• Proceedings of the Korea Contents Association Conference
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• 2006.11a
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• pp.474-477
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• 2006

Recently, the needs for the virtual reality service of multimedia contents on the web are increasing. The services are provided by the parameter value of attribute informations of the contents. The Conventional method for managing the parameters is storing the informations separately for the contents, in this method managing and implementing the system are to be costing job. In this paper, a virtual reality service based on meta data is proposed. For the storing and managing the parameter information, we use the free space of the JPEG images. And for testing the effectiveness of the proposed system, we implemented the prototype virtual reality service model.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.4 s.247
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• pp.465-472
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• 2006

Recently, the regulations of the government and the concerns of people have rise to the interest in noise pollution levels as compared to other vehicles. In this area, many researchers have studied to reduce this noise in the field of automotive engineering. This paper proposes an optimal design scheme to reduce the noise of the intake system by adapting Kriging with two meta-heuristic techniques. For this, as a measuring tool for the performance of the intake system, the performance prediction software, was used. Then, the length and radius of each component of the current intake system are selected as input variables and the orthogonal arrays is adapted as a space-filling design. With these simulated data, we can estimate a correlation parameter in Kriging by solving the nonlinear problem with a genetic algorithm and find an optimal level for the intake system by optimizing Kriging estimated with simulated annealing. We notice that this optimal design scheme gives noticeable results and is a preferable way to analyze the intake system. Therefore, an optimal design for the intake system is proposed by reducing the noise of its system.

• Bulletin of the Korean Chemical Society
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• v.26 no.12
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• pp.1941-1945
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• 2005

To raises the possibility of designing effective inhibitors, 3D-QSAR for the inhibition of calcineurin-NFAT signaling by new N-(4-oxo-1(4H)-naphthalenylidene benzenesulfonamide derivatives as inhibitors of intracellular protein-protein interactions were studied using CoMFA and CoMSIA methodology. The three templates, N-(4-oxo-1(4H)-naphthalenylidene)benzenesulfonamide (A), benzenesulfonamide (B) and 4-oxo-1(4H)-naphthalenylidene (C) were selected to improve the statistic of the present 3D-QSAR models. The best models with combination of standard field in CoMFA, and steric field and electrostatic field in CoMSIA derived from the template, B and C, because most of the compounds tend not to be aligned in template A. From the based on the CoMFA and CoMSIA contour maps, the $R_1$ and $R_2$ groups on 4-oxo-1(4H) naphthalenylidene ring are steric favor. The ortho position on the benzenesulfonyl ring is steric disfavor and the meta position is steric favor. In addition, the oxygene atom of carbonyl group will have better inhibition activities as it has a negative charge favor. From these findings, we can conclude that the analyses of the contour maps provided insight into possible modification of molecules for effective inhibitiors.

• Health Policy and Management
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• v.11 no.3
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• pp.71-88
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• 2001

The purpose of this study is to analyze the cost-effectiveness of four medications for treating and preventing osteoporosis -HRT therapy(conjugated equine estrogen 0.625mg for 25 days and medroxyprogesterone acetate 5mg for 01112 days), Alendronate(10mg and 5mg), Active Vitamin D(Calcitriol), and Calcium. Total costs include the direct medical cost -examination fee, consultation fee, prescription fee, fee for preparing medications, and the price of pharmaceuticals- and the indirect cost of patients such as traffic expenses and time cost. In addition, the costs of monitoring in adverse reactions are added. The effects of four medications are expressed as BMD(Bone Mineral Density) percent change measured by DEXA(Dual Energy X-ray Absorptiometry) in lumbar spine(L2-L4) and femoral neck site. A mixed model based on meta analysis provides the estimates of effectiveness, which are then appled to the hypothetical cohort consisting of postmenopausal women at the age of 50-59. HRT therapy is the most cost-effective medication at 172,433.64 won (lumbar spine site) and 546,328.28 won (femoral neck site) per BMD percent change for osteoporosis. Alendronate 10mg is more cost-effective than Alendronate 5mg as 345,971.23 won and 378,441.63 won per lumbar BMD percent change at 0.991ｇ/$cm^2$, respectively. Alendronate 10mg is more cost-effective than Alendronate 5mg as 1,329,257.89 won and 1,467,291.23 won per femoral neck BMD percent change at 0.834ｇ/$cm^2$, respectively.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.232-239
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• 2009

Emerging social networking services provide a new paradigm for human-to-human communication. However, these services are centralized and managed by single service provider. In this paper, we propose MicroPost, a decentralized event notification service architecture for social applications based on publish/subscribe model. In our design space, event brokers are structured as an overlay network which provides the substrate of distributed peer-to-peer lookup service for storing and retrieving subscriptions with hashed keys. Event clients interact with event brokers to publish or subscribe social messages over the wide-area network. Using XML standards, we present an efficient algorithm to forward events for rendezvous-based matching in this paper. In our design space, the cost of routing is O(${\omega}log_kN$), where N is the number of event brokers, ${\omega}$ is the number of meta-data obtained from event messages, and k is a constant, which is selected by our design, to divide the identifier space and to conquer the lookup of given key. Consequently, what we achieved is an asynchronous social messaging service architecture which is decentralized, efficient, scalable, and flexible.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.3 no.1
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• pp.24-30
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• 2010

In this paper, a novel electrically small monopole type resonant antenna is proposed. The very short length monopole (${\iota}{\approx}{\lambda}_g/15$ ) acts as a capacitive element and the slot on the ground structure acts as an inductive element, hence the combined system with these two elements thus form an LC resonator. The equivalent circuit model of the antenna structure was used to analysis and qualify the design correctness. Although the proposed antenna has very small size, it shows good performances. The measured maximum gain and radiation efficiency of the fabricated antenna at the frequency of 2.1 GHz was 3.6 dBi and 77.8 %, respectively.

• Journal of Korean Library and Information Science Society
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• v.45 no.2
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• pp.235-260
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• 2014

This study aims to apply the concept of Internet of things to library and interpret a library as ecological space where human, thing and data are communicating and organically networking through internet. First, we defined various things existing in physical spaces of the real world and internet spaces as elements of Internet of Things. Then we proposed to apply a semantic web platform to integrate different meta-data formats and communication protocols from things. Finally, we provide the model of Internet of Things based on Semantic web to utilize a variety of information from things for library management and user service.

• Journal of Ocean Engineering and Technology
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• v.24 no.1
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• pp.20-33
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• 2010

The paper deals with strength design of a riser support installed on floating production storage and offloading (FPSO) vessel under various loading conditions - operation, extreme, damaged, one line failure case (OLFC) and installation. The design problem is formulated such that thickness sizing variables are determined by minimizing the weight of a riser support structure subject to stresses constraints. The initial design model is generated based on an actual FPSO riser support specification. The finite element analysis (FEA) is conducted using MSC/NASTRAN, and optimal solutions are obtained via moving least squares method (MLSM) in the context of response surface based approximate optimization. For the meta-modeling of inequality constraint functions of stresses, a constraint-feasible moving least squares method (CF-MLSM) is used in the present study. The method of CF-MLSM, compared to a conventional MLSM, has been shown to ensure the constraint feasibility in a case where the approximate optimization process is employed. The optimization results present improved design performances under various riser operating conditions.

• Journal of Preventive Medicine and Public Health
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• v.48 no.5
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• pp.225-230
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• 2015

Objectives: The epidemiological characteristics of breast cancer incidence by age group in Korean women are unique. This systematic review aimed to investigate the association between hormone replacement therapy (HRT) and breast cancer risk in Korean women. Methods: We searched electronic databases such as KoreaMed, KMbase, KISS, and RISS4U as well as PubMed for publications on Korean breast cancer patients. We also conducted manual searching based on references and citations in potential papers. All of the analytically epidemiologic studies that obtained individual data on HRT exposure and breast cancer occurrence in Korean women were selected. We restricted the inclusion of case-control studies to those that included age-matched controls. Estimates of summary odds ratio (SOR) with 95% confidence intervals (CIs) were calculated using random effect models. Results: One cohort and five case-control studies were finally selected. Based on the heterogeneity that existed among the six studies (I-squared=70.2%), a random effect model was applied. The summary effect size of HRT history from the six articles indicated no statistical significance in breast cancer risk (SOR, 0.983; 95% CI, 0.620 to 1.556). Conclusions: These facts support no significant effect of HRT history in the risk of breast cancer in Korean women. It is necessary to conduct a pooled analysis.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.1
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• pp.1-9
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• 2009

As many new drug substances contained various aromatic rings and fluorine attached to an electron rich aromatic ring or on the meta-position, a strategy towards improvement in aromatic fluorination of these compounds is highly desirable. The introduction of fluorine-18 onto aromatic rings showed in the limited condition containing electron withdrawing group (EWG) on the para- or ortho-position to get reasonable radiochemical yield so far. No-carrier added (NCA) [$^{18}F$]fluoroarene syntheses by iodonium salts recently reported that has the potential to greatly increase the yield in systems or positions that normally not reactive enough to give sufficient yields in simple model reaction. This review describes the methodological approach towards effective aromatic fluorination by diaryliodonium salts and future prospects in an application of novel PET radiotracer.