• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.5
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• pp.921-929
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• 2008

Recently, many researches have been conducted to solve data heterogeneity as a way for data integration. The elements of the system that we suggest are an XMDR wrapper and XMDR Repository. XMDR wrapper solves the heterogeneity of the existing system by creating the interface based on the standard information of XMDR, and performing the inter-conversion between global XMDR query and local query using mapping data on standard information and local schema. XMDR Repository are composed of XMDR which manages the mapping data on standard information and local schema, and of Proxy DB which saves the accomplished results. With XMDR wrapper and XMDR Repository, users can use the same interface, and they need not conduct repeated queries since XMDR wrapper not only solves the heterogeneity of the schema using the meta-semantic ontology of XMDR, but also considers the heterogeneity accompanying the meaning of the value through instance semantic ontology. Therefore, in this paper we suggest the grid wrapper for the solution of data heterogeneity and efficient data integration.

• Journal of the Korean Society for information Management
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• v.29 no.1
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• pp.231-251
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• 2012

In this study, Linked Data was used for extending bibliographic data, because Linked Data provides shareable identifiers, data structures, and link information. Linked Data is especially efficient in expanding bibliographic data integrated with bibliographic ontology. Therefore, Linked Data and bibliographic ontologies were analyzed and available Linked Data was suggested. By linking between meta-data schemes, bibliographic data, and authority data, issues for the effective Linked Data sharing were suggested: 1) selecting proper Linked Data for each bibliographic organization, 2) linking between different Linked Data, and 3) developing their own Linked Data for each bibliographic organization.

• Annual Conference on Human and Language Technology
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• 2006.10e
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• pp.81-88
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• 2006

컴퓨터를 활용한 지식과 정보의 고도 처리를 위해 온톨로지를 구축하고 활용하려는 요구가 강해지고 있다. 이런 요구에 부흥하여 온톨로지의 구축 방법에 대한 많은 연구가 이루어지고 있다 그러나 현재까지의 온톨로지 구축 이론과 온톨로지 개발 도구가 실제 구현 목적과 사례에 따라 제한적인 부분에서 개발되어 사용되고 있다. 그러므로 구축하고자 하는 분야의 온톨로지에 맞는 적절한 구축 프로세스와 도구가 필요하다. 분야 온톨로지(domain ontology)를 구축함에 있어 특정 분야의 전문가 또는 비전문가가 언어자원으로부터 지식을 개념화(conceptualization), 형식화(formalization)하여 온톨로지를 구축할 수 있도록 분야 관련 언어자원에 근거하여 온톨로지를 구축할 수 있는 온톨로지 구축 프로세스(OntoProcessl))를 제안한다. 그리고, 다수의 온톨로지 구축자가 동시에 같은 분야의 온톨로지를 구축할 경우, 개념화 과정에서 서로 다른 구축자가 동일한 개념을 중복 정의하거나, 형식화 과정에서 형식언어 이해 부족으로 인한 구축 능률 저하 문제가 발생할 수 있다. 이를 위해 메타 온톨로지(meta ontology)를 이용하여 다중 온톨로지를 구축할 때 발생하는 문제를 해결하는 다중 온톨로지 구축 프로세스를 제안한다. 현재 이 프로세스에 근거하여 온톨로지 구축 시스템(OntoCS2))을 개발하였고 국가 IT 온톨로지 인프라 기술 개발 프로젝트에서 IT분야 온톨로지의 개발에 활용되고 있다.

• Proceedings of the KAIS Fall Conference
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• 2003.11a
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• pp.57-64
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• 2003

Achieving the beneficiary goal of recent discovery in human genome project still needs a way to retrieve and analyze the exponentially expanding bio-related information. Research on bio-related fields naturally applies knowledge discovered to the current problem and make inferences to extract new information where shared concepts and data containing information need to be defined and used in a coherent way. In such a professional domain, while the need to help users reduce their work and to improve search results has been emerged. methods for systematic retrieval and adequate exchange of relevant information are still in their infancy. The design of our system aims at improving the quality of information retrieval in a professional domain by utilizing both corpus-based and concept-based ontology. Meta-rules of helping users to make an adequate query are formed into an ontology in the domain. The integration of those knowledge permits the system to retrieve relevant information in a more semantic and systematic fashion. This work mainly describes the query models with details of GUI and a secondary query generation of the system.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.05a
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• pp.1136-1141
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• 2003

Due to the lack of digitally usable standards, it has been known to be difficult to handle the biological data. For example, the name of genes and proteins changes over time or has several synonyms indicating different entities. To cope with these problems, several communities, including the Gene Ontology Consortium and PubGene are making their efforts to move science toward the semantic web vision. Although some progress has been made, its expressivity is not sufficient for full-fledged ontological modeling and reasoning. This paper suggests a methodology for representing and extracting biological knowledge by using Web Ontology Language (OWL) as an extension of Resource Description Framework Schema (RDFS). Some benefits of our approach are: (1) to ensure extended sharing of biological meta data on the Web, and (2) to enrich additional expressivity and the semantics of RDFS+OWL.

• Journal of Periodontal and Implant Science
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• v.51 no.1
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• pp.18-29
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• 2021

Purpose: The aim of this study was to compare the characteristic expression patterns of advanced periodontitis in 2 cohort data sets analyzed using different microarray platforms, and to identify differentially expressed genes (DEGs) through a meta-analysis of both data sets. Methods: Twenty-two patients for cohort 1 and 40 patients for cohort 2 were recruited with the same inclusion criteria. The 2 cohort groups were analyzed using different platforms: Illumina and Agilent. A meta-analysis was performed to increase reliability by removing statistical differences between platforms. An integrative meta-analysis based on an empirical Bayesian methodology (ComBat) was conducted. DEGs for the integrated data sets were identified using the limma package to adjust for age, sex, and platform and compared with the results for cohorts 1 and 2. Clustering and pathway analyses were also performed. Results: This study detected 557 and 246 DEGs in cohorts 1 and 2, respectively, with 146 and 42 significantly enriched gene ontology (GO) terms. Overlapping between cohorts 1 and 2 was present in 59 DEGs and 18 GO terms. However, only 6 genes from the top 30 enriched DEGs overlapped, and there were no overlapping GO terms in the top 30 enriched pathways. The integrative meta-analysis detected 34 DEGs, of which 10 overlapped in all the integrated data sets of cohorts 1 and 2. Conclusions: The characteristic expression pattern differed between periodontitis and the healthy periodontium, but the consistency between the data sets from different cohorts and metadata was too low to suggest specific biomarkers for identifying periodontitis.

• Asia pacific journal of information systems
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• v.13 no.2
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• pp.145-170
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• 2003

Open Decision Support System(DSS) is an automated and transparent system that is built to be shared both within and across organizations. The open DSS has been thought to be a set of decision components that are communicating through Web protocols. These characteristics intuitively invite the Web services concepts, which are currently one of the new trends in network-based business services. However, web services still are not active enough to be autonomous, and to provide for composing functionalities. These lead to the motivation on building a sophisticated web service to contain these features and to utilize web services on behalf of the user. This paper aims to propose a new concept of Meta Web Service, a web service-based open DSS. Decision modules in a dynamic and open DSS can be viewed as a web service. The Meta Web Service understands the users problem statement with ontology, performs web service discovery, web service composition, and automatically generates codes for composite web service execution. A prototype of example web service has been developed to show the feasibility of the proposed idea.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.12
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• pp.2212-2220
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• 2006

Recently enterprises introduce EAI systems and legacy business which already obtained for data integration among legacy systems. EAI systems in cooperative transaction environment can be expected efficient retrieval as sharing and integrating. However existing legacy systems have to introduce particular EAI solution because it is difficult to adjust standard technology to EAI due to be managed independently without considering interoperability. For solving these problems we use metadata registry using data integration. Various types, semantic specification data heterogeneity and heterogeneity of systems, however, are occurred. Therefore retrieval system based on XMDR(extended Meta-Data Registry) for data interoperability in the web environment are proposed in this paper.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.457-461
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• 2013

Prostate cancer is a leading cause of death in male populations across the globe. With the advent of gene expression arrays, many microarray studies have been conducted in prostate cancer, but the results have varied across different studies. To better understand the genetic and biologic mechanisms of prostate cancer, we conducted a meta-analysis of two studies on prostate cancer. Eight key genes were identified to be differentially expressed with progression. After gene co-expression analysis based on data from the GEO database, we obtained a co-expressed gene list which included 725 genes. Gene Ontology analysis revealed that these genes are involved in actin filament-based processes, locomotion and cell morphogenesis. Further analysis of the gene list should provide important clues for developing new prognostic markers and therapeutic targets.

• The Journal of the Korea Contents Association
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• v.9 no.4
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• pp.55-64
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• 2009

For realizing ubiquitous computing, many research activities are geared towards various areas including embedded computing, RFID, USN, home networking, context-awareness, and etc. By using the ability of RFID technology to recognize a number of objects simultaneously, more convenient ubiquitous application services are effectively provided. In this case, RFID middleware playing a role as a bridge between RFID reader devices and application services is required as well. In this paper, we propose a method of handling a number of types of RFID reader devices in ALE middleware of EPCglobal. For this, the information of connection and data protocol for a reader device is stored in a database as ontology meta-data, and used to interpret the data read by a reader device. By adding ontology data into a database, even though an RFID device newly emerges, ALE middleware can not only handle the device, but also be effectively extended through reusing ontology data, without any changes in the middleware.