• Title/Summary/Keyword: Menopausal status

Search Result 198, Processing Time 0.025 seconds

Correlations between the Fatty Acid Composition of Serum Phospholipids and Blood Pressure

  • Lee, Yang-Cha-Kim;Shim, Yoo-Jin;Chung, Eun-Jung;Kim, Soo-Yeon;Yangsoo Jang;Lee, Jong-Ho
    • Nutritional Sciences
    • /
    • v.5 no.2
    • /
    • pp.68-74
    • /
    • 2002
  • Studies of the relationship between the composition of serum fatty acids and blood pressure are complex and controversial. Fatty acids, important constituents of biological membranes, could potentially affect vasoreactivities including blood pressure. In this study the compositions of fatty acids in serum phospholipids were compared between three types of hypertensive subjects (men, pre-menopausal women, and post-menopausal women) and their respective nrmotensive controls. Serum lipids were extracted and phospholipids were separated by thin layer chromatography. The percentage of palmitic acid (16 : 0) in serum phospholipids was significantly higher and the percentage of stearic acid (18 : 0) was significantly lower in all three hypertensive groups, compared with their corresponding control groups. Only in the group of post-menopausal women, palmitic acid was closely associated wish increases in both systolic (SBP) and diastolic blood pressure (DBP), while stearic acid was associated with decreases in both SBP and DBP. The polyunsaturated fatty acids in serum phospholipids behaved differently from saturated fatty acids. The ratios of products / precursor fatty acids, such as $\sumLCPUFA\omega6/18 : 2\omega$6, 20 : 4$\omega$6/18 : 2$\omega$6, ∑LCPUFA$\omega$3/18 : 3$\omega$3 and 22 : 6$\omega$3/20 : 5$\omega$3, were all clearly associated with both SBP and DBP in hypertensive, post-menopausal women. Desaturation and elongation in fatty acid metabolism could affect the bioavailability of eicosanoid precursors. Changes in the constituent fatty acids of phospholipids and eicosanoid precursors may also influence fluidity, ionic transport, hormone receptors and enzyme activities in biological membranes. In conclusion, both systolic and diastolic blood pressure in post-menopausal women was positively associated with the level of palmitic acid, and negatively associated with the level of stearic acid, in serum phospholipids. The relationships between serum phospholipid-$\omega$6 and $\omega$3 series fatty acids and blood pressure in women, especially in post-menopausal women, require further investigation by taking into consideration hormonal status and eicosanoid metabolism. Funker study is needed to determine the value of dietary manipulation of fatty acid constituents of serum phospholipids, relating to hypertension in women.

Health status of menopausal women and correlates

  • Kannur, Deepa;Itagi, Sunanda
    • The Korean Journal of Food & Health Convergence
    • /
    • v.4 no.1
    • /
    • pp.1-13
    • /
    • 2018
  • The health status of menopause and its correlates among middle aged 160 rural and urban women was studied during 2015. The women who attained menopause and belonging to 40-55 years age range were selected from 8 villages of 4 talukas of Dharwad and Bagalkot Districts. The health status of women was evaluated by using standardized questionnaire, Post Graduate Institute of Medical Education and Research (PGI). The structured interview schedule was used to collect personal information like name of the family members with their age, relationship with respondent. The Socio Economic Status (SES) of family was assessed by using Socio Economic Status scale developed by Agarwal (2005). The results revealed that 53.75 per cent respondents shown moderately affected followed by 26.25 per cent mildly affected and 20 per cent of women indicated severely affected health status. The mean value of health status in rural women is higher ($23.67{\pm}7.02$) than mean value of ($21.50{\pm}6.89$) urban women means the rural women had more health problems than urban women. Health status were high negatively significantly related with SES, education and occupation means women belonged to better SES category, literate and working women experienced less health problems compared to women who had poor SES, illiterate and non-working.

A Study on the Relationship between Nutritional Status and Select Blood Parameters in Premenopausal and Postmenopausal Women (폐경 전.후 여성의 식습관과 영양 섭취 상태 및 일부 혈액지표와의 관계 연구)

  • Kim, Sung-Hwan;Kim, Na-Young;Yeo, In-Seob
    • Journal of the East Asian Society of Dietary Life
    • /
    • v.17 no.4
    • /
    • pp.483-489
    • /
    • 2007
  • This study was performed to investigate dietary habits, and to evaluate the relationship between nutritional status and certain blood parameters in premenopausal and postmenopausal women living in Daejeon. Adult Korean females(n=110) that had visited the Health Promotion Center of Eulji University Hospital were analyzed. We examined blood parameters, body composition, and life style factors such as food habits and physical activity in pre- and post-menopausal women. The collected data were then analyzed to evaluate the various items. Overall, there were no differences between the pre- and post-menopausal women for food habit score, or for intakes of energy, protein, Int, iron, vitamin A, vitamin $B_1$, vitamin $B_2$, niacin, vitamin C, and calcium. However, carbohydrate intake was significantly higher in the postmenopausal women than in the premenopausal women. The Dietary Reference Intakes for Koreans(KDRIs), in terms of energy, fat, calcium, vitamin A and vitamin $B_1$, were less than 100% in both the premenopausal women and postmenopausal women. All intakes of protein, iron, vitamin $B_2$, niacin, and vitamin C satisfied the KDRIs in both groups. Finally, the postmenopausal women had higher serum fasting blood glucose, total cholesterol, LDL-cholesterol and alkaline phosphatase levels than the premenopausal women.

  • PDF

Study on Soy Isoflavone Consumption and Risk of Breast Cancer and Survival

  • Kang, Hong-Bin;Zhang, Ya-Feng;Yang, Jin-Dun;Lu, Kuan-Liang
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.3
    • /
    • pp.995-998
    • /
    • 2012
  • Aim: Isoflavones in soy foods are part of a larger class of flayonoid compounds that have have been demonstrated to be potent dietary anti-cancer agents, and the effect of soy intake on the survival of ovarian cancer is conflicting. Therefore, we aimed to explore the whether soy intake is related to the risk of death of breast cancer. Methods: A prospective study was conducted. A total of 256 patients included in this study had breast cancer and were recruited between January 2004 and January 2006. All of them were followed up from since January 2011. A univariate Cox's regression analysis was used to assess the association between soy intake and survival. Results: The education level, menopausal status, ER/PR status and TNM stage were significant difference in the survival of breast cancer. The highest soy isoflavone was associated with a decreased death risk of breast cancer (OR=0.25, 95% CI=0.09-0.54). Moreover, the higher consumption of soy protein also presented a trend decreased breast cancer risk, and the highest consumption significantly reduced the cancer risk compared with the lowest consumption (OR=0.38, 95% CI=0.17-0.86). Conclusion: The present study suggests soy intake is associated with a significant reduced death risk of breast cancer in Chinese population. Further large sample studies are warranted to confirm the inverse association of soy consumption and breast cancer survival by menopausal status.

Obesity related Factors in Middle Aged Women: Comparison of Body Mass Index and/or Waist Circumference as Measures of Obesity (지역사회 중년여성의 특성 및 건강행위 실천과 비만: 비만 지표에 따른 비교)

  • Kim, Gwang-Suk;Kim, Eun-Gyeong;Lee, Chung-Yul;You, Mi-Ae;Klm, Bong-Jeong;Park, So-Hyun;Lee, Soon-Nam;Klm, Jeong-Eun
    • Journal of Korean Public Health Nursing
    • /
    • v.23 no.2
    • /
    • pp.273-284
    • /
    • 2009
  • Purpose: The study examined obesity conditions and related factors in middle aged Korean women who had been diagnosed as obese based body mass index (BMI) or waist circumference (WC) measurement. Presently, BMI alone, WC alone, or BMI + WC were used as obesity measures. Methods: Subjects were 488 women 40~64 years of age living in one city, Korea. Structured questionnaires concerning general characteristics, health behavior practices, and chronic disease history were completed by each subject. Results: The proportions of obesity were 42.4% by BMI, 39.3% by WC, and 51.3% by the combination of both measurements. Chi-square test revealed significant associations of obesity with age, education level, menopausal status, frequency of excessive eating, and history of diabetes mellitus or hypertension. These associations were similar for the three measurement schemes. There was significant positive relationship between BMI and WC, whereas the relationship between BMI and WHR (waist-hip ratio) was not significant. Conclusions: The combination of BMI and WC measurement may be a valid way to evaluate the obesity status in middle-aged women. Developing an obesity management program that includes control of excessive eating, and consideration of menopausal status and history of chronic diseases would be prudent.

A Model for Health Promoting Behaviors in Late-middle Aged Woman (중년후기 여성의 건강증진행위 모형구축)

  • Park, Chai-Soon
    • Women's Health Nursing
    • /
    • v.2 no.2
    • /
    • pp.298-331
    • /
    • 1996
  • Recent improvements in living standard and development in medical care led to an increased interest in life expectancy and personal health, and also led to a more demand for higher quality of life. Thus, the problem of women's health draw a fresh interest nowadays. Since late-middle aged women experience various physical and socio-psychological changes and tend to have chronic illnesses, these women have to take initiatives for their health control by realizing their own responsibility. The basic elements for a healthy life of these women are understanding of their physical and psychological changes and acceptance of these changes. Health promoting behaviors of an individual or a group are actions toward increasing the level of well-being and self-actualization, and are affected by various variables. In Pender's health promoting model, variables are categorized into cognitive factors(individual perceptions), modifying factors, and variables affecting the likelihood for actions, and the model assumes the health promoting behaviors are affected by cognitive factors which are again affected by demographic factors. Since Pender's model was proposed based on a tool broad conceptual frame, many studies done afterwards have included only a limited number of variables of Pender's model. Furthermore, Pender's model did not precisely explain the possibilities of direct and indirect paths effects. The objectives of this study are to evaluate Pender's model and thus propose a model that explains health promoting behaviors among late-middle aged women in order to facilitate nursing intervention for this group of population. The hypothetical model was developed based on the Pender's health promoting model and the findings from past studies on women's health. Data were collected by self-reported questionnaires from 417 women living in Seoul, between July and November 1994. Questionnaires were developed based on instruments of Walker and others' health promotion lifestyle profile, Wallston and others' multidimensional health locus of control, Maoz's menopausal symptom check list and Speake and others' health self-rating scale. IN addition, items measuring self-efficacy were made by the present author based on past studies. In a pretest, the questionnaire items were reliable with Cronbach's alpha ranging from .786 to .934. The models for health promoting behaviors were tested by using structural equation modelling technique with LISREL 7.20. The results were summarized as follows : 1. The overall fit of the hypothetical model to the data was good (chi-square=4.42, df=5, p=.490, GFI=.995, AGFI=.962, RMSR=.024). 2. Paths of the model were modified by considering both its theoretical implication and statistical significance of the parameter estimates. Compared to the hypothetical model, the revised model has become parsimonious and had a better fit to the data (chi-square =4.55, df=6, p=.602, GFI=.995, AGFI=.967, RMSR=.024). 3. The results of statistical testing were as follows : 1) Family function internal health locus of control, self-efficacy, and education level exerted significant effects on health promoting behaviors(${\gamma}_{43}$=.272, T=3.714; ${\beta}_[41}$=.211, T=2.797; ${\beta}_{42}$=.199, T=2.717; ${\gamma}_{41}$=.136, T=1.986). The effect of economic status, physical menopausal symptoms, and perceived health status on health promoting behavior were insignificant(${\gamma}_{42}$=.095, T=1.456; ${\gamma}_{44}$=.101, T=1.143; ${\gamma}_{43}$=.082, T=.967). 2) Family function had a significance direct effect on internal health locus of control (${\gamma}_{13}$=.307, T=3.784). The direct effect of education level on internal health locus of control was insignificant(${\gamma}_{11}$=-.006, T=-.081). 3) The directs effects of family functions & internal health locus of control on self-efficacy were significant(${\gamma}_{23}$=.208, T=2.607; ${\beta}_{21}$=.191, T=2.2693). But education level and economic status did not exert a significant effect on self-efficacy(${\gamma}_{21}$=.137, T=1.814; ${\beta}_{22}$=.137, T=1.814; ${\gamma}_{22}$=.112, T=1.499). 4) Education level had a direct and positive effect on perceived health status, but physical menopausal symptoms had a negative effect on perceived health status and these effects were all significant(${\gamma}_{31}$=.171, T=2.496; ${\gamma}_{34}$=.524, T=-7.120). Internal health locus and self-efficacy had an insignificant direct effect on perceived health status(${\beta}_{31}$=.028, T=.363; ${\beta}_{32}$=.041, T=.557). 5) All predictive variables of health promoting behaviors explained 51.8% of the total variance in the model. The above findings show that health promoting behaviors are explained by personal, environmental and perceptual factors : family function, internal health locus of control, self-efficacy, and education level had stronger effects on health promoting behaviors than predictors in the model. A significant effect of family function on health promoting behaviors reflects an important role of the Korean late-middle aged women in family relationships. Therefore, health professionals first need to have a proper evaluation of family function in order to reflect the family function style into nursing interventions and development of strategies. These interventions and strategies will enhance internal health locus of control and self-efficacy for promoting health behaviors. Possible strategies include management of health promoting programs, use of a health information booklets, and individual health counseling, which will enhance internal health locus of control and self-efficacy of the late-middle aged women by making them aware of health responsibilities and value for oneself. In this study, an insignificant effect of physical menopausal symptoms and perceived health status on health promoting behaviors implies that they are not motive factors for health promoting behaviors. Further analytic researches are required to clarify the influence of physical menopausal symptoms and perceived health status on health promoting behaviors with-middle aged women.

  • PDF

An Objective Evaluation on Menopausal Syndrome and the Effect of Red Ginseng

  • Katsutaro Nagata;Katsuya Morishita;Kotaro Fujioka;Misako Yamazaki;Akihiro Okamoto;Kenji Kubota
    • Proceedings of the Ginseng society Conference
    • /
    • 1998.06a
    • /
    • pp.322-326
    • /
    • 1998
  • In order to evaluate menopausal syndrome objectively, examinations were performed as follows: 1) Simplified Menopausal Index (SMI Koyama) and QOL questionnaire (Nagata) were examined subjectively. 2) Urine 17-KS-5 (S Nishikaze), 17-OHCS (OH) were examined objectively. 3) A mobile telemedical device with EKG and KSG was lent to Patients. The subjects were 48 menopausal patients who visited our university hospital as outpatients. According to the results of 5, OH, the subjects were divided into 4 Groups; Group I is high S & high OH, Group ll low S & low OH, Group 111 is low S & high OH, Group tl is high S & low OH. Group IH was the largest (64.6%), Group of was none. The subjects showed significantly lower QOL condition and higher score of SMI. In the QOL, questionnaire items of fixation to physical status (psychogenic reaction), sleep (insomnia), pain(chronic pain) were in common. In SMI, functional vascular symptoms were the largest number. On treatment, Group I was considered to have no need for supplementary agents, but anti-Oketsu agents was prescribed. For Group ll and in some supplementary agents such as red ginseng were prescribed, because they showed low 5. In conclusion, all the groups showed a sign- nificant improvement of QOL and SMI. Group I showed a decrease of OH, Group ll showed an increase of 5, Group In showed an increase of S and SIOH and a decrease of OH. These phenomena were considered prohomeostatic. In QOL, the items of chronic pain, insomnia and appetite were improved. In SMI, chillness, dyspnea, palpitation, pain and fatigability were improved. In mobile tole-medical device, abnormal findings were found in 88.2% of patients. General sdaptation syndrome (Selye, H.) is considered to adjust human life. Menopause is the transit period to exhausted stage in it. So its symptoms vary from person to person. In conclusion, 5 and OH are useful both for classification of menopausal syndrome and for determining treatments according to the classification

  • PDF

A Study on the Experts' Agreement on the Patterns Classification of the Prescription for the Use of Menopausal Disorder (갱년기장애 사용처방과 변증분류에 관한 전문가 합의 연구)

  • Jeon, Soo-Hyung;Park, Young-Hee;Kim, Jong-Won;Chi, Gyoo-Yong;Lee, Ji-Yeon;Lee, In-Seon
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.35 no.2
    • /
    • pp.70-86
    • /
    • 2022
  • Objectives: This study attempted to provide prescriptions that can be used according to the classification of menopausal disorders in order to increase the clinical utilization of CaPSPI (Diagnostic System for Climacteric and Postmenopausal Syndrome Pattern Identification). Methods: Delphi method survey was conducted for expert consensus on the Pattern Identification that could be used for each prescription by selecting frequent prescriptions based on the literature researched on the prescription of Korean medicine used for women with menopausal disorders. 11 experts participated in the questionnaire for posterity and 7 experts for sasang constitution. The survey was divided into the main prescription that can be mainly used for the patterns and the minor prescription that can be used although the suitability is somewhat low. Expert consensus was obtained through the second survey, and the pattern classification of prescriptions that were not confirmed here was confirmed through a face-to-face meeting. Results: There were 56 prescriptions mainly used for treatment for menopause, 45 for posterity and 11 for Sasang constitution. There were 69 identifications of 45 posterity prescriptions and 17 classifications of 11 Sasang constitutional prescriptions including major and minor patterns. By pattern identifications, the number of major/minor prescriptions was as follows. 肝鬱 14/5, 腎陰虛 8/2, 腎陽虛 4/1, 肝腎陰虛 2/7, 腎陰陽兩虛 3/1, 心腎不交 6/3, 心脾兩虛 15/2, 心火 7/6. Conclusions: In the future, by accumulating and analyzing the data on the diagnosis and treatment using CaPSPI, the clinical status of Korean medicine for menopausal disorders can be reviewed, and it can be used as the basis for the clinical practice guidelines for menopausal disorders. In addition, it is thought that analyzing the results of the diagnosis of pattern identifications and the prescription of Sasang constitution can be helpful in research on the posterity and Sasang constitution.

The Prevalence and Associated Factors of the Metabolic Syndrome in Pre-menopausal Housewives: An Analysis of the 2010~2015 Korean National Health and Nutrition Examination Survey (폐경 전 전업주부의 대사증후군 관련 요인: 2010~2015년 국민건강영양조사자료분석)

  • Kim, Chul-Gyu;Kim, Youngji
    • Research in Community and Public Health Nursing
    • /
    • v.29 no.1
    • /
    • pp.108-119
    • /
    • 2018
  • Purpose: The purpose of this study is to estimate the prevalence of the metabolic syndrome in pre-menopausal housewives and to explore controllable and uncontrollable factors regarding metabolic syndrome. Methods: The study population of this cross-sectional survey was from the Korean Health and Nutrition Examination Survey (KHANES) 2010 through 2015, including the fifth and sixth population-based studies. The criteria for metabolic syndrome include waist circumference, blood pressure, fasting plasma glucose, triglyceride, high-density lipoprotein (HDL) based on Korean Clinical Practice Guideline for Metabolic Syndrome by the Korean Academy of Family Medicine 2015. Results: Among the 2,498 subjects, 247 subjects had metabolic syndrome and the prevalence was estimated to be 9.9%. The number of subjects who met the criterion of HDL was 936 (36.2%), which was the most prevalent among the criteria for metabolic syndrome. Statistically significant (p<.05) factors include age, livinghood benefit group, perceived health status, obesity, family history of DM, sleeping time, awareness of stress,leukocyte, and erythrocyte count. The odds ratio of obesity in the BMI ${\geq}25$ group was 12.59 times as high as that of the BMI <25 group (p<.001) for metabolic syndrome. Conclusion: The prevalence of metabolic syndrome in pre-menopausal housewives in the survey was not low, and it is necessary to develop and apply comprehensive health habit management programs to improve controllable factors including exercise and food intake.