Evaluation of DVH and NTCP in Hepatoma for 3D Conformal Radiation Therapy

3차원 입체조형치료에 대한 간암의 선량분포와 정상조직손상확률의 평가

  • Chung, Kap-Soo (Dept. of Radiotechnology, Seoul Health Junior College) ;
  • Yang, Han-Joon (Dept. of Radiotechnology, Seoul Health Junior College) ;
  • Ko, Shin-Gwan (Dept. of Radiotechnology, Seoul Health Junior College)
  • 정갑수 (서울보건전문대학 방사선과) ;
  • 양한준 (서울보건전문대학 방사선과) ;
  • 고신관 (서울보건전문대학 방사선과)
  • Published : 1997.12.20

Abstract

Image-based three dimensional radiation treatment planning(3D RTP) has a potential of generating superior treatment plans. Advances in computer technology and software developments quickly make 3D RTP a feasible choice for routine clinical use. However, it has become clear that an evaluation of a 3D plan is more difficult than a 2D plan. A number of tools have been developed to facilitate the evaluation of 3D RTP both qualitatively and quantitatively. For example, beam's eye view(BEV) is one of the most powerful and time-saving method as a qualitative tools. Dose-volume histogram(DVH) has been proven to be one of the most valuable methods for a quantitative tools. But it has a limitation to evaluate several different plans for biological effects of the tissue and critical organ. Therefore, there is a strong interest in developing quantitative models which would predict the likely biological response of irradiated organs and tissues, such as tumor control probability(TCP) and normal tissue complication probability(NTCP). DVH and NTCP of hepatoma were evaluated for three dimensional conformal radiotherapy(3D CRT). Also, 3D RTP was analysed as a dose optimization based on beam arrangement and beam modulation.

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