• 한국정보통신학회논문지
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• 제25권4호
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• pp.572-580
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• 2021

네트워크에서 전송지연을 줄이고 신뢰성을 높이기 위해 주로 고성능 및 고출력의 네트워크 장비를 사용하여 네트워크 품질을 보장하고 있다. 본 논문에서는 다수의 물리적 케이블로 이루어진 번들 링크를 가진 네트워크에서 트래픽 전송 시 소모되는 에너지를 최소화하기 위한 최적화 알고리즘을 제안한다. 제안된 최적화 알고리즘은 메타휴리스틱방식 중 하나인 타부서치 알고리즘을 적용하였으며, 각 트래픽에 대하여 소스 노드와 목적지 노드의 경로상에 있는 케이블을 최소로 선택하여 전송에너지가 최소화되도록 설계하였다. 제안된 최적화 알고리즘은 네트워크상의 모든 트래픽에 대하여 전송상에 사용되는 케이블의 수와 링크 효율 관점에서 성능평가가 수행되었으며, 성능평가 결과에서 이전에 제안된 방식보다 우수한 성능을 확인할 수 있었다.

• 생약학회지
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• 제52권1호
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• pp.1-12
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• 2021

Platycodon (Platycodon grandiflorum) is used as a food and medicinal ingredient worldwide, particularly in Northeast Asia. Although a large number of studies have been conducted to determine its medicinal efficacy, there is still a paucity of literature summarizing the clinical activity of Platycodon. In this systematic review, we aimed to summarize the clinical efficacy of Platycodon. All literature describing the clinical efficacy of Platycodon was collected from international databases, and relevant papers were carefully evaluated for eligibility. Data were extracted from the selected papers and quality evaluation was conducted in accordance with the standards provided by the National Institutes of Health (NIH), with all procedures being conducted in accordance with PRISMA 2009 checklist guidelines. After the removal of 342 papers, 644 studies were fully screened for their titles and abstracts, among which, 19 studies were finally selected for full summarization. Extraction of data indicated evidence of the effectiveness of Platycodon in the treatment of respiratory system-related diseases and cancer, and in the provision of immunity. However, we found that the quality and objectivity of evaluation, management of variable factors, sample size, and reproducibility were generally poor. Although Platycodon has shown potential antiviral, antibacterial, anticancer, and antidepressant effects, and promotion of immunity in clinical settings, it was not possible to integrate objective indicators to conduct a meta-analysis due to the lack of literature and insufficient studies. More investigations in the clinical setting should be conducted to confirm the functional effects of Platycodon.

• Imaging Science in Dentistry
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• 제52권4호
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• pp.333-342
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• 2022

Purpose: The goal of this systematic review was to compare the use of cone-beam computed tomography (CBCT) with that of computed tomography (CT) for volumetric evaluations of the tongue and oral cavity. Materials and Methods: A search for articles was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-analyses guidelines. The PubMed, Scopus, ScienceDirect, and SAGE Journals databases were searched for articles published between 2011 and 2021. Articles were screened and assessed for eligibility. Screening involved checking for duplication, reading the title and abstract, and reading the full text. Results: The initial search retrieved 25,780 articles. Application of the eligibility criteria yielded 16 articles for qualitative analysis. Multiple uses of CBCT were identified. In several studies, researchers assessed the volumetric correlation between tongue and oral cavity volumes, as well as other parameters. Post-treatment volumetric evaluations of the oral cavity were also reported, and the reliability of CBCT was assessed. The use of CT resembled that of CBCT. Conclusion: CBCT has been used in the evaluation of tongue and oral cavity volumes to assess correlations between those volumes and with the upper airway. It has also been used for volumetric evaluation after surgical and nonsurgical procedures and to assess the relationships between tongue volume, tooth position, occlusion, and body mass index. Participants with obstructive sleep apnea and malocclusion have been evaluated, and the reliability of CBCT has been assessed. In the included studies, CT was utilized for similar purposes as CBCT, but its reliability was not assessed.

• 대한한방내과학회지
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• 제44권3호
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• pp.285-293
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• 2023

Background: Irritable bowel syndrome (IBS) is a digestive disorder characterized by abdominal discomfort or pain accompanied by a change in stool condition. Owing to its complicated mechanisms, a standard treatment for IBS has not yet been established. Yukgunja-tang (YGT) is a Korean herbal medicine known in Asia to be effective in the treatment of gastrointestinal symptoms. In this study, we will conduct a systematic review of randomized controlled trials (RCTs) to assess the efficacy and safety of YGT in IBS treatment. Methods and analysis: English databases, such as Embase, Medline (via PubMed), Allied and Complementary Medicine Database, and Cochrane Central Register of Controlled Trials, will be searched for articles published up to April 2023. Additional databases, such as five Korean, one Chinese, and one Japanese database, will be included. RCTs and quasi-RCTs will also be included in the assessment of the efficacy of YGT. The overall efficacy rate will be the primary outcome, and data such as IBS quality-of-life measurements, global symptom scores, and adverse events will be the secondary outcomes. Review Manager Version 5.3 will be used for evaluation, and the risk of bias (RoB) will be evaluated using Cochrane Collaboration's RoB tool. The Grading of Recommendations Assessment, Development, and Evaluation approach will be used to score the quality of evidence. Conclusion: This study will demonstrate the efficacy and safety of YGT for treating patients with IBS.

• 한국광물학회지
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• 제32권4호
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• pp.259-271
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• 2019

채색 문화재 및 전통회화의 적색, 황색 안료로 사용되는 진사, 웅황, 그리고 자황의 광물학적 특성을 분석하고 촉진내후성 평가를 통한 안정성을 평가하였다. 진사는 시료명을 JB, JS로 하였고, 웅황과 자황은 각각 UH, JH로 하였다. 광물학적 특성 평가 결과 JB, JS는 cinnabar (HgS)로 주구성 광물이 확인되었고, 품위에 따른 화학성분에 차이를 보이지 않았다. UH와 JH는 각각 realgar (AsS), orpiment (As₂S₃)로 주구성 광물이 확인되었다. 편광현미경 관찰 결과 쪼개짐, 색상 등 편광학적 특성을 통해 모두 천연적으로 생성된 무기안료임을 알 수 있었다. 특히 진사의 경우 성분분석으로는 천연적으로 생성된 안료인지 인공안료인지 판별이 쉽지 않은데 편광현미경을 통해 천연안료가 가지는 입자특성 및 쪼개짐을 확인하였으며, 열적 반응 특성을 확인하였다. 열분석 결과 JH가 UH에 비해 유리전이 온도가 높고 안정한 것을 확인하였다. 촉진내후성 평가 결과 진사, 웅황 그리고 자황은 모두 광열화에 의한 색변화가 크게 나타나며, 진사는 최종적으로 흑색(blackening)되고 웅황과 자황은 밝은 노란색으로 변한다. Meta-cinnabar로 예상되는 JB가 cinnabar인 JS에 비해 흑화현상이 더 빨리 촉진되었으며, UH (realgar)는 광조사에 의해 arsenolite (As₂O₃)로 변하는 것을 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.515-521
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• 2013

Purpose: To evaluate the efficacy and toxicity of induction chemotherapy followed by concurrent chemoradiotherapy (the treatment group) versus concurrent chemoradiotherapy with or without adjuvant chemotherapy (the control group) for locoregionally advanced nasopharyngeal carcinoma. Methods: The search strategy included Pubmed, Embase, the Cochrane Library, China National Knowledge Internet Web, Chinese Biomedical Database and Wanfang Database. We also searched reference lists of articles and the volumes of abstracts of scientific meetings. All randomized controlled trials were included for a meta-analysis performed with RevMan 5.1.0. The Grading of Recommendations Assessment, Development, and Evaluation system (GRADE) was used to rate the level of evidence. Results: Eleven studies were included. Risk ratios of 0.99 (95%CI 0.72-1.36), 0.37 (95%CI 0.20-0.69), 1.08 (95%CI 0.84-1.38), 0.98 (95%CI 0.75-1.27) were observed for 3 years overall survival, 3 years progression-free survival, 2 years loco-regional failure-free survival and 2 years distant metastasis failure-free survival. There were no treatment-related deaths in either group in the 11 studies. Risk ratios of 1.90 (95%CI 1.24-2.92), 2.67 (95%CI 0.64-11.1), 1.04 (95%CI 0.79-1.37), 0.98 (95%CI 0.27-3.52) were found for grade 3-4 leukopenia, grade 3-4 thrombocytopenia, grade 3-4 mucous membrane, and grade 3-4 hepatic hematologic and gastrointestinal toxicity, the most significant toxicities for patients. Conclusion: Compared with the control group, induction chemotherapy followed by concurrent chemoradiotherapy was well tolerated but could not significantly improve prognosis in terms of overall survival, loco-regional failure-free survival or distant metastasis failure-free survival.

• 대한수학교육학회지:학교수학
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• 제13권4호
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• pp.651-674
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• 2011

함수적 사고는 학교 수학에서 가장 중요한 주제이고 함수적 사고 지도의 목적은 학생들의 함수적 사고를 향상시키는 것이라고 할 때 초등학교에서 함수적 사고를 지도한다는 것은 함수적 사고의 속성인 지정과 종속의 연관이 내재된 현상을 의미하는 함수적 사고이다. 함수적 사고를 습득했는지에 대한 평가 방법은 함수적 사고의 지도를 통해 학생들이 함수적 사고를 한다고 판단할 수 있는 학생들의 활동이다. 이를 위해서 교사는 함수적 속성을 갖는 타 교과의 내용과 관련된 함수적 상황의 형태의 전형적인 예(paradigm)을 제공하고, 적절한 발문을 통해 안내해야 한다. 본 연구의 목적은 타 교과와 연결된 상황 설정을 통한 함수적 사고의 지도 방안을 구안하고 적용하여 보다 발전된 지도 방안을 모색하는 것이다. 이를 위해 본 연구에서 제안하는 지도 방안은 함수적 상황의 준비단계, 적용단계, 반성단계의 3단계로 구성되며, 각 단계에서 지도해야 할 방안들을 제안하고자 한다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제21권5호
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• pp.413-429
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• 2021

Background: Migraine headaches are the second leading cause of disability worldwide and are responsible for significant morbidity, reduction in the quality of life, and loss of productivity on a global scale. The purpose of this systematic review and meta-analysis was to evaluate the efficacy of ketamine on migraines and other primary headache disorders compared to placebo and other active interventions, such as midazolam, metoclopramide/diphenhydramine, and prochlorperazine/diphenhydramine. Methods: An electronic search of databases published up to February 2021, including Medline via PubMed, EMBASE, Web of Science, and Cochrane Library, a hand search of the bibliographies of the included studies, as well as literature and systematic reviews found through the search was conducted to identify randomized controlled trials (RCTs) investigating ketamine in the treatment of migraine/headache disorders compared to the placebo. The authors assessed the risk of bias according to the Cochrane Handbook guidelines. Results: The initial search strategy yielded 398 unduplicated references, which were independently assessed by three review authors. After evaluation, this number was reduced to five RCTs (two unclear risk of bias and three high risk of bias). The total number of patients in all the studies was 193. Due to the high risk of bias, small sample size, heterogeneity of the outcomes reported, and heterogeneity of the comparison groups, the quality of the evidence was very low. One RCT reported that intranasal ketamine was superior to intranasal midazolam in improving the aura attack severity, but not duration, while another reported that intranasal ketamine was not superior to metoclopramide and diphenhydramine in reducing the headache severity. In one trial, subcutaneous ketamine was superior to saline in migraine severity reduction; however, intravenous (I.V.) ketamine was inferior to I.V. prochlorperazine and diphenhydramine in another study. Conclusion: Further double-blind controlled studies are needed to assess the efficacy of ketamine in treating acute and chronic refractory migraines and other primary headaches using intranasal and subcutaneous routes. These studies should include a long-term follow-up and different ketamine dosages in diagnosed patients following international standards for diagnosing headache/migraine.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제12권9호
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• pp.381-386
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• 2023

기존의 다양한 테스트 케이스 생성에 대한 연구는 모델로부터 테스트 케이스를 추출한다. 하지만 실무의 경우 자연어 요구사항 문장으로부터 테스트 케이스를 생성할 수 있어야 한다. 이를 위해 자연어 문장의 분석하고, 분석 과정 및 결과를 요구공학 영역에 접목하는 연구는 매우 필요하다. 하지만 한국어 문장의 다양성 때문에, 한국어 자연어 요구사항 분석은 어려운 이슈이다. 우리는 한국어 자연어 요구사항으로부터 테스트 케이스 생성 연구 중 하나로써, 자연어 요구사항의 정의 분석, C3Tree 모델의 생성, 원인-결과 그래프의 생성, 결정 테이블의 생성 단계를 통한 테스트 케이스 생성 방법을 연구한다. 본 논문은 중단 단계로써, 메타모델링 변환 기법을 이용하여 C3Tree 모델 기반의 결정 테이블로부터 테스트 케이스 생성 방법을 제안한다. 이 방법은 모델 변환 규칙의 수정을 통해 모델 to 모델, 모델 to 텍스트로의 변환 과정을 제어한다. 모델이 변형되거나, 새로운 모델이 추가되더라도 프로그램 알고리즘의 직접적인 수정 없이 모델 변환 규칙을 유지보수 할 수 있다. 평가 결과, 결정 테이블에 대한 모든 조합이 테스트 케이스로 자동 생성되었다.