• Investigative Magnetic Resonance Imaging
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• 제24권3호
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• pp.174-177
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• 2020

Multiple studies have established that mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) exhibits reversible diffusion restriction in the white matter, including the splenium. There have been a few previous reports of the change in fractional anisotropy (FA) of MERS cases. Herein, we report the longitudinal changes in axial and radial diffusivity (AD and RD), and FA in a 15-year-old boy patient with MERS. Our case demonstrated that a MERS lesion had a significant drop of AD in the early period and gradual recovery. On the contrary, RD did not show any significant change.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2020년도 추계학술발표대회
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• pp.757-758
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• 2020

국가적 차원에서 MERS 와 같은 재난을 잘 대처하기 위해서는 기존의 대응 네트워크를 분석할 필요가 있다. 본 논문에서는 2015 년 대한민국에서 일어난 MERS 대응 네트워크를 커뮤니티 탐지 기법을 이용하여 네트워크를 분석한다. 커뮤니티 탐지 기법은 네트워크 분석방법 중 하나로 이 기법을 통해 MERS 대응 네트워크에서 유사한 역할을 수행하는 기관들끼리 그룹핑 할 수 있다. 또한 기관들을 그룹핑 한 결과와 각 기관의 지리적인 정보를 활용하여 전국적으로 기관들이 어떻게 분포되어 있는지 살펴본다.

• 대한한방내과학회지
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• 제36권3호
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• pp.335-347
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• 2015

Objectives This study aims to overview traditional Chinese medicine (TCM) treatment guidelines for severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) in order to facilitate the use of Korean medicine (KM) treatment in pandemic diseases. Methods We compared the characteristics between SARS and MERS, and overviewed the Traditional Chinese Medicine treatment guidelines for SARS and MERS. We assessed the efficacy of simultaneous administration of herbal medicine and Western medicine on SARS by studying Cochranes 2012's Systematic Review Studies. Results and Conclusions Based on wen bing (warm diseases) of KM as well as TCM, KM treatment can be an alternative for pandemic diseases such as SARS and MERS considering the Korean's characteristic environment.

• 한국직업건강간호학회지
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• 제25권1호
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• pp.1-8
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• 2016

Purpose: The 2015 Korean Middle East Respiratory Syndrome Coronavirus (MERS-CoV) outbreaks resulted in 186 cases, with 8% (15 persons) of these being nurses. This study aimed to examine MERS-CoV infection status of clinical nurses and to evaluate perception for infection control. Methods: We investigated the MERS-CoV infection status of nurses using MERS-CoV press release data. We examined and analysed perception for Infection control of 121 nurses of the three MERS intensive therapeutic hospitals in July 2015. Results: One to six nurses per hospital in total 8 health care facilities were infected with MERS-CoV. They mainly had short clinical careers and were unaware of infection possibility. The personal and organizational infection control levels that nurses perceive were low and the relationship between two levels was statistically significant. Conclusion: For promoting health protection and infectious disease management competency of nurses, it is necessary to prepare institutional system for controlling infectious disease.

• 보건교육건강증진학회지
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• 제32권3호
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• pp.1-9
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• 2015

Objectives: The purpose of this article was to assess epidemiological characteristics and recommendations for strengthening national response and preparedness after MERS-CoV outbreak in Korea, 2015. Methods: The author reviewed epidemiological reports and policy recommendations on MERS-CoV outbreak in Korea, 2015. Results: There was no evidence that genetical difference between the MERS viruses in the Republic of Korea and recent viruses in the Middle East. From the index case to last laboratory-confirmed case, there were 186 laboratory-confirmed cases that included 36 deaths(19.4%), all of whom appear epidemiologically linked to the index cases or subsequent secondary, tertiary, and quaternary cases. This outbreak spread to hospitals through nosocomial transmission. At least, three large clusters were investigated. However, there was at least one case of community transmission of MERS-CoV. Several factors had contributed to the MERS outbreak in Korea, 2015 that including epidemiological characteristics, and infrastructure of national healthcare system for preventing and controlling emerging infectious diseases. Conclusions: It is very important that to share experiences and identify underlying causes of this outbreak for prevention and control of emerging infectious disease in the future; including epidemiology, clinical features, and public health response and preparedness.

• 약학회지
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• 제59권6호
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• pp.245-250
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• 2015

Middle East respiratory syndrome - coronavirus infection has posed substantial threat to public health with extremely high mortality rate in 2015. Although there are no approved novel medications for coronavirus, several antiviral agents such as ribavirin and interferon have been tried to MERS patients according to the in-vitro inhibitory effect, therapeutic effect on the animal model and experience from the severe acute respiratory syndrome - coronavirus infection. The aim of this study is to evaluate the clinical evidence of the antiviral treatment for MERS-CoV infection. After systematically searching the medical literature databases, I found five studies described the clinical efficacy of antiviral treatment on MERS patients. All of them were about the combination therapy of ribavirin and interferon (IFN). Two of them were retrospective cohort studies with quality of evidence (QOE) II and the others were observational study and case reports with QOE III. As a result of critical appraisal, it is concluded that none of those studies represented confirmatory clinical evidence of the efficacy of ribavirin and interferon combination therapy on MERS patients. Although Omrani et al. represented that ribavirin and IFN treatment had significantly improved survival at 14 days, it was not enough time to conclude the effect.

• 임상간호연구
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• 제23권2호
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• pp.179-188
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• 2017

Purpose: This study examined post-traumatic stress (PTS) and the factors affecting it among general hospital nurses after the MERS(Middle East Respiratory Syndrome) epidemic. Methods: Data were collected from 170 nurses who worked at general hospitals since the first reported MERS outbreak. The IES-R-K assessed PTS. Data were analyzed using SPSS. Results: The mean PTS level was 7.80 points (range: 0~88); 7.1% of the participants were at a high risk. Nurses who had been in contact with patients suspected or diagnosed with MERS had high post-traumatic levels; those who had been quarantined during the MERS outbreak had relatively higher PTS levels. Shift-work nurses had higher PTS levels than those with fixed working hours. Above charge' nurses stress levels were higher than staff nurses' stress levels. The results showed that factors including contact with an MERS-suspected or diagnosed patient, position at work, and working status of MERS-affected nurses explained 16% of the PTS. Among the main variables, nurses' above charge position was the greatest factor affecting PTS. Discussion: It is necessary to develop intervention studies and programs considering these variables. Furthermore, development and implementation of differentiated programs should be done considering the position of above charge nurses.

• Kidney Research and Clinical Practice
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• 제36권2호
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• pp.111-116
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• 2017

The Korean Society of Nephrology participated in the task force team consisting of government authorities and civilian experts to prevent and control the spread of Middle East respiratory syndrome (MERS) in 2015. The Korean Society of Nephrology MERS Task Force Team took an immediate action and drafted 'the clinical recommendation for hemodialysis facilities' to follow when the first and the only confirmed case was reported in the hemodialysis unit. Owing to the dedicated support from medical doctors, dialysis nurses, and related medical companies, we could prevent further transmission of MERS infection successfully in hemodialysis units. This special report describes the experience of infection control during MERS outbreak in 2015 and summarizes the contents of 'the clinical practice guideline for hemodialysis facilities dealing with MERS patients' built upon our previous experience.

• 한국산학기술학회논문지
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• 제21권5호
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• pp.401-408
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• 2020

본 연구는 응급구조(학)을 전공하는 학생들의 메르스에 관한 지식, 태도 및 예방행위와의 관계를 파악하여 메르스 예방교육에 대한 기초자료를 제공하고자 하였다. 연구방법은 2019년 11월 8일부터 2019년 11월 30일까지 P시 3년제 대학 응급구조과에 재학 중인 167명을 대상으로 하였고, 연구도구는 구조화된 설문지를 이용하였다. 연구결과는 SPSS/WIN 23.0을 사용하여 분석하였다. 대상자의 메르스 교육 경험은 경험자 74명(44.3%), 비 경험자 93명(55.7%)으로 경험하지 않은 대상자가 많은 것으로 나타났으며, 메르스에 관한 태도 항목에서는 '메르스 환자를 다룰 때는 반드시 개인보호장비를 착용해야 한다'에서 평균 4.54±0.87로 높게 나타났으며, 메르스에 관한 예방행위항목에서는 '평소보다 더 자주 손을 씻었다'에서 평균 3.82±1.06으로 높게 나타났다. 메르스에 대한 상관관계분석 결과 '친구 모임, 외식, 스포츠 관람, 쇼핑 등을 취소하거나 미루었다' 한 항목에서 r=-.63, p<.004로 음(-)의 상관관계를 제외하고 모두 태도가 높을수록 예방행위 수준이 높았다. 따라서 본 연구의 결과를 토대로 메르스에 대한 교육수준 및 지식수준을 향상시킬 수 있는 교육 프로그램의 개발이 필요하며, 메르스에 대한 체계적이고 반복적인 교육이 필요하다고 사료된다.

• 한국콘텐츠학회논문지
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• 제17권11호
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• pp.515-524
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• 2017

본 연구는 전염병이 관광산업의 경영성과에 미치는 영향을 분석하기 위해 메르스 발생 전후 호텔업, 여행업, 항공업의 경영성과에 차이가 있는가를 분석하였다. 분석결과 호텔업의 경우 수익성 지표인 매출액세전 순이익률과 매출액영업이익률이 메르스 발생 전후 통계적으로 유의적인 차이가 있는 것으로 나타났는데 두 변수 모두 메르스 발생 이후 낮아진 것으로 나타났다. 여행업의 경우 안정성지표인 부채비율과 차입금의존도가 메르스 발생 전후 통계적으로 유의적인 차이가 있는 것으로 나타났으며 두 변수 모두 메르스 발생이후 높아진 것으로 나타났다. 또한 활동성지표 중 재고자산회전율이 메르스 발생이후 낮아진 것으로 나타났다. 항공업의 경우 수익성지표 중 매출액영업이익률이 메르스 발생 이후 약간 높아졌으며 활동성 지표 중 총자산회전율이 메르스 발생이후 낮아진 것으로 나타나 통계적으로 유의적인 차이가 있었다. 따라서 관광산업의 경영자는 업종의 특성에 맞게 전염병에 대한 부정적 인식을 완화할 수 있는 마케팅 전략의 수립 등 적극적인 대처 방안을 모색해야 한다.