• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.3
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• pp.684-692
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• 2003

The herbal extract(YMT_02) is a modified extracts from Yukmijihwang-tang(YMJ) to promote memory-enhancing. The YMJ extracts has been widely used as replenishing yin and tonifying the kidneys herbal medicine for hundred years ia Asian countries. The purpose of this study is to: 1) quantitatively evaluate the memory-enhancing effect of YMT_02 by passive avoidance test, 2) statistical evaluation of candidate gene expression (pentraxin. PEP-19, transthyretin) in rat hippocampus. The hippocampi of YMT_02 and control group were dissected and mRNA was further purified. After synthesizing cDNA using oligo-dT primer, the cDNA were applied to Real Time PCR. The results were as follows : 1) passive avoidance test showed enhancing memory retentin by YMT_02 treatment, 2) expression of pentraxin, that accelerate degenerating of neuronal cell, was significantly decreased, 3) the mRNA of genes that has been known to be associated with protecting neuronal cell degeneration, such as PEP-19 and transthyretin, were significantly increased upon YMT_02 treatment. From above results, the administration of YMT_02 which tonify the function of Kidneys could enhance the ability of memory and learning. In addition, the administration of YMT_02 enhance memory retention through modulating particular gene (pentraxin, PEP-19, transthyretin) expressions in hippocampu.

• The Journal of Pediatrics of Korean Medicine
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• v.13 no.2
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• pp.93-110
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• 1999

The intelligence is the capacity to recognize the things and implies the meaning of abstract thought, learning and adaptability to the circumstance. Recently, as the promotion of learning ablility and memory attracts many people's attention, many studies of this have been accomplished but the pharmacological methods could not promote the intelligence and memory. In oriental medical theory, the human body is composed of four elements - essence, energy, sprit, blood and among these elements, sprit is considered as the concept of vital energy and mind. Especially, from the Jang-Fu physiological point of view, the memory is closly related with the heart and kidney In oriental medicine, some experiments on animal and literature studies on the subject of memory promotion have done. But because of difference in memory mechanism between man and animal, it is not in reason to apply the result of experiment on animal to human. Therefore I have methodological study of memory promotion to set up the concept of oriental medicine and experimental theory about this and can obtain such conclusion. 1. The oriental medical therapy for memory promotion is following. nourishing the heart and blood, regulating the function of spleen, relieving the mental stress, reinforcing the heart and kidney, invigorating and enriching the blood. 2. The insufficient intelligence in a child is considered to not be full and in an old man, it is considered to decline by degrees. 3. It is needed to molecular biological study of neurotransmitter after the using of oriental medical therapy. 4. It is possible to study using the genetic mutation or observing the collateral of brain nerve cell.

• Research in Vestibular Science
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• v.17 no.4
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• pp.134-141
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• 2018

Objectives: We aimed to study the role of vestibular input on spatial memory performance in mice that had undergone bilateral surgical labyrinthectomy, semicircular canal (SCC) occlusion and 4G hypergravity exposure. Methods: Twelve to 16 weeks old ICR mice (n=30) were used for the experiment. The experimental group divided into 3 groups. One group had undergone bilateral chemical labyrinthectomy, and the other group had performed SCC occlusion surgery, and the last group was exposed to 4G hypergravity for 2 weeks. The movement of mice was recorded using camera in Y maze which had 3 radial arms (35 cm long, 7 cm high, 10 cm wide). We counted the number of visiting arms and analyzed the information of arm selection using program we developed before and after procedure. Results: The bilateral labyrinthectomy group which semicircular canal and otolithic function was impaired showed low behavioral performance and spacial memory. The semicircular canal occlusion with $CO_2$ laser group which only semicircular canal function was impaired showed no difference in performance activity and spatial memory. However the hypergravity exposure group in which only otolithic function impaired showed spatial memory function was affected but the behavioral performance was spared. The impairment of spatial memory recovered after a few days after exposure in hypergravity group. Conclusions: This spatial memory function was affected by bilateral vestibular loss. Space-related information processing seems to be determined by otolithic organ information rather than semicircular canals. Due to otolithic function impairment, spatial learning was impaired after exposure to gravity changes in animals and this impaired performance was compensated after normal gravity exposure.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.3
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• pp.837-852
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• 2021

Recurrent neural network (RNN) architectures have been used for language modeling (LM) tasks that require learning long-range word or character sequences. However, the RNN architecture is still suffered from unstable gradients on long-range sequences. To address the issue of long-range sequences, an attention mechanism has been used, showing state-of-the-art (SOTA) performance in all LM tasks. A differentiable neural computer (DNC) is a deep learning architecture using an attention mechanism. The DNC architecture is a neural network augmented with a content-addressable external memory. However, in the write operation, some information unrelated to the input word remains in memory. Moreover, DNCs have been found to perform poorly with low numbers of weight parameters. Therefore, we propose a robust memory deallocation method using a limited retention vector. The limited retention vector determines whether the network increases or decreases its usage of information in external memory according to a threshold. We experimentally evaluate the robustness of a DNC implementing the proposed approach according to the size of the controller and external memory on the enwik8 LM task. When we decreased the number of weight parameters by 32.47%, the proposed DNC showed a low bits-per-character (BPC) degradation of 4.30%, demonstrating the effectiveness of our approach in language modeling tasks.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.936-939
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• 1996

In this paper, two specially designed associative mapping memories, called Associative Mapping Elements(AME) and Multiple-Digit Overlapping AME(MDO-AME), are presented for learning of nonlinear functions including kinematics and dynamics of robot manipulators. The proposed associative mapping memories consist of associative mapping rules(AMR) and weight update rules(WUR) which guarantee generalization and specialization of input-output relationship of learned nonlinear functions. Two simulation results, one for supervised learning and the other for unsupervised learning, are given to demonstrate the effectiveness of the proposed associative mapping memories.

• International Journal of Computer Science & Network Security
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• v.22 no.5
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• pp.327-329
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• 2022

Education is affected by technical and scientific developments. Progress in one of these areas leads give way to new educational methods and strategies. One of these advanced learning modes is what has been conventionally termed as Micro-learning (ML). It has emerged in educational technology as a result of advances in information technology as well as advances in research in memory, brain, and social-cognitive processes.In this paper, the researcher discusses micro-learning in terms of its concepts, tools, and associated concepts, advantages and disadvantages.

• Journal of Ginseng Research
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• v.20 no.1
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• pp.7-14
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• 1996

This study was performed to examine the effect of red ginseng total saponin and extract on memory in mice using one trial step-down type passive avoidance method. Red ginseng total saponins (No. 1: PD/PT ratio=1.24, No. 2: PD/PT ratio=1.47) were prepared with the different mixing ratio by using the parts of red ginseng. In single administration of total saponin No. 1 (100 mg/ kg, bw) or No. 2 (50 mg/kg, bw) increased the latency time as compared with control group but was not statistically significant. Treatment of total saponin No. 1 (50 mg/kg, bw) for 10 days produced an increase of latency time but was not statistically significant. In scopolamine-induced memory deficient mice total saponin No. 1 (50 mg/kg, bw) and No. 2 (100 mg/kg, bw) significantly improved the latency time. These results show that red ginseng total saponin may improve the memory of sco-polamine-induced memory deficient mice and have nootropic activity.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 1999.06a
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• pp.95-96
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• 1999

The authors have considered the 1/f fluctuation of vial rhythm with $1/f\beta$ spectrum of $\alpha$ wave in relation to the invigoration for the learning memory by paid their attention to the hippocampus protocol in this paper. At the first clinical experiment, the data of the remembrance test at short period is able to make as the foundation of the repeat memory. It can replace this memory with long period memory through the hippocampus by the superposition of the same memory-nerve circuits.

• Electronics and Telecommunications Trends
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• v.38 no.5
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• pp.23-33
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• 2023

With the widespread demand from data-intensive tasks such as machine learning and large-scale databases, the amount of data processed in modern computing systems is increasing exponentially. Such data-intensive tasks require large amounts of memory to rapidly process and analyze massive data. However, existing computing system architectures face challenges when building large-scale memory owing to various structural issues such as CPU specifications. Moreover, large-scale memory may cause problems including memory overprovisioning. The Compute Express Link (CXL) allows computing nodes to use large amounts of memory while mitigating related problems. Hence, CXL is attracting great attention in industry and academia. We describe the overarching concepts underlying CXL and explore recent research trends in this technology.

• BMB Reports
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• v.49 no.12
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• pp.671-680
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• 2016

Accumulating evidence indicates many brain functions are mediated by epigenetic regulation of neural genes, and their dysregulations result in neuronal disorders. Experiences such as learning and recall, as well as physical exercise, induce neuronal activation through epigenetic modifications and by changing the noncoding RNA profiles. Animal models, brain samples from patients, and the development of diverse analytical methods have broadened our understanding of epigenetic regulation in the brain. Diverse and specific epigenetic changes are suggested to correlate with neuronal development, learning and memory, aging and age-related neuronal diseases. Although the results show some discrepancies, a careful comparison of the data (including methods, regions and conditions examined) would clarify the problems confronted in understanding epigenetic regulation in the brain.