• Communications for Statistical Applications and Methods
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• v.12 no.3
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• pp.743-758
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• 2005

This paper consider penalized likelihood regression with data from exponential family. The fast computation method applied to Gaussian data(Kim and Gu, 2004) is extended to non Gaussian data through asymptotically efficient low dimensional approximations and corresponding algorithm is proposed. Also smoothing parameter selection is explored for various exponential families, which extends the existing cross validation method of Xiang and Wahba evaluated only with Bernoulli data.

• Proceedings of the IEEK Conference
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• 2003.11a
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• pp.149-152
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• 2003

This paper presents a method to find motion vectors that are closer to true motion with noisy images for simultaneous noise reduction and do-interlacing. The proposed method requires four interlaced field images: one noisy field image and three field images from which noise is already removed. The validation of motion provides accurate motion vectors and allows us to utilize them even in very noisy environment. The validated motion vectors are first used for the noise reduction, buffered and used later for the noise reduction and de -interlacing.

• Journal of the Korean Data and Information Science Society
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• v.26 no.2
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• pp.517-524
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• 2015

Unlabeled examples are easier and less expensive to be obtained than labeled examples. In this paper semisupervised approach is used to utilize such examples in an effort to enhance the predictive performance of nonlinear quantile regression problems. We propose a semisupervised quantile regression method named semisupervised support vector quantile regression, which is based on support vector machine. A generalized approximate cross validation method is used to choose the hyper-parameters that affect the performance of estimator. The experimental results confirm the successful performance of the proposed S2SVQR.

• Journal of the Korean Data and Information Science Society
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• v.19 no.4
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• pp.1327-1334
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• 2008

Mixed effect binomial regression models are widely used for analysis of correlated count data in which the response is the result of a series of one of two possible disjoint outcomes. In this paper, we consider kernel extensions with nonparametric fixed effects and parametric random effects. The estimation is through the penalized likelihood method based on kernel trick, and our focus is on the efficient computation and the effective hyperparameter selection. For the selection of hyperparameters, cross-validation techniques are employed. Examples illustrating usage and features of the proposed method are provided.

• Journal of the Korean Data and Information Science Society
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• v.21 no.2
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• pp.363-369
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• 2010

In this paper we propose a mixed-effects least squares support vector regression (LS-SVR) for longitudinal data. We add a random-effect term in the optimization function of LS-SVR to take random effects into LS-SVR for analyzing longitudinal data. We also present the model selection method that employs generalized cross validation function for choosing the hyper-parameters which affect the performance of the mixed-effects LS-SVR. A simulated example is provided to indicate the usefulness of mixed-effect method for analyzing longitudinal data.

• Journal of the Korean Data and Information Science Society
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• v.19 no.3
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• pp.789-800
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• 2008

Current credit evaluation models based on financial data make use of smoothing estimated default ratios which are transformed from each financial variable. In this work, some problems of the credit evaluation models developed by financial experts are discussed and we propose improved credit evaluation models based on the stepwise variable selection method and Box-Cox transformed data whose distribution is much skewed to the right. After comparing goodness-of-fit tests of these models, the validation of the credit evaluation models using statistical methods such as the stepwise variable selection method and Box-Cox transformation function is explained.

• Proceedings of the Korean Statistical Society Conference
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• 2003.05a
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• pp.167-170
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• 2003

We develop semiparametric methods for matched case-control studies using regression splines. Three methods are developed: an approximate crossvalidation scheme to estimate the smoothing parameter inherent in regression splines, as well as Monte Carlo Expectation Maximization (MCEM) and Bayesian methods to fit the regression spline model. We compare the approximate cross-validation approach, MCEM and Bayesian approaches using simulation, showing that they appear approximately equally efficient, with the approximate cross-validation method being computationally the most convenient. An example from equine epidemiology that motivated the work is used to demonstrate our approaches.

• YAKHAK HOEJI
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• v.41 no.5
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• pp.539-546
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• 1997

Capillary electrophoresis (CE) is perceived as an attractive tool for the analysis of pharmaceuticals and biological materials because of their high separation efficiency, easy separation and low running cost. New concept of micellar electrokinetic capillary chromatography (MECC) expanded the application of CE to the separation of neutral molecules. Validation of CE as an analytical technique for quality control of pharmaceuticals should be confirmed by quantitative analysis and the peak confirmation. In this study, the quantitative analyses of various types of neutral, acidic and basic components (acetaminophen, caffeine, ascorbic acid, riboflavin, thiamine, chlorpheniramine, phenylpropanolamine, dl-methylephedrine and dextromethorphan) in complex cold medicines have been accomplished using CE. Combined methods of MECC using SDS and capillary zone electrophoresis lowering the pH of running buffer were adopted to determine the ingredients in capsule type or liquid formula complex medicines without particular sample pretreatment. The results indicate that CE is a promising technique for quality control analysis of pharmaceuticals as a validation method.

• YAKHAK HOEJI
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• v.48 no.1
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• pp.60-64
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• 2004

Near-infrared (NIR) spectroscopy was used to determine rapidly and nondestructively the content of ambroxol in intact ambroxol tablets containing 30 mg (12.5％ m/m nominal concentration) by collecting NIR spectra in range 1100-1750 nm. The laboratory-made samples had 10.3∼15.9％ m/m nominal ambroxol concentration. The measurements were made by reflection using a fiber-optic probe and calibration was carried out by partial least square regression (PLSR) with autoscaling. Model validation was performed by randomly splitting the data set into calibration and validation data set (7 samples as a calibration data set and 5 samples as a validation data set). The developed NIR method gave results comparable to the known values of tablets in a laboratorial manufacturing Process, standard error of calibration (SEC) and standard error of prediction (SEP) being 0.49％ and 0.49％ m/m respectively. The method showed good accuracy and repeatability NIR spectroscopic determination in intact tablets allowed the potential use of real time monitoring for a running production process.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.8
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• pp.972-979
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• 1999

QFT(Quantitative Feedback Theory) is a very practical design technique that emphasizes the use of feedback for achieving the desired system performance tolerances in despite of plant uncertainty and disturbance. The fundamental concept of QFT is a loop shaping procedure that a suitable controller can be found by shaping a nominal loop transfer function. The loop shaping synthesis involves the identification of a structure and the specialization of parameter optimization of a desired system. This paper presents an improved loop shaping approach of QFT with model validation using GA(Genetic Algorithm). The method presented in this paper removes the problems of iterative operation, transformation error, and model validation in the conventional methods without consideration of frequency domain.