• 대한예방한의학회지
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• 제24권2호
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• pp.83-94
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• 2020

Backgrounds : To reduce the patients' economic burden of herbal decoctions use, in 2012, Korean government decided to implement the pilot project of herbal decoctions coverage in the National Health Insurance. Objectives : This study aimed to analyze the policy decision-making process for the pilot insurance project in 2012. Methods : Official documents, research papers, statistical reports, and news articles, etc. on the coverage of herbal decoctions were searched and collected. We used the Kingdon's Policy Stream Model to analyze how the policy of pilot project of herbal decoctions coverage was decided, and who were the main activists for the decision-making process. Results : Components to be included in the 'Problem stream' were the decline in the profits of Korean Medicine institutions, the contraction of the herbal decoctions use, and the fiscal surplus of National Health Insurance. In the 'Policy stream', there were several model studies for herbal decoctions coverage, and examples of herbal benefits in other social insurances. In the 'Political stream', there were the legislative initiatives by member of the National Assembly and the promotion of insurance coverage by the Association of Korean Medicine(AKOM), etc. Policy window for herbal decoctions coverage was opened by the combination of these three streams with the efforts of policy activists, such as the executives of AKOM, and policy researchers. Conclusions : The policy decision process for health insurance coverage of herbal decoctions was analyzed using Kingdon's model, and the analysis shows that the combination of political streams and entrepreneurs' competencies can be an important driving force in policy decision making.

• Molecules and Cells
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• 제42권12호
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• pp.869-883
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• 2019

Interleukin (IL)-15 is an essential immune-modulator with high potential for use in cancer treatment. Natural IL-15 has a low biological potency because of its short half-life and difficulties in mass-production. IL-15Rα, a member of the IL-15 receptor complex, is famous for its high affinity to IL-15 and its ability to lengthen the half-life of IL-15. We have double-transfected IL-15 and its truncated receptor IL-15Rα into CT26 colon cancer cells to target them for intracellular assembly. The secreted IL-15:IL-15Rα complexes were confirmed in ELISA and Co-IP experiments. IL-15:IL-15Rα secreting clones showed a higher anti-tumor effect than IL-15 secreting clones. Furthermore, we also evaluated the vaccine and therapeutic efficacy of the whole cancer-cell vaccine using mitomycin C (MMC)-treated IL-15:IL-15Rα secreting CT26 clones. Three sets of experiments were evaluated; (1) therapeutics, (2) vaccination, and (3) long-term protection. Wild-type CT26-bearing mice treated with a single dose of MMC-inactivated secreted IL-15:IL-15Rα clones prolonged survival compared to the control group. Survival of MMC-inactivated IL-15:IL-15Rα clone-vaccinated mice (without any further adjuvant) exceeded up to 100%. This protection effect even lasted for at least three months after the immunization. Secreted IL-15:IL-15Rα clones challenging trigger anti-tumor response via CD4⁺ T, CD8⁺ T, and natural killer (NK) cell-dependent cytotoxicity. Our result suggested that cell-based vaccine secreting IL-15:IL-15Rα, may offer the new tools for immunotherapy to treat cancer.

• 가족자원경영과 정책
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• 제9권3호
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• pp.45-68
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• 2005

The political activity of women is relatively low. This is mainly because of the social-cultural attitude that confines women's role to housewives, rather than the structural problems that are related to political activities itself. This study has attempted to enhance the political activities of women by examining and providing the practical informations related to the hardships that are experienced by women who are pursuing a career both as a politician as well as a housewife. The sample of this study consisted of women who are assuming chief executives positions in organizations that are related to political activity, including local representatives of the national assembly. A case study was conducted by interviewing 8 female politicians. The contents of the study mostly consists of the personal situations (related to house lives) of these women. Semi-structured questionnaires were used, and the interview was conducted several times. First, the political careers of these women tended to start passively, rather than voluntarily. Second, the negative attitudes that were initially displayed by the family members and close relatives had changed positively through out the course of time. Close relatives, parents/parents-in-law were likely to become helpers of child care and household labor. The husband was likely to be a supporter of the wife's political career, and the children started to understand the roles of their mother as they grew up. Third, the female politicians perceived that the main impediments of women pursuing political careers were the sexually discriminating culture, rather than their own ability. Fourth, the fact that these women had to spend a lot of time outside the house has worsened the role conflict and difficulties of these women who are required to assume dual-roles. Furthermore, the difficulties that are faced publicly and privately has increased the psychological burdens of these women, since politicians, in general, are people who need to maintain their public image.

• 천문학회보
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• 제45권1호
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• pp.64.2-64.2
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• 2020

We present the properties of galaxies in filaments around the Virgo cluster with respect to their vertical distance from the filament spine. Using the NASA-Sloan Atlas and group catalogs, we select galaxies that do not belong to groups in filaments. The filament member galaxies are then defined as those located within 3.5 scale length from the filament spine. The filaments are mainly (~86%) composed of low-mass dwarf galaxies of logh2M∗/M⊙ < 9 dominantly located on the blue cloud in color-magnitude diagrams. We observe that the g - r color and stellar mass of galaxies correlate with their vertical distance from the filament spine in which the color becomes red and stellar mass decreases with increasing vertical filament distance. The galaxies were divided into two subsamples in different stellar mass ranges, with lower-mass (logh2M∗/M⊙ ≤ 8) galaxies showing a clear negative g-r color gradient, whereas higher-mass (logh2M∗/M⊙ > 8) galaxies have a flat distribution against the vertical filament distance. We observe a negative EW(Hα) gradient for higher-mass galaxies, whereas lower-mass galaxies show no distinct variation in EW(Hα) against the vertical filament distance. In contrast, the NUV - r color distribution of higher-mass galaxies shows no strong dependence on the vertical filament distance, whereas the lower-mass galaxies show a distinct negative NUV - r color gradient. We do not witness clear gradients of HI fraction in either the higher- or lower-mass subsamples. We propose that the negative color and stellar mass gradients of galaxies can be explained by mass assembly from past galaxy mergers at different vertical filament distances. In addition, galaxy interactions might be responsible for the contrasting features of EW(Hα) and NUV - r color distributions between the higher- and lower-mass subsamples. The HI fraction distributions of the two subsamples suggest that ram-pressure stripping and gas accretion could be ignorable processes in the Virgo filaments.

• 인터넷정보학회논문지
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• 제16권4호
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• pp.149-156
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• 2015

개인정보보호위원회는 대통령 소속으로 그 권한에 속하는 업무를 독립적으로 수행하며, 장관급인 위원장과 차관급인 상임위원을 포함하여 총 15명의 위원(대통령 지명 5, 국회 선출 5, 대법원 지명 5)으로 구성된다. 개인정보 보호위원회의 주요 기능은 개인정보 보호 관련 주요 정책 심의 의결 및 법령 제도 개선, 개인정보 보호 관련 공공기관 간 의견 조정, 중앙행정기관, 지방자치단체 및 헌법기관의 침해행위 중지 등 개선권고, 개인정보 보호에 관한 연차보고서의 국회 제출 등이다. 현행 개인정보보호법제는 독립된 형태의 외부감독기관인 개인정보보호위원회와 소관 부처들이 동시에 개인정보보호에 관하여 규율하는 다중규율체계가 특징이다. 현행법에 규정된 개인정보보호위원회의 기능과 역할은 국제적 기준이나 그동안 논의되었던 수준에 비하면 보호기구의 독립성과 권한 등에서 많이 부족하다. 이러한 위원회는 효율적인 개인정보보호를 위한 독립된 기구로서 충분한 역할을 하기 어렵다고 판단된다. 따라서 개인정보보호위원회의 설립취지를 살리는 법개정작업을 제안하고자 한다.

• 분석과 대안
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• 제8권1호
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• pp.137-167
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• 2024

본 연구는 시민교육법안이 무려 13차례나 걸쳐 입법에 실패하게 된 원인을 해명하고자 하였다. 연구 결과 발견한 사실은 첫째, 쟁점 법안에 대한 원내 소수파의 입법 전략 부재이다. 시민교육법안은 이념적 충돌 여지가 큰 쟁점 법안이었는데, 19대 이후 특정 정당의 원내 소수파만으로 추진되었다. 민주당의 발의 의원들은 이 법안이 당론으로 채택될 수 있도록 당내 영향력을 발휘하거나, 총선과 대선의 주요 공약으로 발전시키는 등의 적극적 입법 전략을 구사하지 않았다. 둘째, 불리한 여론 지형 속에서 법안 서명 의원들은 물론이고 시민단체의 일관된 소극적 대응이다. 입법 과정에서는 좌파이념의 확산에 대한 우려, 예산과 조직의 낭비, 교육의 중립성·공정성 침해 등 반대 의견이 압도하였다. 또한, 시민교육의 담당 주체이어야 할 현장 교사와 시민단체의 방관적 자세 또한 입법 실패의 배경으로 작용하였다. 셋째, 이해관계자 사이에서 최근의 이론적 연구 및 세계의 정책 흐름 등에 대한 신뢰할만한 정보의 공유가 부족하여 여야 합의를 통한 입법화에 실패하게 되었다.

• 한국구조물진단유지관리공학회 논문집
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• 제22권1호
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• pp.190-198
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• 2018

리모델링 시장이 커짐에 따라 품질이 우수한 건축물의 내장재 및 외장재들이 개발되고 있다. 개발된 내장재 및 외장재를 건축물의 구조체에 시공하기 위해서 구조체에 하지 철물을 설치하여야 한다. 건축물의 내장재 및 외장재 설치, 데크, 무대 및 마루 등의 시공 시 지지해주는 하부 구조물을 하지철물이라 한다. 하지 철물은 수평재와 수직재를 현장에서 용접 접합을 하여 구조체에 설치하는 방법이 주로 사용되었다. 일반적인 용접접합 방식의 시공은 용접 불씨에 의한 화재 발생으로 인명 및 재산 손실 문제와 전문용접공 부족으로 인한 비전문 용접공 시공에 따른 내구성 저하 문제 등이 발생하고 있다. 하지철물의 시공방법도 안전사고 및 시공의 용이성을 위하여 용접 접합 방법에서 무용접 접합 방법으로 개선되어지고 있다. 이는 화재예방 가설재와 소화장비 및 인원이 불필요하고 볼트조립으로만 시공이 가능하여 인건비 절감과 공기단축이 가능하다. 이에 용접을 사용하지 않는 무용접 하지 트러스 공법을 이용하여 접합부 거동을 실험하여 검증하고자 한다. 또한, 무용접 접합방법으로 시공 시 볼트 체결부분에서 틀어짐 현상이 발생하기도 하여 이를 보완하는 방법으로 각관, 유격방지 브라켓, 파스터, 홈볼트 체결을 통하여 일반 볼트접합인 각관, 화스너, 홈볼트 조립방법에서 좌우간의 틀어짐 현상을 방지하고 부재간의 미끄러짐 현상을 제어할 수 있도록 하는 시스템을 적용하여 접합부의 거동을 평가하고자 한다. 그 결과 무용접 접합방식의 하지철물 골조는 지진하중저항시스템에서 내진등급에 따라 요구되는 허용 층간변위각 0.01~0.02 보다 매우 큰 부재각까지 변형한 것으로 나타나 충분한 변형성능을 확보하고 있음을 알 수 있었다.

• 무역상무연구
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• 제12권
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• pp.65-84
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• 1999

During the past few decades, we have witnessed three approaches to overcome the legal disparities between trading countries: - determining the individual governing law in accordance with the conflict of laws principle; - unifying and harmonizing private international law into uniform rules and substantive laws under the auspices of ICC, UNCITRAL, UNIDROIT and various NGOs ; and - drafting model laws like the UNCITRAL Model Law on Electronic Commerce and promoting member countries to enact them. Against this backdrop, the United Nations Convention on Contracts for the International Sale of Goods (CISG) and the process by which it was adopted, established the benchmark for the unification of commercial law. The CISG, completed in 1980, merged civil and common law concepts and came into force in 1988 after a certain number of countries endorsed the treaty. Besides the CISG, the U.N. Limitations Convention and the UNIDROIT Principles of International Commercial Law, to name a few, have attempted to set cross-border legal norms and standards in the international business transactions. However, since the advent of computer-based commerce, there have emerged all-out efforts to establish uniform rules before national legal systems have been developed. As a consequence, the Model Law on Electronic Commerce has become a specimen legislation covering functional equivalents of paper-based writing and signature. For the credit enhancement exemplified by the Uniform Rules for Demand Guarantees (ICC Publication No.458), the UNCITRAL prepared the U.N. Convention on Independent Guarantees and Stand-by Letters of Credit, which was adopted by the U.N. General Assembly in 1995 but remains still not effective as only two countries have ratified this treaty so far. In this connection, two draft conventions underway at UNIDROIT and UNCITRAL deserve our attention as the probability of unification in the Korean Peninsula is mounting. They are to create security interests for commercial finance in moveable equipment and accounts receivable. The UCC-type security rights are regarded to be useful to enable the North Koreans with limited properties to borrow from the banks.

• 기록학연구
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• 제68호
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• pp.243-279
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• 2021

고(故) 노회찬 의원은 한국 진보정치의 대표적인 정치인이다. 노동운동, 노동자 정치조직화 운동, 진보정당 건설 운동에 매진하였으며, 17, 19, 20대 국회의원으로 의정활동을 수행했다. 그가 남긴 기록은 노동자 정치세력화의 기록이고, 진보정당의 기록이며 고뇌하고 실천하는 정치인의 기록이다. 또 실향민의 아들로써, 유신시기 고민하는 학생운동가로, 그러면서도 첼로를 켰던 문화적 소양의 한 인간의 기록이기도 하다. 이 연구는 노회찬이 남긴 기록의 수집, 관리 현황과 기록을 둘러싼 맥락과 기록의 내용에 대한 기초적인 연구를 통해 노회찬 아카이브 구축의 과제를 생각해보는 연구이다. 아키비스트의 이러한 기초적인 연구는 아카이브를 구조화하고 이용자들에게 다양한 접근점을 제시함으로써 이후보다 다양한 콘텐츠 개발 및 연구에 이용될 수 있도록 함으로써 아카이브 운영의 선순환이 이루어지도록 하는 역할을 할 것이다.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2019년도 추계학술대회
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• pp.73-73
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• 2019

Angelica gigas Nakai (Korean danggui), a member of the Umbelliferae family, is a Korean traditional medicinal plant whose roots have been used for treating gynecological diseases. Transcriptomics is the study of the transcriptome, which is the complete set of RNA transcripts that are produced by the genome, using high-throughput methods, such as microarray analysis. In this study, transcriptome analysis of A.gigas Nakai was carried out. Transcriptome sequencing and assembly was carried out by using Illumina Hiseq 2500, Velvet and Oases. A total of 109,591,555 clean reads of A. gigas Nakai was obtained after trimming adaptors. The obtained reads were assembled with an average length of 1,154 bp, a maximum length of 13,166 bp, a minimum length of 200 pb, and N50 of 1,635 bp. Functional annotation and classification was performed using NCBI NR, InterprotScan, KOG, KEGG and GO. Candidate genes for phenylpropanoid biosynthesis were obtanied from A.gigas transcriptome and the genes and its proteins were confirmed through the NCBI homology BLAST searches, revealing high identity with other othologous genes and proteins from various plants pecies. In RNA sequencing analysis using an Illumina Next-Seq2500 sequencer, we identified a total 94,930 transcripts and annotated 71,281 transcripts, which provide basic information for further research in A.gigas Nakai. Our transcriptome data reveal that several differentially expressed genes related to flower color in A.gigas Nakai. The results of this research provide comprehensive information on the A.gigas Nakai genome and enhance our understanding of the flower color related gene pathways in this plant.