• 제목/요약/키워드: Meta analysis

검색결과 2,618건 처리시간 0.03초

Continuous wave of obturation technique에서 플러거의 다양한 적용 깊이에 따른 근단부 폐쇄효율 비교 (COMPARISON OF APICAL SEALING EFFICACIES USING DIFFERENT PLUGGING DEPTH IN CONTINUOUS WAVE OF OBTURATION TECHNIQUE)

  • 이상진;박정길;허복;김현철
    • Restorative Dentistry and Endodontics
    • /
    • 제32권6호
    • /
    • pp.491-497
    • /
    • 2007
  • 이 연구의 목적은 continuous wave of obturation technique으로 근관 충전을 할 때, 다양한 heat source plugger의 깊이에 따른 근단부 근관 폐쇄능력을 비교하는 것이었다. 직선 형태 발거 소구치를 #35/.06 크기까지 니켈티타늄 파일을 사용하여 성형 및 세정하였다. 성형과 세정이 완료된 치아를 heat source plugger의 적용 깊이에 따라 15개씩 5군으로 분류하였다. 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 양성 대조군을 제외한 모든 근관은 E&Q plus(Meta Biomed Co., Chungju, Korea)를 사용하여 #35/.06 gutta-percha cone으로 충전하였다. 모든 치아의 근첨공 주변 1 mm를 제외하고 nail varnish를 도포하였고 음성 대조군은 근첨공을 포함하여 전체 면을 도포하였다. 모든 시편을 1% 메틸렌블루 용액에 72시간 동안 보관한 다음 치근첨으로부터 1, 2, 3 mm 높이에서 수평으로 절단하였다. 각 단면을 $12.5{\times}2.5$배 현미경하에서 관찰하고 디지털 카메라로 촬영하였다. 염색제 누출 평가를 위해 aye-degree scoring system을 사용하였다. 각 절단면에서의 점수를 모두 합하여 한 시편의 점수로 사용하고 통계학적 분석을 하였다. 이 실험 조건하에서, 3-7 mm까지의 heat source plugger의 적용 깊이는 근단부 폐쇄에서 유의한 차이를 나타내지 않았다. 5-7 mm의 Buchanan's protocol을 포함한 3-7 mm를 모두 임상 적용에서 받아들여질 만하다고 보인다.

키토산의 치주조직 재생력에 대한 연구의 고찰: 조직계측학적 메타분석 (Study of chitosan's effects on periodontal tissue regeneration: a meta-analysis of the histomorphometry)

  • 양진혁;채경준;윤정호;정의원;이용근;조규성;채중규;김종관;최성호
    • Journal of Periodontal and Implant Science
    • /
    • 제38권1호
    • /
    • pp.7-14
    • /
    • 2008
  • Purpose: Chitosan & chitosan derivative(eg. membrane) have been studied in periodontal regeneration, and recently many studies of chitosan have reported good results. If chitosan's effects on periodontal regeneration are enhanced, we can use chitosan in many clinical and experimental fields. For this purpose, this study reviewed available literatures, evaluated comparable experimental models. Materials and Methods: Ten in vivo studies reporting chitosan's effects on periodontal tissue regeneration have been selected by use of the 'Pubmed' and hand searching. Results: 1. In Sprague Dawley rat calvarial defect models, amount of newly formed bone in defects showed significant differences between chitosan/chitosan-carrier/chitosan-membrane groups and control groups. 2. In beagle canine 1-wall intrabony defect models, amount of new cementum and new bone showed significant differences between chitosan/chitosan-membrane groups and control groups. The mean values of the above experimental groups were greater than the control groups. Conclusion: The results of this study have demonstrated that periodontal regeneration procedure using chitosan have beneficial effects, which will be substitute for various periodontal regenerative treatment area. One step forward in manufacturing process of chitosan membrane and in use in combination with other effective materials(eg. bone graft material or carrier) may bring us many chances of common use of chitosan in various periodontal area.

순차적 전달방식(STM)을 이용한 분산정보검색시스템의 설계 및 알고리즘 구현 (Design and Algorithm Implementation of a Distributed Information Retrieval System using Sequential Transferring Method(STM))

  • 윤희병;김용한;김화수
    • 정보처리학회논문지B
    • /
    • 제11B권5호
    • /
    • pp.603-610
    • /
    • 2004
  • 분산검색시스템은 중재자 또는 메타검색엔진에 의한 중앙통제로 인하여 중앙 시스템에 트래픽이 집중된다. 또한 중앙통제를 위한 복잡한 알고리즘의 설계와 별도의 하드웨어 설치 등의 비용 증가 문제가 발생한다. 따라서 이러한 문제를 해결하기 위해 여러 검색시스템이 서로 독립적인 검색기능을 가지면서도 중앙의 통제를 받지 않으면서 상호 협조할 수 있는 방식이 필요하다. 본 논문에서는 분산검색시스템과 관련된 여러 연구를 살펴보고 다중의 정보검색시스템이 중앙의 통제를 받지 않는 순차적 전달방식(STM)을 이용한 분산정보검색시스템의 Framework를 설계하며 이와 관련된 알고리즘을 구현한다 이를 위해 먼저 웹을 논리적으로 분할하여 관리하는 웹 분할 정책을 제시하며, 검색시스템의 수에 따른 순차적인 질의 처리방식을 각각 예제를 통해 설명한다. Framework에 적합한 정보검색시스템의 3 Layer구조와 각 Layer별 기능과 모듈을 또한 제시한다. 마지막으로, STM 알고리즘의 효율적 구현을 위하여 모듈 구조를 분석하고 이의 pseudocode 표현을 제시하며 서버간 순차적 질의 전달 시연과정을 통해 제안한 SIM 알고리즘이 효율적으로 동작함을 보여준다.

다양한 골 이식재의 임상 효과에 대한 고찰 (A study of the clinical effects of various bone graft materials)

  • 이승범;연제영;채경준;정의원;김창성;이용근;조규성;채중규;김종관;최성호
    • Journal of Periodontal and Implant Science
    • /
    • 제37권4호
    • /
    • pp.719-732
    • /
    • 2007
  • Purpose: Various bone graft materials are being used for periodontal tissue regeneration. Th materials are being developed continuously for ideal clinical effects. Therefore, it is necessary to identify the clinical characteristics of each bone graft material through comparing the various bone graft materials statistically and in doing so, proposing a more efficient bone graft material. In this study, the following results were attained through comparing the clinical effects among the bone graft materials, using the statistical method based on the clinical studies published at the department of periodontology of Yonsei hospital. Materials and Method: 6 selected studies of department of Periodontology at Yonsei University Hospital were based on clinical study of bone grafting in intrabony defects. It was compared the clinical parameters among the 6 clinical studies, using the statistical META analysis. Result: When comparing the probing depth reduction, there was a relatively great amount of decease when using the xenograft, Anorganic Bovine Derived Hydroxapatite Bone Matrix/Cell Binding Peptide(ABM/P-15: PepGen $P-15^{(R)}$) and the autogenous bone and absorbable membrane, d, 1-alctide/glycolide copolymer(GC: $Biomesh^{(R)}$). The allogfrafts showed a relatively low decrease in the probing depth and clinical attachment change. It also showed a slight decrease in the bone probing depth. The allografts showed various results according to different bone graft materials. When comparing the ABM/P-15 and bovine bone $powder(BBP^{(R)})$, ABM/P-15 showed a relatively high clinical attachment level and the bovine bone powder showed a relatively high clinical attachment level. The probing depth change and gingival recession change showed a lower value than the mean value between the two bone graft materials. The synthetic bone showed a relatively high decrease in clinical attachment level and periodontal probing depth change. There was a relatively larger amount of gingival recession when using Bioactive Glass(BG) but a relatively low bone regeneration effect was seen. Conclusion: Good restorative results of the periodontal tissue can be attained by applying the various bone graft materials being used today after identifying the accurate clinical effects.

복부비만 관련 임상시험의 국내외 연구경향 고찰 (Comparative Review of Current Clinical Trials on Abdominal Obesity)

  • 임제연;송윤경;임형호
    • 한방재활의학과학회지
    • /
    • 제20권2호
    • /
    • pp.63-77
    • /
    • 2010
  • Objectives : It is known that abdominal obesity increases the possibility of cardiovascular diseases, early death, and metabolic syndrome including dyslipidemia and insulin resistance. Clinical trials have been under way to verify the effectiveness of treatment for abdominal obesity. The objective of this study is to set criteria about how effective oriental medicine and acupuncture are in abdominal obesity. Methods : I manually search "www.clinicaltrial.gov", 4 Korean medical databases and 4 Korean medical journals of abdominal obesity. Search terms used were "abdominal obesity" or "visceral obesity". In order to see detail review, searching was performed from 01, 01, 2005 to 11, 31, 2009. And I classified all the searched studies into design, intervention, purpose, end point, diseases, condition and etc. Results : 1. I could search total 67 trials in "www.clinicaltrial.gov". I found 9, 10, 13, 8, 6 clinical trial from 2005 to 2009 every year. 2. Test on both gender and adult or adult and senior have been most frequent. 3. Randomization clinical trial is 51 cases that occupied 96.2%. 38 cases use control group. 4. Body mass index(BMI) and waist circunference(WC) are major criteria of abdominal obesity clincal trial. WC, BMI, abdominal fat mass, body weight are measured at end point of abdominal obesity clincal trial. 5. I could search total 86 cases in domestic study. I found 15, 23, 23, 20, 5 cases from 2005 to 2009 every year. 6. Test on female and adult have been most frequent in domestic study. 7. Randomization clincal trial is only 2 cases that occupied 2.3%. 62 cases use control group in domestic study. 8. BMI, body fat percent, WC, visceral-subcutaneous fat ratio(VSR), waist-hip ratio(WHR) are criteria of abdominal obesity clincal trial in domestic study. WC, BMI, abdominal fat mass, body weight are measured at end point of abdominal obesity clincal trial in domestic study. Conclusions : To improve abdominal obesity study in traditional korean medicine, it is need to activate clinical trial, meta analysis, develope of clinical practice guidelines, co-works with conventional medicine and etc.

본태성 진전에 대한 중의학 연구동향 (A Review on Treatment of Essential Tremor in Traditional Chinese Medicine)

  • 신아리;배영롱;임재유;이승환;김상호;임정화
    • 동의신경정신과학회지
    • /
    • 제28권2호
    • /
    • pp.95-107
    • /
    • 2017
  • Objectives: This study was performed to review studies on Essential Tremor (ET) in Traditional Chinese medicine (TCM). Methods: We reviewed papers in the China National Knowledge Infrastructure (CNKI) from 2007~2016. Search keywords were 原发性震颤, 特发性震颤, essential tremor and idiopathic tremor, and excluded non-clinical studies, non-related to ET or TCM studies, theses for degrees and non-Randomized Controlled Trial (RCT). The quality of the articles was assessed by Jadad scale and the Risk of Bias (RoB). Results: Thirteen studies were selected. 'Criteria for the diagnosis of ET' was most frequently used as diagnostic criteria. 'Tremor rating scale' was primarily used for outcome measurement. Meta-analysis of nine trials revealed the effective rate of acupuncture and Western medicine (WM+Acu) groups was significantly higher compared to the WM group (RR: 1.48, 95 percent CI: 1.20 to 1.82, p=0.0002, $I^2=0$ percent) and tremor rating scale was also significantly decreased in the treatment group (MD: -1.35, 95 percent CI: -2.17 to -0.54, p=0.001, $I^2=0$ percent). Also, effective rates of Electro-acupuncture (EA) and Chinese herbal medicine (CHM) groups were significantly higher than that of the WM group {(RR: 1.53, 95 percent CI: 1.22 to 1.92, p=0.0003, $I^2=0$ percent) in EA vs. WM and (RR: 1.35, 95 percent CI: 1.16 to 1.57, p<0.0001, $I^2=0$ percent) in CHM vs. WM}. However, the quality of selected clinical studies was poor. Conclusions: Treatment of ET in TCM may be more effective and safe than in Western medicine. Therefore, we hope this study will lead to further clinical research on treatment of ET in Korean medicine.

『중용』과 진화생물학의 대화 가능성 모색 (A Study of the Possibility of Interaction between the Doctrine of the Mean and Evolutionary Biology)

  • 김재경
    • 동양고전연구
    • /
    • 제54호
    • /
    • pp.155-182
    • /
    • 2014
  • 이 논문은 "중용"의 "천명지위성(天命之謂性)"과 "시중(時中)", 그리고 "천지위만물육(天地位萬物育)"의 이슈가 진화생물학의 유전자, 자연선택, 종 다양성 문제와 대화 가능한지 그 가능성을 검토하고 있다. 이를 위해 먼저 성리학과 진화생물학의 유사점과 차이점을 살펴보고, "중용"과 진화생물학의 접점이 무엇인지 모색하고 있다. 이 논문은 세 가지 점에서 "중용"과 진화생물학 사이의 대화 가능성을 검토한다. 첫번째는 인간 본성에 대해 천명지위성과 유전자의 관점에서 대화 가능한지 살펴본다. 두 번째는 존재 이유의 타당성을 시중과 자연선택의 관점에서 살펴본다. 세 번째는 생물간 상호 유연 관계를 천지위만물육과 종 다양성이라는 관점에서 살펴본다. 첫 번째 모색의 소주제들은 <리와 기 vs 유전자와 운반체>의 구조적 연관성, <성선 vs 이기적 유전자의 이타성>의 판단기준, <인 의 예 지 vs 후성규칙>에서 '후천적 선험' 도출 가능성이다. 두 번째 모색의 소주제들은 <천리의 뒤집힘[번(?)] vs 돌연변이>, <변/화 vs 진화>의 시간관, <시중 vs 자연선택/적응>의 메타meta적 접근이다. 세 번째 모색의 소주제들은 <리일분수理一分殊 vs 부분과 전체>의 프랙탈 구조, < 일기一氣 vs 생물간 상호 유연>의 상동관계, <천지위 만물육 vs 생태계>와 치중화致中和의 과제이다. 이러한 모색과 제안들에 대한 후속연구는 "중용"을 둘러싼 성리학 연구의 지평 확대를 가져 올 수 있다.

상호매체성의 이론과 그 적용 - 피터 그리너웨이의 <프로스페로의 서재>를 중심으로 (A Theory of Intermediality and its Application in Peter Greenaway's )

  • 박기현
    • 비교문화연구
    • /
    • 제19권
    • /
    • pp.39-77
    • /
    • 2010
  • The cinema of Peter Greenaway has consistently engaged questions of the relationship between the arts and particularly the relations of image and writing to cinema. When different types of images are correlated and merged with each other on the borders of painting, photography, film, video and computer animation, the interrelationships of the distinct elements cause a shift in the notion of the whole image. This analysis proposes to articulate the complex relationship between the 'interartial' dimension and the 'intermedial' dimension in Peter Greenaway's film, (1991). If the interartiality is interested in the interaction between various arts, including the transition from one to another, the intermediality articulates the same type of relationship between two or more media. The interactional relationship is the same on both sides; on the contrary, the relationship between art and media does not show the same symmetry. All art is based on one or more media - the media is a condition existence of art - but no art can't be reduced to the status of media. This suggests that if the interartiality always involves the intermediality, this proposal may not be reversed. First, we analyse a self-conscious investigation into digital art and technology. Prosospero's Books can be read as a daring visual essay that self-consciously investigates the technical and philosophical functions of letters, books, images, animated paintings, digital arts, and the other magical illusions, which have been modern or will be post-modern media to represent the world. Greenaway uses both conventional film techniques and the resources of high-definition television to layer image upon image, superimposing a second or third frame within his frame. Greenaway uses the frame-within-frame as the cinematic equivalent of Shakespeare's paly-within-play : it offer him the possibility to analyse the work of art/artist/spectator relationship. Secondly, we analyse the relationship between the written word, oral word and the books. Like the written word, the oral word changes into a visual image: The linguistic richness and nuances of Shakeaspeare's characters turn into the powerful and authoritative, but monotone, voices of Gielgud-Prospero, who speaks the Shakespearean lines aloud, shaping the characters so powerfully through his worlds that they are conjured before us. Specially each book is placed over the frame of the play's action, only partially covering the image, so that it gives virtually every frame at least two space-time orientations. Thirdly, we try to show how Peter Greenaway uses pictorial references in order to illustrate the context of the Renaissance as well as pictorial techniques and language in order to question the nature of artistic representation. For exemple, The storm is visualised through reference to Botticelli's : the storm of papers swirling around the library is constructed to look like a facsimili copy of Michelangelo's Laurentiana Library in Florence. Greenaway's modern mannerism consists in imposing his own aesthetic vision and his questioning of art beyond the play's meta-theatricality: in other words, Shakespeare''s text has been adapted without being betrayed.

비형식과학교육과 포괄적학습성과의 메타연구: 최근 10년간의 발표논문을 중심으로 (A meta-study of Informal Science Learning and Generic Learning Outcomes: Focusing on published papers in the last 10 years)

  • 조익형;유연우;나관식
    • 디지털융복합연구
    • /
    • 제19권9호
    • /
    • pp.33-42
    • /
    • 2021
  • 비공식적 환경에서의 과학 교육이 매우 중요함에도 불구하고 비형식 과학교육(ISL)과 그 영향에 대한 경향 분석 연구가 부족한 것이 현실이다. 이에 본 논문의 목적은 ISL의 교육적 효과와 활용 방안에 대해 알아보고, 향후 ISL 연구 방향에 대한 지침을 주는데 있다. 이 연구는 2010년부터 2019년까지 발표된 특정 ISL 관련 논문을 분류하고, 비형식 교육의 효과 측정에 사용되는 GLO의 각 요소와 비교 분석하였다. 분석된 자료는 SPSS, Chi-Square를 통해 부분별로 적합도를 확인했다. 결론적으로 연구자들은 'GLO'의 5가지 성과지표 중 '지식과 이해'와 '태도 및 가치'를 추구하기 위해 ISL을 활용하고 있는 것으로 나타났다. 반면에 '기술'과 '즐거움, 영감 및 창의성'에는 가장 적은 기대를 하는 것으로 나타나서, 향후 이러한 부분에서의 보완이 요구된다. 또한 이 연구를 통해 다양한 교육 종사자들에게 비형식 과학교육 관련 프로그램 개발과 향후 연구를 위한 방향을 제시하고자 한다.

척추 압박 골절 환자의 회복에 대한 침 치료의 유효성 및 안전성 평가: 체계적 문헌 고찰과 메타분석 (The Effectiveness and Safety of Acupuncture for Recovery of Patients with Vertebral Compression Fractures: A Systematic Review and Meta-analysis)

  • 배지민;이명수;최지원;양기영;김건형
    • Korean Journal of Acupuncture
    • /
    • 제36권1호
    • /
    • pp.1-18
    • /
    • 2019
  • Objectives : The purpose of this study was to evaluate the effectiveness and safety of acupuncture treatment for recovery of patients with vertebral compression fracture(VCF). Methods : We searched ten English and Chinese and seven Korean database up to April 2018. Randomised controlled trials(RCTs), quasi-RCTs, non-radomised Controlled Trials(CCTs) were eligible. Quasi-RCTs and CCTs were assessed only for safety assessment. Pain and adverse events were primary outcome of this review. Quality of life, dysfunction, patient satisfaction, incidence of new vertebral compression fracture were regarded as secondary outcomes. The risk of bias was assessed by two independent authors using the Cochrane risk of bias tool. Level of evidence was tabulated using the GRADE methods. Results : Of 1656 screened, 15 RCTs, 1 quasi-RCT and 3 CCTs were included. Number of participants per study ranged from 45 to 135. Most of the studies had unclear or high risk of bias and considerable heterogeneity in terms of type of intervention, comparison and time-points for outcome measurement. Compared to usual care alone, acupuncture combined with usual care showed short-term favorable results for pain relief in patients with VCF(5 studies, n=252, MD -1.05 point on a 0 to 10 point scale, 95% CI -1.45 to -0.65, $I^2=74%$). Four studies reported mild and temporary adverse events, and no serious adverse events were reported. One study descriptively reported that acupuncture was effective for improving quality of life without providing numerical outcomes. There were no reports of patient satisfaction and incidence of new VCF. Conclusions : Level of evidence is very low for the effectiveness and safety of acupuncture for pain, harms and other clinical outcomes in patients with VCF. Included studies suffered from incomplete reporting, high or unclear risk of bias and substantial heterogeneity between studies. Future high-quality RCTs are needed to assess whether acupuncture is beneficial for recovery of patients with VCF.