• Title/Summary/Keyword: Medicine plants

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Evaluation of the Antimicrobial Activity of Seven Gabonese Medicinal Plants against Methicillin-Resistant Staphylococcus aureus and Salmonella

  • Obiang-Obounou, Brice W.;Kang, Ok-Hwa;Choi, Jang-Gi;Keum, Joon-Ho;Kim, Sung-Bae;Kim, Yong-Sik;Mun, Su-Hyun;Choi, Mi-Sun;Maroufath, Lamidi;Kwon, Dong-Yeul
    • Natural Product Sciences
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    • 제17권1호
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    • pp.33-37
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    • 2011
  • The plant species reported here are used by traditional healers in Gabon for different ailments such as wounds, malaria, fever, gonorrhea or diarrhea. The aim of this study was to evaluate the antimicrobial activities of 7 plants (Strombosiopsis tetrandra, Tetraberlinia bifoliolata, Dichapetalum barbatum, Guibourtia demeusii, Dacryodes normandii, Manniophytum fulvum, Paropsia grewoides) against different strains of both Methicillin-Resistant Staphylococcus aureus (MRSA) and Salmonella. Disc diffusion was first used to determine the antimicrobial effectiveness of the plants' ethanolic extracts. Then the minimum inhibitory concentrations of the crude extracts of either leaves or stem barks of the 7 plants were determined using broth micro-dilution. The ethanolic plant extracts showed very good activity against both MRSA and Salmonella strains where the MICs ranged from $250\;{\mu}g/ml$ to $1000\;{\mu}g/ml$. The study shows that many of the tested plants used by Gabonese traditional healers have antimicrobial activities and give support to their traditional use.

한국산(韓國産) 서이목(鼠李目) 식물에 관한 본초학적(本草學的) 연구(硏究) (A Herbological study on the plants of Rhamnaceae in Korea.)

  • 문대원;정종길
    • 대한본초학회지
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    • 제21권3호
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    • pp.21-33
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    • 2006
  • Objectives : The plans can be used for medicinal purposes among Rhamnales in korea and examined their effects and distributions. Methods : The examined herbalogical books and research papers which published at home and abroad. Results : 1. There are up to 10 genera and 35 species in the Rhamnales in Korea, and among them medicinal plants are 9 genera, 17 species, some 45% in total. 2. Rhamnella genus is the main kind that has 9 species among 35 species in the Rhamnales, of which medicinal plants are 4 species. 3. The cortex in the Rhamnales is the main part which is used medicinally. And the number of the species in the Rhamnales which are used medicinally is 16. 4. According to the nature and flavor of medicinal plants in the Rhamnales, they were classified into balance 33 species, and warm 13; sweet taste 28 and bitter taste 24 in the order. 5. According to meridian propism of medicinal plants in the Rhamnales, they were classified into heart meridian 8 species, stomach meridian 7, and liver meridian 6 in the order. 6. According to the properties and principal curative action, they were classified into drugs for detoxicant 30 species. drugs for antifebrile 23, and drugs for drain damp 13 in the order. 7. The number of toxic species in the Rhamnales was examined to be 6 species. Conclusion : There were totaled to 10 genera and 35 species in Rhamnales in Korea and among them medicinal plants are 9 genera, 17species, some 45% in total.

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Classification of Plants into Families based on Leaf Texture

  • TREY, Zacrada Francoise;GOORE, Bi Tra;BAGUI, K. Olivier;TIEBRE, Marie Solange
    • International Journal of Computer Science & Network Security
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    • 제21권2호
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    • pp.205-211
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    • 2021
  • Plants are important for humanity. They intervene in several areas of human life: medicine, nutrition, cosmetics, decoration, etc. The large number of varieties of these plants requires an efficient solution to identify them for proper use. The ease of recognition of these plants undoubtedly depends on the classification of these species into family; however, finding the relevant characteristics to achieve better automatic classification is still a huge challenge for researchers in the field. In this paper, we have developed a new automatic plant classification technique based on artificial neural networks. Our model uses leaf texture characteristics as parameters for plant family identification. The results of our model gave a perfect classification of three plant families of the Ivorian flora, with a determination coefficient (R2) of 0.99; an error rate (RMSE) of 1.348e-14, a sensitivity of 84.85%, a specificity of 100%, a precision of 100% and an accuracy (Accuracy) of 100%. The same technique was applied on Flavia: the international basis of plants and showed a perfect identification regression (R2) of 0.98, an error rate (RMSE) of 1.136e-14, a sensitivity of 84.85%, a specificity of 100%, a precision of 100% and a trueness (Accuracy) of 100%. These results show that our technique is efficient and can guide the botanist to establish a model for many plants to avoid identification problems.

한약재 물 추출물의 생리활성 검색 및 MPTP-유도 신경독성에 대한 대황의 보호효과 (Screening of the Biologoical Activity from Water Extracts of the Medicinal Plants and the Protective Effect of R. palmatum on MTPT-induced Neurotoxicity)

  • 김태은;윤여민;박용인;김윤석;전병훈;김명동
    • 동의생리병리학회지
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    • 제18권6호
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    • pp.1666-1685
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    • 2004
  • This present study was designed to screen medicinal plants for the treatment of brain diseases such as Parkinson's disease or aging. We tested the effects of the water extracts from 38 species medicinal plants on antioxidant capacity, monoamine oxidase B (MAO-B) inhibitory activity, acetylcholinesterase (AChE) inhibition and antiperoxidation activity in vitro. The water extracts from 38 species were tested on their antioxidant activity using radical scavenging effects against ABTS+. The water extract of C. sappan was showed the highest antioxidant capacity, the antioxidant activity at 1 Jig of herbal extract being 0.38mM TE. Lipid peroxidation in brain homogenates induced by NADPH and ADP-Fe/sup 2+/ was strong inhibited by C. sappan and R. palmatum extracts. Among the 38 medicinal plants investigated, R. palmatum showed significant biological activity (antioxidant capacity, MAO-B inhibiory activity, and AChE inhibitory activity). The protective efficacy of R. palmatum water extract on 1-methyl-4­phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism and its possible mechanism were studied in C57BL/6 mice. Treatment of R. palmatum water extract protected biomacromolecules such as lipids from oxidative damage induced by MPTP. The content of MDA in brain tissue was decreased significantly by R. palmatum extract. These results suggest that R. palmatum water extract plays on effective role in attenuating MPTP-induced neurotoxicity in mice. This protective effect of R. palmatum might be estimated the result from the inhibitory activity on monoamine oxidase B and the enhancement of antioxidant activity.

온라인 생물정보 플랫폼에 기반한 가산의 관속식물목록 (A checklist of Gasan Mt.: an online platform for virtual specimens)

  • 양선규;남보미;장주은;최미정;최고야;정경숙;최혁재
    • 식물분류학회지
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    • 제50권4호
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    • pp.453-474
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    • 2020
  • 경상북도 칠곡군에 위치한 가산(902 m)의 관속식물상을 밝히고 주요 식물들의 분포를 파악하기 위하여 2014년부터 2015년까지 10회의 현지조사를 수행하였다. 현지조사 결과 가산의 관속식물 81과 212속 289종 8아종 20변종 5품종으로 총 322분류군의 분포를 확인하였다. 조사된 분류군 중 한반도 특산식물은 14분류군, 희귀식물은 6분류군이 확인되었고 식물구계학적 특정식물종은 48분류군이었으며 귀화식물은 14분류군으로 나타났다. 조사지역은 세잎승마와 노랑무늬붓꽃의 분포한계 지역이었으며 가산산성 일대에서 금붓꽃과 노랑무늬붓꽃의 잡종개체군을 확인하였다. 조사지역에서 수집된 관속식물 증거표본 325점은 한국한의학연구원 한약표준표본관에 보관하였고 디지털 이미지로 만들어 https://oasis.kiom.re.kr/herblib/ 에 공유하였다. 본 연구는 국내 식물상 연구분야에서 증거표본의 디지털 이미지를 공유한 최초의 연구로서 큰 의미를 갖는다.

중국산 약용식물의 최종당화산물 생성저해활성 검색 (V) (Screening of Herbal Medicines from China with Inhibitory Activity on Advanced Glycation End Products (AGEs) Formation (V))

  • 김영숙;최성훈;김주환;김진숙
    • 생약학회지
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    • 제42권1호
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    • pp.46-53
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    • 2011
  • Advanced glycation end products (AGEs) have been postulated to play a central role in the development of diabetic complications. A variety of different agents that inhibit AGEs have been under investigation. In this study, 66 herbal medicines from China have been investigated with an in vitro evaluation system using AGEs formation inhibitory activity. Of these, 31 herbal medicines ($IC_{50}$ < $50\;{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Particularly, 5 herbal medicines, Camptotheca acuminata (branches and leaves), Quercus franchetii (branches), Camellia pitardii (leaves, branches, and fruits), Antidesma bunius (whole plants), and Loranthus parasiticus (whole plants) showed more potent inhibitory activity (approximately 6-20 fold) than the positive control aminoguanidine ($IC_{50}=52.96\;{\mu}g/ml$).

Ethnomedicinal and pharmacological activities of Mochrus (Bombax ceiba Linn.): An overview

  • Rani, Seema;Rahman, Khaleequr;Sultana, Arshiya
    • 셀메드
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    • 제6권1호
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    • pp.2.1-2.9
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    • 2016
  • Traditional system of medicine mentioned the use of plants in treatment of various human ailments. Mochrus (Bombax ceiba Linn.) is one of the medicinal plants used in Unani medicine since time immemorial. It is a very tall tree with approximately 150 feet height. It is widely found in temperate Asia, tropical Asia, Africa and Australia. In India, it can be found at altitudes up to 1500 m. In peninsular India, the tree is very common in the dry as well as moist deciduous forests and near rivers. It is reported to possess qabiz (constipative); mujaffif (siccative); muqawwi rehm (uterine tonic); nafi sailan rehm (beneficial in leucorrhea); mumsik wa mughalliz mani (increase consistency of semen); muallide mani (production of semen); habise tams (amenorrhoic); dafi fasaad khoon wa safra (purifies blood and bile); taskeen hiddat aza (hotness of organs); muqawi asnan wa lissa (tonic to teeth and gums) etc. Ethnobotanical studies prove that it is used in diarrhoea, asthma, impotency, boils, wounds, leprosy, pimples and many other skin diseases. It is an anthelmintic remedy since ancient time. Pharmacological studies like hypotensive, antioxidant, analgesic, anti-inflammatory, antipyretic, antiangiogenic, anti- bacterial, cytotoxic, hepatoprotective, diuretic, anthelmintic, anticancer, spermatogenic and anti-helicobacter pylori activities have been evaluated for various parts of this plant that confirms to its use in classical medicine.

Plant-derived PAP proteins fused to immunoglobulin A and M Fc domains induce anti-prostate cancer immune response in mice

  • Yang Joo Kang;Deuk-Su Kim;Seyoung Kim;Young-Jin Seo;Kisung Ko
    • BMB Reports
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    • 제56권7호
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    • pp.392-397
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    • 2023
  • In this study, recombinant Fc-fused Prostate acid phosphatase (PAP) proteins were produced in transgenic plants. PAP was fused to immunoglobulin (Ig) A and M Fc domain (PAP-IgA Fc and PAP-IgM Fc), which were tagged to the ER retention sequence KDEL to generate PAP-IgA FcK and PAP-IgM FcK. Agrobacterium-mediated transformation was performed to produce transgenic tobacco plants expressing four recombinant proteins. Genomic PCR and RT-PCR analyses confirmed the transgene insertion and mRNA transcription of PAP-IgA Fc, PAP-IgM Fc, PAP-IgA FcK, and PAP-IgM FcK in tobacco plant leaves. Western blot confirmed the expression of PAP-IgA Fc, PAP-IgM Fc, PAP-IgA FcK, and PAP-IgM FcK proteins. SEC-HPLC and Bio-TEM analyses were performed to confirm the size and shape of the plant-derived recombinant PAP-Fc fusion proteins. In mice experiments, the plant-derived IgA and IgM Fc fused proteins induced production of total IgGs including IgG1 against PAP. This result suggests that IgA and IgM Fc fusion can be applied to produce recombinant PAP proteins as a prostate cancer vaccine in plant expression system.

First Report of Soft Rot Induced by Dickeya dadantii on Euphorbia hypogaea in Korea

  • Ismaila Yakubu;Ji Ho Song;Yun Ju Lee;Min A Son;Su Hyeon Han;Hyun Gi Kong
    • 식물병연구
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    • 제30권1호
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    • pp.95-98
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    • 2024
  • In a survey conducted in March 2023, Euphorbia hypogaea plants cultivated within greenhouses in Yongin, Korea exhibited water-soaked areas near the stem base, close to the soil. Subsequent isolation from diseased E. hypogaea led to the identification of a bacterial strain, designated as CBNUMPBL-103. The isolate was identified as Dickeya dadantii through sequencing of the 16s rRNA and phylogenetic analysis. The pathogenicity of the isolate was confirmed by inoculating it into healthy E. hypogaea, resulting in the manifestation of similar symptoms observed during the survey. The re-isolated strain recovered from inoculated plants showed a similar morphology with the inoculated strain. This is the first documentation of D. dadantii causing soft rot of E. hypogaea in Korea.