 1. Treatment rate incresing means high treat level within short time, keeping treatment effect for a long time as well as raising treatment rate. 2. The current by diseases each others completed treatment rate of oriental medicine is 14.0% to 89.7%$(mean:\;{\pm}40.0%)$. Therefore the rate is show too low. 3. The reasons of low treatment rate; low academic level of oriental, academic limitation, clinic and prevention problem of oriental medicine, lack of medical approch suitable for current diseases and symptoms, mostly incurrable diseases using oriental medicine, lack of preventive education, disappropriate medical service and nonspecialty of the treatment, etc. 4. The next methods for incresing the treatment rate must be improved; such as accurate establishment of process that diagnosis symptoms and treats them, system research of microdiagnosis, positive treatment with medicine and nonmedicine method at the same time, appropriate subdivision and actualization of clinical basic research, research of dose and response, diversity of treatment methods and forms, development of treatment service and prevention based on health level, enormous change as cure medicine and opening-up of new disease field, specialization of medical examination, reinforcement of public medical part and herbal drugs use with same origin, mental and pysical stability of patients, accurate extract and oral drinking ways, etc.

• Journal of Microbiology and Biotechnology
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• v.21 no.6
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• pp.604-612
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• 2011

Beauveria bassiana SFB-205 supernatant can effectively control cotton aphid populations, which is closely associated with its chitinase activity. The present work extends to optimizing a culture medium to produce more efficacious supernatant in flask conditions, followed by scale-up in 7 L, 300 L and 1.2 KL fermentors with the parameter of chitinase. In flask conditions, a combination of soluble starch and yeast extract produced the greatest amount of chitinase (5.1 units/ml) and its supernatant had the highest aphicidal activity. An optimal quantitative combination of the two substrates, estimated by a response surface method, enabled the supernatant to have 15.7 units/ml of chitinase activity and 3.7 ml/l of median lethal concentration ($LC_{50}$) of toxicity against cotton aphid adults in laboratory conditions. In the scale-up conditions, overall supernatant had 25-28 units/ml of chitinase activity. Decrease in pH and limitation of dissolved oxygen (DO) during cultures were significantly related to the yield of chitinase. These results suggest that the substrate-dependent chitinase production can be background information for optimizing a culture medium, and pH and DO are critical factors in maximizing the production in scale-up conditions.

• The Transactions of the Korean Institute of Power Electronics
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• v.22 no.2
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• pp.102-108
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• 2017

Proper design guides are proposed for a practical dual-active bridge (DAB) converter based on the mathematical model on the steady state. The DAB converter is popular in bidirectional application due to its zero-voltage capability and easy bidirectional operation for seamless control, high efficiency, and performance. Some design considerations are taken to overcome the limitation of the DAB converter. The practical design methodology of power stage is discussed to minimize the conduction and switching losses of the DAB converter. Small-signal model and frequency response are derived and analyzed based on the generalized average method, which considers equivalent series resistance, to improve the dynamics, stability, and reliability with voltage regulation of the practical DAB converter. The design of closed-loop control is discussed by the derived small-signal model to obtain the pertinent gain and phase margin in steady-state operation. Experimental results of a 3.3 kW prototype of DAB converter demonstrate the validity and effectiveness of the proposed methods.

• Journal of radiological science and technology
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• v.20 no.2
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• pp.79-82
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• 1997

Image-based three dimensional radiation treatment planning(3D RTP) has a potential of generating superior treatment plans. Advances in computer technology and software developments quickly make 3D RTP a feasible choice for routine clinical use. However, it has become clear that an evaluation of a 3D plan is more difficult than a 2D plan. A number of tools have been developed to facilitate the evaluation of 3D RTP both qualitatively and quantitatively. For example, beam's eye view(BEV) is one of the most powerful and time-saving method as a qualitative tools. Dose-volume histogram(DVH) has been proven to be one of the most valuable methods for a quantitative tools. But it has a limitation to evaluate several different plans for biological effects of the tissue and critical organ. Therefore, there is a strong interest in developing quantitative models which would predict the likely biological response of irradiated organs and tissues, such as tumor control probability(TCP) and normal tissue complication probability(NTCP). DVH and NTCP of hepatoma were evaluated for three dimensional conformal radiotherapy(3D CRT). Also, 3D RTP was analysed as a dose optimization based on beam arrangement and beam modulation.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.2
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• pp.113-119
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• 2006

Coronary artery disease is a loading cause of morbidity and mortality across the world. Percutaneous coronary intervention has become the major technique of revascularization. However, restenosis remains a major limitation of this procedure. Recently the need for repeat intervention due to restenosis, the most vexing long-term failure of percutaneous coronary intervention, has been significantly reduced owing to the introduction of two major advances, intracoronary brachytherapy and the drug-eluting stents. Intracoronary brachytherapy has been employed in recent years to prevent restenosis lesions with effective results, principally in in-stent restenosis. Restenosis is generally considered as au excessive form of normal wound healing divided up in precesses: elastic recoil, neointimal hyperplasia, and negative vascular remodeling. Restenosis has previously been regarded as a proliferative process in which neointimal thickening, mediated by a cascade of inflammatory mediators and other factors, is the key factor. Ionizing radiation has been shown to decrease the proliferative response to injury in animal models of restenosis. Subsequently, several randomized, double blind trials have demonstrated that intracoronary brachytherapy can reduce the rates of both angiographic restenosis and clinical event rates in patients undergoing percutaneous coronary intervention for in stent restenosis. Some problems, such as late thrombosis and edge restenosis, have been identified as limiting factors of this technique. Brachytherapy is a promising method of preventing and treating coronary artery restenosis.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.38 no.8
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• pp.27-33
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• 2001

The performance of the ordinary Fiber Bragg Grating(FBG) sensor strain measurement system, which uses Fabry-Perot filter for scanning wavelength, has limitation for application because of hysteresis characteristics of PZT element in the filter, slow scan rate of the filter and the high cost of system. We proposed and experimented a multiple FBG sensor system using light emitting diode(LED) as a light source and adapting Code Division Multiplexing(CDM) method to separating out individual sensor signal. Output signals for a applied static and dynamic strain and crosstalk levels between sensor signals were measured. The price of the system is very loss and the response speed is very fast. Crosstalk levels between sensor signals below - 30 dB were demonstrated.

• The Transactions of the Korean Institute of Power Electronics
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• v.21 no.1
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• pp.58-64
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• 2016

This study presents a design method for a single-loop voltage controller that is suitable for an arbitrary waveform generator (AWG). The voltage control algorithm of AWG should ensure high dynamic performance and should attain sufficient robustness to disturbances such as inverter nonlinearity, sensor noise, and load current. By analyzing the power circuit of AWG, control limitation and control target are presented to improve the dynamic performance of AWG. The proposed voltage control algorithm is composed of a single-loop output voltage control, an inverter current feedback term to improve transient response, and a load current feedforward term to prevent voltage distortion. The guideline for setting control gain is presented based on output filter parameters and digital time delay. The performance of the proposed algorithm is proven by experimental results through comparison with the conventional algorithm.

• Journal of the Korea Institute of Military Science and Technology
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• v.22 no.2
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• pp.266-277
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• 2019

In modern warfare, securing time for preemptive response is recognized as an important factor of victory. The naval combat system, the core of naval forces, also strives to increase the effectiveness of engagement by improving its real-time information processing capabilities. As part of that, it is considered to use the TPR-tree in the naval combat system's target indexing because spatio-temporal searches can be performed quickly even as the number of target information increases. However, because the TPR-tree is slow to process updates, there is a limitation to handling frequent updates. In this paper, we present a method for improving the update performance of TPR-tree by applying the bottom-up update scheme, previously proposed for R-tree, to the TPR-tree. In particular, we analyze the causes of overlaps occurring when applying the bottom-up updates and propose ways to limit the MBR expansion to solve it. Our experimental results show that the proposed technique improves the update performance of TPR-tree from 3.5 times to 12 times while maintaining search performance.

• 한국지구물리탐사학회:학술대회논문집
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• 2007.06a
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• pp.329-336
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• 2007

For scaling of the gradient of misfit function, we develop a new pseudo-Hessian matrix constructed by combining amplitude field and pseudo-Hessian matrix. Since pseudo- Hessian matrix neglects the calculation of the zero-lag auto-correlation of impulse responses in the approximate Hessian matrix, the pseudo-Hessian matrix has a limitation to scale the gradient of misfit function compared to the approximate Hessian matrix. To validate the new pseudo- Hessian matrix, we perform frequency-domain elastic full waveform inversion using this Hessian matrix. By synthetic experiments, we show that the new pseudo-Hessian matrix can give better convergence to the true model than the old one does. Furthermore, since the amplitude fields are intrinsically obtained in forward modeling procedure, we do not have to pay any extra cost to compute the new pseudo-Hessian. We think that the new pseudo-Hessian matrix can be used as an alternative of the approximate Hessian matrix of the Gauss-Newton method.

• Journal of Power System Engineering
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• v.3 no.1
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• pp.55-59
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• 1999

Generally, T.G(Tacho-generator, Tachometer) sensor is used widely for sensing the angular velocity in rotary machine. By limitation of T.G sensor's structure, the sensed angular velocity include a periodic noise, and the noise is called "ripple" as an electrical term. To reduce the effecting of the ripple, many kinds of filters are designed and installed, but there is necessary a trade off between response time and adapted frequency band. In this paper, we propose a generalized observer to estimate an angular velocity from the output signal of T.G sensor. The generalized observer is proposed firstly for continue systems, and it is applied to DC servo motor with T.G sensor. For simulation, we measure T.G signals at 60, 400, 570 rpm respectively, and analysis those to obtain the resonance frequency of ripple by FFT method. To verify the effectiveness of the proposed algorithm, we compare the results with those of a RC low frequency band filter.