• Korean Journal of Occupational Health Nursing
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• v.25 no.1
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• pp.55-64
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• 2016

Purpose: The aim of this study was to investigate the association between job stress and metabolic syndrome among male workers. Methods: A total of 396 male workers employed in an electronic company, located in 'P' city, Gyeonggi Province, who had taken medical examination at the 'D' hospital, volunteered in this study. All the data used in this study were obtained from 'D' hospital after getting consent and permission from the workers. General and occupational characteristics, medical history, and health-related behaviors of the subjects were obtained by self-administered questionnaire. Results: The highest occupational stress by sub-sector was reported in the order of insufficient job control, organizational system, lack of reward, job demand, job insecurity, physical environment, job culture, and relationship conflict. The prevalence rate of metabolic syndrome of the participants was 19.9%. The results of the multiple logistic regression analysis on metabolic syndrome of the subjects indicated that the syndrome was significantly higher among those with family history, smoking habit and ex-smoking, working duration of 3 years and over, and with higher total score of occupational stress. It was significantly more prevalent, when the degree of stress was high in the sub-sectors of occupational stress; job autonomy, job insecurity, lack of reward, and job culture. Conclusion: In conclusion, it is necessary to implement a plan to efficiently manage the job stress of these male workers, as the probability of metabolic syndrome increased with the increase of occupational stress. Furthermore, considering the highest occupational stress was found to be job autonomy among its sub-sectors, it is necessary to prepare various measures to enhance the autonomy of such employees.

• Korean Journal of Occupational Health Nursing
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• v.25 no.4
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• pp.384-393
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• 2016

Purpose: The purpose of this study was to examine the effectiveness of Participatory Action-Oriented Training (PAOT) programs in korean manufacture workers with metabolic syndrome for three years. Methods: A total of 890 workers with risks of metabolic syndrome were recruited from one workplace. The experimental group (n=51) received PAOT program for the preventive management on metabolic syndrome, while the control group (n=51) received conventional program. Results: In the experimental group who participated in PAOT program, percentage of achieved action plans was 73.4% at three months, 75.8% at six months, 82.8% at three years. After three years, the rate of risk factor in the experimental group has significantly decreased from $1.94{\pm}1.77$ to $0.76{\pm}1.25$ for moderate exercise, and from $1.72{\pm}2.01$ to $1.04{\pm}1.59$ for the strenuous exercise. Systolic and diastolic blood pressure has significantly decreased from $125.06{\pm}11.83$ to $117.65{\pm}19.94$, from $83.45{\pm}13.38$ to $76.39{\pm}8.09$ mmHg. In addition, risk factor score also decreased from $3.31{\pm}0.61$ to $1.41{\pm}0.89$. Conclusion: To improve the effectiveness of PAOT program for the management of risk factors of metabolic syndrome, there is a need to continue implement programs and analyze the long-term effects are required in the workplace.

• The Journal of the Korea Contents Association
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• v.15 no.6
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• pp.314-325
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• 2015

The goal of this study was to evaluate the relationship between metabolic syndrome risk factors and health promotion behavior in general hospital nurses. Data were conducted using a structured questionnaire survey with 450 registered nurses in a general hospital in Gyeonggido. Data were collected from October 6 to October 31, 2014. The data were analyzed using SPSS/WIN 21.0. version. The overall prevalence of metabolic syndrome was 8.0% for nurses at a general hospital. The mean score of Health promotion lifestyle profile was 2.53( range: 1.22~3.44). The high prevalence risk groups for metabolic syndrome was between 26 and 30 yr of age, ICU nurses and drinking one or two times/1wk. The study indicates that hospital administrators should focus on job circumstances of nurses(especially nurses classified as high prevalence risk for metabolic syndrome) for improvement and prevention of MS prevalence risk.

• KIEAE Journal
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• v.17 no.5
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• pp.95-100
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• 2017

Purpose: The purpose of this study is to investigate the prior art based on deep learning to objectively calculate the metabolic rate which is the subjective factor for the PMV optimum control and to make a plan for future research based on this study. Methods: For this purpose, the theoretical and technical review and applicability analysis were conducted through various documents and data both in domestic and foreign. Results: As a result of the prior art research, the machine learning model of artificial neural network and deep learning has been used in various fields such as speech recognition, scene recognition, and image restoration. As a representative case, OpenCV Background Subtraction is a technique to separate backgrounds from objects or people. PASCAL VOC and ILSVRC are surveyed as representative technologies that can recognize people, objects, and backgrounds. Based on the results of previous researches on deep learning based on metabolic rate for occupational metabolic rate, it was found out that basic technology applicable to occupational metabolic rate calculation technology to be developed in future researches. It is considered that the study on the development of the activity quantity calculation model with high accuracy will be done.

• Korean Journal of Head & Neck Oncology
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• v.37 no.1
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• pp.17-22
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• 2021

Background/Objectives: To evaluate clinical significance of FDG PET-CT for detection of residual cancer cells after curative radiation therapy or chemoradiotherapy for patients with squamous cell carcinoma (SCC) of Head and Neck Materials & Methods: A retrospective analysis of patients with SCC of Head and neck with curative radiotherapy or chemoradiotherpy between June 2011 and Jan. 2019 was performed. Sixty patients were treated with Intensity-modulated radiotherapy (IMRT). The Metabolic responses were evaluated on the post-treatment FDG PET-CT at 12 weeks after curative radiotherapy completion. Results: Median follow up was 51.5 months (3-102). The overall survival (OS), disease free survival (DFS), local control rate (LCR), and Distant metastasis free survival (DMFS) at 5 years were 80.5%, 80.1%, 87.7% and 89.1%. Metabolic CR was found in 43 (71.7%) and partial metabolic response (PR) was noted in 17 (14.6%). Metabolic CR was significantly correlated with OS, DFS, LCR, and DMFS. On multivariate analysis, Metabolic CR remained significant for DFS and LCR. Conclusion: Metabolic CR on post-radiotherapy FDG PET-CT is highly predictive of increased DFS and LCR in patients with head and neck cancer.

• The Korea Journal of Herbology
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• v.30 no.2
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• pp.11-18
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• 2015

Objectives : Polygoni Multiflori Radix (Jeokhasuo in Korean) is a Oriental traditional herbs widely used in East Asian countries. Overconsumption of fructose results in hypertension, dyslipidemia, obesity and impaired glucose tolerance which have documented as a risk of cardiovascular diseases. This experimental study was designed to investigate the beneficial effects of an ethanol extract from Polygoni Multiflori Radix (PMR) in high-fructose (HF) diet-induced metabolic syndrome rat model. Methods : Sprague-Dawley (SD) rats were divided into three groups; Control group, receiving regular diet and tap water, HF group, and HF + PMR group both receiving supplemented with 65% fructose (n=10), respectively. The HF + PMR group initially received HF diet with PMR (100 mg/kg/day) for 8 weeks. Results : PMR significantly prevented the metabolic disturbances such as hyperlipidemia, hypertension and impaired glucose tolerance. Chronic treatment with PMR significantly decreased body weight, fat weight and adipocyte size, suggesting a role of anti-obesity effect. PMR led to improve the hyperlipidemia through the increase in HDL cholesterol level as well as the decrease in triglyceride and LDL cholesterol level. In addition, PMR suppressed adhesion molecules and endothelin-1 (ET-1) expression in aorta resulting in the decrease of hypertension. In muscle tissue, PMR significantly recovered the HF-induced insulin resistance through increase of insulin receptor substrate-1 (IRS-1), p-$AMPK{\alpha}1/2$, and p-Akt expression. PMR improved HF-induced metabolic disorders and its action was caused by energy metabolism-mediated insulin signaling activation. Conclusions : These results demonstrate that PMR may be a beneficial therapeutic for metabolic syndrome through the improvement of hyperlipidemia, obesity, insulin resistance and hypertension.

• Journal of Industrial Convergence
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• v.20 no.11
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• pp.213-219
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• 2022

The purpose of this study was to examine the effect of balance training on metabolic syndrome indicators and functional fitness. For this purpose, a 12-week balance training was conducted for 16 elderly women who usually complain of back and shoulder pain. In addition, of the 16 subjects, 8 were classified into the exercise group and 8 into the control group, and the effectiveness of the training program was verified. As a result of examining the metabolic syndrome index and functional fitness before and after 12 weeks of balance training, the following results were obtained. First, a significant interaction was shown in the metabolic syndrome index before and after 12 weeks of balance training. Second, there was a significant interaction in functional fitness before and after 12 weeks of balance training. This confirmed that balance training had a positive effect on functional fitness along with positive changes in metabolic syndrome in elderly women. In the future, it is necessary to clarify the effect of balance training through the expansion of the training period and measurement variables.

• Research in Community and Public Health Nursing
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• v.21 no.4
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• pp.409-418
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• 2010

Purpose: This study aimed to estimate the effects of a regular walking exercise program on metabolic syndrome, cardiovascular risk factors, and depressive symptoms among the elderly with diabetic mellitus (DM) based on the Theory of Reasoned Action (TRA). Methods: This study has randomized and stratified experimental design with experimental and control groups. We developed a regular walking exercise program suitable for the elderly with DM based on the guidance of AAHPERD. The experimental group participated in the regular walking exercise program, which contains walking exercise 3 times a week and 50 minutes each time for 3 months and education on controlling diet and preventing complications once a week and 20 minutes each time for 4 weeks. Post-test was conducted after 3 months to estimate metabolic syndrome, cardiovascular risk factors, and depressive symptoms. Results: The regular walking exercise program was effective for decreasing the waist size, the level of fasting blood glucose (FBG) and triglyceride (TG), cardiovascular risk factors and the severity of depressive symptoms among the elderly with DM. Conclusion: The incidence of complications would be decreased by applying a regular walking exercise program.

• Journal of Applied Biological Chemistry
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• v.56 no.3
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• pp.171-177
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• 2013

Efficient extraction of total proteins from soil microorganisms is tedious because of small quantity. In this regard, an improved method for extraction of whole cell proteins is developed from soil microorganisms, Saccharomyces cerevisiae and Pichia pastoris. of which the cell wall are very strong. Pretreatment with NH4OH prior to the final extraction using NaOH/SDS was tried under the basis that ammonium ion was possible to enhance the permeability and/or to weaken the yeast cell walls. The pre-treatment of yeast cells with NH4OH drastically enhanced the protein extraction when it was compared with control (without NH4OH pre-treatment). At the pre-treatment of 0.04 N NH4OH at pH 9.0, about 3 fold of proteins was obtained from p. pastoris. Ammonium hydroxide appears to penetrate into the yeast cell walls more readily at basic pH. The effect of NH4OH pretreatment was pH dependent. The methods developed in this experiment might be applicable for an effective extraction of yeast proteins for the purpose of biochemical studies, especially proteomic analysis.

• Journal of Applied Biological Chemistry
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• v.56 no.2
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• pp.109-112
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• 2013

Azole fungicides are one of the most wide-spread antifungal compounds in agriculture and pharmaceutical applications. Their major mode of action is the inhibition of ergosterol biosynthesis, giving depletion of ergosterol, precursors and abnormal steroids. However, metabolic consequences of such inhibition, other than steroidal metabolitesare not well established. Comprehensive metabolic profiles of Saccharomyces cerevisiae has been presented in this study. Wild type yeast was treated either with glucose as control or azole fungicide (ketoconazole). Both polar metabolites and lipids were analyzed with gas chromatography-mass spectrometry. Approximately over 180 metabolites were characterized, among which 18 of them were accumulated or depleted by fungicide treatment. Steroid profile gives the most prominent differences, including the accumulation of lanosterol and the depletion of zymosterol and ergosterol. However, the polar metabolite profile was also highly different in pesticide treatment. The concentration of proline and its precursors, glutamate and ornithine were markedly reduced by ketoconazole. Lysine and glycine level was also decreased while the concentrations of serine and homoserine were increased. The overall metabolic profile indicates that azole fungicide treatment induces the depletion of many polar metabolites, which are important in stress response.