• 제목/요약/키워드: Mediterranean area

검색결과 54건 처리시간 0.023초

Direct Costs of Cervical Cancer Management in Morocco

  • Berraho, Mohamed;Najdi, Adil;Mathoulin-Pelissier, Simone;Salamon, Roger;Nejjari, Chakib
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제13권7호
    • /
    • pp.3159-3163
    • /
    • 2012
  • Background: For cervical cancer the epidemiological profile is poorly known in Morocco and no data is available concerning the direct medical costs. The purpose of this work is to estimate the direct cost of medical management of invasive cervical cancer during the first year after diagnosis in Morocco. Methods: The estimation of direct costs of medical management of invasive cervical cancer during the first year after diagnosis in Morocco is based on the estimation of individual cost in each stage which covers diagnosis, treatment and follow-up during first year. The cost was estimated per patient and whole cycle-set using the costs for each drug and procedure as indicated by the Moroccan National Agency for Health Insurance. Extrapolation of the results to the whole country was used to calculate the total annual cost of cervical cancer treatments in Morocco. Results: Overall approximately 1,978 new cases of cervical cancer occur each year in Morocco. The majority (82.96%) of these cases were diagnosed at a late stage (stageII or more). The cost of one case of cervical cancer depends on stage of diagnosis, the lowest cost is $382 for stageCis followed by the cost of stageIA1 for young women (< 40 years) which is $2,952. The highest cost is for stageIV, which is $7,827. The total cost of cervical cancer care for one year after diagnosis is estimated at $13,589,360. The share allocated to treatment is the most important part of the global care budget with an annual sum of $13,027,609 whereas other cost components are represented as follows: $435,694 for annual follow-up activity and $126,057 for diagnosis and preclinical staging. Conclusion: This study provides health decision-makers with a first estimate of costs and the opportunity to achieve the optimal use of available data to estimate the needs of health facilities in Morocco.

Type Distribution of Lymphomas in Lebanon: Five-Year Single Institution Experience

  • Sader-Ghorra, Claude;Rassy, Marc;Naderi, Samah;Kourie, Hampig Raphael;Kattan, Joseph
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권14호
    • /
    • pp.5825-5828
    • /
    • 2014
  • Background: Lymphomas represent the fifth most frequent cancer in Lebanon. However, little is known concerning epidemiologic characteristics and distribution of lymphoid neoplasms according to the 2008 WHO classification. Materials and Methods: We conducted a retrospective study of lymphoma cases diagnosed from 2008 till 2012 at $H\hat{o}tel$-Dieu de France University Hospital. Results: A total of 502 new cases of lymphoma were diagnosed at our institution during a five year period: 119 cases (24%) were Hodgkin lymphomas (HL) and 383 cases (76%) were non-Hodgkin lymphomas (NHL). HLs were equally distributed in both sexes with a mean age at diagnosis of 30 years. Among NHL, 87% (332 cases) were B cell lymphomas, 9% (34 cases) were T cell lymphomas and 4%(17 cases) were classified as precursor lymphoid neoplasms. Among B cell lymphomas, 44% (147 cases) were diffuse large B cell lymphomas (DLBCL), 20% (65 cases) follicular lymphomas and 8% (27 cases) mantle cell lymphomas. DLBCL were equally distributed in both sexes with a mean age of 58 years. Follicular lymphomas were characterized by a male predominance (57%) and a mean age of 60 years. Mantle cell lymphomas showed a pronounced male predominance (85%) with a mean age of 60 years in men and 70 years in women. Some 72% of patients having T cell lymphomas were men, with a mean age of 57 years in men and 45 years in women, while 65% of patients having precursor lymphoid neoplasms were women with a mean age of 22 years in women and 30 years in men. Conclusions: The lymphoma subtype distribution in Lebanon is unique when compared to other countries from around the world. In fact, Hodgkin and follicular lymphomas are more frequent than in most Far Eastern, European and American countries, while T-cell lymphomas and DLBCL are less frequent.

해외지역연구를 위한 전자문화지도의 설계 및 구현 (Design and Implementation of Electronic Culture Atlas for Oversea Region Research)

  • 강지훈;문상호;유영중
    • 한국정보통신학회논문지
    • /
    • 제17권5호
    • /
    • pp.1174-1180
    • /
    • 2013
  • 최근에 미래의 디지털 융합을 위한 많은 관심과 요구가 있다. 특히, 정보기술 분야에서 정보기술은 실생활과 밀접한 관련이 있으므로 지역학, 문학, 인문학 등과 같은 다른 학문들과의 융합이 필요하다. 문화지도는 문화와 관련된 다양한 양상들을 점, 선, 기호 등으로 표현하여 지도에 나타낸 것이다. 즉 지도는 디지털 환경에서 문화를 효율적으로 연구할 수 있는 유용한 도구가 된다. 본 논문에서는 지중해지역 연구와 같은 해외지역 연구를 위하여 전자문화지도를 적용할 수 있는 방안을 제시하고 세부적으로 지중해지역 연구를 위한 전자문화지도를 설계 및 구현한다. 본 연구를 통하여 생성된 전자문화지도를 활용하면 해외지역 연구 결과를 시각적으로 표현할 수 있다. 그리고 이를 통하여 연구 결과를 보다 이해하기 쉽게 되고 새로운 연구에 대한 기초 자료로서의 활용이 가능하다. 또한 인문, 지역학과 IT의 융합학으로서, 해외지역을 연구하는 도구 및 연구결과물의 전시 도구로 활용할 수 있다.

An Epidemiological Study of Cutaneous Leishmaniasis in Al-Jabal Al-Gharbi, Libya

  • Abdellatif, Manal Z.M.;El-Mabrouk, Khamis;Ewis, Ashraf A.
    • Parasites, Hosts and Diseases
    • /
    • 제51권1호
    • /
    • pp.75-84
    • /
    • 2013
  • Cutaneous leishmaniasis (CL) is an endemic parasitic infection in the Mediterranean region, including Libya and its Al-jabal Al-gharbi province. We aimed at studying the occupational relevance as well as other epidemiological aspects of CL. We investigated 140 CL cases who attended at Gharyan outpatient polyclinic during a period of 6 months in 2009. CL infection was clinically diagnosed and confirmed by demonstration of Leishmania parasites on smears from lesions. Our findings showed that males were more affected than females (P=0.04), and people above 10-years were more affected than younger ones (P=0.0001). A significant percent of CL cases belonged to Al-Kawasem subprovince (P=0.0001). Farm-related activities were the most frequent occupations among CL cases (P=0.04). In addition to farm workers, housewives and students are at risk groups since they are engaged at farm activities. Moreover, those who have occupations that require staying outdoors for a part of night, e.g., policemen, are also at risk. Compared to children, adult CL patients had multiple lesions (P=0.001) that were more prevalent in their upper and lower extremities than the face (P=0.0001). We conclude that CL is a major health problem in Al-jabal Al-gharbi province of Libya. The presence of rodents and sandflies makes it a suitable environment for Leishmania to spread in an endemic epidemiological pattern. Being engaged in farming activities or outdoor occupations increases the risk of infection. Various clinical patterns of CL suggest the presence of more than 1 species of Leishmania at Al-jabal Al-gharbi province. We propose that the 2 species responsible for CL in this area are L. major and L. tropica. Further investigations to identify the leishmanial species responsible for CL at Al-jabal Al-gharbi together with adoption of preventive and control programs are needed.

디지털 인문학 시스템의 효율적 개발을 위한 방법에 관한 연구 (A Study on the Method for Efficient Development of Digital Humanities System)

  • 강지훈;이동열;문상호
    • 예술인문사회 융합 멀티미디어 논문지
    • /
    • 제6권7호
    • /
    • pp.389-397
    • /
    • 2016
  • 디지털 인문학 시스템은 정보기술을 활용하여 인문정보나 지식을 사용자에게 효율적으로 공유 및 확산하는 방안이다. 또한 인문학을 연구하는 연구자들에게는 새로운 연구방법론으로 주목받고 있다. 디지털 인문학 시스템은 기존의 정보시스템과는 차별화된 성격을 가진다. 따라서 시스템 구축 시 기존의 정보시스템 구축 방법론이 아닌 디지털 인문학 시스템에 특화된 개발 절차와 관련 인력을 구성할 필요가 있다. 최근 연구되는 디지털 인문학 시스템은 절차나 방법론 없이 기존의 정보시스템 구축방법론을 통해 구축되는 경우가 대부분이며 이로 인해 시스템 구축 후 사용성이나 효율성이 떨어져 시스템 운영에 실패하는 사례가 발생한다. 이에 따라 본 연구에서는 정보기술의 관점에서 다양한 전문분야와의 협업을 통해 효과적이고 창조적인 '디지털 인문학 시스템' 개발 방법에 대해 연구한다. 세부적으로 소프트웨어 공학 관점에서의 정보시스템 구축방법론을 기반으로 디지털 인문학 시스템에 특화된 구축 방법을 제시하고자 한다.

Morphological Characteristics and Distribution of Korean Daphne L.

  • Beom Kyun Park;Balkrishna Ghimire;Eun-Mi Sun;Dong Chan Son;Seung Hwan Oh
    • 한국자원식물학회:학술대회논문집
    • /
    • 한국자원식물학회 2020년도 춘계학술대회
    • /
    • pp.27-27
    • /
    • 2020
  • Daphne L. (Thymelaceae) comprises about 95 species distributing worldwide from N Africa, N India, SE Asia to E Asia and the coast of the Mediterranean of Europe. In Korea, five species of this genus have been described. In this study, we included four species (D. genkwa, D. pseudomezereum, D. kiusiana, D. jejudoensis) from Korea, excluding cultivated D. odora. The morphological characters through local surveys and the re-classification of the specimens collected in the Korea National Herbarium (KH) were carried out and distribution maps for each taxon were also prepared. The major characters include habit, trichomes in winter bud, leaf, and twig, phyllotaxis, inflorescence, size of calyx lobe and trichomes in the calyx tube, etc. The distribution map showed that D. genkwa is mainly distributed in the coastal area of Hwanghaenam-do, Pyeongannam-do, Jeollabuk-do and Jeollanam-do, whereas D. pseudomezereum is distributed in the limestone zone of Gangwon-do, Jeollabuk-do, and Gyeongsangbuk-do. Similarly, D. kiusiana is mostly found in Jeollanam-do, Gyeongsangnam-do, and Jeju-do. In addition, D. jejudoensis is known to be distributed in forests of Murueng, Andeok, and Seonheul-ri in Jeju-do, but recently, new habitat is discovered in the island forest areas of Jeollanam-do. However, some of these individuals showed the characteristics of D. kiusiana, thus before come to any conclusion detailed taxonomic review of D. jejudoensis and D. kiusiana is required.

  • PDF

The use of SMA wire dampers to enhance the seismic performance of two historical Islamic minarets

  • El-Attar, Adel;Saleh, Ahmed;El-Habbal, Islam;Zaghw, Abdel Hamid;Osman, Ashraf
    • Smart Structures and Systems
    • /
    • 제4권2호
    • /
    • pp.221-232
    • /
    • 2008
  • This paper represents the final results of a research program sponsored by the European Commission through project WIND-CHIME ($\underline{W}$ide Range Non-$\underline{IN}$trusive $\underline{D}$evices toward $\underline{C}$onservation of $\underline{HI}$storical Monuments in the $\underline{ME}$diterranean Area), in which the possibility of using advanced seismic protection technologies to preserve historical monuments in the Mediterranean area is investigated. In the current research, the dynamic characteristics of two outstanding Mamluk-Style minarets, which similar minarets were reported to experience extensive damage during Dahshur 1992 earthquake, are investigated. The first minaret is the Qusun minaret (1337 A.D, 736 Hijri Date (H.D)) located in El-Suyuti cemetery on the southern side of the Salah El-Din citadel. The minaret is currently separated from the surrounding building and is directly resting on the ground (no vaults underneath). The total height of the minaret is 40.28 meters with a base rectangular shaft of about 5.42 ${\times}$ 5.20 m. The second minaret is the southern minaret of Al-Sultaniya (1340 A.D, 739 H.D). It is located about 30.0 meters from Qusun minaret, and it is now standing alone but it seems that it used to be attached to a huge unidentified structure. The style of the minaret and its size attribute it to the first half of the fourteenth century. The minaret total height is 36.69 meters and has a 4.48 ${\times}$ 4.48 m rectangular base. Field investigations were conducted to obtain: (a) geometrical description of the minarets, (b) material properties of the minarets' stones, and (c) soil conditions at the minarets' location. Ambient vibration tests were performed to determine the modal parameters of the minarets such as natural frequencies and mode shapes. A $1/16^{th}$ scale model of Qusun minaret was constructed at Cairo University Concrete Research Laboratory and tested under free vibration with and without SMA wire dampers. The contribution of SMA wire dampers to the structural damping coefficient was evaluated under different vertical loads and vibration amplitudes. Experimental results were used along with the field investigation data to develop a realistic 3-D finite element model that can be used for seismic risk evaluation of the minarets. Examining the updated finite element models under different seismic excitations indicated the vulnerability of such structures to earthquakes with medium to high a/v ratio. The use of SMA wire dampers was found feasible for reducing the seismic risk for this type of structures.

Ecosysteme de I′Etang de Berre (Mediterranee nord-occidentale) : Caracteres Generales Physiques, Chimiques et Biologiques

  • Kim, Ki-Tai
    • 환경생물
    • /
    • 제22권2호
    • /
    • pp.247-258
    • /
    • 2004
  • Climatological, hydrological and planktonical research studies, measurements of primary production and photosynthetic efficiency from December 1976 to December 1978 have been carried out in two brackish lakes: Lake Etang de Berre and Lake Etang de Vaine located in the French Mediterranean coast, in the region of Carry-le-Rouet located on the north-west Mediterranean near Marseilles, and in fresh water inflows from 4 Rivers (Touloubre, Durance, Arc, Durancole) to Lake Etang de Berre. Physico-chemical parameters were measured for this study: water temperature, salinity, density, pH, alcalinity, dissolved oxygen (% saturation), phosphate, nitrate, nitrite, silicate etc. Diverse biological parameters were also studied: photosynthetic pigments, phaeopigments, specific composition and biomass of phytoplankton, primary pelagic production etc. Climatical factors were studied: air-temperature, solar-radiation, evaporation, direction (including strength) of winds, precipitation and freshwater volume of the four rivers. The changes in Lake ‘Etang de Berre’ ecosystem depend on the quality of the water in the Durance River, and on the effects of seawater near the entrance of the Caronte Canal. The water quality of the lake varies horizontally and vertically as a result of atmospheric phenomena, maritime currents and tides. The distribution of water temperatures is generally heterogeneous. Southeasterly winds and the Northeasterly Mistral wind are important in the origins of circulated and mixed water masses. These winds are both frequent and strong. They have, as a result, a great effect on the water environment of Lake Etang de Berre. In theory, the annual precipitation in this region is well over eight times the water mass of the lake. The water of the Durance River flows into Lake Etang de Berre through the EDF Canal, amounting to 90% of the precipitation. However, reduction of rainfall in dry seasons has a serious effect on the hydrological characteristics of the lake. The temperature in the winter is partially caused by the low temperature of fresh water, particularly that of the Durance River. The hydrological season of fresh and brackish water is about one month ahead of the hydrological season of sea water in its vicinity. The salinity of Lake Etang de Berre runs approximately 3$\textperthousand$, except at lower levels and near the entrance to the Caronte Canal. However, when the volume of the Durance River water is reduced in the summer and fall, the salinity rises to 15$\textperthousand$. In the lake, the ratio of fresh water to sea water is six to one (6:1). The large quantities of seston conveyed by rivers, particularly the Durance diversion, strongly reduce the transparency in the brackish waters. Although the amount of sunshine is also notable, transparency is slight because of the large amount of seston, carried chiefly by Tripton in the fresh water of the Durance River. Therefore, photosynthesis generally occurs only in the surface layer. The transparency progressively increases from freshwater to open seawater, as mineral particles sink to the bottom (about 1.7kg $m^{-2}a^{-1}$ on the average in brackish lakes). The concentration of dissolved oxygen and the rate of oxygen saturation in seawater (Carry-le-Rouet) ranged from 5.0 to 6.0 $m\ell$ㆍ.$1^{-1}$, and from 95 to 105%, respectively. The amount of dissolved oxygen in Etang de Berre oscillated between 2.9 and 268.3%. The monographs of phosphate, nitrate, nitrite and silicate were published as a part of a study on the ecology of phytoplankton in these environments. Horizontal and vertical distributions of these nutriments were studied in detail. The recent diversion of the Durance River into Lake Etang de Berre has effected a fundamental change in this formerly marine environment, which has had a great impact in its plankton populations. A total of 182 taxa were identified, including 111 Bacillariophyceae, 44 Chlorophyceae, and 15 Cyanophyceae. The most abundant species are small freshwater algae, mainly Chlorophyceae. The average density is about $10^{8}$ cells $1^{-1}$ in Lake Etang de Berre, and about double that amount in Lake Etang de Vaine. Differences in phytoplankton abundance and composition at the various stations or at various depths are slight. Cell biovolume V (equivalent to true biomass), plasma volume VP (‘useful’ biomass) and, simultaneously. the cell surface area S and S/V ratio through the measurement of cell dimensions were computed as the parameters of phytoplankton productivity and metabolism. Pigment concentrations are generally very high on account of phytoplankton blooms by Cyanophyceae, Chlorophyceae and Cryptophyceae. On the other hand, in freshwaters and marine waters, pigment concentrations are comparatively low and stable, showing slight annual variation. The variations of ATP concentration were closely related to those of chlorophyll a and phytoplankton blooms only in marine waters. The carbon uptake rates ranged between 38 and 1091 mg$Cm^{-2}d^{-1}$, with an average surface value of 256 mg; water-column carbon-uptake rates ranged between 240 and 2310 mg$Cm^{-2}d^{-1}$, with an average of 810, representing 290 mg$Cm^{-2}$, per year 45 000 tons per year of photosynthetized carbon for the whole lake. Gross photosynthetic production measured by the method of Ryther was studied over a 2-year period. The values obtained from marine water(Carry-le-Rouet) ranged from 23 to 2 337 mg$Cm^{-2}d^{-1}$, with a weighted average of 319, representing about 110 gCm$^{-2}$ per year. The values in brakish water (Etang de Berre) ranged from 14 to 1778 mg$Cm^{-2}d^{-1}$, with a weighted average of 682, representing 250 mg$Cm^{-2}$ per year and 38 400 tons per year of photosynthesized carbon for the whole lake.

Combined Effect of CO2 andTemperature on Wheat Powdery Mildew Development

  • Matic, Slavica;Cucu, Maria Alexandra;Garibaldi, Angelo;Gullino, Maria Lodovica
    • The Plant Pathology Journal
    • /
    • 제34권4호
    • /
    • pp.316-326
    • /
    • 2018
  • The effect of simulated climate changes by applying different temperatures and $CO_2$ levels was investigated in the Blumeria graminis f. sp. tritici/wheat pathosystem. Healthy and inoculated plants were exposed in single phytotrons to six $CO_2$+temperature combinations: (1) 450 ppm $CO_2/18-22^{\circ}C$ (ambient $CO_2$ and low temperature), (2) 850 ppm $CO_2/18-22^{\circ}C$ (elevated $CO_2$ and low temperature), (3) 450 ppm $CO_2/22-26^{\circ}C$ (ambient $CO_2$ and medium temperature), (4) 850 ppm $CO_2/22-26^{\circ}C$ (elevated $CO_2$ and medium temperature), (5) 450 ppm $CO_2/26-30^{\circ}C$ (ambient $CO_2$ and high temperature), and (6) 850 ppm $CO_2/26-30^{\circ}C$ (elevated $CO_2$ and high temperature). Powdery mildew disease index, fungal DNA quantity, plant death incidence, plant expression of pathogenesis-related (PR) genes, plant growth parameters, carbohydrate and chlorophyll content were evaluated. Both $CO_2$ and temperature, and their interaction significantly influenced powdery mildew development. The most advantageous conditions for the progress of powdery mildew on wheat were low temperature and ambient $CO_2$. High temperatures inhibited pathogen growth independent of $CO_2$ conditions, and no typical powdery mildew symptoms were observed. Elevated $CO_2$ did not stimulate powdery mildew development, but was detrimental for plant vitality. Similar abundance of three PR transcripts was found, and the level of their expression was different between six phytotron conditions. Real time PCR quantification of Bgt was in line with the disease index results, but this technique succeeded to detect the pathogen also in asymptomatic plants. Overall, future global warming scenarios may limit the development of powdery mildew on wheat in Mediterranean area, unless the pathogen will adapt to higher temperatures.

유럽 단일항공시장 형성에 관한 지역주의적 접근 - EU의 미국에 대한 전략적 대응 관점에서 - (An Approach to Regionalism on the Creation of a European Single Aviation Market: From the Viewpoint of the EU's Strategic Response against the US)

  • 서정욱
    • 대한지리학회지
    • /
    • 제39권6호
    • /
    • pp.955-970
    • /
    • 2004
  • 세계항공시장은 최근 세계화의 흐름속에서 자유화. 규제완화, 민영화 추세에 있으며. 항공자유화를 지역적 단위에서 실현하는 지역블록화 현상이 뚜렷해지고 있다. 본 연구는 세계항공시장의 지역블록화 현상과 그 배후에 작용하고 있는 정치경제학적인 메카니즘을 유럽 단일항공시장 형성을 중심으로 고찰한다. 연구결과 유럽 단일항공시장 형성은 미국이라는 거대한 항공시장의 역내 자유화와 이를 바탕으로 한 미국중심의 범세계적 항공자유화 네트워크 구축에 대응하여 유럽 항공산업의 대미경쟁력 제고를 위한 전략적 고려의 산물이라는 것을 보여 준다. 보다 구체적으로 유럽 단일항공시장은 미국의 유럽 항공산업에 대한 분리지배 및 포위전략에 맞서 유럽항공사들이 세계최대의 항공노선인 북대서양 노선에서 미국항공사들과 보다 효율적으로 경쟁할 수 있도록 하기 위한 유럽연합 차원의 전략적 대응이라는 현상을 보여준다. 최근 유럽 단일항공시장은 주변의 지중해연안국가 및 발칸국가들까지 편입시킴으로써 범유럽항공협력의 지속적인 추진과 유럽공동항공지역의 확대 및 심화를 통해 향후 역외국가와의 교섭에 있어 협상 레버리지를 더욱 높여 나가려는 추세에 있다. 이러한 연구결과는 우리나라를 포함한 동북아 지역도 항공부문의 지역주의를 창설하는 것이 역내 항공산업의 발전 및 역외교섭력 제고면에서 시급하다는 것을 시사한다.