• 대한한방부인과학회지
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• 제33권1호
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• pp.36-58
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• 2020

Objectives: We conducted a literature study on the treatment trends in China to find out the possibility of Oriental medicine treatment of atypical hyperplasia of breast (AHB). Methods: RCTs (randomized controlled trial) on AHB were collected from CNKI (China National Knowledge Infrastructure). The search words were "乳腺增生", "乳腺囊性增生", "乳癖", "中医", "中药" and "中西医结合". The search period was limited from July 2006 to May 2017. Finally, we selected 107 RCTs which were clinical studies to find out the effectiveness of Chinese herbal medicine in comparison with Western medicine. After reviewing, we investigated Chinese herbal medication guide, Chinese treatment method and prescriptions. And the correlation between the treatments and the medicinal herbs was investigated to be useful in the clinical practice. Results: 1. The administration of herbal medicine was 58.9 percent in 63 cases, followed by menstrual cycles, and 41.1 percent in 44 cases, regardless of menstrual cycles. 2. In the basic frequency analysis between the treatment and the medicinal herb, the frequency of dissipate binds (散結) was the highest. Next, there was a high frequency of therapies such as activating blood-activating (活血), relieve pain (止痛), soothe the liver (疏肝), regulate qi (理氣), resolve phlegm (化痰), soften hardness (軟堅), resolve depression (解鬱), move qi (行氣) of frequency was high. In herbal medicine, bupleuri radix (柴胡), cyperi rhizoma (香附子), angelicae gigantis radix (當歸), fritillaria thunbergii bulb (貝母), paeoniae radix alba (白芍藥), prunellae spica (夏枯草), corydalis rhizoma (玄胡索) showed high frequency. 3. We finded out the correlation between the frequent treatment methods and the medicinal herbs using Text Mining. Conclusions: These findings are thought to help implement Korean traditional medicine treatments for AHB.

• 한국균학회지
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• 제41권2호
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• pp.127-131
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• 2013

본 연구는 한려해상국립공원 인근의 경남지역의 야생버섯에 대한 전통지식을 조사하였다. 자료는 총 53개 마을에서 50~90대까지 145명 주민들의 면담을 통해 수집하였다. 총 19개 야생버섯이 식용버섯으로 사용되었는데 싸리버섯이 식용버섯으로 가장 널리 이용되었고, 큰갓버섯과 표고 순위로 식용하였다. 표고는 식 약용버섯으로 유일하게 사용되었다. 독흰갈대버섯은 독버섯인데 곤충퇴치용 버섯으로 사용하고 있었다. 가장 다양한 버섯이 증언된 지역은 거제시 일운면으로 10종에 이르는 버섯의 전통지식이 확인되었고, 하동군의 진교면에서 8종이 출현하였다. 전통 지식에 대해 조사에 응한 여성이 남성에 비해 2배 이상 많이 증언하였고 연령층은 70~80대가 가장 많았다.

• 한국자원식물학회지
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• 제28권2호
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• pp.217-234
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• 2015

본 연구는 제주도 지역에서 이용되는 민속식물에 대한 전통지식 정보를 수집 및 보존을 위하여 2011년 3월부터 11월까지 수행되었다. 제주도지역의 78개소에서 주민 177명을 대상으로 수집한 조사야장 1,774장의 설문조사를 분석한 결과, 조사된 식물은 총 103과 260속 312종 2아종 37변종 5품종의 총 356분류군으로 정리되었다. 용도별 이용현황은 약용 284분류군, 식용 145분류군, 제례 36분류군, 생활용품 31분류군, 목재 31분류군 등으로 주로 약용의 빈도가 높았다. 이용 부위로는 잎, 줄기, 식물체 전체 순으로 나타났다. 또한 분류군별 이용 빈도를 분석한 결과, 질경이, 쑥, 인동 등의 순으로 확인되었다.

• Journal of Acupuncture Research
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• 제26권4호
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• pp.91-98
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• 2009

Objectives : The objective of this review is to introduce the basic concepts on the febrile disease in the Mongolian Traditional Medicine(MTM). Methods : We comprehensively reviewed related textbooks in Mongolian and articles searched from China National Knowledge Infrastructure(CNKI) on febrile disease about MTM and summarized the pathophysiologic basis of, and treatment principles in MTM. Results and Conclusions : 1. In MTM, there are basic concepts such as theory of Arga-Bilig, theory of five elements, theory of three elements(人體三素), theory of seven constitutions and three discharges(七元三濊). Most of all, theory of three elements, which is about the basic elements of human body in MTM, is important fundamental notions for explaining human physiology and pathology. In MTM, It is explained that the imbalance of three elements, namely khii, shar, bad-kan is the root of all disease. Especially, febrile disease is treated by suppressing activated shar and blood(血液), which have fire characters, and managing various additional symptoms by balancing three elements and eliminating miasma(邪氣), inappropriate substances such as bile water(shar yc, 黃水) or blood stasis(惡血) simultaneously. 2. In MTM, both of internal treatment modalities(various medicinal therapy) and external treatment modalities(physical therapy) have been used for febrile disease. Food therapy and life style modification also have been recognized as important treatment methods. These aspects correspond to wholism theory of Korean Traditional Medicine(KTM). Further studies about details of each treatment methods will discover new applicable treatment method and make broaden the external boundaries of the KTM.

• 동의신경정신과학회지
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• 제31권1호
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• pp.49-61
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• 2020

Objectives: The objective of this study is to analyze clinical reports of treatment of menopausal depression in traditional Chinese medicine (TCM). Methods: This study included randomized controlled trials (RCT) in treating menopausal depression. Literature studies of Chinese National Knowledge Infrastructure Database(CNKI) were performed. Clinical reports on menopausal depression treatment were searched using the following key words in the CNKI: 'menopausal depression' and 'postmenopausal depression'. Results and Conclusions: A total of 24 RCT articles on menopausal depression were selected. The most widely used diagnostic tool for menopausal depression was CCMD-3. Effective rate and HAMD were the most commonly used assessment tools. Bosinhaeultang-gagam (Bushenjieyu-tang jiajian) and Gami-gammaegdaejotang(Jiawei ganmaidazao-tang) were used much more than other prescriptions, while Bupleuri Radix was the most used single medicine herb. Additionally, the Chinese medicine treatment group showed less adverse reactions than the control group. As a result, we could know frequently used herbal prescription and single medicinal herbs and this can be helpful in developing more advanced studies in future.

• 한방안이비인후피부과학회지
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• 제31권3호
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• pp.12-25
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• 2018

Objectives : The purpose of this study is to analyze the use of herbal medicine for the treatment of urticaria in case studies and to find the general tendency of herbal medicine treatment and to establish the primary treatment direction of urticaria. Methods : In the domestic databases, Oriental medicine Advanced Searching Integrated System (OASIS), Korean Traditional Knowledge Portal (KTKP), National Discovery for Science Leader (NDSL), Research Information Sharing Service (RISS), we selected among the case study papers published in the last 20 years using search terms related to "urticaria". Reports related to Sasang Constitutional medicine were excluded and total of 15 papers were finally selected. Results : 23 prescriptions were retrieved from 15 papers. The most commonly used prescription was Seungmagalgeun-tang (升麻葛根湯), and Bangpoongtongsung-san (防風通聖散) and Pyeongwi-san (平胃散) were presented twice. Commonly used herbs are Glycyrrhizae Radix et Rhizoma (甘草), Zingiberis Rhizoma Recens (生薑), and Scutellariae Radix (黃芩). 18 out of 78 herbs are belonging to heat-clearing medicinal (淸熱藥) and 16 out of 78 herbs are belonging to exterior-releasing medicinal (解表藥). Concurrent therapies such as acupuncture, pharmacoacupuncture, moxibustion, cupping therapy, ice pack applying therapy were performed and several evaluation methods were used, patient's subjective remission rate was the most used. Conclusions : Through this study, we were able to discover the tendency of herbal medicine prescription for the treatment of urticaria.

• 한국자원식물학회지
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• 제29권1호
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• pp.62-89
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• 2016

민속식물과 그 이용에 대한 전통지식의 대부분은 사회 경제 변화의 결과로 빠르게 사라지고 있다. 따라서 이러한 전통 지식을 보존하고 탐색하기 위한 민속식물학적 연구가 요구되는 실정이다. 이에 본 연구는 한국 민속식물에 대한 전통지식의 발굴과 수집을 위하여 2006년부터 2014년까지 9년 동안 총 146개 시·군 868개소에서 1,771명(남 498, 여 1,275)을 대상으로 현지 설문조사를 수행하였다. 그 결과 설문자의 평균연령 69 ± 11.6세였고, 130과 493속 813종 7아종 92변종 12품종으로 총 924분류군의 민속식물이 정리되었으며, 17,328건의 전통지식 정보를 수집하였다. 그 중 초본식물 619분류군(67.0%), 목본식물 305분류군(33.0%)으로 확인되었다. 자생 및 재배식물 분석결과, 야생식물이 707종(76.5%)이었고, 야생식물의 재배종은 44종(4.8%), 재배를 위한 도입종은 145종(15.7%), 귀화식물은 28종(3.0%)으로 나타났다. 민속식물 924분류군에 대한 용도는 14종류로 확인되었으며, 그 중 식용이 58.9%로 가장 높았고, 약용 26.9%, 용재용 3.7%, 관상 2.3% 등의 순으로 확인되었다. 민속식물에 대한 부위별 이용비율은 잎이 38.6%로 가장 높았고, 뿌리 16.4%, 줄기 15.9%, 열매 10.9% 등의 순으로 나타났다. 또한 민속식물 924분류군의 전통지식에 대한 정량적 분석을 통하여 특정식물 종의 이용을 언급한 정보 보유자의 수(FC)와 이용범주 수(NU), 특정식물 이용자 수(UR), 상대적 인용빈도(RFC), 문화적 중요도 지수(CI), 상대적 중요도(RI), 문화적 가치(CV)를 산출하였다. 그 결과, 문화적 중요도(CI)는 쑥, 참취, 음나무, 상대적 인용빈도(RFC)는 참취, 쑥, 두릅나무, 상대적 중요도(RI)는 쑥, 소나무, 뽕나무, 문화적 가치(CV)는 쑥, 소나무, 음나무 등의 순으로 낮은 결과를 보였다.

• 한국자원식물학회지
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• 제27권4호
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• pp.309-325
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• 2014

본 연구는 2011년 3월부터 10월까지 충남 내륙지역을 중심으로 민속식물자원에 대한 전통지식 정보를 수집하여 수집된 이용정보를 국내 자생식물의 주권 확보를 위한 자료로 활용하고, 또한 이를 토대로 신물질 신소재 개발의 기초정보 제공과 지속적인 보전 및 관리의 기초자료로 이용하기 위해 수행하였다. 충남 내륙지역의 12개 시 군에서 지역주민 125명(남자 37, 여자 88)을 대상으로 민속식물 자원의 분포와 이용에 대한 설문조사를 실시한 결과, 민속식물자원은 92과 225속 237종 4아종 29변종 3품종 총 273분류군으로 확인되었다. 조사된 273분류군 중에는 특산식물 5분류군과 희귀식물 8분류군, 귀화식물 16분류군이 포함되어 있었고, 그 중 야생식물은 191분류군이었으며, 재배식물은 82분류군이었다. 용도별 이용현황은 식용 981건, 약용 439건, 용재용 179건, 유지용 68건 등으로 주로 식용의 빈도가 높았다. 이용 부위로는 잎, 줄기, 열매 등의 순으로 나타났으며, 연령별 표준식물명과 지방명의 일치성 여부를 분석한 결과 50대에서 가장 높았으며, 90대에서 가장 낮았다.

• Genomics & Informatics
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• 제12권4호
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• pp.156-164
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• 2014

Cancer is the most dreaded disease in human and also major health problem worldwide. Despite its high occurrence, the exact molecular mechanisms of the development and progression are not fully understood. The existing cancer therapy based on allopathic medicine is expensive, exhibits side effects; and may also alter the normal functioning of genes. Thus, a non-toxic and effective mode of treatment is needed to control cancer development and progression. Some medicinal plants offer a safe, effective and affordable remedy to control the cancer progression. Nimbolide, a limnoid derived from the neem (Azadirachta indica) leaves and flowers of neem, is widely used in traditional medical practices for treating various human diseases. Nimbolide exhibits several pharmacological effects among which its anticancer activity is the most promising. The previous studies carried out over the decades have shown that nimbolide inhibits cell proliferation and metastasis of cancer cells. This review highlights the current knowledge on the molecular targets that contribute to the observed anticancer activity of nimbolide related to induction of apoptosis and cell cycle arrest; and inhibition of signaling pathways related to cancer progression.

• 한국의사학회지
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• 제25권2호
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• pp.1-10
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• 2012

The late Goryeo and Early Joseon period marks the development of Hyang-yak medicine in medical history in Korea. There have been not a few outcomes in organizing Hyang-yak medicine through the hitherto research works, but there has hardly any attempt to view the medicine in the late Goryeo and Early Joseon period from a different standpoint besides Hyang-yak. This writer, in the middle of doing research on 'Book for Alimentotherapy' named "Sikuisikgam", came to know that not a few parts of this book were quoted in a large volume of "Biebaekyobang" in the late Goryeo, "Hyangyakjipseongbang" which compiled the early Joseon Hyangyak medicine, "Uibangyuchi" which wrapped up the medical knowledge in East Asia before the early Ming Dynasty, and "Sikryochangyo" which was a representative book for alimentotherapy in the early period of Joseon Dynasty. The reason that the representative medical books written in the period of Late Goryeo and Early Joseon thought much of the knowledge contained in "Sikuisikgam" is that they showed a great concern for prevention and treatment of diseases through alimentotherapy. When we say that Hyangyak medicine, which has provided the Late Goryeo and Early Joseon medicine, bases its standard on 'Regionality' and 'Properties of Medicinal ingredients', then alimentotherapy puts its focus on a 'Remedial method' itself. As for food, they might have given priority to the food that was easy to get nearby, so there is no way for alimentotherapy but to have the realm which is overlapped with Hyangyak medicine in some measure, That's the very reason why alimentotherapy has remained inseparate from Hyangyak medicine. Through 'Alimentotherapy' and Late Goryeo and Early Joseon medical books, this writer thinks that it might be possible for us to take a view of the Late Goryeo and Early Joseon not only from the perspective of Hyangyak medicine but also from a new perspective of so-called alimentotherapy.