• Title/Summary/Keyword: Membrane module

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A Study on Affinity Chromatography of Protein by Flat and Hollow-Fiber Membrane Module (평판막 및 실관막 모듈에 의한 단백질의 친화성 크로마토그래피에 관한 연구)

  • 이광진;염경호
    • Membrane Journal
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    • v.8 no.1
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    • pp.50-58
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    • 1998
  • Protein affinity membranes were prepared via coating of chitosan gel on the porous flat and hollow-fiber polysulfone membranes, followed by the immobilization of the reactive dye (Cibacron Blue 3GA) to the chitosan gel. Maximum protein binding capacity of these affinity membranes was about 70 $\mu{g/cm}^2$. Using the affinity flat membrane module, the elution chromatography of human serum albumin (HSA) was performed to determine the optimum condition of eluent buffer. The optimum condition of eluent was the universal buffer solution of 0.06 M concentration containing 1 M KCl at pH 10. For the frontal chromatography of HSA using the flat module, the dynamic protein binding capacity was rapidly decreased from the equilibrium values with increasing flow rate and HSA concentration of the loading solution. However, in the case of hollow-fiber module, the dynamic binding capacity was maintained an equilibrium value without depending on the operating conditions. These results showed that the hollow-fiber module was more effective than the flat module as an affinity chromatography column.

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Modeling of Pervaporation Process: Prediction of Feed Temperature Distribution in A Frame and Plate Type of Membrane Module (판틀형 투과증발 막모듈내에서 feed 온도 분포 예측을 위한 모델링)

  • 원장묵;염충균;임지원;배성렬;하백현
    • Membrane Journal
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    • v.6 no.1
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    • pp.44-52
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    • 1996
  • For the purpose of the optimal design of a frame and plate type of pervaporation module, model equations which can predict the effects of feed flow condition on the temperature distribution of the feed developed in the module were established and the temperature distribution with feed flow condition was investigated through the model si$$\mu$ation. With increasing the Reynolds number of feed flow in the module, the flow velocity gradient in the channel height-direction as well as the volume rate of feed which acts as energy source for the evaporation of perrneants on the permeate-side surface of a membrane increased to such an extent that both mass and heat flux in the channel height direction could increase and the temperature drop of feed due to the evaporation of the permeant could be reduced correspondingly. A decrease in channel height caused the temperature drop of feed because of decreasing feed flow in the module. It was observed that the si$$\mu$ation result on the effect of Re on the temperature distribution of feed in the module has an agreement with experiment.

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Enhancement of Ultrafiltration Performance Using Ultrasound (초음파를 이용한 한외여과의 성능 향상)

  • 염경호;육영재
    • Membrane Journal
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    • v.13 no.4
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    • pp.283-290
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    • 2003
  • To improve membrane performance, the dead-end and Cross-flow ultrafiltration with or without ultrasound irradiation onto the membrane module were carried out using a BSA protein solution. Intermittent or continuous irradiation of ultrasound effectively suppressed the formation of fouling on membrane or removed the fouling layers from membrane. Effect of ultrasound irradiation on the enhancement of ultrafiltration performance was more increased at the operating conditions which form more membrane fouling (at the operating conditions of higher feed concentration and TMP, and lower flow rate). The permeate flukes were enhanced up to 1.9 times in case of the dead-end ultrafiltration and 1.5 times in case of the cross-flow ultrafiltration by ultrasound irradiation onto the membrane module.

A study on reducing scale formation on the RO membrane using carbon dioxide (CO2를 이용한 RO 막의 스케일 생성 저감 연구)

  • Pyo, Minsu;Choi, Younggyun
    • Journal of Korean Society of Water and Wastewater
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    • v.30 no.4
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    • pp.391-399
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    • 2016
  • In this study, carbon dioxide ($CO_2$) was used as an inhibitor of scale production on the surface of RO membrane. In order to compare the effects of $CO_2$ injection on scale production, four RO modules: 1) without $CO_2$ injection and anti-scalant (RO module #1), 2) with only $CO_2$ injection (RO module #2), 3) with only anti-scalant (RO module #3), 4) with both $CO_2$ injection and anti-scalant (RO module #4), were operated for 60 days under constant flux mode. The trans-membrane pressure (TMP) was observed to decrease significantly in RO modules with $CO_2$ injection as compared with the other RO modules. When the feed water pH was controlled at 5.0 by injecting $CO_2$, the maximum TMP in RO modules #2 and #4 was founded to decrease by 42 and 40%, respectively. Moreover, the $Ca^{2+}$ concentration in the concentrate was 20mg/L lower in RO modules without $CO_2$ injection which is attributed to the scale formation on the surface of the RO membranes. The SEM-EDS analysis further showed a serious fouled RO membrane surface in RO modules #1 and #3.